NO20053595L - Escitalopramdibromid samt fremgangsmate ved fremstilling derav. - Google Patents

Escitalopramdibromid samt fremgangsmate ved fremstilling derav.

Info

Publication number: NO20053595L
Authority: NO; Norway
Prior art keywords: escitalopram; dibromide; citalopram; hydrobromide; processes
Prior art date: 2002-12-23

Application number

NO20053595A

Other languages

English (en)

Norwegian (no)

Inventor

Hans Petersen

Peter Ellegaard

Robert Dancer

Lawrence Martel

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-23

Filing date

2005-07-25

Publication date

2005-09-05

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32668635&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20053595(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-07-25 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2005-09-05 Publication of NO20053595L publication Critical patent/NO20053595L/no

Links

WSEQXVZVJXJVFP-FQEVSTJZSA-N escitalopram Chemical compound C1([C@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-FQEVSTJZSA-N 0.000 title abstract 2
229960004341 escitalopram Drugs 0.000 title abstract 2
CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 1
229960001653 citalopram Drugs 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Addiction (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Nutrition Science (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

NO20053595A 2002-12-23 2005-07-25 Escitalopramdibromid samt fremgangsmate ved fremstilling derav. NO20053595L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA200202005		2002-12-23
PCT/DK2003/000902 WO2004056791A1 (en)	2002-12-23	2003-12-18	Escitalopram hydrobromide and a method for the preparation thereof

Publications (1)

Publication Number	Publication Date
NO20053595L true NO20053595L (no)	2005-09-05

Family

ID=32668635

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20053595A NO20053595L (no)	2002-12-23	2005-07-25	Escitalopramdibromid samt fremgangsmate ved fremstilling derav.

Country Status (32)

Country	Link
US (1)	US20040167209A1 (sr)
EP (1)	EP1578738B1 (sr)
JP (2)	JP4658613B2 (sr)
KR (1)	KR20050086933A (sr)
CN (1)	CN100349885C (sr)
AR (1)	AR042652A1 (sr)
AT (1)	ATE388947T1 (sr)
AU (1)	AU2003287919B2 (sr)
BR (1)	BR0317623A (sr)
CA (1)	CA2511142A1 (sr)
CY (1)	CY1107451T1 (sr)
DE (1)	DE60319739T2 (sr)
DK (1)	DK1578738T3 (sr)
EA (1)	EA013116B1 (sr)
EG (1)	EG24729A (sr)
ES (1)	ES2298595T3 (sr)
IL (1)	IL169125A0 (sr)
IS (1)	IS2654B (sr)
ME (1)	MEP5808A (sr)
MX (1)	MXPA05005772A (sr)
MY (1)	MY135468A (sr)
NO (1)	NO20053595L (sr)
NZ (1)	NZ540281A (sr)
PE (1)	PE20040924A1 (sr)
PL (1)	PL378275A1 (sr)
PT (1)	PT1578738E (sr)
RS (1)	RS51092B (sr)
TW (1)	TW200501943A (sr)
UA (1)	UA80170C2 (sr)
UY (1)	UY28148A1 (sr)
WO (1)	WO2004056791A1 (sr)
ZA (1)	ZA200504109B (sr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050137255A1 (en) *	2002-12-23	2005-06-23	H. Lundbeck A/S	Crystalline escitalopram hydrobromide and methods for preparing the same
MEP5808A (xx) *	2002-12-23	2010-02-10	Lundbeck & Co As H	Ecitalopram bromhidrat i postupak za njegovo pripremanje
NZ549100A (en) *	2004-03-05	2010-02-26	Lundbeck & Co As H	Crystalline composition containing escitalopram oxalate
US7834201B2 (en)	2005-06-22	2010-11-16	H. Lundbeck A/S	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI358407B (en)	2005-06-22	2012-02-21	Lundbeck & Co As H	Crystalline base of escitalopram and orodispersibl
EA200801080A1 (ru) *	2005-10-14	2009-02-27	Х. Лундбекк А/С	Стабильные фармацевтические лекарственные формы, содержащие эсциталопрам и бупропион
CA2625835A1 (en) *	2005-10-14	2007-05-10	Forest Laboratories, Inc.	Methods of treating central nervous system disorders with a low dose combination of escitalopram and bupropion
TW200812993A (en) *	2006-05-02	2008-03-16	Lundbeck & Co As H	New uses of escitalopram
US8030303B2 (en)	2006-07-11	2011-10-04	Mitsubishi Tanabe Pharma Corporation	Salt of morpholine compound
WO2008059514A2 (en) *	2006-07-31	2008-05-22	Cadila Healthcare Limited	Process for preparing escitalopram
FR3006594A1 (fr) *	2013-06-11	2014-12-12	Sorin Crm Sas	Microsonde implantable de detection/stimulation incorporant un agent anti-inflammatoire
CN108976188B (zh) *	2017-06-05	2022-12-06	上海奥博生物医药股份有限公司	一种艾司西酞普兰双羟萘酸盐新的制备方法
US11390597B2 (en) *	2017-10-09	2022-07-19	Mark Hasleton	Salt and solid state forms of escitalopram
EP4277661A1 (en)	2021-01-18	2023-11-22	Anton Frenkel	Pharmaceutical dosage form

