NO313985B1 - Anvendelse av Ara-C-derivater til fremstilling av farmasöytiske preparatertil behandling av solide tumorer og lymfomer, samt nye Ara-C-derivater og farmasöytiske blandinger som omfatter disse - Google Patents

Anvendelse av Ara-C-derivater til fremstilling av farmasöytiske preparatertil behandling av solide tumorer og lymfomer, samt nye Ara-C-derivater og farmasöytiske blandinger som omfatter disse

Info

Publication number: NO313985B1
Authority: NO; Norway
Prior art keywords: ara; treatment; preparation; elaidate; derivatives
Prior art date: 1995-07-25

Application number

NO19980296A

Other languages

English (en)

Norwegian (no)

Other versions

NO980296L (no

NO980296D0 (no

Inventor

Finn Myhren

Bernt Boerretzen

Are Dalen

Kjell Torgeir Stokke

Original Assignee

Conpharma As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-25

Filing date

1998-01-23

Publication date

2003-01-13

1998-01-23 Application filed by Conpharma As filed Critical Conpharma As

1998-01-23 Priority to NO19980296A priority Critical patent/NO313985B1/no

1998-01-23 Publication of NO980296L publication Critical patent/NO980296L/no

1998-01-23 Publication of NO980296D0 publication Critical patent/NO980296D0/no

2003-01-13 Publication of NO313985B1 publication Critical patent/NO313985B1/no

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Hematology (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Artificial Filaments (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Polyamides (AREA)

NO19980296A 1995-07-25 1998-01-23 Anvendelse av Ara-C-derivater til fremstilling av farmasöytiske preparatertil behandling av solide tumorer og lymfomer, samt nye Ara-C-derivater og farmasöytiske blandinger som omfatter disse NO313985B1 (no)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
NO19980296A NO313985B1 (no)	1995-07-25	1998-01-23	Anvendelse av Ara-C-derivater til fremstilling av farmasöytiske preparatertil behandling av solide tumorer og lymfomer, samt nye Ara-C-derivater og farmasöytiske blandinger som omfatter disse

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9515279.9A GB9515279D0 (en)	1995-07-25	1995-07-25	Improved therapeutic agents
PCT/NO1996/000179 WO1997005154A1 (en)	1995-07-25	1996-07-12	Improved therapeutic agents
NO19980296A NO313985B1 (no)	1995-07-25	1998-01-23	Anvendelse av Ara-C-derivater til fremstilling av farmasöytiske preparatertil behandling av solide tumorer og lymfomer, samt nye Ara-C-derivater og farmasöytiske blandinger som omfatter disse

Publications (3)

Publication Number	Publication Date
NO980296L NO980296L (no)	1998-01-23
NO980296D0 NO980296D0 (no)	1998-01-23
NO313985B1 true NO313985B1 (no)	2003-01-13

Family

ID=10778247

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19980296A NO313985B1 (no)	1995-07-25	1998-01-23	Anvendelse av Ara-C-derivater til fremstilling av farmasöytiske preparatertil behandling av solide tumorer og lymfomer, samt nye Ara-C-derivater og farmasöytiske blandinger som omfatter disse

Country Status (25)

Country	Link
US (2)	US6316425B1 (de)
EP (1)	EP0842185B1 (de)
JP (2)	JP4372227B2 (de)
KR (1)	KR100401909B1 (de)
AT (1)	ATE207076T1 (de)
AU (1)	AU714814B2 (de)
CA (1)	CA2227533C (de)
CZ (1)	CZ291612B6 (de)
DE (1)	DE69616074T2 (de)
DK (1)	DK0842185T3 (de)
ES (1)	ES2166900T3 (de)
GB (1)	GB9515279D0 (de)
HU (1)	HU224839B1 (de)
IL (2)	IL122942A0 (de)
MX (1)	MX9800622A (de)
NO (1)	NO313985B1 (de)
NZ (1)	NZ313790A (de)
PL (1)	PL183601B1 (de)
PT (1)	PT842185E (de)
RU (1)	RU2165260C2 (de)
SK (1)	SK283003B6 (de)
TW (1)	TW434251B (de)
UA (1)	UA55389C2 (de)
WO (1)	WO1997005154A1 (de)
ZA (1)	ZA966047B (de)

