NO20080831L - 1,4-dihydropyridin-fuserte heterosykler, fremgangsmate for fremstilling av det samme, anvendelse og sammensetninger inneholdende dem - Google Patents

1,4-dihydropyridin-fuserte heterosykler, fremgangsmate for fremstilling av det samme, anvendelse og sammensetninger inneholdende dem

Info

Publication number
NO20080831L
NO20080831L NO20080831A NO20080831A NO20080831L NO 20080831 L NO20080831 L NO 20080831L NO 20080831 A NO20080831 A NO 20080831A NO 20080831 A NO20080831 A NO 20080831A NO 20080831 L NO20080831 L NO 20080831L
Authority
NO
Norway
Prior art keywords
dihydropyridine
preparing
same
compositions containing
fused heterocycles
Prior art date
Application number
NO20080831A
Other languages
English (en)
Norwegian (no)
Inventor
Jacques Mauger
Serge Mignani
Odile Angouillant-Boniface
Anil Nair
Bruno Filoche-Romme
Kirsten Bjergarde
Nina Ma
Jean-Christophe Carry
Francois Clerc
Herve Minoux
Laurent Schio
Cecile Combeau
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of NO20080831L publication Critical patent/NO20080831L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO20080831A 2005-07-20 2008-02-15 1,4-dihydropyridin-fuserte heterosykler, fremgangsmate for fremstilling av det samme, anvendelse og sammensetninger inneholdende dem NO20080831L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05291558A EP1746097B1 (fr) 2005-07-20 2005-07-20 Héterocyles à fusion1,4-dihydropyridineprocédé de préparation, utilisation et compositions de celles-ci
PCT/IB2006/002734 WO2007012972A2 (fr) 2005-07-20 2006-07-18 Heterocycles fusionnes de 1,4-dihydropyridine, procede pour preparer ceux-ci, utilisations et compositions les contenant

Publications (1)

Publication Number Publication Date
NO20080831L true NO20080831L (no) 2008-04-03

Family

ID=35510894

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080831A NO20080831L (no) 2005-07-20 2008-02-15 1,4-dihydropyridin-fuserte heterosykler, fremgangsmate for fremstilling av det samme, anvendelse og sammensetninger inneholdende dem

Country Status (37)

Country Link
US (1) US8163768B2 (fr)
EP (2) EP1746097B1 (fr)
JP (2) JP2009501778A (fr)
KR (1) KR101286796B1 (fr)
CN (1) CN101243087B (fr)
AR (1) AR054845A1 (fr)
AT (2) ATE455115T1 (fr)
AU (1) AU2006273692B8 (fr)
BR (1) BRPI0614002A2 (fr)
CA (1) CA2615700C (fr)
CR (1) CR9663A (fr)
CY (1) CY1109964T1 (fr)
DE (1) DE602005018911D1 (fr)
DK (1) DK1746097T3 (fr)
DO (1) DOP2006000175A (fr)
EA (1) EA016815B1 (fr)
EC (1) ECSP078062A (fr)
ES (1) ES2339676T3 (fr)
HN (1) HN2008000088A (fr)
HR (1) HRP20100195T1 (fr)
IL (1) IL188861A0 (fr)
MA (1) MA29634B1 (fr)
MX (1) MX2008000902A (fr)
MY (1) MY148617A (fr)
NO (1) NO20080831L (fr)
NZ (1) NZ592766A (fr)
PE (2) PE20100718A1 (fr)
PL (1) PL1746097T3 (fr)
PT (1) PT1746097E (fr)
RS (1) RS51351B (fr)
SI (1) SI1746097T1 (fr)
TN (1) TNSN08020A1 (fr)
TW (1) TWI386411B (fr)
UA (1) UA98928C2 (fr)
UY (1) UY29685A1 (fr)
WO (1) WO2007012972A2 (fr)
ZA (1) ZA200800542B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2945535B1 (fr) * 2009-05-18 2011-06-10 Sanofi Aventis Compose anticancereux et composition pharmaceutique le contenant
FR2967413A1 (fr) * 2010-11-17 2012-05-18 Sanofi Aventis Compose 8-oxo-9-[3-(1h-benzimidazol-2-yloxy)-phenyl]-4,5,6,7,8,9-hexahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate d'ethyle, sel, forme cristalline, co-cristal, formulation, procedes de preparation, application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteur des kinases aurora.
WO2013171640A1 (fr) 2012-05-15 2013-11-21 Novartis Ag Dérivés de benzamide pour inhiber l'activité d'abl1, d'abl2 et de bcr-abl2
ES2670601T3 (es) 2012-05-15 2018-05-31 Novartis Ag Derivados de benzamida para la inhibición de la actividad de ABL1, ABL2 y BCR-ABL1
KR20150008406A (ko) 2012-05-15 2015-01-22 노파르티스 아게 Abl1, abl2 및 bcr-abl1의 활성을 억제하기 위한 벤즈아미드 유도체
MX357305B (es) 2012-05-15 2018-07-04 Novartis Ag Compuestos y composiciones para inhibir la actividad de abl-1, abl-2, y bcr-abl1.
DK2909204T3 (en) * 2012-10-12 2019-04-01 Broad Inst Inc GSK3 INHIBITORS AND METHODS FOR USE THEREOF
CA2968884A1 (fr) 2014-12-10 2016-06-16 Massachusetts Institute Of Technology Derives fusionnes de 1,3-azole utiles pour le traitement de maladies proliferatives
EP4212532A3 (fr) 2015-04-30 2023-09-27 Memorial Sloan Kettering Cancer Center Analogues de la mitragynine et leurs utilisations
RU2619932C1 (ru) * 2015-11-25 2017-05-22 федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") ЗАМЕЩЕННЫЕ ПИРАЗОЛО[1,5-а]ПИРИДО[3,4-е]ПИРИМИДИНЫ И ИХ ИСПОЛЬЗОВАНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ ПРОТЕИНКИНАЗ
WO2017124087A1 (fr) 2016-01-15 2017-07-20 Memorial Sloan-Kettering Cancer Center Composés antiparasitaires et leurs utilisations
RU2018132559A (ru) 2016-02-16 2020-03-17 Массачусетс Инститьют Оф Текнолоджи Связывающие молекулы для max в качестве модуляторов myc и их применения
KR20190136063A (ko) 2017-04-05 2019-12-09 더 브로드 인스티튜트, 인코퍼레이티드 글리코겐 신타제 키나제 3 (gsk3) 억제제로서의 트리시클릭 화합물 및 그의 용도
JP7455581B2 (ja) 2017-05-12 2024-03-26 リサーチ トライアングル インスティテュート Ｃｂ１アロステリック・モジュレーターとしてのジアリール尿素

