NO20071311L - Fremgangsmate ved fremstilling av citalopram - Google Patents

Fremgangsmate ved fremstilling av citalopram

Info

Publication number: NO20071311L
Authority: NO; Norway
Prior art keywords: citalopram; preparation; arylsulfonyl; alkylsulfonyl; dimethylamino
Prior art date: 1999-10-25

Application number

NO20071311A

Other languages

English (en)

Norwegian (no)

Inventor

Hans Petersen

Michael Harold Rock

Peter Ellegaard

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-25

Filing date

2007-03-09

Publication date

2001-08-24

1999-10-25 Priority claimed from PCT/DK1999/000581 external-priority patent/WO2000012044A2/en

2001-08-24 Publication of NO20071311L publication Critical patent/NO20071311L/no

2007-03-09 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

Links

WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 title abstract 3
229960001653 citalopram Drugs 0.000 title abstract 3
125000004769 (C1-C4) alkylsulfonyl group Chemical group 0.000 abstract 1
-1 3- (N, N-dimethylamino) -propylmagnesium halide Chemical class 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)

NO20071311A 1999-10-25 2007-03-09 Fremgangsmate ved fremstilling av citalopram NO20071311L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/DK1999/000581 WO2000012044A2 (en)	1999-10-25	1999-10-25	Method for the preparation of citalopram

Publications (1)

Publication Number	Publication Date
NO20071311L true NO20071311L (no)	2001-08-24

Family

ID=8157164

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20071311A NO20071311L (no)	1999-10-25	2007-03-09	Fremgangsmate ved fremstilling av citalopram

Country Status (25)

Country	Link
US (1)	US6566540B2 (de)
EP (1)	EP1298124B1 (de)
KR (1)	KR100505820B1 (de)
AR (1)	AR024518A1 (de)
AT (2)	ATE355268T1 (de)
CA (1)	CA2291133C (de)
CY (1)	CY1107635T1 (de)
CZ (1)	CZ292894B6 (de)
DE (3)	DE69935355T2 (de)
DK (2)	DK1298124T3 (de)
EA (1)	EA002801B1 (de)
ES (1)	ES2282365T3 (de)
HK (1)	HK1043129B (de)
HR (1)	HRP20020344B1 (de)
HU (1)	HUP0200169A3 (de)
IL (3)	IL143875A0 (de)
IS (1)	IS2260B (de)
NO (1)	NO20071311L (de)
NZ (1)	NZ512406A (de)
PL (1)	PL201056B1 (de)
PT (2)	PT1228056E (de)
SI (2)	SI1298124T1 (de)
SK (1)	SK287140B6 (de)
TR (1)	TR200401456T1 (de)
UA (1)	UA72238C2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR034612A1 (es) *	2001-06-25	2004-03-03	Lundbeck & Co As H	Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
TWI306846B (en) *	2002-08-12	2009-03-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
MEP5808A (xx) *	2002-12-23	2010-02-10	Lundbeck & Co As H	Ecitalopram bromhidrat i postupak za njegovo pripremanje
US20050137255A1 (en) *	2002-12-23	2005-06-23	H. Lundbeck A/S	Crystalline escitalopram hydrobromide and methods for preparing the same
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
US20050196453A1 (en) *	2004-03-05	2005-09-08	H. Lundbeck A/S	Crystalline composition containing escitalopram
EA200801080A1 (ru) *	2005-10-14	2009-02-27	Х. Лундбекк А/С	Стабильные фармацевтические лекарственные формы, содержащие эсциталопрам и бупропион
CA2625835A1 (en) *	2005-10-14	2007-05-10	Forest Laboratories, Inc.	Methods of treating central nervous system disorders with a low dose combination of escitalopram and bupropion
EP2185155B1 (de) *	2007-08-03	2017-10-04	Richter Gedeon Nyrt.	Pharmazeutische zusammensetzungen mit dopamin-rezeptor-liganden und behandlungsverfahren mit dopamin-rezeptor-liganden

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143703A (de)	1965-03-18
GB1526331A (en)	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en) *	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en) *	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
DE3926765A1 (de)	1989-08-12	1991-02-14	Hoechst Ag	Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
SK283309B6 (sk) *	1997-07-08	2003-05-02	H. Lundbeck A/S	Spôsob výroby citalopramu a medziprodukty
UA62985C2 (en) *	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
DK1042310T3 (da)	1997-11-11	2002-12-02	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
ES2189502T3 (es)	1998-10-20	2003-07-01	Lundbeck & Co As H	Metodo para la prevencion de citalopram.
IL143422A0 (en)	1998-12-23	2002-04-21	Lundbeck & Co As H	Method for the preparation of 5-cyanophthalide
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da)	1999-04-14	2010-01-04	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IES20010143A2 (en)	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
FR2805812A1 (fr)	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
CA2354877C (en)	2000-08-18	2006-05-02	H. Lundbeck A/S	Method for the preparation of citalopram
SK284418B6 (sk)	2000-12-28	2005-04-01	H. Lundbeck A/S	Spôsob výroby citalopramu

