NO309860B1 - Acylaminoindolderivater som 5-HT 1 agonister og farmasøytisk preparat - Google Patents

Acylaminoindolderivater som 5-HT 1 agonister og farmasøytisk preparat Download PDF

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Publication number
NO309860B1
NO309860B1 NO943803A NO943803A NO309860B1 NO 309860 B1 NO309860 B1 NO 309860B1 NO 943803 A NO943803 A NO 943803A NO 943803 A NO943803 A NO 943803A NO 309860 B1 NO309860 B1 NO 309860B1
Authority
NO
Norway
Prior art keywords
alkyl
aryl
compound
compounds
compound according
Prior art date
Application number
NO943803A
Other languages
English (en)
Norwegian (no)
Other versions
NO943803D0 (no
NO943803L (no
Inventor
John Eugene Macor
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO943803D0 publication Critical patent/NO943803D0/no
Publication of NO943803L publication Critical patent/NO943803L/no
Publication of NO309860B1 publication Critical patent/NO309860B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Soft Magnetic Materials (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Pyrrole Compounds (AREA)
NO943803A 1992-04-10 1994-10-07 Acylaminoindolderivater som 5-HT 1 agonister og farmasøytisk preparat NO309860B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86638292A 1992-04-10 1992-04-10
PCT/US1993/001807 WO1993021180A1 (en) 1992-04-10 1993-03-04 Acylaminoindole derivatives as 5-ht1 agonists

Publications (3)

Publication Number Publication Date
NO943803D0 NO943803D0 (no) 1994-10-07
NO943803L NO943803L (no) 1994-10-07
NO309860B1 true NO309860B1 (no) 2001-04-09

Family

ID=25347493

Family Applications (1)

Application Number Title Priority Date Filing Date
NO943803A NO309860B1 (no) 1992-04-10 1994-10-07 Acylaminoindolderivater som 5-HT 1 agonister og farmasøytisk preparat

Country Status (31)

Country Link
US (1) US5498626A (de)
EP (1) EP0635015B1 (de)
JP (1) JP2544704B2 (de)
KR (1) KR0179074B1 (de)
CN (1) CN1038506C (de)
AT (1) ATE148465T1 (de)
AU (1) AU670270B2 (de)
BR (1) BR9306221A (de)
CA (1) CA2132706C (de)
CZ (1) CZ282653B6 (de)
DE (1) DE69307875T2 (de)
DK (1) DK0635015T3 (de)
EG (1) EG20466A (de)
ES (1) ES2097496T3 (de)
FI (2) FI111256B (de)
GR (1) GR3022767T3 (de)
HR (1) HRP930753B1 (de)
HU (1) HUT64060A (de)
IL (1) IL105309A0 (de)
MX (1) MX9301996A (de)
MY (1) MY115278A (de)
NO (1) NO309860B1 (de)
NZ (1) NZ251047A (de)
PL (1) PL172232B1 (de)
RU (1) RU2110516C1 (de)
SK (1) SK278182B6 (de)
TW (1) TW394769B (de)
UA (1) UA34452C2 (de)
WO (1) WO1993021180A1 (de)
YU (1) YU48916B (de)
ZA (1) ZA932536B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
SK280193B6 (sk) 1992-04-07 1999-09-10 Pfizer Inc. Indolové deriváty predstavujúce 5-ht1 agonisty, fa
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
DK0716649T3 (da) * 1993-08-31 1999-02-08 Pfizer 5-Arylindolderivater
GB9402011D0 (en) * 1994-02-02 1994-03-30 Merck Sharp & Dohme Therapeutic agents
GB9402016D0 (en) * 1994-02-02 1994-03-30 Merck Sharp & Dohme Therapeutic agents
FI971334A7 (fi) * 1994-08-03 1997-04-01 Asta Medica Ag Indoli-, indatsoli-, pyridopyrroli- ja pyridopyratsolijohdannaiset, jo illa on antiastmaattinen, antiallerginen, anti-inflammatorinen ja immu nomoduloiva vaikutus
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
GB9420503D0 (en) * 1994-10-11 1994-11-23 Pfizer Ltd Therapeutic agents
GB9420529D0 (en) 1994-10-12 1994-11-30 Pfizer Ltd Indoles
AU3170099A (en) * 1998-04-16 1999-11-08 Yamanouchi Pharmaceutical Co., Ltd. Remedies for obesity
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
JP2006516286A (ja) * 2003-01-22 2006-06-29 ジーティーエックス・インコーポレイテッド Ｓａｒｍによる女性のアンドロゲン減少に関連する病気の治療
CN101939306A (zh) * 2007-12-07 2011-01-05 美国辉瑞有限公司 反式-n-异丁基-3-氟-3-[3-氟-4-(吡咯烷-1-基-甲基)-苯基]环丁烷甲酰胺的甲苯磺酸盐
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
CN103408535B (zh) * 2013-08-13 2016-03-02 张家港威胜生物医药有限公司 一种依来曲普坦中间体-5-溴-3-(n-甲基吡咯啉-2-基甲基)-1h-吲哚合成工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
NL8103764A (nl) * 1980-08-12 1982-03-01 Glaxo Group Ltd Heterocyclische verbindingen, werkwijze ter bereiding daarvan, alsmede farmaceutische preparaten die deze verbindingen als actieve component bevatten.
ZA815541B (en) * 1980-08-12 1983-03-30 Glaxo Group Ltd Heterocyclic compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
IL96891A0 (en) * 1990-01-17 1992-03-29 Merck Sharp & Dohme Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
PT97888B (pt) * 1990-06-07 1998-12-31 Zeneca Ltd Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem
PL170330B1 (pl) * 1990-10-15 1996-11-29 Pfizer Sposób wytwarzania nowych pochodnych indolu PL PL PL PL PL PL
US5208248A (en) * 1991-01-11 1993-05-04 Merck Sharpe & Dohme, Ltd. Indazole-substituted five-membered heteroaromatic compounds
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
BR9206810A (pt) * 1991-11-25 1995-10-31 Pfizer Derivados de indol

