NO314354B1 - Enantiomerrene estere, fremgangsmåte for deres fremstilling og deres anvendelse i legemidler - Google Patents

Enantiomerrene estere, fremgangsmåte for deres fremstilling og deres anvendelse i legemidler Download PDF

Info

Publication number: NO314354B1
Authority: NO; Norway
Prior art keywords: general formula; methyl; dimethyl; oxy; pyrrolidinium
Prior art date: 1996-11-11

Application number

NO19991056A

Other languages

English (en)

Norwegian (no)

Other versions

NO991056D0 (no

NO991056L (no

Inventor

Guenter Lambrecht

Michael Manfred Elgert

Sittah Czeche

Magali Waelbroeck

Original Assignee

Mutschler Ernst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-11

Filing date

1999-03-03

Publication date

2003-03-10

1999-03-03 Application filed by Mutschler Ernst filed Critical Mutschler Ernst

1999-03-03 Publication of NO991056D0 publication Critical patent/NO991056D0/no

1999-05-11 Publication of NO991056L publication Critical patent/NO991056L/no

2003-03-10 Publication of NO314354B1 publication Critical patent/NO314354B1/no

Links

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230000003285 pharmacodynamic effect Effects 0.000 description 1
235000015320 potassium carbonate Nutrition 0.000 description 1
125000001844 prenyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
210000001747 pupil Anatomy 0.000 description 1
230000010344 pupil dilation Effects 0.000 description 1
229960002290 pyridostigmine Drugs 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
230000009467 reduction Effects 0.000 description 1
230000002040 relaxant effect Effects 0.000 description 1
238000011160 research Methods 0.000 description 1
210000003296 saliva Anatomy 0.000 description 1
125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
230000008054 signal transmission Effects 0.000 description 1
229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
229910052938 sodium sulfate Inorganic materials 0.000 description 1
235000011152 sodium sulphate Nutrition 0.000 description 1
210000004243 sweat Anatomy 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
125000001973 tert-pentyl group Chemical group [H]C([H])([H])C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
238000000825 ultraviolet detection Methods 0.000 description 1
210000003932 urinary bladder Anatomy 0.000 description 1
210000004291 uterus Anatomy 0.000 description 1
210000001177 vas deferen Anatomy 0.000 description 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
229920002554 vinyl polymer Polymers 0.000 description 1
238000010626 work up procedure Methods 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)

NO19991056A 1996-11-11 1999-03-03 Enantiomerrene estere, fremgangsmåte for deres fremstilling og deres anvendelse i legemidler NO314354B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AT197396		1996-11-11
PCT/AT1997/000245 WO1998021183A1 (de)	1996-11-11	1997-11-11	Enantiomerenreine, basische aryl-cycloalkyl-hydroxycarbonsäureester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (3)

Publication Number	Publication Date
NO991056D0 NO991056D0 (no)	1999-03-03
NO991056L NO991056L (no)	1999-05-11
NO314354B1 true NO314354B1 (no)	2003-03-10

Family

ID=3525062

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19991056A NO314354B1 (no)	1996-11-11	1999-03-03	Enantiomerrene estere, fremgangsmåte for deres fremstilling og deres anvendelse i legemidler

Country Status (18)

Country	Link
US (1)	US6307060B1 (pl)
EP (3)	EP0937041B1 (pl)
JP (1)	JP2001504459A (pl)
CN (1)	CN100391942C (pl)
AT (1)	ATE238280T1 (pl)
AU (1)	AU745331B2 (pl)
CA (1)	CA2271276C (pl)
DE (1)	DE59709927D1 (pl)
DK (2)	DK0937041T3 (pl)
ES (2)	ES2407135T3 (pl)
HU (1)	HU228273B1 (pl)
NO (1)	NO314354B1 (pl)
NZ (1)	NZ336202A (pl)
PL (1)	PL195520B1 (pl)
PT (2)	PT937041E (pl)
RU (1)	RU2238936C2 (pl)
SI (2)	SI0937041T1 (pl)
WO (1)	WO1998021183A1 (pl)

