NO20014624D0 - Fremgangsmåte for fremstilling av monoklonale antistoffer og fremgangsmåte for fremstilling av vaksine mot Lyme-sykdom(borreliose) - Google Patents

Fremgangsmåte for fremstilling av monoklonale antistoffer og fremgangsmåte for fremstilling av vaksine mot Lyme-sykdom(borreliose)

Info

Publication number: NO20014624D0
Authority: NO; Norway
Prior art keywords: lyme disease; borreliosis; preparation; monoclonal antibodies; preparing vaccine
Prior art date: 1989-09-19

Application number

NO20014624A

Other languages

English (en)

Other versions

NO315905B1 (no

NO20014624L (no

Inventor

Markus M Simon

Ulrich E Schaible

Klaus Eichmann

Michael Kramer

Wallich Reinhard

Original Assignee

Deutsches Krebsforsch

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-19

Filing date

2001-09-24

Publication date

2001-09-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25885304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20014624(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-03-20 Publication of NO20014624L publication Critical patent/NO20014624L/no

2001-09-24 Application filed by Deutsches Krebsforsch filed Critical Deutsches Krebsforsch

2001-09-24 Publication of NO20014624D0 publication Critical patent/NO20014624D0/no

2003-11-10 Publication of NO315905B1 publication Critical patent/NO315905B1/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Gram-negative bacteria
- C07K16/1207—Gram-negative bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Virology (AREA)
Microbiology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

NO20014624A 1989-09-19 2001-09-24 Fremgangsmåte for fremstilling av monoklonale antistoffer og fremgangsmåtefor fremstilling av passiv vaksine mot B. burgdorferi NO315905B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3931236		1989-09-19
DE4015911A DE4015911A1 (de)	1989-09-19	1990-05-17	Impfstoff gegen die lyme-krankheit

Publications (3)

Publication Number	Publication Date
NO20014624L NO20014624L (no)	1991-03-20
NO20014624D0 true NO20014624D0 (no)	2001-09-24
NO315905B1 NO315905B1 (no)	2003-11-10

Family

ID=25885304

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO19904062A NO311767B1 (no)	1989-09-19	1990-09-18	Patogen Borrelia burgdorferi-stamme, fremgangsmåte for fremstilling av et terapeutisk aktivt, isolert B. burgdorferi-OspA-antigen, rekombinant DNA, rekombinant vektor og fremgangsmåte forfremstilling av vaksine mot Lyme-sykdom (borreliose)
NO20014624A NO315905B1 (no)	1989-09-19	2001-09-24	Fremgangsmåte for fremstilling av monoklonale antistoffer og fremgangsmåtefor fremstilling av passiv vaksine mot B. burgdorferi

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NO19904062A NO311767B1 (no)	1989-09-19	1990-09-18	Patogen Borrelia burgdorferi-stamme, fremgangsmåte for fremstilling av et terapeutisk aktivt, isolert B. burgdorferi-OspA-antigen, rekombinant DNA, rekombinant vektor og fremgangsmåte forfremstilling av vaksine mot Lyme-sykdom (borreliose)

Country Status (23)

