NO20080536L - Oksazolidinonderivater og deres anvendelse som antibiotika - Google Patents

Oksazolidinonderivater og deres anvendelse som antibiotika

Info

Publication number
NO20080536L
NO20080536L NO20080536A NO20080536A NO20080536L NO 20080536 L NO20080536 L NO 20080536L NO 20080536 A NO20080536 A NO 20080536A NO 20080536 A NO20080536 A NO 20080536A NO 20080536 L NO20080536 L NO 20080536L
Authority
NO
Norway
Prior art keywords
compounds
antibiotics
different meanings
gram
oxazolidinone derivatives
Prior art date
Application number
NO20080536A
Other languages
English (en)
Inventor
Antonio Guglietta
Montserrat Cano
Albert Palomer
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34982564&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20080536(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of NO20080536L publication Critical patent/NO20080536L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

der A er visse heterosykler som eventuelt er substituert; Ri, R2, R3 og R4 uavhengig er valgt blant -H og halogen; X er valgt blant O, S, NR9 og CR9R10; R9 og Rio har forskjellige betydninger; Y er valgt blant O, S, SO, SO2, NO, NR]2 og CRi2Ri3; R12 og Ri3 har forskjellige betydninger. Det tilveiebringes videre forskjellige prosesser for fremstilling av slike forbindelser. Oksazolidinonforbindelsene med formel (I) er aktive mot grampositive og noen gramnegative human- og veterinærpatogener med en svak monoaminoksidase(MAO)-inhibitorisk aktivitet. Forbindelsene finner anvendelse ved behandling av bakterielle infeksjoner.
NO20080536A 2005-06-27 2008-01-28 Oksazolidinonderivater og deres anvendelse som antibiotika NO20080536L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105714A EP1745784A1 (en) 2005-06-27 2005-06-27 Oxazolidinone derivatives and use thereof as antibiotics
PCT/EP2006/063541 WO2007000432A1 (en) 2005-06-27 2006-06-26 Oxazolidinone derivatives and use thereof as antibiotics

Publications (1)

Publication Number Publication Date
NO20080536L true NO20080536L (no) 2008-03-14

Family

ID=34982564

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080536A NO20080536L (no) 2005-06-27 2008-01-28 Oksazolidinonderivater og deres anvendelse som antibiotika

Country Status (22)

Country Link
US (1) US7759351B2 (no)
EP (2) EP1745784A1 (no)
JP (1) JP2008543963A (no)
KR (1) KR20080020696A (no)
CN (1) CN101248067A (no)
AR (1) AR054625A1 (no)
AT (1) ATE442366T1 (no)
AU (1) AU2006263880A1 (no)
BR (1) BRPI0612559A2 (no)
CA (1) CA2612969A1 (no)
CY (1) CY1109544T1 (no)
DE (1) DE602006009112D1 (no)
DK (1) DK1902050T3 (no)
ES (1) ES2333469T3 (no)
MX (1) MX2007016329A (no)
NO (1) NO20080536L (no)
PL (1) PL1902050T3 (no)
PT (1) PT1902050E (no)
RU (1) RU2417223C2 (no)
SI (1) SI1902050T1 (no)
TW (1) TWI324603B (no)
WO (1) WO2007000432A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2710039C (en) 2007-12-26 2018-07-03 Critical Outcome Technologies, Inc. Semicarbazones, thiosemicarbazones and related compounds and methods for treatment of cancer
EP2318406B1 (en) 2008-07-17 2016-01-27 Critical Outcome Technologies, Inc. Thiosemicarbazone inhibitor compounds and cancer treatment methods
EP2367820B1 (en) 2008-11-20 2016-09-21 Panacea Biotec Limited Novel antimicrobial agents
BR112012000657A2 (pt) 2009-06-26 2016-11-16 Panacea Biotec Ltd novos azabicilohexanos
CA2999435A1 (en) 2010-04-01 2011-10-06 Critical Outcome Technologies Inc. Compounds and method for treatment of hiv
US20160152579A1 (en) * 2013-07-11 2016-06-02 Servicio Andaluz De Salud Oxazolidinone derivatives as ppar ligands
CN103420995B (zh) * 2013-09-07 2015-07-01 吉首大学 噁唑烷酮-烷胺基-呋喃酮型化合物及其制法和用途
CN104447730B (zh) * 2014-12-05 2017-11-07 广东东阳光药业有限公司 噁唑烷酮类化合物及其在药物中的应用
TWI614256B (zh) 2017-05-26 2018-02-11 合成四氫異喹啉噁唑烷的方法
CN111164071A (zh) * 2017-09-28 2020-05-15 株式会社Lg化学 用于合成药物的中间体化合物的制备方法
WO2021184339A1 (en) 2020-03-20 2021-09-23 Merck Sharp & Dohme Corp. Oxazolidinone compound and methods of use thereof as an antibacterial agent
WO2021258013A1 (en) 2020-06-18 2021-12-23 Akagera Medicines, Inc. Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof
CN115466253B (zh) * 2021-06-16 2024-08-20 沈阳药科大学 含二硫代氨基甲酸酯结构的噁唑烷酮类化合物及其制备方法
CN113880821B (zh) * 2021-10-29 2024-03-12 南京碳硅人工智能生物医药技术研究院有限公司 一类双光子荧光探针对癫痫脑内次氯酸特征成像的荧光探针设计及其合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2175324C2 (ru) * 1995-09-01 2001-10-27 Фармация Энд Апджон Компани Фенилоксазолидиноны, имеющие с-с-связь с 4-8-членными гетероциклическими кольцами
CA2463794A1 (en) * 2001-11-29 2003-06-12 Merck & Co., Inc. Cyclopropyl hexane containing oxazolidinone antibiotics and derivatives thereof
BR0308806A (pt) * 2002-03-29 2005-01-04 Upjohn Co Uso de oxazolidinonas para tratar infecções do tipo pé diabético
EP1565461A2 (en) * 2002-07-11 2005-08-24 Mahesh V. Patel Antibacterial substituted cyanomethyl(ene)piperidinophenyl oxazolidinones, process for their preparation, and pharmaceutical compositions containing them
US20080214565A1 (en) * 2003-04-07 2008-09-04 Anita Mehta Oxazolidinone Derivatives as Antimicrobials

Also Published As

Publication number Publication date
EP1902050A1 (en) 2008-03-26
AR054625A1 (es) 2007-07-04
CY1109544T1 (el) 2014-08-13
RU2008102597A (ru) 2009-08-10
DK1902050T3 (da) 2010-01-04
TWI324603B (en) 2010-05-11
EP1902050B1 (en) 2009-09-09
MX2007016329A (es) 2008-03-10
CN101248067A (zh) 2008-08-20
CA2612969A1 (en) 2007-01-04
TW200740800A (en) 2007-11-01
HK1116482A1 (en) 2008-12-24
PT1902050E (pt) 2009-11-27
WO2007000432A1 (en) 2007-01-04
EP1745784A1 (en) 2007-01-24
ES2333469T3 (es) 2010-02-22
BRPI0612559A2 (pt) 2010-11-23
US7759351B2 (en) 2010-07-20
PL1902050T3 (pl) 2010-03-31
DE602006009112D1 (de) 2009-10-22
JP2008543963A (ja) 2008-12-04
SI1902050T1 (sl) 2010-01-29
AU2006263880A1 (en) 2007-01-04
KR20080020696A (ko) 2008-03-05
US20090062266A1 (en) 2009-03-05
ATE442366T1 (de) 2009-09-15
RU2417223C2 (ru) 2011-04-27

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