NO20082530L - Imidazopyraziner som proteinkinaseinhibitorer - Google Patents

Imidazopyraziner som proteinkinaseinhibitorer

Info

Publication number: NO20082530L
Authority: NO; Norway
Prior art keywords: compounds; imidazopyrazines; protein kinase; kinase inhibitors; protein
Prior art date: 2005-11-10

Application number

NO20082530A

Other languages

English (en)

Norwegian (no)

Inventor

Timothy J Guzi

Michael Dwyer

Kamil Paruch

Lianyun Zhao

Patrick J Curran

David B Belanger

Blake Hamann

Panduranga A Reddy

M Arshad Siddiqui

Praveen K Tadikonda

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-10

Filing date

2008-06-06

Publication date

2008-08-07

2008-06-06 Application filed by Schering Corp filed Critical Schering Corp

2008-08-07 Publication of NO20082530L publication Critical patent/NO20082530L/no

Links

150000005235 imidazopyrazines Chemical class 0.000 title abstract 2
229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
239000003909 protein kinase inhibitor Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 4
238000000034 method Methods 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
108091000080 Phosphotransferase Proteins 0.000 abstract 1
102000001253 Protein Kinase Human genes 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
102000020233 phosphotransferase Human genes 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
108060006633 protein kinase Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Virology (AREA)
Neurology (AREA)
Oncology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Communicable Diseases (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Biotechnology (AREA)
Endocrinology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Tropical Medicine & Parasitology (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)

NO20082530A 2005-11-10 2008-06-06 Imidazopyraziner som proteinkinaseinhibitorer NO20082530L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73598205P	2005-11-10	2005-11-10
PCT/US2006/043786 WO2007058942A2 (en)	2005-11-10	2006-11-08	Imidazopyrazines as protein kinase inhibitors

Publications (1)

Publication Number	Publication Date
NO20082530L true NO20082530L (no)	2008-08-07

Family

ID=38008330

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20082530A NO20082530L (no)	2005-11-10	2008-06-06	Imidazopyraziner som proteinkinaseinhibitorer

Country Status (17)

Country	Link
US (1)	US20070117804A1 (de)
EP (1)	EP1945644A2 (de)
JP (1)	JP5031760B2 (de)
KR (1)	KR20080074963A (de)
CN (1)	CN101370811A (de)
AR (1)	AR056785A1 (de)
AU (1)	AU2006315718B2 (de)
BR (1)	BRPI0618520A2 (de)
CA (1)	CA2628455A1 (de)
EC (1)	ECSP088440A (de)
IL (1)	IL191294A0 (de)
NO (1)	NO20082530L (de)
PE (1)	PE20070805A1 (de)
RU (1)	RU2008122967A (de)
TW (1)	TW200804386A (de)
WO (1)	WO2007058942A2 (de)
ZA (1)	ZA200803894B (de)

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US20100249030A1 (en) *	2007-07-31	2010-09-30	Schering Corporation	Anti-mitotic agent and aurora kinase inhibitor combination as anti-cancer treatment
GB0716292D0 (en)	2007-08-21	2007-09-26	Biofocus Dpi Ltd	Imidazopyrazine compounds
EP2216052A4 (de) *	2007-10-30	2012-11-21	Nihon Mediphysics Co Ltd	Verwendung einer neuen verbindung mit affinität für amyloid und verfahren zu ihrer herstellung
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JP5377329B2 (ja) *	2007-12-26	2013-12-25	Ｍｓｄ株式会社	スルホニル置換六員環誘導体
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US20090207142A1 (en) *	2008-02-20	2009-08-20	Nokia Corporation	Apparatus, method, computer program and user interface for enabling user input
US8168794B2 (en)	2008-03-03	2012-05-01	Novartis Ag	Pim kinase inhibitors and methods of their use
PE20091577A1 (es) *	2008-03-03	2009-11-05	Novartis Ag	Inhibidores de cinasa pim y metodos para su uso
FR2933409B1 (fr) *	2008-07-03	2010-08-27	Centre Nat Rech Scient	NOUVEAUX PYRROLO °2,3-a! CARBAZOLES ET LEUR UTILISATION COMME INHIBITEURS DES KINASES PIM
US8450321B2 (en)	2008-12-08	2013-05-28	Gilead Connecticut, Inc.	6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
PL2716157T3 (pl)	2008-12-08	2017-06-30	Gilead Connecticut, Inc.	Imidazopirazynowe inhibitory Syk
PE20120121A1 (es)	2008-12-08	2012-02-20	Gilead Connecticut Inc	Derivados de imidazopirazina como inhibidores de syk
TW201107329A (en)	2009-07-30	2011-03-01	Oncotherapy Science Inc	Fused imidazole derivative having ttk inhibitory action
EP2473041B1 (de)	2009-09-04	2018-03-07	Merck Sharp & Dohme Corp.	Modulatoren von zellzyklus-kontrollpunkten und ihre verwendung in kombination mit kontrollpunkt-kinasehemmern
KR101774035B1 (ko)	2009-10-30	2017-09-01	얀센 파마슈티카 엔.브이.	이미다조［１，２―ｂ］피리다진 유도체 및 ＰＤＥ１０ 저해제로서의 그의 용도
EP2523949B1 (de)	2010-01-15	2014-08-20	Janssen Pharmaceuticals Inc.	Neuartige substituierte Triazolderivate als Gamma-Sekretase-Modulatoren
US8470820B2 (en)	2010-01-22	2013-06-25	Hoffman-La Roche Inc.	Nitrogen-containing heteroaryl derivatives
JP5764145B2 (ja) *	2010-02-08	2015-08-12	メルク・シャープ・エンド・ドーム・ベー・フェー	８−メチル−１−フェニル−イミダゾル［１，５−ａ］ピラジン化合物
AR080754A1 (es)	2010-03-09	2012-05-09	Janssen Pharmaceutica Nv	Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
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JP5824040B2 (ja) *	2010-06-01	2015-11-25	バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＧｍｂＨ	置換イミダゾピラジン
TWI541243B (zh) *	2010-09-10	2016-07-11	拜耳知識產權公司	經取代咪唑并嗒
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AU2006315718B2 (en)	2012-10-04
IL191294A0 (en)	2009-02-11
EP1945644A2 (de)	2008-07-23
TW200804386A (en)	2008-01-16
CA2628455A1 (en)	2007-05-24
JP2009515888A (ja)	2009-04-16
AR056785A1 (es)	2007-10-24
ECSP088440A (es)	2008-06-30
PE20070805A1 (es)	2007-08-13
ZA200803894B (en)	2009-03-25
CN101370811A (zh)	2009-02-18
JP5031760B2 (ja)	2012-09-26
RU2008122967A (ru)	2009-12-20
WO2007058942A3 (en)	2007-11-15
US20070117804A1 (en)	2007-05-24
KR20080074963A (ko)	2008-08-13
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