Country	Link
US (6)	US5178859A (no)
EP (5)	EP0418827B1 (no)
JP (3)	JP3205932B2 (no)
KR (2)	KR100205462B1 (no)
AT (4)	ATE175576T1 (no)
AU (1)	AU651560B2 (no)
CA (1)	CA2025597C (no)
CZ (2)	CZ284538B6 (no)
DE (5)	DE4015911A1 (no)
DK (4)	DK0633028T3 (no)
ES (4)	ES2129551T3 (no)
FI (1)	FI102248B1 (no)
GR (3)	GR3018995T3 (no)
HR (1)	HRP940545B1 (no)
HU (2)	HU212716B (no)
IE (1)	IE903377A1 (no)
NO (2)	NO311767B1 (no)
NZ (1)	NZ235260A (no)
PL (2)	PL170229B1 (no)
PT (1)	PT95349B (no)
SI (1)	SI9011773B (no)
SK (3)	SK283089B6 (no)
YU (2)	YU48250B (no)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK590288D0 (da)	1988-10-24	1988-10-24	Symbicom Ab	Kemiske forbindelser
US7094391B1 (en) *	1988-10-24	2006-08-22	The University Of Texas System	Compositions and methods for administering Borrelia burgdorferi antigens
US6143872A (en) *	1988-10-24	2000-11-07	Symbicom Aktiebolag	Borrelia burdorferi Osp A and B proteins and immunogenic peptides
US5777095A (en) *	1988-10-24	1998-07-07	Symbicom Aktiebolag	Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90
DE4015911A1 (de) *	1989-09-19	1991-03-28	Max Planck Gesellschaft	Impfstoff gegen die lyme-krankheit
US5582829A (en) *	1990-04-05	1996-12-10	Rx Technologies, Inc.	Sonicated borrelia burgdorferi vaccine
JPH06501382A (ja)	1990-06-15	1994-02-17	エールユニバーシティ	ライム病の予防および診断に用いる組成物および方法
EP1016416A3 (en) *	1990-07-06	2002-10-23	Wyeth	Vaccine against lyme disease and a challenge model for evaluating vaccine efficacy
CA2057536C (en) *	1990-12-21	1999-10-26	John J. Dunn	Cloning and expression of borrelia lipoproteins
US6872550B1 (en)	1991-07-11	2005-03-29	Baxter Vaccine Ag	Immunogenic formulation of OspC antigen vaccines for the prevention and treatment of lyme disease and recombinant methods for the preparation of such antigens
US6221363B1 (en) *	1991-07-11	2001-04-24	Baxter Aktiengesellschaft	Vaccine for the prevention of lyme disease
US6676942B1 (en)	1991-08-15	2004-01-13	Smithkline Beecham Biologicals (S.A.)	Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines
JPH07501687A (ja) *	1991-08-15	1995-02-23	スミスクライン・ビーチャム・バイオロジカルス（ソシエテ・アノニム）	ボレリア・ブルグドルフェリのサブグループのｏｓｐ　ａ　蛋白、それをコードしている遺伝子およびワクチン
PT100980B (pt) *	1991-10-18	1999-07-30	Connaught Lab	Proteinas recombinantes de borrelia, seu processo de producao, vacina contra infeccao por borrelia e agente de imunodiagnostico para a sua deteccao
AU2903892A (en) *	1991-10-22	1993-05-21	Symbicom Aktiebolag	Improvement in (borrelia burgdorferi) diagnosis and prophylaxis
US6303129B1 (en) *	1992-07-28	2001-10-16	Rx Technologies	Production of borrelia burgdorferi vaccine, product produced thereby and method of use
US5656451A (en) *	1993-07-30	1997-08-12	Yale University	OspE, OspF, and S1 polypeptides in borrelia burgdorferi
US6716591B1 (en)	1993-07-30	2004-04-06	Yale University	B. burgdorferi polypeptides
US7008625B2 (en)	1993-11-01	2006-03-07	Research Foundation Of The State University Of New York	Recombinant constructs of Borrelia burgdorferi
US5558993A (en) *	1994-06-17	1996-09-24	The Regents Of The University Of California	Cloned Borrelia burgdorferi virulence protein
GB9511909D0 (en) *	1995-06-12	1995-08-09	Microbiological Res Authority	Vaccine
US6437116B1 (en)	1996-02-21	2002-08-20	Board Of Regents, The University Of Texas System	VMP-like sequences of pathogenic borrelia
DE19632862B4 (de) *	1996-08-14	2006-08-03	Mikrogen Molekularbiologische Entwicklungs-Gmbh	Immunologisch aktive Proteine von Borrelia burgdorferi, dafür kodierende Nukleinsäuren sowie deren Verwendung in Testkits und als Impfstoffe
US6458555B1 (en) *	1996-08-21	2002-10-01	Gerd Bach	Cytologic method of examining mucous membranes
US6060082A (en) *	1997-04-18	2000-05-09	Massachusetts Institute Of Technology	Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
DE19740735A1 (de) *	1997-09-16	1999-03-18	Max Planck Gesellschaft	Arzneimittel zur Therapie einer manifesten Lyme-Borreliose
US6306623B1 (en)	1998-02-24	2001-10-23	The University Of California	Leptospiral major outer membrane protein LipL32
PT1100922E (pt)	1998-07-31	2008-05-30	Gundersen Lutheran Medical Fou	Utilização do(s) epítopo(s) borrelicida(s) da proteína de superfície externa c (ospc) de borrelia burgdorferi, como vacina
WO2000056298A2 (en) *	1999-03-19	2000-09-28	Luitpold Pharmaceuticals, Inc.	Treatment of lyme disease with polysulfated glycosaminoglycan formulations
US6592875B1 (en)	1999-06-21	2003-07-15	Milkhaus Laboratory, Inc.	Method for treatment of lyme disease
WO2002016421A2 (en)	2000-08-18	2002-02-28	Research Foundation Of The State University Of New York	Altered ospa of borrelia burgdorferi
EP2292762A3 (en)	2002-12-20	2012-12-12	Board of Regents, The University of Texas System	VMP-like sequences of pathogenic Borrelia species and strains
BRPI0719360B1 (pt)	2006-11-03	2016-09-06	Intervet Int Bv	vacina da doença de lyme canina, e, uso de organismos de uma genoespécie de borrelia
EP2361930A3 (en)	2007-03-26	2011-10-26	Dako Denmark A/S	Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases
EP3620465B1 (en)	2007-07-03	2025-02-19	Dako Denmark A/S	Improved methods for generation, labeling and use of mhc multimers
US10611818B2 (en)	2007-09-27	2020-04-07	Agilent Technologies, Inc.	MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
DK2254592T3 (da)	2008-02-28	2019-09-09	Dako Denmark As	MHC-multimerer til Borrelia-diagnostik og sygdom
US10722562B2 (en)	2008-07-23	2020-07-28	Immudex Aps	Combinatorial analysis and repair
GB0817244D0 (en)	2008-09-20	2008-10-29	Univ Cardiff	Use of a protein kinase inhibitor to detect immune cells, such as T cells
US11992518B2 (en)	2008-10-02	2024-05-28	Agilent Technologies, Inc.	Molecular vaccines for infectious disease
WO2010037402A1 (en)	2008-10-02	2010-04-08	Dako Denmark A/S	Molecular vaccines for infectious disease
AU2010322085B2 (en) *	2009-11-17	2016-09-15	Zoetis Services Llc	Peptides and methods for the detection of Lyme disease antibodies
US8758772B2 (en)	2011-11-04	2014-06-24	Abaxis, Inc.	Peptides and methods for the detection of lyme disease antibodies
PL223175B1 (pl)	2012-10-22	2016-10-31	Inst Chemii Bioorganicznej Polskiej Akademii Nauk	Szczepionka przeciw boreliozie, konstrukt genetyczny, rekombinowane białko, sposób otrzymywania konstruktu genetycznego, sposób otrzymywania szczepionki, sposób otrzymywania rekombinowanych białek, zastosowanie rekombinowanych białek do wytwarzania szczepionki przeciwko boreliozie
US9610336B1 (en) *	2014-07-16	2017-04-04	Amiram Katz	Immunotherapy for lyme disease
US12258373B2 (en)	2018-12-17	2025-03-25	Immudex Aps	Panel comprising Borrelia MHC multimers

