NO20062300L - Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser - Google Patents

Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser

Info

Publication number
NO20062300L
NO20062300L NO20062300A NO20062300A NO20062300L NO 20062300 L NO20062300 L NO 20062300L NO 20062300 A NO20062300 A NO 20062300A NO 20062300 A NO20062300 A NO 20062300A NO 20062300 L NO20062300 L NO 20062300L
Authority
NO
Norway
Prior art keywords
treatment
reagents
methods
inflammatory disorders
compound
Prior art date
Application number
NO20062300A
Other languages
English (en)
Norwegian (no)
Inventor
Edward Roydon Jost-Price
Brendan Smith
Benjamin A Auspitz
Palaniyandi Manivasakam
Michael S Slavonic
Original Assignee
Combinatorx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Combinatorx Inc filed Critical Combinatorx Inc
Publication of NO20062300L publication Critical patent/NO20062300L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20062300A 2003-11-21 2006-05-22 Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser NO20062300L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52411703P 2003-11-21 2003-11-21
PCT/US2004/038512 WO2005051293A2 (fr) 2003-11-21 2004-11-17 Procedes et reactifs destines au traitement de troubles inflammatoires

Publications (1)

Publication Number Publication Date
NO20062300L true NO20062300L (no) 2006-08-21

Family

ID=34632866

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062300A NO20062300L (no) 2003-11-21 2006-05-22 Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser

Country Status (17)

Country Link
US (2) US7709495B2 (fr)
EP (1) EP1689390B1 (fr)
JP (1) JP2007512337A (fr)
KR (1) KR20060120208A (fr)
CN (1) CN1905870A (fr)
AT (1) ATE497763T1 (fr)
AU (1) AU2004292445B2 (fr)
BR (1) BRPI0416812A (fr)
CA (1) CA2546347A1 (fr)
DE (1) DE602004031356D1 (fr)
IL (1) IL175781A0 (fr)
NO (1) NO20062300L (fr)
NZ (1) NZ547389A (fr)
RU (1) RU2006121978A (fr)
SG (1) SG148198A1 (fr)
WO (1) WO2005051293A2 (fr)
ZA (1) ZA200604253B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004031356D1 (de) * 2003-11-21 2011-03-24 Zalicus Inc Verfahren und reagenzien zur behandlung von entzündlichen erkrankungen
JP4954085B2 (ja) 2004-12-06 2012-06-13 メディシノバ， インコーポレイテッド 神経障害性疼痛及びその関連する症状を治療するためのイブジラスト
CN101203214B (zh) * 2005-04-13 2012-11-21 艾升制药公司 用于治疗皮肤结缔组织疾病的β2-肾上腺素受体激动剂
BRPI0620225A2 (pt) * 2005-12-20 2011-11-01 Tika Läkemedel Ab métodos e sistemas para a distribuição de corticosteróides tendo um perfil farmacocinético aumentado
