NO303513B1 - FremgangsmÕte for pÕvisning, kvantifisering og/eller isolering av apoptotiske celler i en pr°ve, anvendelse av fremgangsmÕten og sett for utf°relse - Google Patents

FremgangsmÕte for pÕvisning, kvantifisering og/eller isolering av apoptotiske celler i en pr°ve, anvendelse av fremgangsmÕten og sett for utf°relse

Info

Publication number
NO303513B1
NO303513B1 NO964308A NO964308A NO303513B1 NO 303513 B1 NO303513 B1 NO 303513B1 NO 964308 A NO964308 A NO 964308A NO 964308 A NO964308 A NO 964308A NO 303513 B1 NO303513 B1 NO 303513B1
Authority
NO
Norway
Prior art keywords
apoptotic cells
pct
high affinity
phosphatidyl serine
sample
Prior art date
Application number
NO964308A
Other languages
English (en)
Norwegian (no)
Other versions
NO964308D0 (no
NO964308L (no
Inventor
Christiaan Pe Reutelingsperger
Original Assignee
Nexins Research Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8216787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO303513(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nexins Research Bv filed Critical Nexins Research Bv
Publication of NO964308D0 publication Critical patent/NO964308D0/no
Publication of NO964308L publication Critical patent/NO964308L/no
Publication of NO303513B1 publication Critical patent/NO303513B1/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2510/00—Detection of programmed cell death, i.e. apoptosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
NO964308A 1994-04-11 1996-10-10 FremgangsmÕte for pÕvisning, kvantifisering og/eller isolering av apoptotiske celler i en pr°ve, anvendelse av fremgangsmÕten og sett for utf°relse NO303513B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94200968 1994-04-11
PCT/NL1995/000134 WO1995027903A1 (fr) 1994-04-11 1995-04-11 Procede de detection et/ou de quantification eventuelle et/ou de separation de cellules apoptotiques dans ou depuis un echantillon

Publications (3)

Publication Number Publication Date
NO964308D0 NO964308D0 (no) 1996-10-10
NO964308L NO964308L (no) 1996-12-11
NO303513B1 true NO303513B1 (no) 1998-07-20

Family

ID=8216787

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964308A NO303513B1 (no) 1994-04-11 1996-10-10 FremgangsmÕte for pÕvisning, kvantifisering og/eller isolering av apoptotiske celler i en pr°ve, anvendelse av fremgangsmÕten og sett for utf°relse

Country Status (12)

