NO20073702L - Ikke-steroid glukocorticoid reseptor modulatorer - Google Patents

Ikke-steroid glukocorticoid reseptor modulatorer

Info

Publication number
NO20073702L
NO20073702L NO20073702A NO20073702A NO20073702L NO 20073702 L NO20073702 L NO 20073702L NO 20073702 A NO20073702 A NO 20073702A NO 20073702 A NO20073702 A NO 20073702A NO 20073702 L NO20073702 L NO 20073702L
Authority
NO
Norway
Prior art keywords
glucocorticoid receptor
receptor modulators
steroid glucocorticoid
compounds
steroid
Prior art date
Application number
NO20073702A
Other languages
English (en)
Inventor
Pedro Harold Han Hermkens
Ralf Plate
Guido Jenny Rudolf Zaman
Christiaan Gerardus Johan Jans
Rogier Christian Buijsman
Adrianus Petrus Antonius D Man
Paolo Giovanni Martino Conti
Scott James Lusher
Willem Hendrik Abraham Dokter
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of NO20073702L publication Critical patent/NO20073702L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

(I) Foreliggende oppfinnelse angår forbindelser som har den generelle formel I med substituenter som definert i beskrivelsen, eller et farmasøytisk akseptabelt salt derav. Foreliggende oppfinnelse angår også farmasøytiske preparater omfattende nevnte forbindelser og anvendelse av disse derivater for å modulere glukokortikoid-reseptor-aktivitet.
NO20073702A 2005-02-14 2007-07-18 Ikke-steroid glukocorticoid reseptor modulatorer NO20073702L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05101086 2005-02-14
PCT/EP2006/050906 WO2006084917A1 (en) 2005-02-14 2006-02-14 Non steroidal glucocorticoid receptor modulators

Publications (1)

Publication Number Publication Date
NO20073702L true NO20073702L (no) 2007-09-28

Family

ID=34938730

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073702A NO20073702L (no) 2005-02-14 2007-07-18 Ikke-steroid glukocorticoid reseptor modulatorer

Country Status (30)

Country Link
US (1) US8133885B2 (no)
EP (1) EP1853601B1 (no)
JP (1) JP4922950B2 (no)
KR (1) KR101285454B1 (no)
CN (1) CN101119995B (no)
AR (1) AR054329A1 (no)
AT (1) ATE422497T1 (no)
AU (1) AU2006212192B2 (no)
BR (1) BRPI0607341A2 (no)
CA (1) CA2597748C (no)
CY (1) CY1109038T1 (no)
DE (1) DE602006005138D1 (no)
DK (1) DK1853601T3 (no)
ES (1) ES2321227T3 (no)
HR (1) HRP20090161T1 (no)
IL (1) IL184374A (no)
MX (1) MX2007008786A (no)
MY (1) MY147632A (no)
NO (1) NO20073702L (no)
NZ (1) NZ556469A (no)
PE (1) PE20061037A1 (no)
PL (1) PL1853601T3 (no)
PT (1) PT1853601E (no)
RS (1) RS50778B (no)
RU (1) RU2409577C2 (no)
SI (1) SI1853601T1 (no)
TW (1) TWI370129B (no)
UA (1) UA91352C2 (no)
WO (1) WO2006084917A1 (no)
ZA (1) ZA200705899B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
AU2008211613B2 (en) 2007-02-02 2013-05-23 Pfizer Products Inc. Tricyclic compounds and their use as glucocorticoid receptor modulators
TW200914029A (en) * 2007-05-07 2009-04-01 Organon Nv New progesterone receptor modulators
US8063037B2 (en) 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators
EP3607942B1 (en) 2008-11-07 2025-10-01 University of Sheffield Medicament and method of diagnosis
HRP20200130T1 (hr) * 2015-09-15 2020-05-15 Leo Pharma A/S Ne-steroidni modulatori glukokortikoidnog receptora za lokalni unos lijeka

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054572A (en) * 1973-04-26 1977-10-18 Akzona Incorporated Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines
TWI297685B (en) * 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
US7074806B2 (en) * 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof

Also Published As

Publication number Publication date
DE602006005138D1 (de) 2009-03-26
UA91352C2 (en) 2010-07-26
KR20070107750A (ko) 2007-11-07
US20090062262A1 (en) 2009-03-05
MX2007008786A (es) 2007-08-03
US8133885B2 (en) 2012-03-13
ZA200705899B (en) 2008-07-30
CY1109038T1 (el) 2014-07-02
EP1853601A1 (en) 2007-11-14
IL184374A0 (en) 2007-10-31
IL184374A (en) 2012-02-29
HRP20090161T1 (hr) 2009-05-31
SI1853601T1 (sl) 2009-06-30
CN101119995A (zh) 2008-02-06
KR101285454B1 (ko) 2013-07-15
TW200640923A (en) 2006-12-01
ES2321227T3 (es) 2009-06-03
TWI370129B (en) 2012-08-11
RS50778B (sr) 2010-08-31
CN101119995B (zh) 2012-01-25
CA2597748C (en) 2013-09-24
BRPI0607341A2 (pt) 2010-03-23
JP2008530056A (ja) 2008-08-07
NZ556469A (en) 2009-08-28
AR054329A1 (es) 2007-06-20
DK1853601T3 (da) 2009-05-18
AU2006212192A1 (en) 2006-08-17
PL1853601T3 (pl) 2009-07-31
AU2006212192B2 (en) 2011-06-16
WO2006084917A1 (en) 2006-08-17
RU2409577C2 (ru) 2011-01-20
JP4922950B2 (ja) 2012-04-25
PT1853601E (pt) 2009-04-09
PE20061037A1 (es) 2006-10-26
CA2597748A1 (en) 2006-08-17
ATE422497T1 (de) 2009-02-15
RU2007134226A (ru) 2009-03-20
MY147632A (en) 2012-12-31
EP1853601B1 (en) 2009-02-11

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