NO20021781L - Heteroalkylamino-substituerte bicykliske nitrogenheterocykler som inhibitorer for P38-proteinkinase - Google Patents

Heteroalkylamino-substituerte bicykliske nitrogenheterocykler som inhibitorer for P38-proteinkinase

Info

Publication number
NO20021781L
NO20021781L NO20021781A NO20021781A NO20021781L NO 20021781 L NO20021781 L NO 20021781L NO 20021781 A NO20021781 A NO 20021781A NO 20021781 A NO20021781 A NO 20021781A NO 20021781 L NO20021781 L NO 20021781L
Authority
NO
Norway
Prior art keywords
inhibitors
heteroalkylamino
protein kinase
substituted bicyclic
nitrogen heterocycles
Prior art date
Application number
NO20021781A
Other languages
English (en)
Other versions
NO20021781D0 (no
Inventor
James Patrick Dunn
Lawrence Emerson Fisher
David Michael Goldstein
William Harris
Christopher Huw Hill
Ian Edward David Smith
Teresa Rosanne Welch
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20021781D0 publication Critical patent/NO20021781D0/no
Publication of NO20021781L publication Critical patent/NO20021781L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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Abstract

Oppfinnelsen tilveiebringer forbindelser representert ved formelen (I) hvor R ,2,og n er som definert i søknaden; og individuelle isomerer, racemiske eller ikke-racemiske blandinger av isomerer og farmasøytisk akseptable salter derav. Forbindelsene er p38-inhibitorer og kan anvendes ved behandling av artritt, Crohn's sykdom, irritert-tarm-syndrom, voksen åndenødssyndrom, kronisk obstruktiv pulmonal sykdom, osteoporose eller Alzheimers sykdom.
NO20021781A 1999-10-21 2002-04-16 Heteroalkylamino-substituerte bicykliske nitrogenheterocykler som inhibitorer for P38-proteinkinase NO20021781L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16080399P 1999-10-21 1999-10-21
US21374300P 2000-06-22 2000-06-22
PCT/EP2000/010088 WO2001029042A1 (en) 1999-10-21 2000-10-13 Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase

Publications (2)

Publication Number Publication Date
NO20021781D0 NO20021781D0 (no) 2002-04-16
NO20021781L true NO20021781L (no) 2002-04-18

Family

ID=26857240

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021781A NO20021781L (no) 1999-10-21 2002-04-16 Heteroalkylamino-substituerte bicykliske nitrogenheterocykler som inhibitorer for P38-proteinkinase

Country Status (26)

Country Link
US (1) US6451804B1 (no)
EP (1) EP1228070B1 (no)
JP (1) JP3961830B2 (no)
KR (1) KR100523120B1 (no)
CN (1) CN1171889C (no)
AR (1) AR026084A1 (no)
AT (1) ATE353329T1 (no)
AU (1) AU776250B2 (no)
BR (1) BR0015243A (no)
CA (1) CA2388142C (no)
CZ (1) CZ20021744A3 (no)
DE (1) DE60033307T2 (no)
ES (1) ES2280247T3 (no)
HR (1) HRP20020328A2 (no)
HU (1) HUP0203564A3 (no)
IL (1) IL149100A0 (no)
MA (1) MA26837A1 (no)
MX (1) MXPA02003950A (no)
NO (1) NO20021781L (no)
NZ (1) NZ518119A (no)
PE (1) PE20010758A1 (no)
PL (1) PL357502A1 (no)
RU (1) RU2265606C2 (no)
TR (1) TR200201057T2 (no)
WO (1) WO2001029042A1 (no)
YU (1) YU29102A (no)

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