NO307827B1 - Benzoksazol- og pyridinderivater, anvendelse av dem og farmasøytisk preparat inneholdende dem - Google Patents
Benzoksazol- og pyridinderivater, anvendelse av dem og farmasøytisk preparat inneholdende demInfo
- Publication number
- NO307827B1 NO307827B1 NO970373A NO970373A NO307827B1 NO 307827 B1 NO307827 B1 NO 307827B1 NO 970373 A NO970373 A NO 970373A NO 970373 A NO970373 A NO 970373A NO 307827 B1 NO307827 B1 NO 307827B1
- Authority
- NO
- Norway
- Prior art keywords
- benzoxazole
- pharmaceutical preparations
- preparations containing
- pyridine derivatives
- pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9415330A GB9415330D0 (en) | 1994-07-29 | 1994-07-29 | Novel compounds |
| GBGB9425599.9A GB9425599D0 (en) | 1994-12-19 | 1994-12-19 | Novel compounds |
| GBGB9509923.0A GB9509923D0 (en) | 1995-05-17 | 1995-05-17 | Novel compounds |
| PCT/GB1995/001323 WO1996004261A1 (fr) | 1994-07-29 | 1995-06-07 | Benzoxoazoles et derives de pryridine destines a etre utilises pour le traitement du diabete tardif |
| PCT/EP1995/003038 WO1996004260A1 (fr) | 1994-07-29 | 1995-07-28 | Benzoxazoles et derives de pyridine utiles dans le traitement du diabete de type ii |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO970373D0 NO970373D0 (no) | 1997-01-28 |
| NO970373L NO970373L (no) | 1997-03-18 |
| NO307827B1 true NO307827B1 (no) | 2000-06-05 |
Family
ID=27267309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO970373A NO307827B1 (no) | 1994-07-29 | 1997-01-28 | Benzoksazol- og pyridinderivater, anvendelse av dem og farmasøytisk preparat inneholdende dem |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0772605A1 (fr) |
| AP (1) | AP776A (fr) |
| BR (1) | BR9508468A (fr) |
| CA (1) | CA2196079A1 (fr) |
| CZ (1) | CZ25497A3 (fr) |
| DZ (1) | DZ1916A1 (fr) |
| FI (1) | FI970357L (fr) |
| HU (1) | HUT76637A (fr) |
| IL (3) | IL125525A (fr) |
| MA (1) | MA23632A1 (fr) |
| MX (1) | MX9700763A (fr) |
| NO (1) | NO307827B1 (fr) |
| OA (1) | OA10470A (fr) |
| PL (1) | PL318766A1 (fr) |
| SK (1) | SK12297A3 (fr) |
| WO (2) | WO1996004261A1 (fr) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9600464D0 (en) * | 1996-01-09 | 1996-03-13 | Smithkline Beecham Plc | Novel method |
| RU2169141C2 (ru) * | 1996-04-04 | 2001-06-20 | Санкио Компани Лимитед | Производные фенилалкилкарбоновой кислоты и фармацевтическая композиция на их основе |
| US6090839A (en) * | 1996-12-23 | 2000-07-18 | Merck & Co., Inc. | Antidiabetic agents |
| US6160000A (en) * | 1996-12-23 | 2000-12-12 | Merck & Co., Inc. | Antidiabetic agents based on aryl and heteroarylacetic acids |
| PL339660A1 (en) | 1997-10-02 | 2001-01-02 | Sankyo Co | Derivatives of amidocarboxylic acids |
| BR9812772A (pt) | 1997-10-27 | 2000-10-10 | Reddy Research Foundation | "compostos tricìclicos inéditos e o seu emprego na medicina;processo para a sua preparação e composições farmacêuticas contendo os mesmos" |
| CA2307068C (fr) | 1997-10-27 | 2007-04-10 | Dr. Reddy's Laboratories Limited | Composes bicycliques, procede de preparation et compositions pharmaceutiques les contenant |
| EP1124807A1 (fr) * | 1997-10-27 | 2001-08-22 | Dr. Reddy's Research Foundation | Nouvelles compositions heterocycliques et leur utilisation en medecine; procedes de leur fabrication et compositions pharmaceutiques les contenant |
| US6265401B1 (en) | 1997-10-27 | 2001-07-24 | Reddy-Cheminor, Inc. | Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| WO1999019313A1 (fr) * | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Nouveaux composes tricycliques et leur utilisation en medecine, procede de preparation de ces derniers et compositions pharmaceutiques les contenant |
| US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| US6444816B1 (en) | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
| US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| JP2002507543A (ja) * | 1998-05-27 | 2002-03-12 | ドクター・レディーズ・リサーチ・ファウンデーション | 二環系化合物、その製造方法およびそれらを含有する薬学的組成物 |
| EE200100155A (et) | 1998-09-17 | 2002-08-15 | Bristol-Myers Squibb Company | Ateroskleroosi ravimeetod, kasutades aP2 inhibiitorit ja selle kombinatsiooni |