CA2640484A1 (fr) * 2006-01-26 2007-08-09 Combinatorx, Incorporated Methodes, compositions et necessaires pour traiter des troubles musculo-squelettiques et des symptomes qui y sont associes
WO2007142924A1 (fr) * 2006-05-31 2007-12-13 Avigen, Inc. Ibudilast destiné à inhiber l'activité du facteur inhibiteur de la migration des macrophages (mif)
RU2008152776A (ru) * 2006-06-06 2010-07-20 Эвиджен Инк. (Us) СОЕДИНЕНИЯ ЗАМЕЩЕННОГО ПИРАЗОЛО[1,5-a]ПИРИДИНА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
US7536799B2 (en) * 2007-06-07 2009-05-26 Keson Industries Chalk line apparatus with strategically located chalk fill opening
US20090005358A1 (en) * 2007-06-26 2009-01-01 Jan Lessem Compositions and methods for treating medical conditions
US8138201B2 (en) 2007-07-11 2012-03-20 Medicinova, Inc. Treatment of progressive neurodegenerative disease with ibudilast
RU2390334C1 (ru) * 2008-12-17 2010-05-27 Государственное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова Федерального агентства по здравоохранению и социальному развитию" Способ лечения рассеянного склероза
GB201305714D0 (en) * 2013-03-28 2013-05-15 Ucl Business Plc Method
RU2536274C1 (ru) * 2013-12-20 2014-12-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Тверская государственная медицинская академия" Министерства здравоохранения Российской Федерации Способ лечения бородавок
CN108033959A (zh) * 2018-01-29 2018-05-15 山东省药学科学院 一种异丁司特的化学合成方法
WO2019226515A1 (fr) * 2018-05-21 2019-11-28 The University Of North Carolina At Chapel Hill Procédés d'inhibition de signalisation neuro-immunitaire pro-inflammatoire et méthodes de traitement de troubles inflammatoires
CN113456618A (zh) * 2020-03-31 2021-10-01 天津金耀集团有限公司 一种复方双嘧达莫的吸入制剂及其制备方法
CA3174413A1 (fr) * 2020-04-06 2021-10-14 Yuichi Iwaki Procedes de reduction du taux plasmatique d'un facteur d'inhibition de la de migration des macrophages chez des patients soignes par l'idubilast
WO2022164948A1 (fr) * 2021-01-29 2022-08-04 Medicinova, Inc. Méthodes de traitement d'une exposition à des gaz chimiques
KR20240019687A (ko) * 2022-08-04 2024-02-14 국민대학교산학협력단 하이드록시기를 갖는 방향족 카르복실산, 이의 에스테르 화합물 또는 이들의 유도체를 포함하는 장내 미생물 균총 개선용 조성물
CN115414354A (zh) * 2022-08-29 2022-12-02 西南医科大学 花椒毒素在制备治疗血小板减少症药物中的应用
KR102900597B1 (ko) * 2022-12-09 2025-12-18 대한민국 Impdh 억제제를 포함하는 중증열성혈소판감소증후군 예방 또는 치료용 조성물