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK590288D0 (da) *	1988-10-24	1988-10-24	Symbicom Ab	Kemiske forbindelser
US4772464A (en)	1985-08-01	1988-09-20	Miles Laboratories, Inc.	Protective antibodies to serotypic determinants of flagellar antigens
US4888276A (en) *	1986-06-26	1989-12-19	Minnesota Mining And Manufacturing Company	Method and composition for the diagnosis of Lyme disease
US4721617A (en)	1986-08-14	1988-01-26	Regents Of The University Of Minnesota	Vaccine against lyme disease
US5034515A (en) *	1987-09-22	1991-07-23	Wisconsin Alumni Research Foundation	Staphylococcal fibronectin receptor, monoclonal antibodies thereto and methods of use
DE4015911A1 (de) *	1989-09-19	1991-03-28	Max Planck Gesellschaft	Impfstoff gegen die lyme-krankheit
AU7058691A (en) *	1989-12-22	1991-07-24	Mikrogen Molekularbiologische Entwicklungs-Gmbh	Immunologically active proteines from borrelia burgdorferi, related test kits and vaccine
JPH06501382A (ja) *	1990-06-15	1994-02-17	エールユニバーシティ	ライム病の予防および診断に用いる組成物および方法
EP1016416A3 (en) *	1990-07-06	2002-10-23	Wyeth	Vaccine against lyme disease and a challenge model for evaluating vaccine efficacy
CA2057536C (en) *	1990-12-21	1999-10-26	John J. Dunn	Cloning and expression of borrelia lipoproteins
JPH07501687A (ja) *	1991-08-15	1995-02-23	スミスクライン・ビーチャム・バイオロジカルス（ソシエテ・アノニム）	ボレリア・ブルグドルフェリのサブグループのｏｓｐ　ａ　蛋白、それをコードしている遺伝子およびワクチン
JP3246603B2 (ja) *	1991-08-27	2002-01-15	ノボザイムスアクティーゼルスカブ	洗剤
PT100980B (pt) *	1991-10-18	1999-07-30	Connaught Lab	Proteinas recombinantes de borrelia, seu processo de producao, vacina contra infeccao por borrelia e agente de imunodiagnostico para a sua deteccao
WO1993007897A1 (en) *	1991-10-21	1993-04-29	Medimmune, Inc.	Bacterial expression vectors containing dna encoding secretion signals of lipoproteins