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1043998B1 (fr) * 1997-12-13 2007-03-07 Bristol-Myers Squibb Company UTILISATION DE PYRAZOLO [3,4-b]PYRIDINE EN TANT QU'INHIBITEURS DE KINASE DEPENDANT DE LA CYCLINE
CA2391291A1 (fr) 1999-11-19 2001-05-25 Abbott Laboratories Ouvreurs de canaux potassiques du type dihydropyrimidine tricyclique
CA2402179A1 (fr) 2000-03-03 2001-09-13 Abbott Laboratories Agents ouvrant les canaux potassium a base de dihydropyrazolone tricyclique et de dihydroisoxazolone tricyclique
US6538004B2 (en) 2000-03-03 2003-03-25 Abbott Laboratories Tricyclic dihydropyrazolone and tricyclic dihydroisoxazolone potassium channel openers
KR20030076650A (ko) 2001-02-02 2003-09-26 미쯔비시 웰 파마 가부시키가이샤 디하이드로피라졸로피리딘 화합물 및 그의 약학적 용도
FR2823854A1 (fr) * 2001-04-18 2002-10-25 Centre Nat Rech Scient Nouveau procede de criblage d'inhibiteurs de la liaison entre la proteine oxyde nitrique synthase neuronale et la proteine inhibitrice de l'oxyde nitrique synthase neuronale
FR2825091B1 (fr) * 2001-05-23 2003-07-04 Servier Lab Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7037902B2 (en) * 2002-07-03 2006-05-02 Receptron, Inc. Affinity small molecules for the EPO receptor
SE0301371D0 (sv) 2003-05-09 2003-05-09 Astrazeneca Ab New Compounds
CA2528938A1 (fr) * 2003-06-13 2005-02-24 Zentaris Gmbh Composes presentant une activite inhibitrice de la phosphatidylinositol 3-kinase

Also Published As

Publication number Publication date
MY148617A (en) 2013-05-15
NZ592766A (en) 2012-12-21
ATE455115T1 (de) 2010-01-15
AU2006273692A8 (en) 2012-12-13
CA2615700C (fr) 2013-06-18
CY1109964T1 (el) 2014-09-10
UA98928C2 (ru) 2012-07-10
TWI386411B (zh) 2013-02-21
CR9663A (es) 2008-02-21
TNSN08020A1 (en) 2009-07-14
ZA200800542B (en) 2010-02-24
ATE521611T1 (de) 2011-09-15
AR054845A1 (es) 2007-07-18
RS51351B (sr) 2011-02-28
JP2009501778A (ja) 2009-01-22
JP2013063987A (ja) 2013-04-11
HN2008000088A (es) 2011-05-31
DOP2006000175A (es) 2007-03-31
US20080261969A1 (en) 2008-10-23
AU2006273692A1 (en) 2007-02-01
CA2615700A1 (fr) 2007-02-01
AU2006273692B8 (en) 2012-12-13
CN101243087A (zh) 2008-08-13
UY29685A1 (es) 2007-02-28
TW200740812A (en) 2007-11-01
PT1746097E (pt) 2010-04-15
MA29634B1 (fr) 2008-07-01
EP1746097B1 (fr) 2010-01-13
EA200800374A1 (ru) 2008-08-29
ES2339676T3 (es) 2010-05-24
WO2007012972A2 (fr) 2007-02-01
ECSP078062A (es) 2008-01-23
SI1746097T1 (sl) 2010-05-31
MX2008000902A (es) 2008-03-26
PE20100718A1 (es) 2010-10-20
US8163768B2 (en) 2012-04-24
EP1746097A1 (fr) 2007-01-24
HRP20100195T1 (hr) 2010-05-31
DE602005018911D1 (de) 2010-03-04
EP1910366A2 (fr) 2008-04-16
KR20080026658A (ko) 2008-03-25
EP1910366B1 (fr) 2011-08-24
BRPI0614002A2 (pt) 2011-03-01
WO2007012972A3 (fr) 2007-04-05
CN101243087B (zh) 2013-07-24
AU2006273692B2 (en) 2012-11-22
PE20070212A1 (es) 2007-03-21
KR101286796B1 (ko) 2013-07-17
PL1746097T3 (pl) 2010-06-30
DK1746097T3 (da) 2010-05-25
EA016815B1 (ru) 2012-07-30
IL188861A0 (en) 2008-04-13

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