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US34712A (en) *		1862-03-18		James h
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en) *	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en) *	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
ES2189502T3 (es) *	1998-10-20	2003-07-01	Lundbeck & Co As H	Metodo para la prevencion de citalopram.
AR021155A1 (es) *	1999-07-08	2002-06-12	Lundbeck & Co As H	Tratamiento de desordenes neuroticos
DK1298124T3 (da) *	1999-10-25	2007-07-09	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
US6977306B2 (en) *	2000-05-02	2005-12-20	Sumitomo Chemical Company, Limited	Citalopram hydrobromide crystal and method for crystallization thereof
JP2002020379A (ja) *	2000-05-02	2002-01-23	Sumika Fine Chemicals Co Ltd	シタロプラム臭化水素酸塩の結晶およびその結晶化方法
CA2353693C (en) *	2000-08-10	2003-07-22	H. Lundbeck A/S	Pharmaceutical composition containing citalopram
ES2289016T3 (es) *	2000-12-04	2008-02-01	Westfalia Separator Ag	Procedimiento para la obtencion de esteres de acidos grasos.
CZ20033267A3 (en) *	2001-05-01	2004-06-16	H. Lundbeck A/S	The use of enantiomeric pure escitalopram
AR034612A1 (es) *	2001-06-25	2004-03-03	Lundbeck & Co As H	Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
MEP5808A (xx) *	2002-12-23	2010-02-10	Lundbeck & Co As H	Ecitalopram bromhidrat i postupak za njegovo pripremanje
US20050174782A1 (en) *	2003-03-25	2005-08-11	Chapman Leonard T.	Flashlight

2003
- 2003-12-18 ME MEP-58/08A patent/MEP5808A/xx unknown
- 2003-12-18 UA UAA200506077A patent/UA80170C2/uk unknown
- 2003-12-18 CA CA002511142A patent/CA2511142A1/en not_active Abandoned
- 2003-12-18 EP EP03779759A patent/EP1578738B1/en not_active Expired - Lifetime
- 2003-12-18 AU AU2003287919A patent/AU2003287919B2/en not_active Ceased
- 2003-12-18 NZ NZ540281A patent/NZ540281A/en not_active Application Discontinuation
- 2003-12-18 ES ES03779759T patent/ES2298595T3/es not_active Expired - Lifetime
- 2003-12-18 BR BR0317623-1A patent/BR0317623A/pt not_active IP Right Cessation
- 2003-12-18 JP JP2004561083A patent/JP4658613B2/ja not_active Expired - Lifetime
- 2003-12-18 DK DK03779759T patent/DK1578738T3/da active
- 2003-12-18 KR KR1020057011704A patent/KR20050086933A/ko not_active Ceased
- 2003-12-18 PL PL378275A patent/PL378275A1/pl not_active Application Discontinuation
- 2003-12-18 DE DE60319739T patent/DE60319739T2/de not_active Expired - Lifetime
- 2003-12-18 WO PCT/DK2003/000902 patent/WO2004056791A1/en not_active Ceased
- 2003-12-18 AT AT03779759T patent/ATE388947T1/de not_active IP Right Cessation
- 2003-12-18 EA EA200501046A patent/EA013116B1/ru not_active IP Right Cessation
- 2003-12-18 CN CNB2003801063775A patent/CN100349885C/zh not_active Expired - Fee Related
- 2003-12-18 PT PT03779759T patent/PT1578738E/pt unknown
- 2003-12-18 MX MXPA05005772A patent/MXPA05005772A/es active IP Right Grant
- 2003-12-18 RS YUP-2005/0487A patent/RS51092B/sr unknown
- 2003-12-22 AR ARP030104777A patent/AR042652A1/es unknown
- 2003-12-22 TW TW092136380A patent/TW200501943A/zh unknown
- 2003-12-22 MY MYPI20034949A patent/MY135468A/en unknown
- 2003-12-23 US US10/746,913 patent/US20040167209A1/en not_active Abandoned
- 2003-12-23 UY UY28148A patent/UY28148A1/es not_active Application Discontinuation
2004
- 2004-01-05 PE PE2004000013A patent/PE20040924A1/es not_active Application Discontinuation
2005
- 2005-05-17 IS IS7848A patent/IS2654B/is unknown
- 2005-05-20 ZA ZA200504109A patent/ZA200504109B/en unknown
- 2005-06-09 IL IL169125A patent/IL169125A0/en unknown
- 2005-06-22 EG EGNA2005000345 patent/EG24729A/xx active
- 2005-07-25 NO NO20053595A patent/NO20053595L/no not_active Application Discontinuation
2008
- 2008-05-02 CY CY20081100470T patent/CY1107451T1/el unknown
2010
- 2010-10-20 JP JP2010235287A patent/JP2011037893A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
EG24729A (en)	2010-06-21
IS2654B (is)	2010-08-15
IL169125A0 (en)	2009-02-11
RS51092B (sr)	2010-10-31
ES2298595T3 (es)	2008-05-16
EP1578738A1 (en)	2005-09-28
ATE388947T1 (de)	2008-03-15
PL378275A1 (pl)	2006-03-20
JP4658613B2 (ja)	2011-03-23
DE60319739T2 (de)	2008-07-17
AU2003287919A1 (en)	2004-07-14
ZA200504109B (en)	2006-08-30
HK1087708A1 (en)	2006-10-20
BR0317623A (pt)	2005-11-29
CA2511142A1 (en)	2004-07-08
RS20050487A (sr)	2007-06-04
IS7848A (is)	2005-05-17
DK1578738T3 (da)	2008-06-30
DE60319739D1 (de)	2008-04-24
EA013116B1 (ru)	2010-02-26
TW200501943A (en)	2005-01-16
MY135468A (en)	2008-04-30
EA200501046A1 (ru)	2005-12-29
US20040167209A1 (en)	2004-08-26
EP1578738B1 (en)	2008-03-12
MXPA05005772A (es)	2005-08-16
UA80170C2 (en)	2007-08-27
UY28148A1 (es)	2004-09-30
NZ540281A (en)	2008-07-31
AR042652A1 (es)	2005-06-29
PE20040924A1 (es)	2004-12-11
MEP5808A (xx)	2010-02-10
AU2003287919B2 (en)	2009-11-12
CN1726202A (zh)	2006-01-25
PT1578738E (pt)	2008-04-11
KR20050086933A (ko)	2005-08-30
JP2011037893A (ja)	2011-02-24
JP2006514952A (ja)	2006-05-18
WO2004056791A1 (en)	2004-07-08
CY1107451T1 (el)	2012-12-19
CN100349885C (zh)	2007-11-21