1990
- 1990-05-17 DE DE4015911A patent/DE4015911A1/de not_active Withdrawn
- 1990-09-07 HU HU905816A patent/HU212716B/hu not_active IP Right Cessation
- 1990-09-11 NZ NZ235260A patent/NZ235260A/xx unknown
- 1990-09-12 AU AU62444/90A patent/AU651560B2/en not_active Ceased
- 1990-09-18 AT AT94112143T patent/ATE175576T1/de not_active IP Right Cessation
- 1990-09-18 CA CA002025597A patent/CA2025597C/en not_active Expired - Fee Related
- 1990-09-18 FI FI904597A patent/FI102248B1/fi not_active IP Right Cessation
- 1990-09-18 ES ES94112143T patent/ES2129551T3/es not_active Expired - Lifetime
- 1990-09-18 EP EP90117943A patent/EP0418827B1/de not_active Expired - Lifetime
- 1990-09-18 ES ES94112145T patent/ES2141182T3/es not_active Expired - Lifetime
- 1990-09-18 DE DE59010863T patent/DE59010863D1/de not_active Expired - Fee Related
- 1990-09-18 EP EP98105444A patent/EP0861664A3/de not_active Withdrawn
- 1990-09-18 DE DE59010888T patent/DE59010888D1/de not_active Expired - Fee Related
- 1990-09-18 DK DK94112145T patent/DK0633028T3/da active
- 1990-09-18 DE DE59010903T patent/DE59010903D1/de not_active Expired - Fee Related
- 1990-09-18 EP EP94112144A patent/EP0633313B1/de not_active Expired - Lifetime
- 1990-09-18 DE DE59009978T patent/DE59009978D1/de not_active Expired - Fee Related
- 1990-09-18 SI SI9011773A patent/SI9011773B/sl not_active IP Right Cessation
- 1990-09-18 PL PL90307358A patent/PL170229B1/pl not_active IP Right Cessation
- 1990-09-18 ES ES94112144T patent/ES2145077T3/es not_active Expired - Lifetime
- 1990-09-18 DK DK94112144T patent/DK0633313T3/da active
- 1990-09-18 IE IE337790A patent/IE903377A1/en not_active IP Right Cessation
- 1990-09-18 DK DK94112143T patent/DK0643974T3/da active
- 1990-09-18 AT AT94112145T patent/ATE186646T1/de not_active IP Right Cessation
- 1990-09-18 NO NO19904062A patent/NO311767B1/no unknown
- 1990-09-18 AT AT94112144T patent/ATE191499T1/de not_active IP Right Cessation
- 1990-09-18 ES ES90117943T patent/ES2082812T3/es not_active Expired - Lifetime
- 1990-09-18 PL PL90286918A patent/PL169804B1/pl not_active IP Right Cessation
- 1990-09-18 EP EP94112143A patent/EP0643974B1/de not_active Expired - Lifetime
- 1990-09-18 EP EP94112145A patent/EP0633028B1/de not_active Expired - Lifetime
- 1990-09-18 AT AT90117943T patent/ATE131732T1/de not_active IP Right Cessation
- 1990-09-18 DK DK90117943.2T patent/DK0418827T3/da active
- 1990-09-18 YU YU177390A patent/YU48250B/sh unknown
- 1990-09-19 US US07/585,310 patent/US5178859A/en not_active Expired - Lifetime
- 1990-09-19 SK SK1511-98A patent/SK283089B6/sk unknown
- 1990-09-19 CZ CS904560A patent/CZ284538B6/cs not_active IP Right Cessation
- 1990-09-19 CZ CZ95970A patent/CZ284616B6/cs not_active IP Right Cessation
- 1990-09-19 KR KR1019900014814A patent/KR100205462B1/ko not_active Expired - Fee Related
- 1990-09-19 SK SK1510-98A patent/SK283088B6/sk unknown
- 1990-09-19 JP JP24765090A patent/JP3205932B2/ja not_active Expired - Fee Related
- 1990-09-19 PT PT95349A patent/PT95349B/pt active IP Right Grant
- 1990-09-19 SK SK4560-90A patent/SK456090A3/sk unknown
1993
- 1993-05-27 US US08/068,063 patent/US5434077A/en not_active Expired - Fee Related
1994
- 1994-09-15 HR HR940545A patent/HRP940545B1/xx not_active IP Right Cessation
1995
- 1995-03-20 US US08/406,623 patent/US5780030A/en not_active Expired - Fee Related
- 1995-03-20 US US08/407,350 patent/US5686267A/en not_active Expired - Lifetime
- 1995-04-24 HU HU95P/P00108P patent/HU211228A9/hu unknown
1996
- 1996-02-14 GR GR960400397T patent/GR3018995T3/el unknown
1997
- 1997-03-12 YU YU9097A patent/YU49370B/sh unknown
1998
- 1998-02-23 US US09/027,843 patent/US5856447A/en not_active Expired - Fee Related
- 1998-08-29 KR KR1019980035375A patent/KR100202128B1/ko not_active Expired - Fee Related
1999
- 1999-10-07 US US09/413,858 patent/US6613331B1/en not_active Expired - Fee Related
- 1999-11-30 GR GR990403104T patent/GR3032010T3/el unknown
2000
- 2000-06-14 GR GR20000401362T patent/GR3033675T3/el not_active IP Right Cessation
- 2000-07-26 JP JP2000225341A patent/JP3328644B2/ja not_active Expired - Fee Related
- 2000-12-11 JP JP2000376159A patent/JP3418171B2/ja not_active Expired - Fee Related
2001
- 2001-09-24 NO NO20014624A patent/NO315905B1/no unknown