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US532248A (en) 1895-01-08 powell
JPS5229318B2 (fr) 1972-03-30 1977-08-01
US4097483A (en) 1974-11-01 1978-06-27 Kyorin Pharmaceutical Co., Ltd. Pyrazolo 1,5-a!pyridines
DE2907460A1 (de) 1978-03-07 1979-09-13 Sandoz Ag Neue resorbierbare galenische kompositionen
JPS59167590A (ja) 1983-03-14 1984-09-21 Kyorin Pharmaceut Co Ltd ピラゾロ〔１，５−ａ〕ピリジン誘導体、その製法及びそれを含有する治療剤
US4894366A (en) 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US5254562A (en) 1984-12-03 1993-10-19 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
JP2577049B2 (ja) 1987-06-04 1997-01-29 三共株式会社 シクロスポリン製剤
US4925849A (en) 1987-06-15 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutically useful pyrazolopyridines
JPH01153634A (ja) * 1987-12-10 1989-06-15 Kyorin Pharmaceut Co Ltd 吸入剤
US6007840A (en) 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US5342625A (en) 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US5208228A (en) 1989-11-13 1993-05-04 Merck & Co., Inc. Aminomacrolides and derivatives having immunosuppressive activity
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5143918A (en) 1990-10-11 1992-09-01 Merck & Co., Inc. Halomacrolides and derivatives having immunosuppressive activity
US5626863A (en) 1992-02-28 1997-05-06 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5262533A (en) 1991-05-13 1993-11-16 Merck & Co., Inc. Amino O-aryl macrolides having immunosuppressive activity
US5162334A (en) 1991-05-13 1992-11-10 Merck & Co., Inc. Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity
US5250678A (en) 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5189042A (en) 1991-08-22 1993-02-23 Merck & Co. Inc. Fluoromacrolides having immunosuppressive activity
US5208241A (en) 1991-09-09 1993-05-04 Merck & Co., Inc. N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity
EP0625045A4 (fr) * 1992-02-07 1995-01-18 Albert M Kligman Procedes de traitement de dermatoses inflammatoires.
US5284840A (en) 1992-06-12 1994-02-08 Merck & Co., Inc. Alkylidene macrolides having immunosuppressive activity
US6022852A (en) 1993-10-22 2000-02-08 Hexal Ag Pharmaceutical composition containing cyclosporin A
US5693648A (en) 1994-09-30 1997-12-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
US5696130A (en) 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Tricyclic steroid receptor modulator compounds and methods
ES2247604T3 (es) * 1995-06-12 2006-03-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de ciclooxigenasa-2 y un inhibidor de 5-lipoxigenasa.
JPH0920663A (ja) * 1995-07-07 1997-01-21 Teikoku Seiyaku Co Ltd イブジラストを含有する徐放性細粒剤およびその製法
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
JPH11222425A (ja) * 1997-10-27 1999-08-17 Ss Pharmaceut Co Ltd 関節疾患治療用関節内投与製剤
US6372779B1 (en) 1997-12-29 2002-04-16 Ortho Pharmaceutical Corporation Anti-inflammatory compounds
US5900249A (en) * 1998-02-09 1999-05-04 Smith; David J. Multicomponent pain relief topical medication
US6506766B1 (en) 1998-02-13 2003-01-14 Abbott Laboratories Glucocortiocoid-selective antinflammatory agents
US6380207B2 (en) 1998-02-13 2002-04-30 Abbott Laboratories Glucocortiocoid-selective antiinflammatory agents
US6395747B1 (en) * 1998-08-10 2002-05-28 Sauro Sakoda Remedies for multiple sclerosis
WO2000034468A2 (fr) * 1998-12-11 2000-06-15 Biomira Inc. Antagonistes de la muc-1 et methodes de traitement de troubles immunitaires
JP2000212021A (ja) * 1999-01-14 2000-08-02 Pola Chem Ind Inc 皮膚外用剤
MXPA01011018A (es) 1999-04-30 2002-05-06 Pfizer Prod Inc Moduladores del receptor glucocorticoide.
MXPA01011606A (es) * 1999-05-14 2003-09-10 Univ California Terapia anti-inflamatoria para infeccion mediada por inflamacion.
US6593480B2 (en) 1999-09-01 2003-07-15 Abbott Laboratories Glucocorticoid receptor antagonists for treatment of diabetes
IL146057A (en) 2000-10-27 2007-09-20 Pfizer Prod Inc A process for the preparation of modulators of a non-steroidal glucocorticoid receptor
ES2262612T3 (es) 2000-10-28 2006-12-01 Pfizer Products Inc. Moduladpres del receptor de glucocorticoides.
JP2003055220A (ja) * 2001-08-09 2003-02-26 Taisho Pharmaceut Co Ltd イブジラスト含有眼科用組成物
JP2003055222A (ja) * 2001-08-16 2003-02-26 Rohto Pharmaceut Co Ltd 安定化された組成物
CA2473886C (fr) 2002-01-22 2012-08-21 The Regents Of The University Of California Ligands non steroidiens pour le recepteur des corticoides, compositions et utilisations desdits ligands
US20050192261A1 (en) * 2003-09-15 2005-09-01 Jost-Price Edward R. Methods and reagents for the treatment of immunoinflammatory disorders
TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
DE602004031356D1 (de) * 2003-11-21 2011-03-24 Zalicus Inc Verfahren und reagenzien zur behandlung von entzündlichen erkrankungen