Legal Events

Date	Code	Title	Description
2008-07-14	CREP	Change of representative	Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104
2011-07-25	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
SG130189A1 (en)	2007-03-20	Substituted indole-o-glucosides
CL2004001174A1 (es)	2005-05-06	Composicion farmaceutica que comprende: 1-(4-fluorofenil)-3(r)-[3-(4-fluorofenil)-3(s)-hidroxipropil]-4(s)-(4-hidroxifenil)-2-acetidinona (ezetimiba) y excipientes; y su uso en el tratamiento y/o prevencion de aterosclerosis, hipercolesterolemia, dia
UA86042C2 (en)	2009-03-25	Substituted indazole-o-glucosides
CY1107451T1 (el)	2012-12-19	Υδροβρωμικον escitalopram και μεθοδος δια την παρασκευη αυτου
DE50015623D1 (de)	2009-05-28	Kovalent verbrückte insulindimere
SE0100901D0 (sv)	2001-03-15	New composition
DE60022692D1 (de)	2005-10-20	(S,S)-Reboxetin zur Behandlung von Migränekopfschmerzen
EA200601555A1 (ru)	2007-02-27	Замещенные индазол-о-глюкозиды
BRPI0414599A (pt)	2006-11-07	pirrol-indóis substituìdos
NO20050091L (no)	2005-04-06	Fremgangsmater for fremstilling av fibrinogen
DK1465641T3 (da)	2007-11-19	Lægemidler indeholdende deuterium til behandling af sukkersyge
HU229456B1 (en)	2013-12-30	Aminoalkylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same
NO20041200L (no)	2004-03-23	Fremgangsmate for fremstilling av citalopram.
GB0216002D0 (en)	2002-08-21	Process and composition
NO20031648D0 (no)	2003-04-10	Farmasöytiske lösninger av modafinilforbindelser
MXPA03007635A (es)	2003-12-04	P-tienilbencilamidas que sirven como agonistas de receptores para angiotensina-(1-7), metodo para su produccion, su uso y preparaciones farmaceuticas que las contienen.
WO2004099388A3 (en)	2007-11-22	Cbl-b polypeptides, complexes and related methods
NO20026128L (no)	2003-06-23	Gelformet drivstoff, fremgangsmåte for dets fremstilling og dets anvendelse
NO331195B1 (no)	2011-10-31	Fremgangsmate for fremstilling av halogen-substituerte monosulfider og deres hydroksymonosulfid-evkivalenter som mellomprodukter.
NO20033318D0 (no)	2003-07-23	2H-1-benzopyranderivater, fremgangsmåte ved fremstilling samt farmasöytiskesammensetninger derav
JP2004500380A5 (sr)	2006-01-05
MY149864A (en)	2013-10-31	Flavouring-containing pharmaceutical formulations with improved pharmaceutical properties
TR200402030T4 (tr)	2004-09-21	İkame edilen I-aminobutan-3-ol-türevleri
HRP20051005A2 (en)	2006-09-30	Process for the preparation of nonpeptide substituted spirobenzoazepine derivatives
NO20031108D0 (no)	2003-03-11	Farmasöytisk preparat for behandling av hodepine, og fremgangsmåte for fremstilling av preparatet