Also Published As

Publication number	Publication date
US5686267A (en)	1997-11-11
HU212716B (en)	1996-10-28
EP0643974B1 (de)	1999-01-13
ES2129551T3 (es)	1999-06-16
YU49370B (sh)	2005-09-19
DE59010863D1 (de)	1999-02-25
HU211228A9 (en)	1995-11-28
DK0643974T3 (da)	1999-09-06
EP0633028B1 (de)	1999-11-17
JPH03209400A (ja)	1991-09-12
FI102248B (fi)	1998-11-13
NO315905B1 (no)	2003-11-10
PT95349B (pt)	1997-06-30
KR100202128B1 (en)	1999-06-15
HU905816D0 (en)	1991-03-28
SI9011773A (sl)	1998-04-30
JP3205932B2 (ja)	2001-09-04
EP0633313B1 (de)	2000-04-05
CZ456090A3 (cs)	1998-08-12
ATE186646T1 (de)	1999-12-15
EP0643974A1 (de)	1995-03-22
HK1002405A1 (en)	1998-08-21
NZ235260A (en)	1993-04-28
CZ284538B6 (cs)	1998-12-16
JP2001204467A (ja)	2001-07-31
FI904597A0 (fi)	1990-09-18
NO311767B1 (no)	2002-01-21
GR3032010T3 (en)	2000-03-31
DE59009978D1 (de)	1996-02-01
US6613331B1 (en)	2003-09-02
PL170229B1 (pl)	1996-11-29
ES2145077T3 (es)	2000-07-01
NO904062L (no)	1991-03-20
HRP940545A2 (en)	1997-04-30
HRP940545B1 (en)	2000-06-30
CZ284616B6 (cs)	1999-01-13
US5780030A (en)	1998-07-14
ATE175576T1 (de)	1999-01-15
EP0633028A1 (de)	1995-01-11
PT95349A (pt)	1991-05-22
AU6244490A (en)	1991-03-28
SK283088B6 (sk)	2003-02-04
DE4015911A1 (de)	1991-03-28
CA2025597A1 (en)	1991-03-20
JP2001069969A (ja)	2001-03-21
AU651560B2 (en)	1994-07-28
DK0633313T3 (da)	2000-07-24
CZ97095A3 (en)	1995-09-13
SK280285B6 (sk)	1999-11-08
US5856447A (en)	1999-01-05
JP3418171B2 (ja)	2003-06-16
EP0861664A2 (de)	1998-09-02
DE59010903D1 (de)	2000-05-11
US5178859A (en)	1993-01-12
FI102248B1 (fi)	1998-11-13
SI9011773B (en)	2001-12-31
EP0418827B1 (de)	1995-12-20
DK0418827T3 (da)	1996-05-06
ATE191499T1 (de)	2000-04-15
SK456090A3 (en)	1999-11-08
ES2141182T3 (es)	2000-03-16
KR100205462B1 (ko)	1999-07-01
HK1013620A1 (en)	1999-09-03
ES2082812T3 (es)	1996-04-01
YU48250B (sh)	1997-09-30
JP3328644B2 (ja)	2002-09-30
EP0418827A1 (de)	1991-03-27
IE990173A1 (en)	2000-11-01
YU9097A (sh)	1999-06-15
SK283089B6 (sk)	2003-02-04
GR3033675T3 (en)	2000-10-31
SK151098A3 (en)	1999-04-13
DE59010888D1 (de)	1999-12-23
PL169804B1 (pl)	1996-09-30
KR910005889A (ko)	1991-04-27
YU177390A (sh)	1993-05-28
CA2025597C (en)	2004-02-03
ATE131732T1 (de)	1996-01-15
EP0633313A1 (de)	1995-01-11
EP0861664A3 (de)	1999-02-24
NO904062D0 (no)	1990-09-18
US5434077A (en)	1995-07-18
IE903377A1 (en)	1991-04-10
SK151198A3 (en)	1999-04-13
GR3018995T3 (en)	1996-05-31
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DK0633028T3 (da)	2000-04-10
NO20014624L (no)	1991-03-20

