NO20060231L - Difenylureaderivater og deres anvendelse som kloridkanalblokkere - Google Patents
Difenylureaderivater og deres anvendelse som kloridkanalblokkereInfo
- Publication number
- NO20060231L NO20060231L NO20060231A NO20060231A NO20060231L NO 20060231 L NO20060231 L NO 20060231L NO 20060231 A NO20060231 A NO 20060231A NO 20060231 A NO20060231 A NO 20060231A NO 20060231 L NO20060231 L NO 20060231L
- Authority
- NO
- Norway
- Prior art keywords
- channel blockers
- chloride channel
- diphenylurea derivatives
- derivatives
- diphenylurea
- Prior art date
Links
- GWEHVDNNLFDJLR-UHFFFAOYSA-N 1,3-diphenylurea Chemical class C=1C=CC=CC=1NC(=O)NC1=CC=CC=C1 GWEHVDNNLFDJLR-UHFFFAOYSA-N 0.000 title abstract 2
- 108010062745 Chloride Channels Proteins 0.000 title abstract 2
- 102000011045 Chloride Channels Human genes 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200300898 | 2003-06-17 | ||
| PCT/EP2004/051111 WO2004111017A1 (en) | 2003-06-17 | 2004-06-15 | Diphenylurea derivatives and their use as chloride channel blockers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20060231L true NO20060231L (no) | 2006-01-16 |
Family
ID=33547538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20060231A NO20060231L (no) | 2003-06-17 | 2006-01-16 | Difenylureaderivater og deres anvendelse som kloridkanalblokkere |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7691891B2 (de) |
| EP (1) | EP1638948B1 (de) |
| JP (1) | JP2006527735A (de) |
| KR (1) | KR20060059901A (de) |
| CN (1) | CN1805942B (de) |
| AT (1) | ATE411301T1 (de) |
| AU (1) | AU2004247429B2 (de) |
| BR (1) | BRPI0410576A (de) |
| CA (1) | CA2529806A1 (de) |
| DE (1) | DE602004017175D1 (de) |
| DK (1) | DK1638948T3 (de) |
| IS (1) | IS8211A (de) |
| MX (1) | MXPA05013269A (de) |
| NO (1) | NO20060231L (de) |
| NZ (1) | NZ543595A (de) |
| RU (1) | RU2350607C2 (de) |
| UA (1) | UA81664C2 (de) |
| WO (1) | WO2004111017A1 (de) |
| ZA (1) | ZA200508828B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101287456A (zh) * | 2004-12-17 | 2008-10-15 | 神经研究公司 | 用作钾通道激活剂的二苯基脲衍生物 |
| MX2008011409A (es) * | 2006-03-14 | 2008-09-22 | Neurosearch As | Derivados de difenilurea y su uso como bloqueadores de canal de cloruro o moduladores del canal bkca. |
| WO2009068557A1 (en) * | 2007-11-28 | 2009-06-04 | Neurosearch A/S | Novel phenyl-acetamide and phenyl-propionamide derivatives useful as potassium channel modulators |
| US9834537B2 (en) | 2013-11-27 | 2017-12-05 | Korea Institute Of Science And Technology | Compounds as chloride channel blocking agent |
| EP3622953B1 (de) | 2016-05-17 | 2021-03-17 | Scandion Oncology A/S | Kombinationsbehandlung für krebs |
| CN117229258B (zh) * | 2022-06-07 | 2024-07-19 | 杭州壹瑞医药科技有限公司 | N-四唑基芳基脲类衍生物及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2255858C (en) * | 1996-05-24 | 2007-09-11 | Neurosearch A/S | Phenyl derivatives containing an acidic group, their preparation and their use as chloride channel blockers |
| US6696475B2 (en) * | 1997-04-22 | 2004-02-24 | Neurosearch A/S | Substituted phenyl derivatives, their preparation and use |
| CZ295822B6 (cs) * | 1997-04-22 | 2005-11-16 | Neurosearch A/S | Substituované fenylderiváty, způsob jejich přípravy a použití a farmaceutické přípravky s jejich obsahem |
| WO2000020378A1 (en) | 1998-10-02 | 2000-04-13 | Neurosearch A/S | Diaminocyclobutene-3,4-dione derivatives, their preparation and use |
| CN1263733C (zh) | 1998-10-22 | 2006-07-12 | 神经研究公司 | 取代苯基衍生物,它们的制备和用途 |
| WO2002039987A2 (en) * | 2000-11-14 | 2002-05-23 | Neurosearch A/S | Use of malaria parasite anion channel blockers for treating malaria |
| WO2003000245A1 (en) * | 2001-06-22 | 2003-01-03 | Poseidon Pharmaceuticals A/S | Compounds for use in disorders associated with mast cell or basophil activity |
| JP2005537336A (ja) * | 2002-08-01 | 2005-12-08 | ニューロサーチ、アクティーゼルスカブ | 抗血管新生治療に応答する疾患の治療に有用な化合物 |
| EP1537075B1 (de) * | 2002-09-05 | 2009-07-01 | Neurosearch A/S | Diarylharnstoffderivate und deren verwendung als chloridkanalblocker |
| CN101287456A (zh) * | 2004-12-17 | 2008-10-15 | 神经研究公司 | 用作钾通道激活剂的二苯基脲衍生物 |
-
2004
- 2004-06-15 ZA ZA200508828A patent/ZA200508828B/en unknown
- 2004-06-15 AT AT04741799T patent/ATE411301T1/de not_active IP Right Cessation
- 2004-06-15 NZ NZ543595A patent/NZ543595A/en unknown
- 2004-06-15 CN CN2004800168685A patent/CN1805942B/zh not_active Expired - Fee Related
- 2004-06-15 UA UAA200510477A patent/UA81664C2/ru unknown