Also Published As

Publication number Publication date
KR20060120208A (ko) 2006-11-24
US7709495B2 (en) 2010-05-04
DE602004031356D1 (de) 2011-03-24
BRPI0416812A (pt) 2007-03-06
WO2005051293A3 (fr) 2006-03-02
RU2006121978A (ru) 2007-12-27
US20100210606A1 (en) 2010-08-19
EP1689390A4 (fr) 2008-03-12
US20050187203A1 (en) 2005-08-25
CA2546347A1 (fr) 2005-06-09
WO2005051293A2 (fr) 2005-06-09
NZ547389A (en) 2009-11-27
CN1905870A (zh) 2007-01-31
EP1689390A2 (fr) 2006-08-16
EP1689390B1 (fr) 2011-02-09
AU2004292445B2 (en) 2010-02-04
ATE497763T1 (de) 2011-02-15
ZA200604253B (en) 2007-10-31
IL175781A0 (en) 2008-04-13
SG148198A1 (en) 2008-12-31
AU2004292445A1 (en) 2005-06-09
JP2007512337A (ja) 2007-05-17

Similar Documents

Publication Publication Date Title
NO20062300L (no) Fremgangsmater og reagenser for behandling av inflammatoriske forstyrelser
CY1116754T1 (el) Παραγωγα νιτροκατεχολης ως αναστολεις της comt
TW200517114A (en) Methods and reagents for the treatment of immunoinflammatory disorders
CY1120384T1 (el) Απταμερη θεραπευτικα χρησιμα στην αντιμετωπιση των σχετικων με το συμπληρωμα διαταραχων
SG146653A1 (en) Methods and reagents for the treatment of immunoinflammatory disorders
NO20050807L (no) Farmasoytiske sammensetninger som innbefatter dekstrometorfan og kinidin for behandling av neurologiske forstyrrelser
UA118645C2 (uk) Спосіб комбінованої терапії раку наночастинками, що містять рапаміцин і альбумін
EA200700333A1 (ru) Терапевтические применения ингибиторов rtp801
EA201270184A1 (ru) Лечение расстройств печени ингибиторами pi3k
NO20083240L (no) Sammensetninger og fremgangsmater for forebygging og behandling av kakeksia
CY1115745T1 (el) Συνθεσεις και μεθοδοι για αντιμετωπιση ή προληψη σχετιζομενης με οξαλικα νοσου
CY1112238T1 (el) Αναστολεις μιτωτικης κινεσινης και μεθοδοι χρησης αυτων
DK1651161T3 (da) Farmaceutiske præparater og fremgangsmåder til at fremme sårheling
DE602004032522D1 (de) Mit n-alkylhydroxamsäuren substituierte isoindolylverbindungen und deren pharmazeutische verwendung
NO20061245L (no) Farmasoytiske sammensetninger og fremgangsmater omfattende kombinasjoner av 2-alkyliden-19-nor-vitamin D derivater og en bisfosfon
BRPI0512500A (pt) tratamento ou condições envolvendo desmielinação
BRPI0508254A (pt) métodos e composições para o tratamento ou prevenção de distúrbios psiquiátricos com inibidores de cox-2 sozinhos e em combinação com agentes antidepressivos
ATE466595T1 (de) Verbindungen und methoden für das downregulating der effekte von tgf-beta
TW200507840A (en) Method of treating multiple myeloma
SG148186A1 (en) Methods and reagents for the treatment of inflammatory disorders
DE602004011494D1 (de) Synergistische kombination enthaltend roflumilast und einen anticholinergischen wirkstoff ausgewählt aus tiotropiumsalzen für die behandlung von atemwegserkrankungen
WO2008021048A3 (fr) Procédés et compositions fondés sur l'adp-ribosyltransférase
TW200740441A (en) Methods and reagents for the treatment of inflammatory disorders
CY1110368T1 (el) Συνεργιστικος συνδυασμος ο οποιος περιλαμβανει ροφλουμιλαστη και (r,r)-φορμοτερολη
DK1567139T3 (da) Hidtil ukendt synergistisk kombination der omfatter roflumilast og formoterol

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application