Publication	Publication Date	Title
NO20014624L (no)	1991-03-20	Fremgangsmåte for fremstilling av monoklonale antistoffer og fremgangsmåte for fremstilling av vaksine mot Lyme-sykdom(borreliose)
CY1111831T1 (el)	2015-10-07	Παραγωγα ογκο-συναφους αντιγονου απο την οικογενεια mage και αλληλουχιες νουκλεϊνικου οξεος που κωδικοποιουν αυτα, που χρησιμοποιουνται για την παρασκευη πρωτεϊνων συντηξης και συνθεσεων για εμβολιασμο
NO20020491D0 (no)	2002-01-30	CTL4A-reseptor, fusjonsproteiner som inneholder den og anvendelser derav
PT100781A (pt)	1993-09-30	Sequencias de dna codificadoras de proteinas de superficie externa, proteinas contendo as referidas sequencias, obtidas a partir de borrelia burgdorferi, e vacinas contendo as referidas proteinas
RU93058563A (ru)	1996-12-27	Полипептиды, иммунореагент, способ определения антител, способ индукции иммунного ответа, композиции, способ получения полипептида
ATE263836T1 (de)	2004-04-15	Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür
DK0469045T3 (da)	1994-09-26	Syntetiske Pseudomonas aeruginosa pilinpeptider og beslægtede vacciner diagnostica
CA2217522A1 (en)	1996-10-10	Isolated frpb nucleic acid molecule and vaccine
NO954318L (no)	1995-12-29	Immunogent preparat av OspC-antigenvaksiner for forhindring og behandling av Lymesykdom, samt rekombinante fremgangsmåter for fremstilling av slike antigener
DK398683A (da)	1984-03-03	Fremgangsmaade til fremstilling af antistoffer
CA1272124C (en)	1990-07-31	Marginal Anaplasma Subunit Antigen for Vaccination and Diagnostic Purposes
DK0513565T3 (da)	1997-03-24	Monoklonale antistoffer mod plasmin-antiplasmin-komplekset, fremgangsmåde til deres fremstilling og deres anvendelse
RU95117092A (ru)	1997-03-27	Антитела, смесь антител, fab-фрагмент, линии гибридомных клеток, способы создания линий клеток, способ борьбы с вирусом, способ снижения уровня антигена, днк
CA2347278A1 (en)	2000-04-06	Vaccine based on attenuated haemophilus somnus
RU95104722A (ru)	1996-12-20	Способ получения антител к коринебактериям дифтерии