| US6468996B1 (en) | 1998-10-21 | 2002-10-22 | Novo Nordisk A/S | Substituted hetero-polycyclic compounds as PPARα and PPARγ activators |
| WO2000023416A1 (fr) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | Nouveaux composes, leur preparation et leur utilisation |
| US6300339B1 (en) | 1998-10-21 | 2001-10-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| WO2000023445A1 (fr) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | Nouveaux composes, leur preparation et leur utilisation |
| EP1123269A1 (fr) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | Nouveaux composes, leur preparation et leur utilisation |
| US6365586B1 (en) | 1998-10-21 | 2002-04-02 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU6190199A (en) * | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
| WO2000023425A1 (fr) * | 1998-10-21 | 2000-04-27 | Novo Nordisk A/S | Nouveaux composes, preparation et utilisation correspondantes |
| EP1123297A1 (fr) * | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | Nouveaux composes, leur preparation et leur utilisation |
| US6214820B1 (en) | 1998-10-21 | 2001-04-10 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6248781B1 (en) | 1998-10-21 | 2001-06-19 | Novo Nordisk A/S | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) |
| US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
| UA60386C2 (uk) * | 1998-10-29 | 2003-10-15 | Reddys Laboratories Ltd | Спосіб одержання похідних 3-[4-[2-(феноксазин-10-іл)метокси]феніл]пропіонової кислоти (варіанти) та проміжні сполуки для їх отримання |
| WO2000063189A1 (fr) * | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Formes cristallines de r-guanidines, d'arginine ou de (l)-arginine (2s-2-ethoxy-3-{4-[2-(10h-phenoxazin-10-yl)ethoxy]phenyl}propanoate |
| US6274608B1 (en) | 1999-04-20 | 2001-08-14 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6972294B1 (en) | 1999-04-20 | 2005-12-06 | Novo Nordisk, A/S | Compounds, their preparation and use |
| US7414128B2 (en) | 1999-04-20 | 2008-08-19 | Dr. Reddy's Laboratories, Limited | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate |
| EP1171431A1 (fr) * | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Composes, leur preparation et utilisation |
| JP2002542246A (ja) | 1999-04-20 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | 新規な化合物、それらの製造及び使用 |
| HUP0200807A3 (en) * | 1999-04-20 | 2003-03-28 | Novo Nordisk As | Substituted propionic acid derivatives, process for their preparation, pharmaceutical compositions containing them and their use |
| US6369055B1 (en) | 1999-04-20 | 2002-04-09 | Novo Nordisk A/S | Compounds, their preparation and use |
| EP1175412A1 (fr) | 1999-04-28 | 2002-01-30 | Dr. Reddy's Research Foundation | Heterocycles bicycliques substitues, procede pour leur preparation et leur utilisation comme agents contre l'obesite et comme agents hypocholesterolemiques |
| WO2001016120A1 (fr) | 1999-08-27 | 2001-03-08 | Eli Lilly And Company | Derives de biaryl-oxa(thia)zole et leur utilisation en tant que modulateurs de ppar |
| ES2449194T3 (es) * | 2000-01-19 | 2014-03-18 | Cadila Healthcare Limited | Compuestos que tienen actividades hipolipidémica e hipocolesterolémica, procedimiento para su preparación y composiciones farmacéuticas que los contienen |
| US6555577B1 (en) | 2000-01-28 | 2003-04-29 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
| PL357017A1 (en) * | 2000-01-28 | 2004-07-12 | Novo Nordisk A/S | Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity |
| US6509374B2 (en) | 2000-04-17 | 2003-01-21 | Novo Nordisk A/S | Compounds, their preparation and use |
| US6908908B2 (en) | 2000-05-12 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4H-benzo [1,4] oxazin-3-ones |
| WO2001087860A2 (fr) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Nouveaux benzoxazinones utilises comme modulateurs du recepteur gamma active de la proliferation des peroxysomes, et methode de traitement associee |
| AU2001263083A1 (en) | 2000-05-12 | 2001-11-26 | Ortho-Mcneil Pharmaceutical, Inc. | Biologically active 4h-benzo(1,4)oxazin-3-ones |
| WO2001087861A2 (fr) * | 2000-05-12 | 2001-11-22 | Ortho-Mcneil Pharmaceutical, Inc. | Methodes de traitement mettant en oeuvre des benzoxazinones comme modulateurs du recepteur gamma active par le proliferateur du peroxisome |
