NO314382B1 - Absorbenter for fosfat fra et vandig medium, samt fremgangsmåte ved fremstilling og anvendelse av absorbenten - Google Patents

Absorbenter for fosfat fra et vandig medium, samt fremgangsmåte ved fremstilling og anvendelse av absorbenten Download PDF

Info

Publication number: NO314382B1
Authority: NO; Norway
Prior art keywords: iron; phosphate; suspension; carbohydrates; adsorbent
Prior art date: 1995-12-19

Application number

NO19982722A

Other languages

English (en)

Norwegian (no)

Other versions

NO982722L (no

NO982722D0 (no

Inventor

Peter Geisser

Erik Philipp

Original Assignee

Vifor Internat Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-19

Filing date

1998-06-12

Publication date

2003-03-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7780518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO314382(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-06-12 Application filed by Vifor Internat Ag filed Critical Vifor Internat Ag

1998-06-12 Publication of NO982722D0 publication Critical patent/NO982722D0/no

1998-08-18 Publication of NO982722L publication Critical patent/NO982722L/no

2003-03-17 Publication of NO314382B1 publication Critical patent/NO314382B1/no

Links

229910019142 PO4 Inorganic materials 0.000 title claims description 41
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title claims description 38
239000010452 phosphate Substances 0.000 title claims description 38
238000000034 method Methods 0.000 title claims description 14
239000012736 aqueous medium Substances 0.000 title claims description 8
239000002250 absorbent Substances 0.000 title description 10
230000002745 absorbent Effects 0.000 title description 10
238000002360 preparation method Methods 0.000 title description 7
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 59
239000000725 suspension Substances 0.000 claims description 35
239000003463 adsorbent Substances 0.000 claims description 28
229910052742 iron Inorganic materials 0.000 claims description 26
150000001720 carbohydrates Chemical class 0.000 claims description 21
235000014633 carbohydrates Nutrition 0.000 claims description 21
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
QJZYHAIUNVAGQP-UHFFFAOYSA-N 3-nitrobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid Chemical compound C1C2C=CC1C(C(=O)O)C2(C(O)=O)[N+]([O-])=O QJZYHAIUNVAGQP-UHFFFAOYSA-N 0.000 claims description 16
239000004021 humic acid Substances 0.000 claims description 16
239000000243 solution Substances 0.000 claims description 16
239000007864 aqueous solution Substances 0.000 claims description 14
229910052816 inorganic phosphate Inorganic materials 0.000 claims description 14
-1 chlorine ions Chemical class 0.000 claims description 12
238000001179 sorption measurement Methods 0.000 claims description 11
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 9
229930006000 Sucrose Natural products 0.000 claims description 9
239000005720 sucrose Substances 0.000 claims description 9
159000000007 calcium salts Chemical class 0.000 claims description 8
238000004519 manufacturing process Methods 0.000 claims description 8
239000000460 chlorine Substances 0.000 claims description 6
229910052801 chlorine Inorganic materials 0.000 claims description 6
239000000203 mixture Substances 0.000 claims description 6
239000002244 precipitate Substances 0.000 claims description 6
229920001353 Dextrin Polymers 0.000 claims description 5
239000004375 Dextrin Substances 0.000 claims description 5
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 5
235000019425 dextrin Nutrition 0.000 claims description 5
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 4
239000002585 base Substances 0.000 claims description 4
238000002156 mixing Methods 0.000 claims description 4
150000003839 salts Chemical class 0.000 claims description 4
239000007787 solid Substances 0.000 claims description 4
238000005406 washing Methods 0.000 claims description 4
VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical class [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims description 3
229910052783 alkali metal Inorganic materials 0.000 claims description 3
229910000288 alkali metal carbonate Inorganic materials 0.000 claims description 3
150000008041 alkali metal carbonates Chemical class 0.000 claims description 3
235000014413 iron hydroxide Nutrition 0.000 claims description 3
NCNCGGDMXMBVIA-UHFFFAOYSA-L iron(ii) hydroxide Chemical compound [OH-].[OH-].[Fe+2] NCNCGGDMXMBVIA-UHFFFAOYSA-L 0.000 claims description 3
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 2
229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 2
235000017557 sodium bicarbonate Nutrition 0.000 claims description 2
229910000029 sodium carbonate Inorganic materials 0.000 claims description 2
235000021317 phosphate Nutrition 0.000 description 37
239000000463 material Substances 0.000 description 21
102000006335 Phosphate-Binding Proteins Human genes 0.000 description 10
108010058514 Phosphate-Binding Proteins Proteins 0.000 description 10
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 6
238000010908 decantation Methods 0.000 description 6
239000011574 phosphorus Substances 0.000 description 6
229910052698 phosphorus Inorganic materials 0.000 description 6
239000007788 liquid Substances 0.000 description 5
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 5
229920002472 Starch Polymers 0.000 description 4
VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 description 4
239000001639 calcium acetate Substances 0.000 description 4
235000011092 calcium acetate Nutrition 0.000 description 4
229960005147 calcium acetate Drugs 0.000 description 4
239000012153 distilled water Substances 0.000 description 4
239000000523 sample Substances 0.000 description 4
150000003013 phosphoric acid derivatives Chemical class 0.000 description 3
239000000047 product Substances 0.000 description 3
239000001488 sodium phosphate Substances 0.000 description 3
229910000162 sodium phosphate Inorganic materials 0.000 description 3
235000011008 sodium phosphates Nutrition 0.000 description 3
239000008107 starch Substances 0.000 description 3
235000019698 starch Nutrition 0.000 description 3
235000000346 sugar Nutrition 0.000 description 3
208000020084 Bone disease Diseases 0.000 description 2
229920002307 Dextran Polymers 0.000 description 2
IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 2
238000004458 analytical method Methods 0.000 description 2
