NO20062110L - Farmasoytiske formuleringer fremgangsmater og doseringsregimer for behandling og forebygging av akutte hjertesviktsyndromer. - Google Patents

Farmasoytiske formuleringer fremgangsmater og doseringsregimer for behandling og forebygging av akutte hjertesviktsyndromer.

Info

Publication number
NO20062110L
NO20062110L NO20062110A NO20062110A NO20062110L NO 20062110 L NO20062110 L NO 20062110L NO 20062110 A NO20062110 A NO 20062110A NO 20062110 A NO20062110 A NO 20062110A NO 20062110 L NO20062110 L NO 20062110L
Authority
NO
Norway
Prior art keywords
pharmaceutical formulations
prevention
treatment
heart failure
dosage regimens
Prior art date
Application number
NO20062110A
Other languages
English (en)
Other versions
NO339456B1 (no
Inventor
Charles Larry Bisgaier
Wendi Rodrigueza
Narendra D Lalwani
Daniel Hartman
Jan Johansson
Original Assignee
Esperion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esperion Therapeutics Inc filed Critical Esperion Therapeutics Inc
Publication of NO20062110L publication Critical patent/NO20062110L/no
Publication of NO339456B1 publication Critical patent/NO339456B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Oppfinnelsen tilveiebringer fremgangsmåter og formuleringer for å behandle og å forebygge akutte koronare syndromer. Fremgangsmåtene i den foreliggende oppfinnelsen tilveiebringer trygge og effektive doser av et apolipoprotein A-I Milano:fosfolipidkompleks for å redusere og å stabilisere aterosklerotiske plakk. Farmasøytiske formuleringer av Apo A-I Milano:fosfolipidkomplekser ble også tilveiebrakt.
NO20062110A 2003-10-20 2006-05-11 Apo A-IM:POPC-kompleks for anvendelse i en fremgangsmåte for å behandle akutte koronarsyndromer NO339456B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51311603P 2003-10-20 2003-10-20
US51701603P 2003-11-03 2003-11-03
US57112904P 2004-05-14 2004-05-14
PCT/US2004/034800 WO2005041866A2 (en) 2003-10-20 2004-10-19 Pharmaceutical formulations, methods and dosing regimens for the treatment and prevention of acute coronary syndromes

Publications (2)

Publication Number Publication Date
NO20062110L true NO20062110L (no) 2006-07-18
NO339456B1 NO339456B1 (no) 2016-12-12

Family

ID=34557347

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062110A NO339456B1 (no) 2003-10-20 2006-05-11 Apo A-IM:POPC-kompleks for anvendelse i en fremgangsmåte for å behandle akutte koronarsyndromer

Country Status (23)

Country Link
US (2) US7435717B2 (no)
EP (1) EP1677597B1 (no)
JP (1) JP2007509157A (no)
KR (3) KR20070110561A (no)
AR (1) AR046126A1 (no)
AU (2) AU2004284932A1 (no)
CA (1) CA2542726C (no)
CO (1) CO5690611A2 (no)
CR (1) CR8352A (no)
EA (1) EA010134B1 (no)
EC (1) ECSP066516A (no)
ES (1) ES2449719T3 (no)
GE (1) GEP20094601B (no)
IL (1) IL174301A (no)
MA (1) MA28102A1 (no)
MX (1) MXPA06004362A (no)
NO (1) NO339456B1 (no)
NZ (1) NZ545939A (no)
OA (1) OA13272A (no)
PA (1) PA8615301A1 (no)
PE (1) PE20050438A1 (no)
RS (1) RS20060273A (no)
WO (1) WO2005041866A2 (no)

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Also Published As

Publication number Publication date
NZ545939A (en) 2008-08-29
KR20060080227A (ko) 2006-07-07
EA200600548A1 (ru) 2006-10-27
NO339456B1 (no) 2016-12-12
EP1677597A4 (en) 2011-08-24
EP1677597A2 (en) 2006-07-12
AU2011202014B2 (en) 2012-06-14
WO2005041866A2 (en) 2005-05-12
RS20060273A (sr) 2008-09-29
KR20100101710A (ko) 2010-09-17
PE20050438A1 (es) 2005-06-14
PA8615301A1 (es) 2005-09-28
ECSP066516A (es) 2006-11-24
AU2011202014A1 (en) 2011-05-26
IL174301A0 (en) 2006-08-01
MXPA06004362A (es) 2006-09-04
MA28102A1 (fr) 2006-08-01
WO2005041866A3 (en) 2006-05-18
CR8352A (es) 2007-03-02
JP2007509157A (ja) 2007-04-12
KR20070110561A (ko) 2007-11-19
EP1677597B1 (en) 2014-01-08
ES2449719T3 (es) 2014-03-20
AU2004284932A1 (en) 2005-05-12
OA13272A (en) 2007-01-31
CA2542726C (en) 2012-05-15
CO5690611A2 (es) 2006-10-31
HK1093869A1 (en) 2007-03-16
EA010134B1 (ru) 2008-06-30
IL174301A (en) 2013-09-30
US20050142180A1 (en) 2005-06-30
US7435717B2 (en) 2008-10-14
CA2542726A1 (en) 2005-05-12
GEP20094601B (en) 2009-02-10
US20080293633A1 (en) 2008-11-27
AR046126A1 (es) 2005-11-23

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