- 2004-06-15 EP EP04741799A patent/EP1638948B1/de not_active Expired - Lifetime
- 2004-06-15 DK DK04741799T patent/DK1638948T3/da active
- 2004-06-15 WO PCT/EP2004/051111 patent/WO2004111017A1/en not_active Ceased
- 2004-06-15 DE DE602004017175T patent/DE602004017175D1/de not_active Expired - Lifetime
- 2004-06-15 MX MXPA05013269A patent/MXPA05013269A/es active IP Right Grant
- 2004-06-15 BR BRPI0410576-1A patent/BRPI0410576A/pt not_active IP Right Cessation
- 2004-06-15 JP JP2006516151A patent/JP2006527735A/ja active Pending
- 2004-06-15 US US10/561,189 patent/US7691891B2/en not_active Expired - Fee Related
- 2004-06-15 AU AU2004247429A patent/AU2004247429B2/en not_active Ceased
- 2004-06-15 KR KR1020057024088A patent/KR20060059901A/ko not_active Ceased
- 2004-06-15 CA CA002529806A patent/CA2529806A1/en not_active Abandoned
- 2004-06-15 RU RU2005136532/04A patent/RU2350607C2/ru not_active IP Right Cessation
-
2005
- 2005-12-30 IS IS8211A patent/IS8211A/is unknown
-
2006
- 2006-01-16 NO NO20060231A patent/NO20060231L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE411301T1 (de) | 2008-10-15 |
| RU2005136532A (ru) | 2006-07-27 |
| US20060178413A1 (en) | 2006-08-10 |
| ZA200508828B (en) | 2008-01-30 |
| DE602004017175D1 (de) | 2008-11-27 |
| RU2350607C2 (ru) | 2009-03-27 |
| EP1638948B1 (de) | 2008-10-15 |
| US7691891B2 (en) | 2010-04-06 |
| EP1638948A1 (de) | 2006-03-29 |
| AU2004247429B2 (en) | 2010-01-28 |
| DK1638948T3 (da) | 2009-02-02 |
| CN1805942B (zh) | 2010-06-02 |
| CA2529806A1 (en) | 2004-12-23 |
| UA81664C2 (ru) | 2008-01-25 |
| AU2004247429A1 (en) | 2004-12-23 |
| JP2006527735A (ja) | 2006-12-07 |
| IS8211A (is) | 2005-12-30 |
| HK1091816A1 (zh) | 2007-01-26 |
| BRPI0410576A (pt) | 2006-06-20 |
| WO2004111017A1 (en) | 2004-12-23 |
| KR20060059901A (ko) | 2006-06-02 |
| NZ543595A (en) | 2009-01-31 |
| MXPA05013269A (es) | 2006-03-17 |
| CN1805942A (zh) | 2006-07-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20073791L (no) | Pyrazolylaminopyridinderivater anvendbare som kinaseinhibitorer | |
| NO20064763L (no) | Forbindelser og fremgangsmater for behandling av dyslipidemi | |
| EA201200669A1 (ru) | ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα | |
| NO20064976L (no) | Azanidoler som er nyttige som inhibitorer av rock og andre proteinkinaser | |
| NO20054905L (no) | 2-acylamino-4-fenyltiazolderivater, fremgangsmate for deres fremstilling og anvendelse av de samme som i terapeutika | |
| EA200800760A1 (ru) | ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα | |
| NO20090628L (no) | Pyridizinon derivativater | |
| NO20071549L (no) | Nye benzofuserte heteroalrylsulfamidderivater, anvendelige som anti-krampemidler | |
| EA200702674A1 (ru) | Способ лечения атеросклероза, дислипидемий и связанных с ними состояний и фармацевтические композиции | |
| ATE484508T1 (de) | Furylverbindungen | |
| NO20062649L (no) | Biarylsulfonamider og metoder for anvendelse av disse | |
| BRPI0716069A2 (pt) | composto, composiÇço farmacÊutica, e, mÉtodo para tratar um distérbio | |
| NO20054083L (no) | Nye sammenkoblede triazoloner og deres anvendelse | |
| NO20080394L (no) | N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav | |
| EA201070009A1 (ru) | Производные 7-алкинил-1,8-нафтиридонов, их получение и их применение в терапии | |
| NO20062021L (no) | Omleirede pentanoler, fremgangsmpte for fremstilling av dette, og deres anvendelse som antiflogistika | |
| NO20054340L (no) | Nye sammenkoplede heterocykler og deres anvendelse | |
| NO20060360L (no) | Nye 8-azabisyklo [3.2.1] oktanderivater og deres anvendelse som monoaminneurotransmittergjenopptaksinhibitorer | |
| NO20065320L (no) | Imidazolderivater anvendt som tafiainhibitorer | |
| NO20083201L (no) | Nye fenantridinderivater som bradykininantagonister | |
| NO20073652L (no) | Enantiomerer av 3-heteroaryl-8H-8-azabisyklo(3.2.1)okt-2-en og deres anvendelse som monoaminnevrotransmitter-gjenopptaksinhibitorer | |
| DK1606288T3 (da) | Benzensulfonamidderivater, fremgangsmåde til fremstilling deraf og deres anvendelse til behandling af smerte | |
| DE60329326D1 (de) | Tace inhibitoren | |
| NO20084279L (no) | Difenylureaderivater og deres anvendelse som kloridkanalblokkere eller BKCa-kanalmodulatorer | |
| EA200800374A1 (ru) | 1,4-дигидропиридин-конденсированные гетероциклы, способы их получения, применение и содержащие их композиции |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |