NO20033058D0 - Prosess - Google Patents
ProsessInfo
- Publication number
- NO20033058D0 NO20033058D0 NO20033058A NO20033058A NO20033058D0 NO 20033058 D0 NO20033058 D0 NO 20033058D0 NO 20033058 A NO20033058 A NO 20033058A NO 20033058 A NO20033058 A NO 20033058A NO 20033058 D0 NO20033058 D0 NO 20033058D0
- Authority
- NO
- Norway
- Prior art keywords
- sub
- dihydroxypropyl
- triiodoisophtalamide
- monoalkylether
- iohexol
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- NTHXOOBQLCIOLC-UHFFFAOYSA-N iohexol Chemical compound OCC(O)CN(C(=O)C)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I NTHXOOBQLCIOLC-UHFFFAOYSA-N 0.000 abstract 1
- 229960001025 iohexol Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20033058A NO20033058D0 (no) | 2003-07-03 | 2003-07-03 | Prosess |
| US10/560,497 US20060178533A1 (en) | 2003-07-03 | 2004-07-01 | Process for iohexol manufacture |
| PCT/NO2004/000199 WO2005003080A1 (en) | 2003-07-03 | 2004-07-01 | Process for iohexol manufacture |
| ES04748775T ES2314414T3 (es) | 2003-07-03 | 2004-07-01 | Procedimiento para la preparacion de iohexol. |
| DE602004017729T DE602004017729D1 (de) | 2003-07-03 | 2004-07-01 | Verfahren zur herstellung von iohexol |
| EP04748775A EP1641743B1 (de) | 2003-07-03 | 2004-07-01 | Verfahren zur herstellung von iohexol |
| KR1020067000051A KR101083147B1 (ko) | 2003-07-03 | 2004-07-01 | 요오헥솔의 제조 방법 |
| JP2006517004A JP4933253B2 (ja) | 2003-07-03 | 2004-07-01 | イオヘキソールの製造方法 |
| AT04748775T ATE414057T1 (de) | 2003-07-03 | 2004-07-01 | Verfahren zur herstellung von iohexol |
| CNB2004800191766A CN100349858C (zh) | 2003-07-03 | 2004-07-01 | 碘海醇的生产方法 |
| PT04748775T PT1641743E (pt) | 2003-07-03 | 2004-07-01 | Processo para a produção de iohexol |
| NO20056040A NO331657B1 (no) | 2003-07-03 | 2005-12-19 | Fremgangsmate for fremstilling av iohexol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20033058A NO20033058D0 (no) | 2003-07-03 | 2003-07-03 | Prosess |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20033058D0 true NO20033058D0 (no) | 2003-07-03 |
Family
ID=27800766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20033058A NO20033058D0 (no) | 2003-07-03 | 2003-07-03 | Prosess |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060178533A1 (de) |
| EP (1) | EP1641743B1 (de) |
| JP (1) | JP4933253B2 (de) |
| KR (1) | KR101083147B1 (de) |
| CN (1) | CN100349858C (de) |
| AT (1) | ATE414057T1 (de) |
| DE (1) | DE602004017729D1 (de) |
| ES (1) | ES2314414T3 (de) |
| NO (1) | NO20033058D0 (de) |
| PT (1) | PT1641743E (de) |
| WO (1) | WO2005003080A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO342021B1 (no) * | 2005-07-29 | 2018-03-12 | Ge Healthcare As | Kontinuerlig krystalliseringsprosess |
| NO20053687D0 (no) * | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process. |
| NO20053676D0 (no) * | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process |
| PT103391B (pt) * | 2005-11-24 | 2008-10-30 | Hovione Farmaciencia S A | Processo para fabrico de lohexol |
| CN101195587B (zh) * | 2006-12-19 | 2010-07-21 | 浙江尖峰海洲制药有限公司 | 一种碘克沙醇水解物的制备方法 |
| WO2011041275A1 (en) * | 2009-09-30 | 2011-04-07 | Mallinckrodt Inc. | Alkylation of triiodo-substituted arylamides in an aqueous mixed solvent system |
| KR101699226B1 (ko) * | 2009-11-26 | 2017-01-24 | 호비온 차이나 홀딩 리미티드 | 이오딕사놀의 제조 및 정제 |
| US9474808B2 (en) * | 2010-12-21 | 2016-10-25 | Ge Healthcare As | Desalination of a composition comprising a contrast agent |
| US20140065076A1 (en) * | 2012-08-30 | 2014-03-06 | Otsuka Pharmaceutical Co. Ltd. | Container with concentrated substance and method of using the same |
| CN110054569B (zh) * | 2019-05-17 | 2022-05-17 | 浙江海洲制药有限公司 | 一种制备碘海醇的方法 |
| CN110590591B (zh) * | 2019-09-25 | 2022-05-17 | 浙江海洲制药有限公司 | 一种碘克沙醇，碘海醇杂质的制备方法 |
| CN115403481A (zh) * | 2022-04-13 | 2022-11-29 | 江苏宇田医药有限公司 | 一种通过离子交换树脂纯化碘海醇的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9618056D0 (en) * | 1996-08-29 | 1996-10-09 | Nycomed Imaging As | Process |
| US5847212A (en) * | 1997-04-21 | 1998-12-08 | Abbott Laboratories | Process for the preparation of iohexol |
| GB9725010D0 (en) * | 1997-11-26 | 1998-01-28 | Nycomed Imaging As | Process |
| ITMI20010773A1 (it) * | 2001-04-11 | 2002-10-11 | Chemi Spa | Processo per la produzione di ioexolo ad elevata purezza |
-
2003
- 2003-07-03 NO NO20033058A patent/NO20033058D0/no unknown
-
2004
- 2004-07-01 CN CNB2004800191766A patent/CN100349858C/zh not_active Expired - Lifetime
- 2004-07-01 KR KR1020067000051A patent/KR101083147B1/ko not_active Expired - Lifetime
- 2004-07-01 JP JP2006517004A patent/JP4933253B2/ja not_active Expired - Lifetime
- 2004-07-01 EP EP04748775A patent/EP1641743B1/de not_active Expired - Lifetime
- 2004-07-01 DE DE602004017729T patent/DE602004017729D1/de not_active Expired - Lifetime
- 2004-07-01 WO PCT/NO2004/000199 patent/WO2005003080A1/en not_active Ceased
- 2004-07-01 AT AT04748775T patent/ATE414057T1/de not_active IP Right Cessation
- 2004-07-01 PT PT04748775T patent/PT1641743E/pt unknown
- 2004-07-01 US US10/560,497 patent/US20060178533A1/en not_active Abandoned
- 2004-07-01 ES ES04748775T patent/ES2314414T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR20060041207A (ko) | 2006-05-11 |
| EP1641743B1 (de) | 2008-11-12 |
| WO2005003080A1 (en) | 2005-01-13 |
| CN100349858C (zh) | 2007-11-21 |
| DE602004017729D1 (de) | 2008-12-24 |
| EP1641743A1 (de) | 2006-04-05 |
| ES2314414T3 (es) | 2009-03-16 |
| KR101083147B1 (ko) | 2011-11-11 |
| PT1641743E (pt) | 2008-12-30 |
| US20060178533A1 (en) | 2006-08-10 |
| JP2007521262A (ja) | 2007-08-02 |
| JP4933253B2 (ja) | 2012-05-16 |
| CN1816519A (zh) | 2006-08-09 |
| ATE414057T1 (de) | 2008-11-15 |
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