NO318080B1 - 4,4- og 3,3-disubstiterte piperidin-forbindelser med veksthormonfrigjorende egenskaper,farmasoytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene eller preparatene til fremstilling av medikamenter - Google Patents

4,4- og 3,3-disubstiterte piperidin-forbindelser med veksthormonfrigjorende egenskaper,farmasoytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene eller preparatene til fremstilling av medikamenter Download PDF

Info

Publication number: NO318080B1
Authority: NO; Norway
Prior art keywords: amino; benzyl; propionyl; carboxylic acid; piperidin
Prior art date: 1998-05-11

Application number

NO20005668A

Other languages

English (en)

Norwegian (no)

Other versions

NO20005668D0 (no

NO20005668L (no

Inventor

Thomas Kruse Hansen

Michael Ankersen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-11

Filing date

2000-11-10

Publication date

2005-01-31

2000-11-10 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

2000-11-10 Publication of NO20005668D0 publication Critical patent/NO20005668D0/no

2001-01-10 Publication of NO20005668L publication Critical patent/NO20005668L/no

2005-01-31 Publication of NO318080B1 publication Critical patent/NO318080B1/no

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Peptides Or Proteins (AREA)

NO20005668A 1998-05-11 2000-11-10 4,4- og 3,3-disubstiterte piperidin-forbindelser med veksthormonfrigjorende egenskaper,farmasoytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene eller preparatene til fremstilling av medikamenter NO318080B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DK63698		1998-05-11
DKPA199800875		1998-07-01
PCT/DK1999/000260 WO1999058501A1 (en)	1998-05-11	1999-05-10	Compounds with growth hormone releasing properties

Publications (3)

Publication Number	Publication Date
NO20005668D0 NO20005668D0 (no)	2000-11-10
NO20005668L NO20005668L (no)	2001-01-10
NO318080B1 true NO318080B1 (no)	2005-01-31

Family

ID=26064372

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20005668A NO318080B1 (no)	1998-05-11	2000-11-10	4,4- og 3,3-disubstiterte piperidin-forbindelser med veksthormonfrigjorende egenskaper,farmasoytiske preparater som omfatter forbindelsene, samt anvendelse av forbindelsene eller preparatene til fremstilling av medikamenter

Country Status (23)

Country	Link
EP (1)	EP1077941B1 (de)
JP (2)	JP4142253B2 (de)
KR (1)	KR100593601B1 (de)
CN (1)	CN1142911C (de)
AT (1)	ATE439346T1 (de)
AU (1)	AU757217B2 (de)
BR (1)	BR9910329A (de)
CA (1)	CA2329881C (de)
CY (1)	CY1109626T1 (de)
CZ (1)	CZ301276B6 (de)
DE (1)	DE69941255D1 (de)
DK (1)	DK1077941T3 (de)
ES (1)	ES2331102T3 (de)
HU (1)	HUP0102071A3 (de)
IL (2)	IL139090A0 (de)
NO (1)	NO318080B1 (de)
PL (1)	PL194560B1 (de)
PT (1)	PT1077941E (de)
RU (1)	RU2243215C2 (de)
SI (1)	SI1077941T1 (de)
TW (1)	TWI222969B (de)
UA (1)	UA72210C2 (de)
WO (1)	WO1999058501A1 (de)

Families Citing this family (22)

