NO20041590L - Karbonylbenzoksasinforbindelser for forbedrelse av glutamatergiske synapseresponser - Google Patents

Karbonylbenzoksasinforbindelser for forbedrelse av glutamatergiske synapseresponser

Info

Publication number
NO20041590L
NO20041590L NO20041590A NO20041590A NO20041590L NO 20041590 L NO20041590 L NO 20041590L NO 20041590 A NO20041590 A NO 20041590A NO 20041590 A NO20041590 A NO 20041590A NO 20041590 L NO20041590 L NO 20041590L
Authority
NO
Norway
Prior art keywords
carbonyl
responses
benzoxazine compounds
glutamatergic synapse
enhancing glutamatergic
Prior art date
Application number
NO20041590A
Other languages
English (en)
Norwegian (no)
Inventor
Christopher M Marrs
Gary A Rogers
Matthew Allan
Clayton Harris
Jianjie Huang
Original Assignee
Cortex Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortex Pharma Inc filed Critical Cortex Pharma Inc
Publication of NO20041590L publication Critical patent/NO20041590L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20041590A 2001-11-26 2004-04-19 Karbonylbenzoksasinforbindelser for forbedrelse av glutamatergiske synapseresponser NO20041590L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33333401P 2001-11-26 2001-11-26
PCT/US2002/037646 WO2003045315A2 (en) 2001-11-26 2002-11-25 Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses

Publications (1)

Publication Number Publication Date
NO20041590L true NO20041590L (no) 2004-07-12

Family

ID=23302344

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20041590A NO20041590L (no) 2001-11-26 2004-04-19 Karbonylbenzoksasinforbindelser for forbedrelse av glutamatergiske synapseresponser

Country Status (23)