239000000969 carrier Substances 0.000 description 2
239000001913 cellulose Substances 0.000 description 2
229920002678 cellulose Polymers 0.000 description 2
239000003153 chemical reaction reagent Substances 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
238000000502 dialysis Methods 0.000 description 2
230000029087 digestion Effects 0.000 description 2
150000004676 glycans Chemical class 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 2
150000007522 mineralic acids Chemical class 0.000 description 2
150000007524 organic acids Chemical class 0.000 description 2
235000005985 organic acids Nutrition 0.000 description 2
AMWVZPDSWLOFKA-UHFFFAOYSA-N phosphanylidynemolybdenum Chemical compound [Mo]#P AMWVZPDSWLOFKA-UHFFFAOYSA-N 0.000 description 2
229920001282 polysaccharide Polymers 0.000 description 2
239000005017 polysaccharide Substances 0.000 description 2
238000001556 precipitation Methods 0.000 description 2
238000003756 stirring Methods 0.000 description 2
229910000406 trisodium phosphate Inorganic materials 0.000 description 2
235000019801 trisodium phosphate Nutrition 0.000 description 2
OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
229920000936 Agarose Polymers 0.000 description 1
GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
229920000945 Amylopectin Polymers 0.000 description 1
235000019890 Amylum Nutrition 0.000 description 1
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
208000037147 Hypercalcaemia Diseases 0.000 description 1
229910021578 Iron(III) chloride Inorganic materials 0.000 description 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
229930195725 Mannitol Natural products 0.000 description 1
208000036696 Microcytic anaemia Diseases 0.000 description 1
IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 1
208000005770 Secondary Hyperparathyroidism Diseases 0.000 description 1
CUPCBVUMRUSXIU-UHFFFAOYSA-N [Fe].OOO Chemical class [Fe].OOO CUPCBVUMRUSXIU-UHFFFAOYSA-N 0.000 description 1
239000000654 additive Substances 0.000 description 1
AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 description 1
150000001398 aluminium Chemical class 0.000 description 1
150000001450 anions Chemical class 0.000 description 1
239000008346 aqueous phase Substances 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
210000001124 body fluid Anatomy 0.000 description 1
239000010839 body fluid Substances 0.000 description 1
230000002308 calcification Effects 0.000 description 1
208000020832 chronic kidney disease Diseases 0.000 description 1
208000022831 chronic renal failure syndrome Diseases 0.000 description 1
210000004913 chyme Anatomy 0.000 description 1
238000010668 complexation reaction Methods 0.000 description 1
239000013068 control sample Substances 0.000 description 1
239000008298 dragée Substances 0.000 description 1
239000003814 drug Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
239000008393 encapsulating agent Substances 0.000 description 1
238000005538 encapsulation Methods 0.000 description 1
230000003181 encephalopathic effect Effects 0.000 description 1
238000001914 filtration Methods 0.000 description 1
235000013305 food Nutrition 0.000 description 1
238000004186 food analysis Methods 0.000 description 1
238000009472 formulation Methods 0.000 description 1
230000002496 gastric effect Effects 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
230000024924 glomerular filtration Effects 0.000 description 1
239000008187 granular material Substances 0.000 description 1
AEIXRCIKZIZYPM-UHFFFAOYSA-M hydroxy(oxo)iron Chemical compound [O][Fe]O AEIXRCIKZIZYPM-UHFFFAOYSA-M 0.000 description 1
230000000148 hypercalcaemia Effects 0.000 description 1
208000030915 hypercalcemia disease Diseases 0.000 description 1
238000009776 industrial production Methods 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
230000002452 interceptive effect Effects 0.000 description 1
150000002505 iron Chemical class 0.000 description 1
UQSXHKLRYXJYBZ-UHFFFAOYSA-N iron oxide Inorganic materials [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 1
235000013980 iron oxide Nutrition 0.000 description 1
RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 1
VBMVTYDPPZVILR-UHFFFAOYSA-N iron(2+);oxygen(2-) Chemical class [O-2].[Fe+2] VBMVTYDPPZVILR-UHFFFAOYSA-N 0.000 description 1
LIKBJVNGSGBSGK-UHFFFAOYSA-N iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[Fe+3].[Fe+3] LIKBJVNGSGBSGK-UHFFFAOYSA-N 0.000 description 1
JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
239000008101 lactose Substances 0.000 description 1
239000000594 mannitol Substances 0.000 description 1
235000010355 mannitol Nutrition 0.000 description 1
239000002609 medium Substances 0.000 description 1
229910044991 metal oxide Inorganic materials 0.000 description 1
239000004570 mortar (masonry) Substances 0.000 description 1
239000008188 pellet Substances 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
239000012071 phase Substances 0.000 description 1
235000002949 phytic acid Nutrition 0.000 description 1
229940068041 phytic acid Drugs 0.000 description 1
239000000467 phytic acid Substances 0.000 description 1
239000000843 powder Substances 0.000 description 1
238000011321 prophylaxis Methods 0.000 description 1
210000002966 serum Anatomy 0.000 description 1
AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
AVPCPPOOQICIRJ-UHFFFAOYSA-L sodium glycerol 2-phosphate Chemical compound [Na+].[Na+].OCC(CO)OP([O-])([O-])=O AVPCPPOOQICIRJ-UHFFFAOYSA-L 0.000 description 1
230000006641 stabilisation Effects 0.000 description 1
238000011105 stabilization Methods 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000003860 storage Methods 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
208000011580 syndromic disease Diseases 0.000 description 1
239000003826 tablet Substances 0.000 description 1
238000011282 treatment Methods 0.000 description 1
210000001835 viscera Anatomy 0.000 description 1
229910000859 α-Fe Inorganic materials 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
- A23L5/27—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption
- A23L5/273—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption using adsorption or absorption agents, resins, synthetic polymers, or ion exchangers
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/015—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
- B01J20/06—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group B01J20/04