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Publication number	Priority date	Publication date	Assignee	Title
DE60021521T4 (de)	1999-09-29	2006-09-21	Ortho-Mcneil Pharmaceutical, Inc.	Isonipecotamide zur behandlung von integrin vermittelten störungen
UA73530C2 (uk) *	1999-11-10	2005-08-15	Ново Нордіск А/С	Сполука з властивостями вивільнювати гормон росту
US20010020012A1 (en) *	2000-02-01	2001-09-06	Andersen Maibritt Bansholm	Use of compounds for the regulation of food intake
AU2002230665A1 (en)	2000-12-06	2002-06-18	Sepracor, Inc.	4,4-disubstituted piperidines for use as dopamine, serotonin and norepinephrine ligands
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1999
- 1999-05-10 DK DK99919125T patent/DK1077941T3/da active
- 1999-05-10 IL IL13909099A patent/IL139090A0/xx active IP Right Grant
- 1999-05-10 CN CNB998060100A patent/CN1142911C/zh not_active Expired - Lifetime
- 1999-05-10 HU HU0102071A patent/HUP0102071A3/hu unknown
- 1999-05-10 ES ES99919125T patent/ES2331102T3/es not_active Expired - Lifetime
- 1999-05-10 SI SI9931036T patent/SI1077941T1/sl unknown
- 1999-05-10 AU AU37010/99A patent/AU757217B2/en not_active Expired
- 1999-05-10 AT AT99919125T patent/ATE439346T1/de active
- 1999-05-10 PT PT99919125T patent/PT1077941E/pt unknown
- 1999-05-10 DE DE69941255T patent/DE69941255D1/de not_active Expired - Lifetime
- 1999-05-10 EP EP99919125A patent/EP1077941B1/de not_active Expired - Lifetime
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- 1999-05-10 WO PCT/DK1999/000260 patent/WO1999058501A1/en not_active Ceased
- 1999-05-10 RU RU2000131184/04A patent/RU2243215C2/ru active
- 1999-05-10 BR BR9910329-0A patent/BR9910329A/pt not_active Application Discontinuation
- 1999-05-10 KR KR1020007012458A patent/KR100593601B1/ko not_active Expired - Lifetime
- 1999-05-10 JP JP2000548305A patent/JP4142253B2/ja not_active Expired - Lifetime
- 1999-05-10 CZ CZ20004129A patent/CZ301276B6/cs not_active IP Right Cessation
- 1999-05-10 PL PL344042A patent/PL194560B1/pl unknown
- 1999-05-24 TW TW088108436A patent/TWI222969B/zh not_active IP Right Cessation
- 1999-10-05 UA UA2000116293A patent/UA72210C2/uk unknown
2000
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Publication number	Publication date
KR100593601B1 (ko)	2006-06-28
CN1300281A (zh)	2001-06-20
PL194560B1 (pl)	2007-06-29
NO20005668D0 (no)	2000-11-10
AU757217B2 (en)	2003-02-06
ES2331102T3 (es)	2009-12-21
EP1077941B1 (de)	2009-08-12
CY1109626T1 (el)	2014-08-13
RU2243215C2 (ru)	2004-12-27
UA72210C2 (uk)	2005-02-15
DK1077941T3 (da)	2009-12-07
TWI222969B (en)	2004-11-01
SI1077941T1 (sl)	2010-01-29
BR9910329A (pt)	2001-01-30
JP2004500312A (ja)	2004-01-08
CN1142911C (zh)	2004-03-24
JP2008156372A (ja)	2008-07-10
CA2329881C (en)	2010-03-16
JP4142253B2 (ja)	2008-09-03
AU3701099A (en)	1999-11-29
KR20010043422A (ko)	2001-05-25
IL139090A0 (en)	2001-11-25
ATE439346T1 (de)	2009-08-15
HUP0102071A3 (en)	2002-06-28
JP4938708B2 (ja)	2012-05-23
PL344042A1 (en)	2001-09-24
CZ20004129A3 (en)	2001-06-13
WO1999058501A1 (en)	1999-11-18
DE69941255D1 (de)	2009-09-24
IL139090A (en)	2007-03-08
NO20005668L (no)	2001-01-10
EP1077941A1 (de)	2001-02-28
PT1077941E (pt)	2010-07-01
CA2329881A1 (en)	1999-11-18
CZ301276B6 (cs)	2009-12-30
HUP0102071A2 (hu)	2002-03-28

Legal Events

Date	Code	Title	Description
2013-07-08	CHAD	Change of the owner's name or address (par. 44 patent law, par. patentforskriften)	Owner name: HELSINN HEALTHCARE SA, CH
2019-06-11	MK1K	Patent expired

Publication	Publication Date	Title
JP4938708B2 (ja)	2012-05-23	成長ホルモン放出特性を有する化合物
US6303620B1 (en)	2001-10-16	Compounds with growth hormone releasing properties
US6576648B2 (en)	2003-06-10	Compound with growth hormone releasing properties
NO312242B1 (no)	2002-04-15	Forbindelser med veksthormonfrigjörende egenskaper, farmasöytiske preparater som omfatter dissse, samt anvendelse avforbindelsene til fremstilling av medikamenter
CA2334315C (en)	2011-07-26	Compounds with growth hormone releasing properties
US7576062B2 (en)	2009-08-18	Compounds with growth hormone releasing properties
MXPA00010585A (en)	2001-07-31	Compounds with growth hormone releasing properties
MXPA00012489A (en)	2002-07-25	Compounds with growth hormone releasing properties
IL149049A (en)	2007-07-24	2 - amino - n - [(1r) - 2 - [(3r) - 3 benzyl - 3 - (benzyl - 3 - (n', n', n - trimethylhydrazinocarbonyl) piperidin - 1 - yl] - 1 - (1h - indol - 3 - ylmethyl) - 2 oxoethyl] - 2 - methylpropionamide, pharmaceutical composition comprising it and its use for the manufacturing of medicaments for releasing growth hormone