NO20076072L - Tigecyklin og metoder for fremstilling av 9-nitrominocyklin - Google Patents

Tigecyklin og metoder for fremstilling av 9-nitrominocyklin

Info

Publication number: NO20076072L
Authority: NO; Norway
Prior art keywords: methods; tigecycline; preparation; nitrominocycline; preparations
Prior art date: 2005-05-27

Application number

NO20076072A

Other languages

English (en)

Norwegian (no)

Inventor

Phaik-Eng Sum

Sylvain Daigneault

Michel Bernatchez

Anthony Scott Pilcher

Lalitha Krishnan

Jeffrey Marshall Horne

Adam Joseph Tuper

Iii Joseph James Mccauley

Adam P Michaud

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-05-27

Filing date

2007-11-26

Publication date

2008-02-19

2007-11-26 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-02-19 Publication of NO20076072L publication Critical patent/NO20076072L/no

Links

238000002360 preparation method Methods 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 3
229960004089 tigecycline Drugs 0.000 title abstract 2
FPZLLRFZJZRHSY-HJYUBDRYSA-N tigecycline Chemical compound C([C@H]1C2)C3=C(N(C)C)C=C(NC(=O)CNC(C)(C)C)C(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O FPZLLRFZJZRHSY-HJYUBDRYSA-N 0.000 title 1
239000004098 Tetracycline Substances 0.000 abstract 2
235000019364 tetracycline Nutrition 0.000 abstract 2
150000003522 tetracyclines Chemical class 0.000 abstract 2
SOVUOXKZCCAWOJ-HJYUBDRYSA-N (4s,4as,5ar,12ar)-9-[[2-(tert-butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1C2=C(N(C)C)C=C(NC(=O)CNC(C)(C)C)C(O)=C2C(O)=C2[C@@H]1C[C@H]1[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]1(O)C2=O SOVUOXKZCCAWOJ-HJYUBDRYSA-N 0.000 abstract 1
102000016736 Cyclin Human genes 0.000 abstract 1
108050006400 Cyclin Proteins 0.000 abstract 1
241000282376 Panthera tigris Species 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
229960002180 tetracycline Drugs 0.000 abstract 1
229930101283 tetracycline Natural products 0.000 abstract 1
229940040944 tetracyclines Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
- C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20076072A 2005-05-27 2007-11-26 Tigecyklin og metoder for fremstilling av 9-nitrominocyklin NO20076072L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68529105P	2005-05-27	2005-05-27
PCT/US2006/020540 WO2006130501A2 (en)	2005-05-27	2006-05-25	Tigecycline and methods of preparing 9-nitrominocycline

Publications (1)

Publication Number	Publication Date
NO20076072L true NO20076072L (no)	2008-02-19

Family

ID=36933528

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20076072A NO20076072L (no)	2005-05-27	2007-11-26	Tigecyklin og metoder for fremstilling av 9-nitrominocyklin

Country Status (20)

Country	Link
US (1)	US20070049560A1 (ja)
EP (1)	EP1885687A2 (ja)
JP (1)	JP2008545708A (ja)
KR (1)	KR20080016893A (ja)
CN (1)	CN101228111A (ja)
AR (1)	AR057033A1 (ja)
AU (1)	AU2006252687A1 (ja)
BR (1)	BRPI0610268A2 (ja)
CA (1)	CA2609264A1 (ja)
CR (1)	CR9543A (ja)
EC (1)	ECSP078042A (ja)
GT (1)	GT200600223A (ja)
IL (1)	IL187539A0 (ja)
MX (1)	MX2007014718A (ja)
NO (1)	NO20076072L (ja)
PE (1)	PE20061422A1 (ja)
RU (1)	RU2007143164A (ja)
TW (1)	TW200716514A (ja)
WO (1)	WO2006130501A2 (ja)
ZA (1)	ZA200710173B (ja)

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AR057649A1 (es) *	2005-05-27	2007-12-12	Wyeth Corp	Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas
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CA2649221A1 (en) *	2006-04-17	2007-10-25	Evgeny Tsiperman	Isolation of tetracycline derivatives
US8198470B2 (en)	2006-04-24	2012-06-12	Teva Pharmaceutical Industries Ltd.	Crystalline form II of tigecycline and processes for preparation thereof
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EP2236491A3 (en) *	2006-11-29	2010-11-03	Teva Pharmaceutical Industries, Ltd.	Crystalline form of tigecycline and processes for preparation thereof
EP2084126A1 (en) *	2006-11-30	2009-08-05	Teva Pharmaceutical Industries Ltd.	Processes for preparation of 9-haloacetamidominocyclines
US20080214869A1 (en) *	2007-03-01	2008-09-04	Sergei Fine	Processes for purification of tigecycline
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CN104418766B (zh) *	2013-08-26	2018-09-07	江苏豪森药业集团有限公司	替加环素的纯化方法
EP3068370A2 (en)	2013-11-12	2016-09-21	Galenicum Health S.L.	Stable pharmaceutical compositions
CN104211617A (zh) *	2014-08-29	2014-12-17	重庆康乐制药有限公司	一种替加环素的制备方法
CN111362829B (zh) *	2018-12-26	2021-11-30	浙江昌海制药有限公司	一种米诺环素二对氯苯磺酸盐晶型及其制备方法和应用
CN111060641B (zh) *	2019-12-27	2020-10-23	瀚晖制药有限公司	一种注射用替加环素中9-硝基米诺环素的检测方法
CN115768436A (zh) *	2020-08-04	2023-03-07	苏玛尔生物技术有限责任公司	改进的制备替加环素中间体的方法和由其制备替加环素的方法
CN114957031B (zh) *	2022-05-17	2024-05-31	河北圣雪大成制药有限责任公司	一种合成9-氨基米诺环素硫酸盐的新方法