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1997
- 1997-11-11 EP EP97911049A patent/EP0937041B1/de not_active Expired - Lifetime
- 1997-11-11 SI SI9730556T patent/SI0937041T1/xx unknown
- 1997-11-11 NZ NZ336202A patent/NZ336202A/xx not_active IP Right Cessation
- 1997-11-11 EP EP03005232A patent/EP1371645B1/de not_active Expired - Lifetime
- 1997-11-11 WO PCT/AT1997/000245 patent/WO1998021183A1/de not_active Ceased
- 1997-11-11 DE DE59709927T patent/DE59709927D1/de not_active Expired - Lifetime
- 1997-11-11 CA CA002271276A patent/CA2271276C/en not_active Expired - Fee Related
- 1997-11-11 ES ES03005232T patent/ES2407135T3/es not_active Expired - Lifetime
- 1997-11-11 JP JP52194298A patent/JP2001504459A/ja active Pending
- 1997-11-11 DK DK97911049T patent/DK0937041T3/da active
- 1997-11-11 PT PT97911049T patent/PT937041E/pt unknown
- 1997-11-11 PL PL97332595A patent/PL195520B1/pl unknown
- 1997-11-11 EP EP03005233A patent/EP1369414A1/de not_active Withdrawn
- 1997-11-11 RU RU99112115/04A patent/RU2238936C2/ru not_active IP Right Cessation
- 1997-11-11 SI SI9730800T patent/SI1371645T1/sl unknown
- 1997-11-11 AT AT97911049T patent/ATE238280T1/de active
- 1997-11-11 CN CNB971996210A patent/CN100391942C/zh not_active Expired - Fee Related
- 1997-11-11 AU AU48560/97A patent/AU745331B2/en not_active Ceased
- 1997-11-11 DK DK03005232.8T patent/DK1371645T3/da active
- 1997-11-11 HU HU9903791A patent/HU228273B1/hu not_active IP Right Cessation
- 1997-11-11 ES ES97911049T patent/ES2195121T3/es not_active Expired - Lifetime
- 1997-11-11 PT PT3005232T patent/PT1371645E/pt unknown
1999
- 1999-03-03 NO NO19991056A patent/NO314354B1/no not_active IP Right Cessation
- 1999-05-11 US US09/309,960 patent/US6307060B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
SI0937041T1 (en)	2003-10-31
ATE238280T1 (de)	2003-05-15
EP1369414A1 (de)	2003-12-10
ES2195121T3 (es)	2003-12-01
PL195520B1 (pl)	2007-09-28
HUP9903791A2 (hu)	2000-03-28
ES2407135T3 (es)	2013-06-11
US6307060B1 (en)	2001-10-23
CN1237159A (zh)	1999-12-01
SI1371645T1 (sl)	2013-07-31
CN100391942C (zh)	2008-06-04
DK0937041T3 (da)	2003-08-11
DE59709927D1 (de)	2003-05-28
NO991056D0 (no)	1999-03-03
WO1998021183A1 (de)	1998-05-22
CA2271276A1 (en)	1998-05-22
HU228273B1 (en)	2013-02-28
NO991056L (no)	1999-05-11
HUP9903791A3 (en)	2001-10-29
RU2238936C2 (ru)	2004-10-27
HK1061023A1 (en)	2004-09-03
EP1371645B1 (de)	2013-02-20
EP1371645A1 (de)	2003-12-17
PL332595A1 (en)	1999-09-27
NZ336202A (en)	2000-10-27
AU745331B2 (en)	2002-03-21
PT1371645E (pt)	2013-05-21
PT937041E (pt)	2003-09-30
EP0937041A1 (de)	1999-08-25
JP2001504459A (ja)	2001-04-03
EP0937041B1 (de)	2003-04-23
AU4856097A (en)	1998-06-03
CA2271276C (en)	2009-01-13
DK1371645T3 (da)	2013-06-03

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Date	Code	Title	Description
2017-06-26	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
RU2238936C2 (ru)	2004-10-27	Энантиомерно чистые основные эфиры арил-циклоалкилгидроксикарбоновых кислот, способ их получения и применение в лекарственных средствах
US6613795B2 (en)	2003-09-02	Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments
IL174942A (en)	2011-03-31	Derivatives of n-[phenyl(piperidine-2-yl)methyl]arylamides, pharmaceutical compositions comprising them and their use in the preparation of medicaments
US20070299091A1 (en)	2007-12-27	Azaindole Carboxamides
JP6030120B2 (ja)	2016-11-24	Ｃｎｓ障害の治療におけるジベンゾチアゼピン誘導体およびその使用
JPH08505375A (ja)	1996-06-11	置換基をもつトリオール類
US20030166629A1 (en)	2003-09-04	Cyclic quaternary ammonium compounds
NO324869B1 (no)	2007-12-17	Piperidinderivater og legemidler inneholdende disse derivater som den aktive bestanddel
JP2010504311A (ja)	2010-02-12	ピロリジン、インドリジンおよびキノリジンの誘導体、これらの調製およびこれらの治療上の使用
ITMI951930A1 (it)	1997-03-15	Derivati di diarilalchenilammina
WO1995000486A1 (en)	1995-01-05	N-substituted azaheterocyclic carboxylic acids and esters thereof
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