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US6458772B1 (en)	1909-10-07	2002-10-01	Medivir Ab	Prodrugs
JP2001503767A (ja) *	1996-11-12	2001-03-21	メディヴィル・アクチボラグ	ヌクレオシド
ATE236188T1 (de) *	1997-01-24	2003-04-15	Conpharma As	Gemcitabin-derivate
RU2207573C2 (ru) *	2001-08-27	2003-06-27	Новичков Евгений Владимирович	Способ прогнозирования продолжительности жизни больных печеночно-клеточной карциномой
US7393862B2 (en) *	2002-05-17	2008-07-01	Celgene Corporation	Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
US20070160554A1 (en) *	2003-11-03	2007-07-12	Cognis Ip Management Gmbh	Acyl ribonucleosides and acyl deoxyribonucleosides, compositions of, and methods of making same
NO324263B1 (no) *	2005-12-08	2007-09-17	Clavis Pharma Asa	Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
US8497292B2 (en)	2005-12-28	2013-07-30	Translational Therapeutics, Inc.	Translational dysfunction based therapeutics
UA99308C2 (ru) *	2007-09-26	2012-08-10	Маунт Синай Скул Оф Медсин	Аналог азацитидина и его применение
GB0808357D0 (en) *	2008-05-08	2008-06-18	Cyclacel Ltd	Process
BR112012011784A2 (pt) *	2009-11-20	2019-09-24	Clavis Pharma Asa	"formulações parenterais de derivados de gencitabina".
US8912162B2 (en)	2010-07-13	2014-12-16	Clavis Pharma Asa	Parenteral formulations of elacytarabine derivatives
AU2013241341B2 (en) *	2012-03-28	2016-09-08	Fujifilm Corporation	Salt of 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine
CN111655341A (zh)	2018-01-15	2020-09-11	长春亿诺科医药科技有限责任公司	用于恶病质的治疗

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US3894000A (en) *	1971-01-27	1975-07-08	Upjohn Co	Ara-cytidine derivatives and process of preparation
US4771056A (en) *	1985-08-29	1988-09-13	Roman Rozencwaig	Method of medical treatment with serotonin antagonists
RU2085557C1 (ru)	1991-09-30	1997-07-27	Санкио Компани Лимитед	Производные нуклеозидов пиримидина или их фармацевтически приемлемые соли и способ их получения
GB2266525A (en) *	1992-03-17	1993-11-03	Merck & Co Inc	Substituted cephalosporin sulfone compositions useful in the treatment of leukemia
GB9307043D0 (en)	1993-04-05	1993-05-26	Norsk Hydro As	Chemical compounds
US5641758A (en)	1993-11-10	1997-06-24	Kluge; Michael	Cytarabine derivatives, the preparation and use thereof