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2006
- 2006-05-24 AR ARP060102155A patent/AR057033A1/es unknown
- 2006-05-25 GT GT200600223A patent/GT200600223A/es unknown
- 2006-05-25 CN CNA2006800264380A patent/CN101228111A/zh active Pending
- 2006-05-25 KR KR1020077030596A patent/KR20080016893A/ko not_active Withdrawn
- 2006-05-25 RU RU2007143164/04A patent/RU2007143164A/ru not_active Application Discontinuation
- 2006-05-25 MX MX2007014718A patent/MX2007014718A/es not_active Application Discontinuation
- 2006-05-25 JP JP2008513774A patent/JP2008545708A/ja not_active Withdrawn
- 2006-05-25 EP EP06771355A patent/EP1885687A2/en not_active Withdrawn
- 2006-05-25 CA CA002609264A patent/CA2609264A1/en not_active Abandoned
- 2006-05-25 BR BRPI0610268-9A patent/BRPI0610268A2/pt not_active IP Right Cessation
- 2006-05-25 AU AU2006252687A patent/AU2006252687A1/en not_active Abandoned
- 2006-05-25 PE PE2006000554A patent/PE20061422A1/es not_active Application Discontinuation
- 2006-05-25 WO PCT/US2006/020540 patent/WO2006130501A2/en not_active Ceased
- 2006-05-25 TW TW095118576A patent/TW200716514A/zh unknown
- 2006-05-25 US US11/440,031 patent/US20070049560A1/en not_active Abandoned
2007
- 2007-11-21 IL IL187539A patent/IL187539A0/en unknown
- 2007-11-22 CR CR9543A patent/CR9543A/es not_active Application Discontinuation
- 2007-11-26 ZA ZA200710173A patent/ZA200710173B/xx unknown
- 2007-11-26 NO NO20076072A patent/NO20076072L/no not_active Application Discontinuation
- 2007-12-20 EC EC2007008042A patent/ECSP078042A/es unknown

Also Published As

Publication number	Publication date
BRPI0610268A2 (pt)	2010-06-08
CN101228111A (zh)	2008-07-23
GT200600223A (es)	2007-05-08
ECSP078042A (es)	2008-01-23
WO2006130501A2 (en)	2006-12-07
CA2609264A1 (en)	2006-12-07
MX2007014718A (es)	2008-02-15
JP2008545708A (ja)	2008-12-18
PE20061422A1 (es)	2007-01-29
AR057033A1 (es)	2007-11-14
WO2006130501A3 (en)	2007-03-29
TW200716514A (en)	2007-05-01
ZA200710173B (en)	2009-09-30
EP1885687A2 (en)	2008-02-13
IL187539A0 (en)	2008-03-20
AU2006252687A1 (en)	2006-12-07
US20070049560A1 (en)	2007-03-01
RU2007143164A (ru)	2009-07-10
CR9543A (es)	2008-02-20
KR20080016893A (ko)	2008-02-22

Legal Events

Date	Code	Title	Description
2009-12-21	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20076072L (no)	2008-02-19	Tigecyklin og metoder for fremstilling av 9-nitrominocyklin
NO20075997L (no)	2008-02-19	Methoder til furifysering av tigecyklin
NO20076001L (no)	2008-02-19	Tigecyklin og metoder for deres fremstilling
NO20075998L (no)	2008-02-19	Tigecyklin og metoder til fremstilling av 9-aminominocyklin
NO20075693L (no)	2008-02-07	Modulerende forbindelser av indolamin-2,3-dioksygenase og fremgangsmater for anvendelse av samme
NO20081042L (no)	2008-05-22	PPAR aktive forbindelser
NO20083147L (no)	2008-09-16	Anti-OX40L-antistoffer og fremgangsmater for anvendelse av disse
EA201000491A1 (ru)	2010-08-30	Аминометилзамещенные тетрациклиновые соединения
HUS1800021I1 (hu)	2018-06-28	Humán anti-Il-23 ellenanyagok, készítmények, eljárások és alkalmazások
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CY1114916T1 (el)	2016-12-14	Μεθοδοι
DK1682530T3 (da)	2007-07-16	Pyrrolsubstituerede indoler som inhibitorer af PAI-1
NO20065329L (no)	2006-12-19	Fremstilling av pregabalin og beslektede forbindelser.
NO20080784L (no)	2008-03-31	Histondeacetylaseinhibitorer
WO2007014154A3 (en)	2007-08-23	10-substituted tetracyclines and methods of use thereof
NO20062709L (no)	2006-08-11	Stamceller som er egnet for transplantasjon, fremstilling derav og farmasoytiske preperater omfattende nevnte stamceller
TW200720232A (en)	2007-06-01	Crystalline solid forms of tigecycline and methods of preparing same
NO20062649L (no)	2006-09-01	Biarylsulfonamider og metoder for anvendelse av disse
WO2008045507A3 (en)	2008-05-29	Substituted tetracycline compounds for treatment of bacillus anthracis infections
EA200801560A1 (ru)	2008-12-30	Бифенилкарбоксамиды
NO20072290L (no)	2007-05-30	Organiske forbindelser.
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