Country Link
US (1) US7799913B2 (pl)
EP (1) EP1448537A4 (pl)
JP (1) JP4620349B2 (pl)
KR (1) KR100915176B1 (pl)
CN (1) CN1620440A (pl)
AU (1) AU2002352886B2 (pl)
BR (1) BR0214425A (pl)
CA (1) CA2463592A1 (pl)
CZ (1) CZ2004632A3 (pl)
EA (1) EA011034B1 (pl)
GE (1) GEP20063859B (pl)
HR (1) HRP20040424A2 (pl)
HU (1) HUP0402279A3 (pl)
IL (1) IL161452A0 (pl)
MA (1) MA26233A1 (pl)
MX (1) MXPA04004815A (pl)
NO (1) NO20041590L (pl)
NZ (1) NZ532368A (pl)
PL (1) PL371722A1 (pl)
SK (1) SK2292004A3 (pl)
UA (1) UA79940C2 (pl)
WO (1) WO2003045315A2 (pl)
ZA (1) ZA200403729B (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007342364A1 (en) * 2007-01-03 2008-07-17 Cortex Pharmaceuticals, Inc. 3-substituted-[1,2,3]benzotriazinone compounds for enhancing glutamatergic synaptic responses
MY154877A (en) * 2007-01-03 2015-08-14 Servier Lab 3-substituted-[1,2,3]-benzotriazinone compound for enhancing glutamateric synaptic responses
US20130058915A1 (en) 2010-03-02 2013-03-07 Children's Medica Center Corporation Methods and compositions for treatment of angelman syndrome and autism spectrum disorders
WO2012170845A2 (en) * 2011-06-08 2012-12-13 Heffernan Michele L R Metabotropic glutamate receptor 5 modulators and methods of use thereof
BR112015031249A2 (pt) 2013-06-13 2017-07-25 Veroscience Llc método de tratamento, método para tratar um distúrbio metabólico ou um elemento chave do mesmo, método para normalizar um ritmo diário de liberação de dopamina no sumn, método para estimular a liberação de dopamina de neurônios dopaminérgicos no sumn de um indivíduo e composição farmacêutica
KR20180019234A (ko) 2015-06-26 2018-02-23 다케다 야쿠힌 고교 가부시키가이샤 콜린성 무스카린 m1 수용체의 조절제로서의 2,3-디히드로-4h-1,3-벤족사진-4-온 유도체
JP6787913B2 (ja) 2015-10-20 2020-11-18 武田薬品工業株式会社 複素環化合物
US20190112300A1 (en) 2016-03-29 2019-04-18 Arnold Stan Lippa Compositions And Methods For Treating Attention Deficit Disorders
JP7365332B2 (ja) 2017-08-07 2023-10-19 ジョイント・ストック・カンパニー “バイオキャド” Ｃｄｋ８／１９阻害薬としての新規ヘテロ環式化合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2943087A (en) * 1960-06-28 n naoh
DE1122531B (de) * 1957-09-13 1962-01-25 Thomae Gmbh Dr K Verfahren zur Herstellung von therapeutisch wertvollen 4-Oxo-2-(halogenalkyl)-2,3-dihydro-benzoxazinen-(1,3)
US4022139A (en) * 1975-10-28 1977-05-10 Blue Bell, Inc. Tacker guide and method
EP0010348A1 (en) * 1978-09-12 1980-04-30 Imperial Chemical Industries Plc Heterocyclic trichloromethyl derivatives, process for their preparation and their use
JPH0597824A (ja) * 1990-09-25 1993-04-20 Takeda Chem Ind Ltd １，３−ベンゾオキサジン誘導体
EP1156043B1 (en) 1992-07-24 2003-11-12 The Regents Of The University Of California Drugs that enhance synaptic responses mediated by ampa receptors
US5650409A (en) 1995-06-02 1997-07-22 Cortex Pharmaceuticals, Inc. Benzoyl piperidines/pyrrolidines for enhancing synaptic response
US5736543A (en) 1996-04-03 1998-04-07 The Regents Of The University Of California Benzoxazines for enhancing synaptic response
GB9716962D0 (en) * 1997-08-12 1997-10-15 Univ Birmingham Liver function test
WO1999016758A1 (en) * 1997-10-27 1999-04-08 Dr. Reddy's Research Foundation Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
CA2320354A1 (en) * 1998-02-18 1999-08-26 Neurosearch A/S Novel compounds and their use as positive ampa receptor modulators
US6124278A (en) 1998-04-03 2000-09-26 The Regents Of The University Of California Acylbenzoxazines for enhancing synaptic response

Also Published As

Publication number Publication date
BR0214425A (pt) 2004-11-03
HRP20040424A2 (en) 2005-06-30
SK2292004A3 (en) 2004-09-08
ZA200403729B (en) 2005-05-19
IL161452A0 (en) 2004-09-27
CZ2004632A3 (cs) 2004-08-18
CN1620440A (zh) 2005-05-25
EP1448537A2 (en) 2004-08-25
EP1448537A4 (en) 2005-05-04
CA2463592A1 (en) 2003-06-05
UA79940C2 (en) 2007-08-10
EA011034B1 (ru) 2008-12-30
US7799913B2 (en) 2010-09-21
JP2005510532A (ja) 2005-04-21
MXPA04004815A (es) 2005-02-17
EA200400584A1 (ru) 2005-02-24
AU2002352886B2 (en) 2008-10-16
NZ532368A (en) 2006-10-27
PL371722A1 (pl) 2005-06-27
HUP0402279A3 (en) 2008-09-29
MA26233A1 (fr) 2004-07-01
US20040259871A1 (en) 2004-12-23
WO2003045315A2 (en) 2003-06-05
JP4620349B2 (ja) 2011-01-26
HUP0402279A2 (hu) 2005-02-28
KR20040054777A (ko) 2004-06-25
GEP20063859B (en) 2006-06-26
AU2002352886A1 (en) 2003-06-10
WO2003045315A3 (en) 2003-08-28
KR100915176B1 (ko) 2009-09-03

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