1999
- 1999-10-25 DK DK02028326T patent/DK1298124T3/da active
- 1999-10-25 HR HR20020344A patent/HRP20020344B1/xx not_active IP Right Cessation
- 1999-10-25 AT AT02028326T patent/ATE355268T1/de active
- 1999-10-25 DK DK99950511T patent/DK1228056T3/da active
- 1999-10-25 SI SI9930960T patent/SI1298124T1/sl unknown
- 1999-10-25 SK SK50008-2009A patent/SK287140B6/sk not_active IP Right Cessation
- 1999-10-25 PT PT99950511T patent/PT1228056E/pt unknown
- 1999-10-25 UA UA2001075224A patent/UA72238C2/uk unknown
- 1999-10-25 EP EP02028326A patent/EP1298124B1/de not_active Expired - Lifetime
- 1999-10-25 DE DE69935355T patent/DE69935355T2/de not_active Expired - Lifetime
- 1999-10-25 DE DE69920526T patent/DE69920526T2/de not_active Expired - Lifetime
- 1999-10-25 IL IL14387599A patent/IL143875A0/xx active IP Right Grant
- 1999-10-25 CA CA002291133A patent/CA2291133C/en not_active Expired - Fee Related
- 1999-10-25 HK HK02105036.3A patent/HK1043129B/zh not_active IP Right Cessation
- 1999-10-25 NZ NZ512406A patent/NZ512406A/xx not_active IP Right Cessation
- 1999-10-25 AT AT99950511T patent/ATE277032T1/de active
- 1999-10-25 PT PT02028326T patent/PT1298124E/pt unknown
- 1999-10-25 KR KR10-2001-7008100A patent/KR100505820B1/ko not_active Expired - Fee Related
- 1999-10-25 TR TR2004/01456T patent/TR200401456T1/xx unknown
- 1999-10-25 EA EA200100593A patent/EA002801B1/ru not_active IP Right Cessation
- 1999-10-25 DE DE19983836A patent/DE19983836C1/de not_active Expired - Fee Related
- 1999-10-25 ES ES02028326T patent/ES2282365T3/es not_active Expired - Lifetime
- 1999-10-25 HU HU0200169A patent/HUP0200169A3/hu unknown
- 1999-10-25 PL PL349440A patent/PL201056B1/pl not_active IP Right Cessation
- 1999-10-25 SI SI9930703T patent/SI1228056T1/xx unknown
- 1999-11-10 AR ARP990105703A patent/AR024518A1/es active IP Right Grant
2001
- 2001-06-15 IS IS5970A patent/IS2260B/is unknown
- 2001-06-20 IL IL143875A patent/IL143875A/en not_active IP Right Cessation
2002
- 2002-05-03 US US10/138,811 patent/US6566540B2/en not_active Expired - Fee Related
- 2002-08-29 CZ CZ20022925A patent/CZ292894B6/cs not_active IP Right Cessation
2006
- 2006-07-18 IL IL176943A patent/IL176943A0/en unknown
2007
- 2007-03-09 NO NO20071311A patent/NO20071311L/no unknown
- 2007-05-21 CY CY20071100690T patent/CY1107635T1/el unknown

