NO20091379L - Effektiv syntese av chelatorer for nukleaer bildebehandling og radioterapi: blandinger og anvendelser - Google Patents

Effektiv syntese av chelatorer for nukleaer bildebehandling og radioterapi: blandinger og anvendelser

Info

Publication number
NO20091379L
NO20091379L NO20091379A NO20091379A NO20091379L NO 20091379 L NO20091379 L NO 20091379L NO 20091379 A NO20091379 A NO 20091379A NO 20091379 A NO20091379 A NO 20091379A NO 20091379 L NO20091379 L NO 20091379L
Authority
NO
Norway
Prior art keywords
compositions
methods
applications
chelators
radiotherapy
Prior art date
Application number
NO20091379A
Other languages
English (en)
Other versions
NO343348B1 (no
Inventor
David J Yang
Dongfang Yu
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of NO20091379L publication Critical patent/NO20091379L/no
Publication of NO343348B1 publication Critical patent/NO343348B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Nye metoder for syntese av chelator-målsøkende ligandkonjugater, preparater omfattende slike konjugater og terapeutiske og diagnostiske applikasjoner av slike konjugater er beskrevet. Preparatene omfatter chelator?målsøkende ligandkonjugater eventuelt chelatert til én eller flere metallioner. Metoder for syntetisering av disse preparater med høy renhet er også presentert. Også beskrevet er metoder for avbildning, behandling av og diagnostisering av sykdom i et individ ved anvendelse av disse nye preparater, så som metoder for avbildning en tumor i et individ og metoder for diagnostisering av myokardial ischemi.
NO20091379A 2006-10-05 2009-04-03 Syntese av chelatorer og slike forbindelser for nukleær bildebehandling og diagnose NO343348B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82834706P 2006-10-05 2006-10-05
US11/770,395 US10925977B2 (en) 2006-10-05 2007-06-28 Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
PCT/US2007/072669 WO2008045604A2 (en) 2006-10-05 2007-07-02 Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

Publications (2)

Publication Number Publication Date
NO20091379L true NO20091379L (no) 2009-04-21
NO343348B1 NO343348B1 (no) 2019-02-04

Family

ID=38667097

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091379A NO343348B1 (no) 2006-10-05 2009-04-03 Syntese av chelatorer og slike forbindelser for nukleær bildebehandling og diagnose

Country Status (20)

Country Link
US (2) US10925977B2 (no)
EP (1) EP2079486B1 (no)
JP (1) JP5541922B2 (no)
KR (2) KR101513003B1 (no)
CN (2) CN104800862A (no)
AU (1) AU2007308022B2 (no)
BR (1) BRPI0719532B1 (no)
CA (2) CA2664826C (no)
DK (1) DK2079486T3 (no)
ES (1) ES2674910T3 (no)
HK (1) HK1212634A1 (no)
HU (1) HUE038650T2 (no)
IL (2) IL197972A (no)
NO (1) NO343348B1 (no)
PL (1) PL2079486T3 (no)
PT (1) PT2079486T (no)
RU (1) RU2512491C2 (no)
SI (1) SI2079486T1 (no)
TR (1) TR201808820T4 (no)
WO (1) WO2008045604A2 (no)

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BRPI0719532B1 (pt) 2022-03-29
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EP2079486B1 (en) 2018-04-04
US20080107598A1 (en) 2008-05-08
AU2007308022B2 (en) 2013-05-09
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CN104800862A (zh) 2015-07-29
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IL197972A (en) 2014-03-31
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