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Polymers & Plastics (AREA)
Food Science & Technology (AREA)
Engineering & Computer Science (AREA)
Inorganic Chemistry (AREA)
Health & Medical Sciences (AREA)
Zoology (AREA)
Animal Husbandry (AREA)
Nutrition Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Analytical Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Water Treatment By Sorption (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO19982722A 1995-12-19 1998-06-12 Absorbenter for fosfat fra et vandig medium, samt fremgangsmåte ved fremstilling og anvendelse av absorbenten NO314382B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19547356A DE19547356A1 (de)	1995-12-19	1995-12-19	Adsorbens für Phosphat aus wäßrigem Medium, dessen Herstellung und Verwendung
PCT/EP1996/005695 WO1997022266A1 (de)	1995-12-19	1996-12-19	Adsorbens für phosphat aus wässrigem medium, dessen herstellung und verwendung

Publications (3)

Publication Number	Publication Date
NO982722D0 NO982722D0 (no)	1998-06-12
NO982722L NO982722L (no)	1998-08-18
NO314382B1 true NO314382B1 (no)	2003-03-17

Family

ID=7780518

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO19982722A NO314382B1 (no)	1995-12-19	1998-06-12	Absorbenter for fosfat fra et vandig medium, samt fremgangsmåte ved fremstilling og anvendelse av absorbenten
NO2015004C NO2015004I1 (no)	1995-12-19	2015-02-17	Blanding av polynukleært jern(III)oksyhydroksid, sukrose og stivelser

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO2015004C NO2015004I1 (no)	1995-12-19	2015-02-17	Blanding av polynukleært jern(III)oksyhydroksid, sukrose og stivelser

Country Status (23)