Country Link
US (1) US5834196A (fr)
EP (1) EP0755516B1 (fr)
JP (1) JP2824155B2 (fr)
AT (1) ATE160875T1 (fr)
AU (1) AU689248B2 (fr)
CA (1) CA2185535C (fr)
DE (1) DE69501161T2 (fr)
DK (1) DK0755516T3 (fr)
ES (1) ES2112057T3 (fr)
NO (1) NO303513B1 (fr)
NZ (1) NZ283171A (fr)
WO (1) WO1995027903A1 (fr)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804436A (en) 1996-08-02 1998-09-08 Axiom Biotechnologies, Inc. Apparatus and method for real-time measurement of cellular response
US6280967B1 (en) * 1996-08-02 2001-08-28 Axiom Biotechnologies, Inc. Cell flow apparatus and method for real-time of cellular responses
US6558916B2 (en) 1996-08-02 2003-05-06 Axiom Biotechnologies, Inc. Cell flow apparatus and method for real-time measurements of patient cellular responses
HUP0001261A3 (en) 1997-04-30 2001-11-28 Univ Washington Seattle Method of imaging cell death in vivo
US6270980B1 (en) 1997-06-05 2001-08-07 Idun Pharmaceuticals, Inc. Rapid methods for identifying modifiers of cellular apoptosis activity
US6511829B1 (en) * 1997-10-09 2003-01-28 The Regents Of The University Of California GFP-annexin fusion proteins
EP0928968A1 (fr) * 1998-01-12 1999-07-14 Universität Basel Méthode pour le screening de l'apoptose, et de la nécrose
IL123429A0 (en) 1998-02-24 1998-09-24 Nst Neurosurvival Technologies Peptides and pharmaceutical compositions comprising same
EP1520588B1 (fr) 1998-07-13 2014-12-24 Board Of Regents, The University Of Texas System L'utilisation d'anticorps vis-a-vis des aminophospholipides pour le traitement du cancer
ATE276763T1 (de) 1998-07-13 2004-10-15 Univ Texas Verwendung von antikörper gegen aminophospholipide zur krebsbehandlung
US6818213B1 (en) 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
US7067109B1 (en) 1998-07-13 2006-06-27 Board Of Regents, The University Of Texas System Cancer treatment kits comprising therapeutic conjugates that bind to aminophospholipids
US6406693B1 (en) 1998-07-13 2002-06-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
IL131266A0 (en) 1999-08-05 2001-01-28 N S T Neurosurvival Technologi Peptides and pharmaceutical compositions comprising same
WO2000010673A1 (fr) * 1998-08-24 2000-03-02 Nst Neurosurvival Technologies Ltd. Appareil et procede pour la capture de particules par exposition en surface de phospholipides anioniques de fluides biologiques
IL125908A (en) 1998-08-24 2005-05-17 Nst Neurosurvival Technologies Peptides and pharmaceutical compositions comprising same
US5939267A (en) * 1998-08-31 1999-08-17 Wayne State University Methods for the temporal analysis of programmed cell death in living cells
US6063580A (en) * 1998-08-31 2000-05-16 Wayne State University Methods for the temporal analysis of programmed cell death in living cells
AU1465801A (en) * 1999-11-03 2001-05-14 Oncotech, Inc. Methods for cancer prognosis and diagnosis
EP1118334A1 (fr) * 2000-01-11 2001-07-25 Aventis Behring Gesellschaft mit beschränkter Haftung Préparation de conjugués pour le traitement des allergies et maladies autoimmunitaires
FR2809181B1 (fr) * 2000-05-16 2002-10-25 Biocytex Monoreactif pour le dosage des microparticules plaquettaires
EP1223429A1 (fr) * 2001-01-13 2002-07-17 Dentognostics GmbH Méthode pour la détection de micro-organismes vivants
JP2004535375A (ja) 2001-04-03 2004-11-25 テセウス イメージング コーポレーション 生体内における細胞死の検出および随伴する症状の治療のためのアネキシンの使用方法
US20050013778A1 (en) * 2001-04-03 2005-01-20 Theseus Imaging Corporation Methods and compositions for predicting the response to a therapeutic regimen in a subject having a disease associated with cell death
EP1381839A4 (fr) 2001-04-03 2005-10-12 Univ Leland Stanford Junior Imagerie in-vivo de l'apoptose
AU2003216139B2 (en) * 2002-02-01 2008-08-14 Promega Corporation Bioluminescent protease assay
AU2003218025A1 (en) * 2002-03-08 2003-09-22 Michael S. Kopreski Analysis of apoptotic bodies in bodily fluids
US7179616B1 (en) 2002-10-07 2007-02-20 University Of Notre Dame Du Lac Method for detecting phosphatidylserine on the surface of cells
JP2006517227A (ja) * 2003-01-30 2006-07-20 ザ・ジェネラル・ホスピタル・コーポレイション 免疫細胞活性を調節する組成物およびその検出方法
US20040203069A1 (en) * 2003-04-10 2004-10-14 Chris Reutelingsperger Method for determining and/or isolating lipid-binding compounds
WO2005014801A1 (fr) * 2003-08-04 2005-02-17 University Court Of The University Of Edinburgh Ameliorations apportees a la productivite de cultures cellulaires
US7553632B2 (en) 2004-01-22 2009-06-30 Promega Corporation Luminogenic and nonluminogenic multiplex assay
US7416854B2 (en) * 2004-01-22 2008-08-26 Promega Corporation Luminogenic and nonluminogenic multiplex assay
US7511016B2 (en) * 2004-07-07 2009-03-31 Mosamedix B.V. Annexins, derivatives thereof, and annexin-cys variants, as well as therapeutic and diagnostic uses thereof
EP1771572B1 (fr) * 2004-07-14 2008-10-15 Janssen Pharmaceutica N.V. Test de criblage de p75ntr pour identifier des modulateurs de l'apoptose
GB0425324D0 (en) * 2004-11-17 2004-12-22 Univ Edinburgh Assay method
US7687243B1 (en) 2005-06-06 2010-03-30 Crook Tonia M Automated method for detecting apoptosis in cells
US20070048812A1 (en) * 2005-09-01 2007-03-01 Moravec Richard A Cell-based luminogenic and nonluminogenic proteasome assays
EP1960780A4 (fr) * 2005-10-31 2008-12-17 Cedars Sinai Medical Center Procede d'agglutination pour la detection rapide, l'isolement et la quantification de cellules apoptotiques
KR100987547B1 (ko) * 2006-06-01 2010-10-12 가톨릭대학교 산학협력단 냉동보관된 제대혈 줄기세포로부터 초기 세포사를 측정하는조성물, 키트 및 그 방법
US20070293893A1 (en) * 2006-06-14 2007-12-20 Craig Stolen Method and apparatus for preconditioning of cells
EP2142665B1 (fr) 2007-04-13 2013-11-27 Promega Corporation Dosage de cellules vivantes et mortes par luminescence
EP2349321B1 (fr) 2008-10-17 2020-04-22 London Health Sciences Centre Research Inc. Annexine et son utilisation pour le traitement de troubles inflammatoires
US20140235495A1 (en) 2011-09-23 2014-08-21 Siemens Healthcare Diagnostics Inc. Cell response assay for cancer and methods of producing and using same
US12031891B2 (en) 2017-12-29 2024-07-09 Hoffman-La Roche, Inc. Tissue sample preparation system
CN116773805A (zh) * 2022-03-10 2023-09-19 南方科技大学 一种试剂盒、以及细胞损伤程度的检测方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5627036A (en) * 1989-12-27 1997-05-06 Boehringer Ingelheim International Gmbh Use of an anticoagulant as a diagnostic agent
DE59010815D1 (de) * 1989-12-27 1998-04-23 Boehringer Ingelheim Int Verwendung eines antikoagulant als diagnostikum

Also Published As

Publication number Publication date
ATE160875T1 (de) 1997-12-15
CA2185535C (fr) 2000-10-24
NZ283171A (en) 1998-02-26
DE69501161T2 (de) 1998-03-19
DE69501161D1 (de) 1998-01-15
JP2824155B2 (ja) 1998-11-11
AU689248B2 (en) 1998-03-26
AU2114195A (en) 1995-10-30
NO964308D0 (no) 1996-10-10
DK0755516T3 (da) 1998-08-10
JPH09505894A (ja) 1997-06-10
WO1995027903A1 (fr) 1995-10-19
ES2112057T3 (es) 1998-03-16
EP0755516A1 (fr) 1997-01-29
US5834196A (en) 1998-11-10
NO964308L (no) 1996-12-11
CA2185535A1 (fr) 1995-10-19
EP0755516B1 (fr) 1997-12-03

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