NO20050871L - 6-amino-1H-indazol- og 4-aminobenzofuranforbindelser som fosfodiesterase 4-inhibitorer - Google Patents

6-amino-1H-indazol- og 4-aminobenzofuranforbindelser som fosfodiesterase 4-inhibitorer

Info

Publication number: NO20050871L
Authority: NO; Norway
Prior art keywords: indazole; phosphodiesterase; inhibitors; amino; compounds
Prior art date: 2002-07-19

Application number

NO20050871A

Other languages

English (en)

Norwegian (no)

Inventor

Richard A Schumacher

Ashok Tehim

Allen T Hopper

Original Assignee

Memory Pharm Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-19

Filing date

2005-02-18

Publication date

2005-02-18

2005-02-18 Application filed by Memory Pharm Corp filed Critical Memory Pharm Corp

2005-02-18 Publication of NO20050871L publication Critical patent/NO20050871L/no

Links

OCZGGFAZAPGFMC-UHFFFAOYSA-N 1-benzofuran-4-amine Chemical class NC1=CC=CC2=C1C=CO2 OCZGGFAZAPGFMC-UHFFFAOYSA-N 0.000 title 1
KEJFADGISRFLFO-UHFFFAOYSA-N 1H-indazol-6-amine Chemical compound NC1=CC=C2C=NNC2=C1 KEJFADGISRFLFO-UHFFFAOYSA-N 0.000 title 1
239000002587 phosphodiesterase IV inhibitor Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
HFZZTHJMXZSGFP-UHFFFAOYSA-N 1-benzofuran-2-amine Chemical class C1=CC=C2OC(N)=CC2=C1 HFZZTHJMXZSGFP-UHFFFAOYSA-N 0.000 abstract 1
YDTDKKULPWTHRV-UHFFFAOYSA-N 1H-indazol-3-amine Chemical compound C1=CC=C2C(N)=NNC2=C1 YDTDKKULPWTHRV-UHFFFAOYSA-N 0.000 abstract 1
101100296720 Dictyostelium discoideum Pde4 gene Proteins 0.000 abstract 1
101100082610 Plasmodium falciparum (isolate 3D7) PDEdelta gene Proteins 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Addiction (AREA)
Psychology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Furan Compounds (AREA)

NO20050871A 2002-07-19 2005-02-18 6-amino-1H-indazol- og 4-aminobenzofuranforbindelser som fosfodiesterase 4-inhibitorer NO20050871L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US39672602P	2002-07-19	2002-07-19
PCT/US2003/022401 WO2004009557A1 (en)	2002-07-19	2003-07-18	6-amino-1h-indazole and 4-aminobenzofuran compounds as phosphodiesterase 4 inhibitors

Publications (1)

Publication Number	Publication Date
NO20050871L true NO20050871L (no)	2005-02-18

Family

ID=30770939

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20050871A NO20050871L (no)	2002-07-19	2005-02-18	6-amino-1H-indazol- og 4-aminobenzofuranforbindelser som fosfodiesterase 4-inhibitorer

Country Status (19)

Country	Link
US (2)	US7655802B2 (ja)
EP (1)	EP1549619B1 (ja)
JP (1)	JP2006502995A (ja)
CN (2)	CN100381425C (ja)
AT (1)	ATE421505T1 (ja)
AU (2)	AU2003256601B2 (ja)
BR (1)	BR0313000A (ja)
CA (1)	CA2492911A1 (ja)
CO (1)	CO5680420A2 (ja)
DE (1)	DE60325984D1 (ja)
ES (1)	ES2323688T3 (ja)
HR (1)	HRP20050082A2 (ja)
IL (1)	IL166164A0 (ja)
MX (1)	MXPA05000825A (ja)
NO (1)	NO20050871L (ja)
NZ (1)	NZ537725A (ja)
RU (1)	RU2354648C2 (ja)
WO (1)	WO2004009557A1 (ja)
ZA (1)	ZA200500436B (ja)

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2003
- 2003-07-18 RU RU2005104820/04A patent/RU2354648C2/ru not_active IP Right Cessation
- 2003-07-18 DE DE60325984T patent/DE60325984D1/de not_active Expired - Fee Related
- 2003-07-18 AT AT03765684T patent/ATE421505T1/de not_active IP Right Cessation
- 2003-07-18 CN CNB03817233XA patent/CN100381425C/zh not_active Expired - Fee Related
- 2003-07-18 AU AU2003256601A patent/AU2003256601B2/en not_active Ceased
- 2003-07-18 MX MXPA05000825A patent/MXPA05000825A/es active IP Right Grant
- 2003-07-18 JP JP2004523528A patent/JP2006502995A/ja active Pending
- 2003-07-18 CN CNA2008101082889A patent/CN101423497A/zh active Pending
- 2003-07-18 HR HR20050082A patent/HRP20050082A2/xx not_active Application Discontinuation
- 2003-07-18 ES ES03765684T patent/ES2323688T3/es not_active Expired - Lifetime
- 2003-07-18 CA CA002492911A patent/CA2492911A1/en not_active Abandoned
- 2003-07-18 NZ NZ537725A patent/NZ537725A/en unknown
- 2003-07-18 EP EP03765684A patent/EP1549619B1/en not_active Expired - Lifetime
- 2003-07-18 BR BR0313000-2A patent/BR0313000A/pt not_active IP Right Cessation
- 2003-07-18 WO PCT/US2003/022401 patent/WO2004009557A1/en not_active Ceased
2005
- 2005-01-05 IL IL16616405A patent/IL166164A0/xx unknown
- 2005-01-17 ZA ZA200500436A patent/ZA200500436B/xx unknown
- 2005-01-18 CO CO05003399A patent/CO5680420A2/es not_active Application Discontinuation
- 2005-02-18 NO NO20050871A patent/NO20050871L/no not_active Application Discontinuation
2006
- 2006-12-21 US US11/642,592 patent/US7655802B2/en not_active Expired - Fee Related
2009
- 2009-12-17 US US12/640,607 patent/US20100093806A1/en not_active Abandoned
2010
- 2010-01-21 AU AU2010200233A patent/AU2010200233A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HK1081194A1 (en)	2006-05-12
NZ537725A (en)	2006-08-31
US7655802B2 (en)	2010-02-02
CN100381425C (zh)	2008-04-16
AU2003256601B2 (en)	2009-10-29
CA2492911A1 (en)	2004-01-29
CN1668602A (zh)	2005-09-14
ZA200500436B (en)	2006-07-26
EP1549619B1 (en)	2009-01-21
ATE421505T1 (de)	2009-02-15
MXPA05000825A (es)	2005-08-29
AU2010200233A1 (en)	2010-02-11
CO5680420A2 (es)	2006-09-29
IL166164A0 (en)	2006-01-15
US20100093806A1 (en)	2010-04-15
HRP20050082A2 (en)	2005-06-30
JP2006502995A (ja)	2006-01-26
DE60325984D1 (de)	2009-03-12
RU2005104820A (ru)	2005-10-10
BR0313000A (pt)	2005-07-12
CN101423497A (zh)	2009-05-06
AU2003256601A1 (en)	2004-02-09
ES2323688T3 (es)	2009-07-23
EP1549619A1 (en)	2005-07-06
WO2004009557A1 (en)	2004-01-29
RU2354648C2 (ru)	2009-05-10
US20070123570A1 (en)	2007-05-31

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2011-02-28	FC2A	Withdrawal, rejection or dismissal of laid open patent application

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