1995
- 1995-07-25 GB GBGB9515279.9A patent/GB9515279D0/en active Pending
1996
- 1996-07-12 JP JP50750497A patent/JP4372227B2/ja not_active Expired - Fee Related
- 1996-07-12 SK SK80-98A patent/SK283003B6/sk not_active IP Right Cessation
- 1996-07-12 PT PT96926032T patent/PT842185E/pt unknown
- 1996-07-12 NZ NZ313790A patent/NZ313790A/xx not_active IP Right Cessation
- 1996-07-12 RU RU98103238/04A patent/RU2165260C2/ru not_active IP Right Cessation
- 1996-07-12 CA CA002227533A patent/CA2227533C/en not_active Expired - Fee Related
- 1996-07-12 KR KR10-1998-0700463A patent/KR100401909B1/ko not_active Expired - Fee Related
- 1996-07-12 AT AT96926032T patent/ATE207076T1/de active
- 1996-07-12 US US08/983,483 patent/US6316425B1/en not_active Expired - Lifetime
- 1996-07-12 AU AU66335/96A patent/AU714814B2/en not_active Ceased
- 1996-07-12 ES ES96926032T patent/ES2166900T3/es not_active Expired - Lifetime
- 1996-07-12 WO PCT/NO1996/000179 patent/WO1997005154A1/en not_active Ceased
- 1996-07-12 DE DE69616074T patent/DE69616074T2/de not_active Expired - Lifetime
- 1996-07-12 IL IL12294296A patent/IL122942A0/xx active IP Right Grant
- 1996-07-12 HU HU9900924A patent/HU224839B1/hu not_active IP Right Cessation
- 1996-07-12 CZ CZ1998163A patent/CZ291612B6/cs not_active IP Right Cessation
- 1996-07-12 PL PL96324690A patent/PL183601B1/pl not_active IP Right Cessation
- 1996-07-12 DK DK96926032T patent/DK0842185T3/da active
- 1996-07-12 EP EP96926032A patent/EP0842185B1/de not_active Expired - Lifetime
- 1996-07-16 ZA ZA9606047A patent/ZA966047B/xx unknown
- 1996-10-02 TW TW085111996A patent/TW434251B/zh not_active IP Right Cessation
- 1996-12-07 UA UA98020922A patent/UA55389C2/uk unknown
1998
- 1998-01-15 IL IL122942A patent/IL122942A/en not_active IP Right Cessation
- 1998-01-21 MX MX9800622A patent/MX9800622A/es not_active IP Right Cessation
- 1998-01-23 NO NO19980296A patent/NO313985B1/no not_active IP Right Cessation
1999
- 1999-11-09 US US09/435,641 patent/US6335322B1/en not_active Expired - Fee Related
2009
- 2009-07-03 JP JP2009159081A patent/JP5087052B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IL122942A (en)	2006-12-10
PL324690A1 (en)	1998-06-08
KR100401909B1 (ko)	2004-02-14
JP2002504068A (ja)	2002-02-05
CZ291612B6 (cs)	2003-04-16
DE69616074T2 (de)	2002-06-06
NZ313790A (en)	1999-07-29
UA55389C2 (uk)	2003-04-15
JP4372227B2 (ja)	2009-11-25
AU6633596A (en)	1997-02-26
CA2227533A1 (en)	1997-02-13
EP0842185A1 (de)	1998-05-20
AU714814B2 (en)	2000-01-13
MX9800622A (es)	1998-11-30
RU2165260C2 (ru)	2001-04-20
EP0842185B1 (de)	2001-10-17
US6335322B1 (en)	2002-01-01
HUP9900924A2 (hu)	2001-05-28
ATE207076T1 (de)	2001-11-15
TW434251B (en)	2001-05-16
GB9515279D0 (en)	1995-09-20
ZA966047B (en)	1997-02-04
ES2166900T3 (es)	2002-05-01
NO980296L (no)	1998-01-23
IL122942A0 (en)	1999-05-09
PL183601B1 (pl)	2002-06-28
US6316425B1 (en)	2001-11-13
DK0842185T3 (da)	2002-02-04
DE69616074D1 (de)	2001-11-22
KR19990035804A (ko)	1999-05-25
HU224839B1 (en)	2006-03-28
NO980296D0 (no)	1998-01-23
HUP9900924A3 (en)	2001-06-28
CZ16398A3 (cs)	1998-06-17
SK8098A3 (en)	1998-07-08
CA2227533C (en)	2007-01-09
PT842185E (pt)	2002-04-29
WO1997005154A1 (en)	1997-02-13
JP2009215326A (ja)	2009-09-24
JP5087052B2 (ja)	2012-11-28
SK283003B6 (sk)	2003-01-09

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Date	Code	Title	Description
2014-02-24	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
JP5087052B2 (ja)	2012-11-28	改良された治療剤
KR100483256B1 (ko)	2005-04-15	젬시타빈 유도체
US20160256481A1 (en)	2016-09-08	Use of water soluble platinum complex in preparing drugs for prevention and treatment of cancers
JP2010540471A (ja)	2010-12-24	ガンボギン酸グリコシド誘導体及びアナログ、並びにその製法及び応用
US20140349955A1 (en)	2014-11-27	Use of fluorine-containing water soluble platinum complex in preparing drugs for prevention and treatment of cancers
DK166830B1 (da)	1993-07-19	5-fluor-2'-deoxyuridin-3',5'-derivater, hydrater og salte heraf, fremgangsmaade til fremstilling af disse samt antitumorpraeparater indeholdende disse derivater
Wang et al.	2017	Synthesis and evaluation of an injectable everolimus prodrug
RU2194711C2 (ru)	2002-12-20	Производные гемцитабина
GB2494595A (en)	2013-03-13	Phenylbutyryl curcumin derivatives and uses for preparing anti-tumor drugs thereof
US11173174B2 (en)	2021-11-16	DNMT inhibitor as solid tumor therapeutic drug
EP1464636A1 (de)	2004-10-06	Neue substanz mit antitumorwirkung/entzündungshemmender wirkung
JPS6316398B2 (de)	1988-04-08
NO318934B1 (no)	2005-05-30	Gemcitabinderivater
MXPA99006790A (en)	2000-01-21	Gemcitabine derivatives
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