Also Published As

Publication number Publication date
EP0635015B1 (de) 1997-01-29
MY115278A (en) 2003-05-31
UA34452C2 (uk) 2001-03-15
FI931613L (fi) 1993-10-11
US5498626A (en) 1996-03-12
ES2097496T3 (es) 1997-04-01
TW394769B (en) 2000-06-21
CZ282653B6 (cs) 1997-08-13
IL105309A0 (en) 1993-08-18
HU9301048D0 (en) 1993-06-28
DK0635015T3 (da) 1997-03-17
HRP930753B1 (en) 2000-10-31
RU94045902A (ru) 1996-08-27
WO1993021180A1 (en) 1993-10-28
DE69307875D1 (de) 1997-03-13
EP0635015A1 (de) 1995-01-25
FI931613A0 (fi) 1993-04-08
SK278182B6 (en) 1996-03-06
JPH07501831A (ja) 1995-02-23
ATE148465T1 (de) 1997-02-15
FI20010214L (fi) 2001-02-05
BR9306221A (pt) 1998-06-30
CA2132706C (en) 1998-08-04
CA2132706A1 (en) 1993-10-28
PL172232B1 (pl) 1997-08-29
NO943803D0 (no) 1994-10-07
YU25593A (sh) 1996-10-09
KR950700903A (ko) 1995-02-20
NO943803L (no) 1994-10-07
CZ247794A3 (en) 1995-07-12
ZA932536B (en) 1994-10-08
NZ251047A (en) 1996-09-25
DE69307875T2 (de) 1997-05-22
FI20010214A7 (fi) 2001-02-05
KR0179074B1 (ko) 1999-03-20
HUT64060A (en) 1993-11-29
CN1080288A (zh) 1994-01-05
EG20466A (en) 1999-05-31
FI111256B (fi) 2003-06-30
RU2110516C1 (ru) 1998-05-10
AU670270B2 (en) 1996-07-11
YU48916B (sh) 2002-11-15
HRP930753A2 (en) 1994-10-31
AU3782193A (en) 1993-11-18
GR3022767T3 (en) 1997-06-30
MX9301996A (es) 1994-03-31
CN1038506C (zh) 1998-05-27
JP2544704B2 (ja) 1996-10-16
SK120794A3 (en) 1995-05-10

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