OA10470A - Benzoxazoles and pyridine derivates useful in the treatment of the type ii diabetes - Google Patents

Benzoxazoles and pyridine derivates useful in the treatment of the type ii diabetes Download PDF

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Publication number
OA10470A
OA10470A OA60957A OA60957A OA10470A OA 10470 A OA10470 A OA 10470A OA 60957 A OA60957 A OA 60957A OA 60957 A OA60957 A OA 60957A OA 10470 A OA10470 A OA 10470A
Authority
OA
OAPI
Prior art keywords
formula
compound
pharmaceutically acceptable
benzoxazolyl
ethoxy
Prior art date
Application number
OA60957A
Other languages
English (en)
Inventor
Harshad Kantilal Rami
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415330A external-priority patent/GB9415330D0/en
Priority claimed from GBGB9425599.9A external-priority patent/GB9425599D0/en
Priority claimed from GBGB9509923.0A external-priority patent/GB9509923D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of OA10470A publication Critical patent/OA10470A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
OA60957A 1994-07-29 1997-01-29 Benzoxazoles and pyridine derivates useful in the treatment of the type ii diabetes OA10470A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9415330A GB9415330D0 (en) 1994-07-29 1994-07-29 Novel compounds
GBGB9425599.9A GB9425599D0 (en) 1994-12-19 1994-12-19 Novel compounds
GBGB9509923.0A GB9509923D0 (en) 1995-05-17 1995-05-17 Novel compounds
PCT/GB1995/001323 WO1996004261A1 (fr) 1994-07-29 1995-06-07 Benzoxoazoles et derives de pryridine destines a etre utilises pour le traitement du diabete tardif

Publications (1)

Publication Number Publication Date
OA10470A true OA10470A (en) 2002-04-08

Family

ID=27267309

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60957A OA10470A (en) 1994-07-29 1997-01-29 Benzoxazoles and pyridine derivates useful in the treatment of the type ii diabetes

Country Status (16)

Country Link
EP (1) EP0772605A1 (fr)
AP (1) AP776A (fr)
BR (1) BR9508468A (fr)
CA (1) CA2196079A1 (fr)
CZ (1) CZ25497A3 (fr)
DZ (1) DZ1916A1 (fr)
FI (1) FI970357L (fr)
HU (1) HUT76637A (fr)
IL (3) IL125525A (fr)
MA (1) MA23632A1 (fr)
MX (1) MX9700763A (fr)
NO (1) NO307827B1 (fr)
OA (1) OA10470A (fr)
PL (1) PL318766A1 (fr)
SK (1) SK12297A3 (fr)
WO (2) WO1996004261A1 (fr)