Also Published As

Publication number	Publication date
EA200100593A1 (ru)	2001-10-22
HRP20020344B1 (hr)	2010-10-31
NZ512406A (en)	2004-01-30
CY1107635T1 (el)	2013-04-18
IL143875A0 (en)	2002-04-21
KR20010092799A (ko)	2001-10-27
SI1298124T1 (sl)	2007-08-31
DE69920526T2 (de)	2006-02-23
UA72238C2 (en)	2005-02-15
SK287140B6 (sk)	2010-01-07
AR024518A1 (es)	2002-10-16
US20020177722A1 (en)	2002-11-28
ATE277032T1 (de)	2004-10-15
DE19983836C1 (de)	2003-10-23
PT1298124E (pt)	2007-05-31
TR200401456T1 (tr)	2005-04-21
IS5970A (is)	2001-06-15
DE69935355T2 (de)	2007-11-08
EP1298124B1 (de)	2007-02-28
CA2291133C (en)	2003-06-17
CZ292894B6 (cs)	2003-12-17
IL143875A (en)	2008-03-20
EP1298124A1 (de)	2003-04-02
DE69935355D1 (de)	2007-04-12
PL201056B1 (pl)	2009-03-31
HUP0200169A3 (en)	2002-11-28
HUP0200169A2 (en)	2002-06-29
IS2260B (is)	2007-06-15
KR100505820B1 (ko)	2005-08-03
US6566540B2 (en)	2003-05-20
IL176943A0 (en)	2006-12-10
DK1298124T3 (da)	2007-07-09
CA2291133A1 (en)	2001-04-25
HK1043129B (zh)	2004-10-21
PL349440A1 (en)	2002-07-29
HK1043129A1 (en)	2002-09-06
DE69920526D1 (de)	2004-10-28
HRP20020344A2 (en)	2004-02-29
EA002801B1 (ru)	2002-10-31
ES2282365T3 (es)	2007-10-16
DK1228056T3 (da)	2005-01-24
SI1228056T1 (en)	2005-02-28
PT1228056E (pt)	2005-02-28
ATE355268T1 (de)	2006-03-15

Legal Events

Date	Code	Title	Description
2008-07-14	CREP	Change of representative	Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

Publication	Publication Date	Title
NO20071311L (no)	2001-08-24	Fremgangsmate ved fremstilling av citalopram
GB2360281A (en)	2001-09-19	Method for the preparation of citalopram
NO177304C (no)	1995-08-23	Analogifremgangsmåte for fremstilling av terapeutisk aktive benzimidazolderivater
NZ505954A (en)	2002-12-20	A process for preparing 2-pyridylmethylamine derivatives; their use as fungicides; and intermediates thereof
DE3270307D1 (en)	1986-05-07	Succinimide derivates and process for preparation thereof
ES2074594T3 (es)	1995-09-16	Derivados de 4-(4-alcoxifenil)-2-butilamina y su procedimiento de preparacion.
FI821733A0 (fi)	1982-05-17	Blodtryckssaenkande 1-substituerade spiropiperidinoxobenzoxazin/t
EA200200939A1 (ru)	2003-02-27	Способ получения циталопрама
SE9101482L (sv)	1991-11-18	Foerfarande foer framstaellning av mellanprodukter anvaendbara foer syntes av bensotiazepiner
DE2963729D1 (en)	1982-11-04	New intermediates and their use for the preparation of new oxadiazolo-pyrimidine derivatives
HUT78061A (hu)	1999-07-28	Eljárás 2-(aril-oxi)-4-klór-piridin-származékok előállítására
NO20033049L (no)	2003-08-18	Fremgangsmåte for fremstilling av (+/-) trans-4-p-fluorfenyl- 3-hydroksymetyl-1-metylpiperidin
GB1533694A (en)	1978-11-29	Cyclopenta(b)furan-2-ol derivatives and processes for their preparation
IT1150955B (it)	1986-12-17	Derivati 3h-naft(1.2-d)-imidazolici il procedimento per la loro preparazione, il loro uso come agenti antiinfiammatori e le composizioni farmaceutiche che li contengono
CA2164152A1 (en)	1996-09-28	New compounds of the secomacrolide and secoazalide class and a process for the preparation thereof
WO2003061552A3 (en)	2004-04-15	Novel process for the preparation of substantially pure 5-(3,5-dimethylphenoxy)methyl-2-oxazolidinone
SE8703494D0 (sv)	1987-09-09	Mellanprodukter anvendbara vid framstellning av 2-tiofen-ettiksyraderivat
NO853968L (no)	1986-04-10	Mellomprodukter for fremstilling av 16-fenoksy- og 16-subs tituerte fenoksyprostatriensyrederivater.
BG109794A (en)	2007-12-28	METHOD FOR OBTAINING A CITAL TRAIN
BG105617A (bg)	2002-01-31	Метод за получаване на циталопрам
KR890012005A (ko)	1989-08-23	K-41유도체
ATE255T1 (de)	1981-10-15	Substituierte phenylpropylhalogenide, ihre herstellung und verwendung.
FI922518A7 (fi)	1993-11-30	Menetelmä farmaseuttisesti käyttökelpoisten pilokarpiinijohdannaisten valmistamiseksi
JPS5334776A (en)	1978-03-31	Preparation of novel 3,4-dihydro-2h-pyran-2, 4-diones
KR970065536A (ko)	1997-10-13	신규 2-(피페라진-1-일)티아졸-4-카르복실산 유도체, 그의 제조방법 및 식물병원균 퇴치를 위한 그의 용도