Country	Link
US (1)	US6174442B1 (2)
EP (1)	EP0868125B1 (2)
JP (1)	JP3665345B2 (2)
KR (1)	KR100390481B1 (2)
AR (1)	AR005026A1 (2)
AT (1)	ATE207707T1 (2)
AU (1)	AU1374797A (2)
BR (2)	BRPI9612138B8 (2)
CA (1)	CA2240668C (2)
DE (2)	DE19547356A1 (2)
DK (1)	DK0868125T3 (2)
ES (1)	ES2171758T3 (2)
FR (1)	FR15C0018I2 (2)
IN (1)	IN190206B (2)
LT (1)	LTC0868125I2 (2)
LU (1)	LU92626I2 (2)
NO (2)	NO314382B1 (2)
PT (1)	PT868125E (2)
SI (1)	SI0868125T1 (2)
TR (1)	TR199801152T2 (2)
TW (1)	TW457090B (2)
WO (1)	WO1997022266A1 (2)
ZA (1)	ZA9610643B (2)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9720061D0 (en) *	1997-09-19	1997-11-19	Crosfield Joseph & Sons	Metal compounds as phosphate binders
DE19853529A1 (de) *	1998-11-20	2000-05-25	Dieter A Hiller	Regenwasserabfluß-Schadstofffilter
DE20109443U1 (de)	2001-05-30	2001-08-09	ATEC Dr. Mann GmbH, 74847 Obrigheim	Vorrichtung zur Dekontamination von Wässern, die Spuren von Arsen, Mangan und Eisen beinhalten
EP1457256A1 (en) *	2001-12-21	2004-09-15	Muromachi Chemical Co., Ltd	Adsorbent for phosphoric acid
AU2004279320A1 (en) *	2003-09-23	2005-04-21	Ortho Therapeutics, Llc.	Bioabsorbable putty-like hemostatic implants
US7955616B2 (en)	2003-09-23	2011-06-07	Orthocon, Inc.	Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
NZ545521A (en) *	2003-09-23	2010-02-26	Orthocon Inc	Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
DE102004031181A1 (de) *	2004-06-28	2006-01-19	Vifor (International) Ag	Phosphatadsorbens
US8603528B2 (en) *	2004-09-16	2013-12-10	Abyrx, Inc.	Compositions and method for the reduction of post-operative pain
US20060169014A1 (en) *	2005-01-31	2006-08-03	Laboratorios Diet-Esthetic, S.A.	Composition for the nutrition and irrigation of plants
WO2006134828A1 (ja) *	2005-06-09	2006-12-21	Tomotaka Yanagita	アニオン吸着剤、水質又は土壌浄化剤及びそれらの製造方法
GB2430793A (en) *	2005-09-29	2007-04-04	Bookham Technology Plc	Bragg grating reflection strength control
MY157620A (en)	2006-01-31	2016-06-30	Cytochroma Dev Inc	A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
ITRM20060204A1 (it) *	2006-04-10	2007-10-11	Vincenzo Savica	Farmaci e alimentei per diete normoproteiche iperproteiche ipopro teiche tutte ipofosforiche e bevande ipofosforiche
WO2008001443A1 (fr) *	2006-06-29	2008-01-03	J-Pharma Co., Ltd.	Agent thérapeutique préventif pour déficience en phosphore, agent oral pour adsorption d'ions de phosphate contenus dans un aliment, une boisson et une substance chimique et leur procédé de préparation
DE102006055757B4 (de)	2006-11-25	2012-03-15	Continental Teves Ag & Co. Ohg	Selbstpumpende Niveauregulierung
PT2319804E (pt) *	2006-12-14	2014-11-24	Novartis Ag	Adsorvente de fosfato à base de ferro (iii)-carboidrato
DK2319804T3 (en)	2006-12-14	2015-01-19	Novartis Ag	Iron (III) -carbohydrat-based phosphatadsorbens
EP1932807A1 (en) *	2006-12-14	2008-06-18	Novartis AG	Inorganic compounds
US7927493B2 (en) *	2007-05-11	2011-04-19	Ch2M Hill, Inc.	Low phosphorus water treatment methods
GB0714670D0 (en)	2007-07-27	2007-09-05	Ineos Healthcare Ltd	Use
