NO20034023L - 4-(2-butylamino)-2,7-dimetyl-8-(2-metyl-6-metoksypyrid-3- yl)pyrazolo-[1,5-A]-1,3,5-triazin, dens enantiomerer og farmasöytisk akseptablesalter som kortikotropinfrigivende faktorreseptorligander - Google Patents

4-(2-butylamino)-2,7-dimetyl-8-(2-metyl-6-metoksypyrid-3- yl)pyrazolo-[1,5-A]-1,3,5-triazin, dens enantiomerer og farmasöytisk akseptablesalter som kortikotropinfrigivende faktorreseptorligander

Info

Publication number: NO20034023L
Authority: NO; Norway
Prior art keywords: methoxypyrid; pyrazolo; butylamino; enantiomers; triazine
Prior art date: 2001-03-13

Application number

NO20034023A

Other languages

English (en)

Other versions

NO20034023D0 (no

NO328580B1 (no

Inventor

Paul Joseph Gilligan

Original Assignee

Bristol Myers Squibb Pharma Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-13

Filing date

2003-09-11

Publication date

2003-09-11

2003-09-11 Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co

2003-09-11 Publication of NO20034023D0 publication Critical patent/NO20034023D0/no

2003-09-11 Publication of NO20034023L publication Critical patent/NO20034023L/no

2010-03-22 Publication of NO328580B1 publication Critical patent/NO328580B1/no

Links

HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
108010056643 Corticotropin-Releasing Hormone Receptors Proteins 0.000 title 1
102100038018 Corticotropin-releasing factor receptor 1 Human genes 0.000 title 1
239000003446 ligand Substances 0.000 title 1
LBWQSAZEYIZZCE-UHFFFAOYSA-N n-butan-2-yl-8-(6-methoxy-2-methylpyridin-3-yl)-2,7-dimethylpyrazolo[1,5-a][1,3,5]triazin-4-amine Chemical compound CC1=NN2C(NC(C)CC)=NC(C)=NC2=C1C1=CC=C(OC)N=C1C LBWQSAZEYIZZCE-UHFFFAOYSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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NO20034023A 2001-03-13 2003-09-11 4-(2-butylamino)-2,7-dimetyl-8-(2-metyl-6-metoksypyrid-3-yl)pyrazolo-[1,5-A]-1,3,5-triazin, et farmasoytisk akseptabelt promedikament derav, farmasoytisk preparat, anvendelse av forbindelsen samt fremstilt gjenstand omfattende denne NO328580B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US27540301P	2001-03-13	2001-03-13
PCT/US2002/006837 WO2002072202A1 (en)	2001-03-13	2002-03-06	4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl) pyrazolo-[1,5-a]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands

Publications (3)

Publication Number	Publication Date
NO20034023D0 NO20034023D0 (no)	2003-09-11
NO20034023L true NO20034023L (no)	2003-09-11
NO328580B1 NO328580B1 (no)	2010-03-22

Family

ID=23052141

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20034023A NO328580B1 (no)	2001-03-13	2003-09-11	4-(2-butylamino)-2,7-dimetyl-8-(2-metyl-6-metoksypyrid-3-yl)pyrazolo-[1,5-A]-1,3,5-triazin, et farmasoytisk akseptabelt promedikament derav, farmasoytisk preparat, anvendelse av forbindelsen samt fremstilt gjenstand omfattende denne

Country Status (35)

Country	Link
US (4)	US20030125330A1 (no)
EP (1)	EP1368094B1 (no)
JP (1)	JP4549630B2 (no)
KR (1)	KR100875595B1 (no)
CN (1)	CN100427093C (no)
AR (1)	AR032986A1 (no)
AT (1)	ATE355102T1 (no)
AU (1)	AU2002245605B2 (no)
BG (1)	BG66331B1 (no)
BR (1)	BR0208357A (no)
CA (1)	CA2440553C (no)
CY (1)	CY1106607T1 (no)
CZ (1)	CZ20032481A3 (no)
DE (1)	DE60218434T2 (no)
DK (1)	DK1368094T3 (no)
EE (1)	EE05433B1 (no)
ES (1)	ES2282401T3 (no)
GE (1)	GEP20053608B (no)
HR (1)	HRP20030822B1 (no)
HU (1)	HU229317B1 (no)
IL (2)	IL157615A0 (no)
IS (1)	IS2839B (no)
MX (1)	MXPA03008185A (no)
MY (1)	MY146935A (no)
NO (1)	NO328580B1 (no)
NZ (1)	NZ528207A (no)
PL (1)	PL208278B1 (no)
PT (1)	PT1368094E (no)
RS (1)	RS50863B (no)
RU (1)	RU2292347C2 (no)
SK (1)	SK287603B6 (no)
TW (1)	TWI257388B (no)
UA (1)	UA74634C2 (no)
WO (1)	WO2002072202A1 (no)
ZA (1)	ZA200306995B (no)