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WO1999019313A1 (fr) * 1997-10-27 1999-04-22 Dr. Reddy's Research Foundation Nouveaux composes tricycliques et leur utilisation en medecine, procede de preparation de ces derniers et compositions pharmaceutiques les contenant
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US6468996B1 (en) 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
WO2000023416A1 (fr) * 1998-10-21 2000-04-27 Novo Nordisk A/S Nouveaux composes, leur preparation et leur utilisation
US6300339B1 (en) 1998-10-21 2001-10-09 Novo Nordisk A/S Compounds, their preparation and use
WO2000023445A1 (fr) * 1998-10-21 2000-04-27 Novo Nordisk A/S Nouveaux composes, leur preparation et leur utilisation
EP1123269A1 (fr) * 1998-10-21 2001-08-16 Novo Nordisk A/S Nouveaux composes, leur preparation et leur utilisation
US6365586B1 (en) 1998-10-21 2002-04-02 Novo Nordisk A/S Compounds, their preparation and use
AU6190199A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
WO2000023425A1 (fr) * 1998-10-21 2000-04-27 Novo Nordisk A/S Nouveaux composes, preparation et utilisation correspondantes
EP1123297A1 (fr) * 1998-10-21 2001-08-16 Novo Nordisk A/S Nouveaux composes, leur preparation et leur utilisation
US6214820B1 (en) 1998-10-21 2001-04-10 Novo Nordisk A/S Compounds, their preparation and use
US6248781B1 (en) 1998-10-21 2001-06-19 Novo Nordisk A/S Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
UA60386C2 (uk) * 1998-10-29 2003-10-15 Reddys Laboratories Ltd Спосіб одержання похідних 3-[4-[2-(феноксазин-10-іл)метокси]феніл]пропіонової кислоти (варіанти) та проміжні сполуки для їх отримання
WO2000063189A1 (fr) * 1999-04-16 2000-10-26 Novo Nordisk A/S Formes cristallines de r-guanidines, d'arginine ou de (l)-arginine (2s-2-ethoxy-3-{4-[2-(10h-phenoxazin-10-yl)ethoxy]phenyl}propanoate
US6274608B1 (en) 1999-04-20 2001-08-14 Novo Nordisk A/S Compounds, their preparation and use
US6972294B1 (en) 1999-04-20 2005-12-06 Novo Nordisk, A/S Compounds, their preparation and use
US7414128B2 (en) 1999-04-20 2008-08-19 Dr. Reddy's Laboratories, Limited Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate
EP1171431A1 (fr) * 1999-04-20 2002-01-16 Novo Nordisk A/S Composes, leur preparation et utilisation
JP2002542246A (ja) 1999-04-20 2002-12-10 ノボ ノルディスク アクティーゼルスカブ 新規な化合物、それらの製造及び使用
HUP0200807A3 (en) * 1999-04-20 2003-03-28 Novo Nordisk As Substituted propionic acid derivatives, process for their preparation, pharmaceutical compositions containing them and their use
US6369055B1 (en) 1999-04-20 2002-04-09 Novo Nordisk A/S Compounds, their preparation and use
EP1175412A1 (fr) 1999-04-28 2002-01-30 Dr. Reddy's Research Foundation Heterocycles bicycliques substitues, procede pour leur preparation et leur utilisation comme agents contre l'obesite et comme agents hypocholesterolemiques
WO2001016120A1 (fr) 1999-08-27 2001-03-08 Eli Lilly And Company Derives de biaryl-oxa(thia)zole et leur utilisation en tant que modulateurs de ppar
ES2449194T3 (es) * 2000-01-19 2014-03-18 Cadila Healthcare Limited Compuestos que tienen actividades hipolipidémica e hipocolesterolémica, procedimiento para su preparación y composiciones farmacéuticas que los contienen
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EP2154131A4 (fr) * 2007-04-26 2011-09-21 Pharmafrontier Co Ltd Inhibiteur du récepteur couplé à protéine g et produit pharmaceutique
EP3009136A1 (fr) 2011-01-31 2016-04-20 Cadila Healthcare Limited Traitement de la lipodystrophie
UA114360C2 (uk) 2013-04-22 2017-05-25 Каділа Хелткере Лімітед Спосіб лікування та/або зменшення інтенсивності неалкогольної жирової хвороби печінки (нжхп)
US20160107989A1 (en) 2013-05-30 2016-04-21 Cadila Healthcare Limited A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
TW201513857A (zh) 2013-07-05 2015-04-16 Cadila Healthcare Ltd 協同性組成物
IN2013MU02470A (fr) 2013-07-25 2015-06-26 Cadila Healthcare Ltd
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US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
SK695A3 (en) * 1992-07-03 1995-07-11 Smithkline Beecham Plc Heterocyclic compounds method of their production and using

Also Published As

Publication number Publication date
FI970357A0 (fi) 1997-01-28
MA23632A1 (fr) 1996-04-01
CA2196079A1 (fr) 1996-02-15
NO970373D0 (no) 1997-01-28
HUT76637A (en) 1997-10-28
NO307827B1 (no) 2000-06-05
CZ25497A3 (en) 1997-09-17
SK12297A3 (en) 1997-08-06
PL318766A1 (en) 1997-07-07
AP9700918A0 (en) 1997-01-31
DZ1916A1 (fr) 2002-02-17
FI970357A7 (fi) 1997-03-26
AP776A (en) 1999-10-28
IL114759A0 (en) 1995-12-31
IL114759A (en) 1999-10-28
WO1996004260A1 (fr) 1996-02-15
WO1996004261A1 (fr) 1996-02-15
NO970373L (no) 1997-03-18
EP0772605A1 (fr) 1997-05-14
MX9700763A (es) 1997-05-31
FI970357L (fi) 1997-03-26
BR9508468A (pt) 1997-11-25
IL125525A0 (en) 1999-03-12
IL125525A (en) 2000-02-29

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