GB0720220D0 (en)	2007-10-16	2007-11-28	Ineos Healthcare Ltd	Compound
TWI592159B (zh)	2007-11-16	2017-07-21	威佛（國際）股份有限公司	藥學組成物
US9101716B2 (en)	2008-02-01	2015-08-11	Baxter International Inc.	Multi-pass dialysis
KR20110018434A (ko) *	2008-06-13	2011-02-23	노파르티스 아게	철 함유 인산염 흡착제의 제조를 위한 제조 방법
GB0814326D0 (en) *	2008-08-05	2008-09-10	Medical Res Council	Phosphate binding materials and their uses
AR076070A1 (es) *	2009-03-02	2011-05-18	Vifor Int Ag	Absorbente de fosfato para el tratamiento de la hiperfosfatemia
CN108938585A (zh)	2009-07-21	2018-12-07	凯克斯生物制药公司	柠檬酸铁剂型
GB0913525D0 (en)	2009-08-03	2009-09-16	Ineos Healthcare Ltd	Method
US8721887B2 (en)	2009-12-07	2014-05-13	Ch2M Hill, Inc.	Method and system for treating wastewater
GB201001779D0 (en)	2010-02-04	2010-03-24	Ineos Healthcare Ltd	Composition
EP2548562A1 (de) *	2011-07-18	2013-01-23	SeBo GmbH	Kombinationstherapie mit Eisen-basierenden Phosphatadsorbern
WO2013056085A1 (en) *	2011-10-13	2013-04-18	Vidasym, Inc.	Iron-fiber composition, preparation and uses thereof
RU2496722C1 (ru) *	2012-04-10	2013-10-27	Леонид Асхатович Мазитов	Способ очистки сточной воды от фосфатов
US9796792B2 (en)	2013-03-08	2017-10-24	Vidasym, Inc.	Metal ion-functional fiber component complex compositions, preparation and uses thereof
PT3073997T (pt)	2013-11-27	2020-09-08	Vifor Int Ag	Composição farmacêutica, compreendendo partículas de ligante de fosfato
WO2015181205A1 (en)	2014-05-28	2015-12-03	Biaqua B.V.	Method for removing phosphate from water fractions
EP3157516A4 (en)	2014-06-22	2017-12-13	Dexcel Pharma Technologies Ltd.	Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
US20170259241A1 (en)	2014-09-10	2017-09-14	Lupin Limited	A manufacturing process for an iron containing adsorbent
DE102014019388A1 (de)	2014-12-29	2016-06-30	Susanne Wagner	Arzneimittel auf der Basis von Maghämit zur gleichzeitigen Reduzierung der gastrointestinalen Natriumresorption und Phosphatresorption
KR101609802B1 (ko)	2015-02-09	2016-04-06	광주과학기술원	아카가나이트 분말이 고정화된 수중 산소산 음이온 제거 및 회수용 입상 흡착제 및 그 제조방법
WO2017061118A1 (ja) *	2015-10-09	2017-04-13	高橋金属株式会社	陰イオン吸着方法
EP3829761A1 (en)	2018-07-30	2021-06-09	Interquim S.A.	Process for preparing an adsorbent for phosphate in aqueous medium
US12331066B2 (en)	2019-02-12	2025-06-17	Biophore India Pharmaceuticals Pvt. Ltd	Process for the preparation of sucroferric oxyhydroxide
CN119488480A (zh)	2019-02-28	2025-02-21	雷尼布斯治疗公司	新型铁组合物及其制造和使用方法
WO2020181256A1 (en)	2019-03-06	2020-09-10	Renibus Therapeutics, Inc.	Novel tetrahydrocurcumin compositions, methods of making, and methods of using the same
US12329778B2 (en)	2020-01-16	2025-06-17	Vifor Fresenius Medical Care Renal Pharma Ltd	Particles of a mixture of iron(III)-oxyhydroxide, sucrose and one or more starches, preferably of sucroferric oxyhydroxide
EP3932535A1 (en)	2020-07-01	2022-01-05	Vifor Fresenius Medical Care Renal Pharma, Ltd.	Manufacturing method for polynuclear iron compounds stabilized by carbohydrates and/or humic acid