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WO2014078568A1 (en)	2012-11-14	2014-05-22	The Johns Hopkins University	Methods and compositions for treating schizophrenia
GB201310782D0 (en)	2013-06-17	2013-07-31	Max Planck Innovation Gmbh	Method for predicting a treatment response to a CRHR1 antagonist and/or V1B antagonist in a patient with depressive and/or anxiety symptoms
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KR20250022913A (ko)	2017-08-14	2025-02-17	스프루스 바이오사이언시스 인코포레이티드	코티코트로핀 방출 인자 수용체 길항제
CN112423747A (zh)	2018-04-27	2021-02-26	云杉生物科学公司	用于治疗睾丸肾上腺残余瘤和卵巢肾上腺残余瘤的方法
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2002
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Also Published As

Publication number	Publication date
AR032986A1 (es)	2003-12-03
PT1368094E (pt)	2007-05-31
NO20034023D0 (no)	2003-09-11
DE60218434D1 (en)	2007-04-12
WO2002072202A1 (en)	2002-09-19
PL368644A1 (en)	2005-04-04
HRP20030822B1 (en)	2008-01-31
YU71503A (sh)	2006-05-25
JP4549630B2 (ja)	2010-09-22
HK1057182A1 (en)	2004-03-19
UA74634C2 (uk)	2006-01-16
PL208278B1 (pl)	2011-04-29
ES2282401T3 (es)	2007-10-16
SK11572003A3 (sk)	2004-02-03
US7358252B2 (en)	2008-04-15
BG108189A (bg)	2004-09-30
EE200300435A (et)	2003-12-15
AU2002245605B2 (en)	2006-02-02
RS50863B (sr)	2010-08-31
IS2839B (is)	2013-06-15
NZ528207A (en)	2006-02-24
EP1368094B1 (en)	2007-02-28
US20080139567A1 (en)	2008-06-12
CA2440553C (en)	2010-06-08
HU229317B1 (en)	2013-10-28
HRP20030822A2 (en)	2004-04-30
EP1368094A1 (en)	2003-12-10
ATE355102T1 (de)	2006-03-15
KR100875595B1 (ko)	2008-12-23
CZ20032481A3 (cs)	2007-12-27
NO328580B1 (no)	2010-03-22
MXPA03008185A (es)	2004-01-29
US7662817B2 (en)	2010-02-16
RU2003130093A (ru)	2005-03-20
HUP0303480A3 (en)	2005-12-28
KR20030080086A (ko)	2003-10-10
CN100427093C (zh)	2008-10-22
RU2292347C2 (ru)	2007-01-27
US20030125330A1 (en)	2003-07-03
IS6947A (is)	2003-09-10
US20070054913A1 (en)	2007-03-08
BG66331B1 (bg)	2013-06-28
JP2004530662A (ja)	2004-10-07
CN1509196A (zh)	2004-06-30
EE05433B1 (et)	2011-06-15
CA2440553A1 (en)	2002-09-19
HUP0303480A2 (hu)	2004-01-28
BR0208357A (pt)	2004-06-29
MY146935A (en)	2012-10-15
IL157615A (en)	2009-09-01
IL157615A0 (en)	2004-03-28
DE60218434T2 (de)	2007-11-08
TWI257388B (en)	2006-07-01
US7157578B2 (en)	2007-01-02
SK287603B6 (sk)	2011-03-04
DK1368094T3 (da)	2007-07-02
ZA200306995B (en)	2004-09-08
GEP20053608B (en)	2005-09-12
EP1368094A4 (en)	2004-03-31
US20040014760A1 (en)	2004-01-22
CY1106607T1 (el)	2012-01-25

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Publication	Publication Date	Title
NO20034023D0 (no)	2003-09-11	4-(2-butylamino)-2,7-dimetyl-8-(2-metyl-6-metoksypyrid-3- yl)pyrazolo-[1,5-A]-1,3,5-triazin, dens enantiomerer og farmasöytisk akseptablesalter som kortikotropinfrigivende faktorreseptorligander
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ATE294180T1 (de)	2005-05-15	Substituierte 3,4-dihydro-pyrimido (1,2- a)pyrimidine und 3,4-dihydropyrazino (1,2- a)pyrimidine
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