| US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
| US6869967B2 (en) | 2001-07-30 | 2005-03-22 | Novo Nordisk A/S | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives |
| US7067530B2 (en) | 2001-07-30 | 2006-06-27 | Novo Nordisk A/S | Compounds, their preparation and use |
| US7220877B2 (en) | 2001-10-17 | 2007-05-22 | Novo Nordisk A/S | Compounds, their preparation and use |
| AU2002351752A1 (en) | 2001-12-29 | 2003-07-30 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
| US7015345B2 (en) | 2002-02-21 | 2006-03-21 | Asahi Kasei Pharma Corporation | Propionic acid derivatives |
| US7816385B2 (en) | 2002-12-20 | 2010-10-19 | High Point Pharmaceuticals, Llc | Dimeric dicarboxylic acid derivatives, their preparation and use |
| US6653334B1 (en) | 2002-12-27 | 2003-11-25 | Kowa Co., Ltd. | Benzoxazole compound and pharmaceutical composition containing the same |
| EP2154131A4 (fr) * | 2007-04-26 | 2011-09-21 | Pharmafrontier Co Ltd | Inhibiteur du récepteur couplé à protéine g et produit pharmaceutique |
| EP3009136A1 (fr) | 2011-01-31 | 2016-04-20 | Cadila Healthcare Limited | Traitement de la lipodystrophie |
| UA114360C2 (uk) | 2013-04-22 | 2017-05-25 | Каділа Хелткере Лімітед | Спосіб лікування та/або зменшення інтенсивності неалкогольної жирової хвороби печінки (нжхп) |
| US20160107989A1 (en) | 2013-05-30 | 2016-04-21 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
| TW201513857A (zh) | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | 協同性組成物 |
| IN2013MU02470A (fr) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
| IN2013MU02905A (fr) | 2013-09-06 | 2015-07-03 | Cadila Healthcare Ltd | |
| WO2017064635A2 (fr) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Composé pyrrole, compositions et procédé de préparation associé |
| EP3551180B1 (fr) | 2016-12-09 | 2021-09-29 | Cadila Healthcare Limited | Traitement de la cholangite biliaire primitive |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
| SK695A3 (en) * | 1992-07-03 | 1995-07-11 | Smithkline Beecham Plc | Heterocyclic compounds method of their production and using |
-
1995
- 1995-06-07 WO PCT/GB1995/001323 patent/WO1996004261A1/fr not_active Ceased
- 1995-06-07 BR BR9508468A patent/BR9508468A/pt unknown
- 1995-07-26 DZ DZ950094A patent/DZ1916A1/fr active
- 1995-07-27 IL IL12552595A patent/IL125525A/xx unknown
- 1995-07-27 IL IL11475995A patent/IL114759A/xx unknown
- 1995-07-27 MA MA23972A patent/MA23632A1/fr unknown
- 1995-07-28 HU HU9700264A patent/HUT76637A/hu unknown
- 1995-07-28 CZ CZ97254A patent/CZ25497A3/cs unknown
- 1995-07-28 CA CA002196079A patent/CA2196079A1/fr not_active Abandoned
- 1995-07-28 MX MX9700763A patent/MX9700763A/es unknown
- 1995-07-28 AP APAP/P/1997/000918A patent/AP776A/en active
- 1995-07-28 SK SK122-97A patent/SK12297A3/sk unknown
- 1995-07-28 WO PCT/EP1995/003038 patent/WO1996004260A1/fr not_active Ceased
- 1995-07-28 FI FI970357A patent/FI970357L/fi unknown
- 1995-07-28 EP EP95930436A patent/EP0772605A1/fr not_active Withdrawn
- 1995-07-28 PL PL95318766A patent/PL318766A1/xx unknown
-
1997
- 1997-01-28 NO NO970373A patent/NO307827B1/no not_active IP Right Cessation
- 1997-01-29 OA OA60957A patent/OA10470A/en unknown
-
1998
- 1998-07-27 IL IL12552598A patent/IL125525A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI970357A0 (fi) | 1997-01-28 |
| MA23632A1 (fr) | 1996-04-01 |
| CA2196079A1 (fr) | 1996-02-15 |
| OA10470A (en) | 2002-04-08 |
| NO970373D0 (no) | 1997-01-28 |
| HUT76637A (en) | 1997-10-28 |
| CZ25497A3 (en) | 1997-09-17 |
| SK12297A3 (en) | 1997-08-06 |
| PL318766A1 (en) | 1997-07-07 |
| AP9700918A0 (en) | 1997-01-31 |
| DZ1916A1 (fr) | 2002-02-17 |
| FI970357A7 (fi) | 1997-03-26 |
| AP776A (en) | 1999-10-28 |
| IL114759A0 (en) | 1995-12-31 |
| IL114759A (en) | 1999-10-28 |
| WO1996004260A1 (fr) | 1996-02-15 |
| WO1996004261A1 (fr) | 1996-02-15 |
| NO970373L (no) | 1997-03-18 |
| EP0772605A1 (fr) | 1997-05-14 |
| MX9700763A (es) | 1997-05-31 |
| FI970357L (fi) | 1997-03-26 |
| BR9508468A (pt) | 1997-11-25 |
| IL125525A0 (en) | 1999-03-12 |
| IL125525A (en) | 2000-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JANUARY 2003 |