NO20060319L - 3,5-disubstituerte indazolforbindelser, farmasoytiske blandinger og fremgangsmater for a mediere eller inhibere celleproliferasjon - Google Patents

3,5-disubstituerte indazolforbindelser, farmasoytiske blandinger og fremgangsmater for a mediere eller inhibere celleproliferasjon

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Publication number
NO20060319L
NO20060319L NO20060319A NO20060319A NO20060319L NO 20060319 L NO20060319 L NO 20060319L NO 20060319 A NO20060319 A NO 20060319A NO 20060319 A NO20060319 A NO 20060319A NO 20060319 L NO20060319 L NO 20060319L
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Norway
Prior art keywords
compounds
cell proliferation
mediate
methods
inhibit cell
Prior art date
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NO20060319A
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English (en)
Inventor
Susan Elizabeth Kephart
Indrawan James Mcalpine
Siegfried Heinz Reich
Original Assignee
Pfizer
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Application filed by Pfizer filed Critical Pfizer
Publication of NO20060319L publication Critical patent/NO20060319L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

3,5-substituert indazolforbindelser som modulerer og/eller inhiberer celleproliferasjon, så som aktiviteten til proteinkinaser er beskrevet. Disse forbindelsene og farmasøytiske preparater inneholdende dem kan mediere CDK-avhengig sykdommer til å modulere og/eller inhiberer uønsket celleproliferasjon. Oppfinnelsen angår også terapeutisk eller forebyggende anvendelse av farmasøytiske preparater inneholdende slike forbindelser samt fremgangsmåter for behandling av kreft så vel som andre sykdomstilstander forbundet med uønsket angiogenese og/eller cellulær proliferasjon, så som diabetisk retinopati, neovaskulær glaukom, revmatoid artritt og psoriasis, ved administrering av effektive mengder av slike forbindelser.
NO20060319A 2003-07-30 2006-01-20 3,5-disubstituerte indazolforbindelser, farmasoytiske blandinger og fremgangsmater for a mediere eller inhibere celleproliferasjon NO20060319L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49147403P 2003-07-30 2003-07-30
US49207303P 2003-07-31 2003-07-31
PCT/IB2004/002441 WO2005009997A1 (en) 2003-07-30 2004-07-19 3,5 disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation

Publications (1)

Publication Number Publication Date
NO20060319L true NO20060319L (no) 2006-02-24

Family

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Family Applications (1)

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NO20060319A NO20060319L (no) 2003-07-30 2006-01-20 3,5-disubstituerte indazolforbindelser, farmasoytiske blandinger og fremgangsmater for a mediere eller inhibere celleproliferasjon

Country Status (24)

Country Link
US (2) US7008953B2 (no)
EP (1) EP1658284A1 (no)
JP (1) JP3920914B2 (no)
KR (1) KR20060030914A (no)
AR (1) AR045143A1 (no)
AU (1) AU2004259531A1 (no)
BR (1) BRPI0413051A (no)
CA (1) CA2532908A1 (no)
CO (1) CO5650247A2 (no)
EA (1) EA200600123A1 (no)
EC (1) ECSP066335A (no)
IL (1) IL172924A0 (no)
IS (1) IS8214A (no)
MA (1) MA27937A1 (no)
MX (1) MXPA06001193A (no)
NL (1) NL1026761C2 (no)
NO (1) NO20060319L (no)
OA (1) OA13196A (no)
PA (1) PA8608201A1 (no)
PE (1) PE20050330A1 (no)
TN (1) TNSN06038A1 (no)
TW (1) TW200521124A (no)
UY (1) UY28442A1 (no)
WO (1) WO2005009997A1 (no)

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US7008953B2 (en) 2006-03-07
NL1026761C2 (nl) 2005-10-18
US20060142345A1 (en) 2006-06-29
IS8214A (is) 2005-12-30
JP2007500183A (ja) 2007-01-11
TW200521124A (en) 2005-07-01
BRPI0413051A (pt) 2006-10-17
US20050026960A1 (en) 2005-02-03
NL1026761A1 (nl) 2005-02-01
MA27937A1 (fr) 2006-06-01
EP1658284A1 (en) 2006-05-24
PA8608201A1 (es) 2005-03-03
MXPA06001193A (es) 2006-04-11
JP3920914B2 (ja) 2007-05-30
AU2004259531A1 (en) 2005-02-03
ECSP066335A (es) 2006-07-28
UY28442A1 (es) 2005-02-28
OA13196A (en) 2006-12-13
CA2532908A1 (en) 2005-02-03
AR045143A1 (es) 2005-10-19
WO2005009997A1 (en) 2005-02-03
EA200600123A1 (ru) 2006-06-30
PE20050330A1 (es) 2005-05-16
IL172924A0 (en) 2006-06-11

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