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7703937A (nl)	1977-04-12	1978-10-16	Organon Teknika Bv	Inrichting voorzien van een sorbent voor het zuiveren van bloed; een voor orale toepassing geschikt sorbent en een werkwijze voor vervaar- diging van het sorbent.
US4581141A (en) *	1978-02-27	1986-04-08	Purdue Research Foundation	Dialysis material and method for removing uremic substances
DE3042764A1 (de)	1980-11-13	1982-06-09	Rheinische Braunkohlenwerke AG, 5000 Köln	Verfahren zur herstellung von polyfunktionellen ionenaustauschern
US4530963A (en) *	1982-08-20	1985-07-23	Devoe-Holbein International, N.V.	Insoluble chelating compositions
AT382326B (de)	1983-10-25	1987-02-10	Johann Merka	Verfahren zur herstellung von sorptionsmitteln auf basis von humaten, insbesondere zu filtrierzwecken
DE3422249A1 (de)	1984-06-15	1985-12-19	Pfeifer & Langen, 5000 Köln	Wasserloesliches eisendextran und verfahren zu seiner herstellung
US4970079A (en) *	1989-06-05	1990-11-13	Purdue Research Foundation	Method and composition of oxy-iron compounds for treatment of hyperphosphatemia
US5411569A (en) *	1991-08-28	1995-05-02	Kemiron, Inc.	Iron humate product
DE4239442C2 (de) *	1992-11-24	2001-09-13	Sebo Gmbh	Verwendung eines mit polynuklearen Metalloxidhydroxiden modifizierten Adsorptionsmaterials zur selektiven Elimination von anorganischem Phosphat aus proteinhaltigen Flüssigkeiten
CO4410161A1 (es)	1994-02-28	1997-01-09	Kellog Co	Producto de cereal listo para comer fortificado con complejo de edta ferrico y metodo para producirlo

1995
- 1995-12-19 DE DE19547356A patent/DE19547356A1/de not_active Withdrawn
1996
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- 1996-12-19 PT PT96944004T patent/PT868125E/pt unknown
- 1996-12-19 US US09/077,944 patent/US6174442B1/en not_active Expired - Lifetime
- 1996-12-19 KR KR10-1998-0704632A patent/KR100390481B1/ko not_active Expired - Lifetime
- 1996-12-19 AT AT96944004T patent/ATE207707T1/de active
- 1996-12-19 WO PCT/EP1996/005695 patent/WO1997022266A1/de not_active Ceased
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1998
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2014
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- 2015-02-17 NO NO2015004C patent/NO2015004I1/no not_active IP Right Cessation
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ZA9610643B (en)	1997-06-24
AR005026A1 (es)	1999-04-07
NO2015004I2 (2)	2015-02-17
BR9612138A (pt)	1999-07-13
LTC0868125I2 (lt)	2016-12-12
KR20000064462A (ko)	2000-11-06
TR199801152T2 (xx)	1998-09-21
JP2000506372A (ja)	2000-05-30
ES2171758T3 (es)	2002-09-16
US6174442B1 (en)	2001-01-16
WO1997022266A1 (de)	1997-06-26
DE59608089D1 (de)	2001-12-06
NO982722L (no)	1998-08-18
EP0868125A1 (de)	1998-10-07
BRPI9612138B1 (2)	2009-09-22
BR9612138B1 (pt)	2009-08-11
IN190206B (2)	2003-06-28
DK0868125T3 (da)	2001-11-19
LU92626I2 (fr)	2015-10-21
NO2015004I1 (no)	2015-03-02
JP3665345B2 (ja)	2005-06-29
AU1374797A (en)	1997-07-14
SI0868125T1 (en)	2002-10-31
PT868125E (pt)	2002-04-29
KR100390481B1 (ko)	2003-09-26
EP0868125B1 (de)	2001-10-31
TW457090B (en)	2001-10-01
FR15C0018I2 (fr)	2015-07-24
CA2240668A1 (en)	1997-06-26
DE19547356A1 (de)	1997-06-26
NO982722D0 (no)	1998-06-12
BRPI9612138B8 (pt)	2018-04-17
ATE207707T1 (de)	2001-11-15
FR15C0018I1 (2)	2015-04-03
CA2240668C (en)	2006-07-04

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Publication	Publication Date	Title
NO314382B1 (no)	2003-03-17	Absorbenter for fosfat fra et vandig medium, samt fremgangsmåte ved fremstilling og anvendelse av absorbenten
Meyer et al.	1982	Lattice defects in nonstoichiometric calcium hydroxylapatites. A chemical approach
US20140335202A1 (en)	2014-11-13	Iron Sulfate-Based Phosphate Adsorbent
Chinachoti et al.	1984	Interaction of sucrose with starch during dehydration as shown by water sorption
Ohno et al.	1997	Inhibitory effects of crop residue‐derived organic ligands on phosphate adsorption kinetics
JP2008516971A (ja)	2008-05-22	錠剤による負荷が軽減されるリン酸塩結合剤
CN109046267A (zh)	2018-12-21	一种柠檬酸接枝壳聚糖小球的制备方法及其应用
CA1333884C (en)	1995-01-10	Phosphorous binder
Kennedy et al.	1976	Hydrous titanium oxides–new supports for the simple immobilisation of enzymes
Pankratov et al.	2017	Sorption of humic substances on a weakly basic anion-exchange resin: Relationship with the adsorbate structure
Nordbö	1972	The affinity of chlorhexidine for hydroxyapatite and tooth surfaces
US4664916A (en)	1987-05-12	Method for the preparation of a food having desalinating activity
Shimizu et al.	1983	A newly prepared surface‐treated oxystarch for removal of urea
US3012937A (en)	1961-12-12	Iron resin salt and method of making
Yamaguchi et al.	1999	Oral phosphate binders: Phosphate binding capacity of iron (III) hydroxide complexes containing saccharides; and their effect on the urinary excretion of calcium and phosphate in rats
EP1845777A2 (en)	2007-10-24	Starch derivatives and other derivatives, production processes therefor, and wound healing applications therefor
JPH062580B2 (ja)	1994-01-12	ベーマイト状水酸化アルミニウム、その製造法及びそれを有効成分とする経口用リン酸イオン吸着剤
Jing et al.	1992	Removal of Phosphate from Dilute Phosphate Solution by an Iron Chitosan Complex to Be Used as an Oral Sorbent.
Rankin et al.	2001	The development and in-vitro evaluation of novel mixed metal hydroxy-carbonate compounds as phosphate binders
KR20000022338A (ko)	2000-04-25	네마시스티스 데시피엔스 열수 추출물 및 이의 용도
WO2019159914A1 (ja)	2019-08-22	カルシウム溶解促進剤
Blezek et al.	1970	Some dissolution aspects of ferrous sulfate tablets
JPH0513092B2 (2)	1993-02-19
JPS6257381B2 (2)	1987-12-01
US2968653A (en)	1961-01-17	Process for preparing a water-soluble cobalt salt and soluble starch