NO326848B1 - Fremgangsmate for fremstilling av desglukodesrhamno-ruscin ved hydrolyse av Ruscus aculeatus steroidglykosider med Aspergillus niger - Google Patents

Fremgangsmate for fremstilling av desglukodesrhamno-ruscin ved hydrolyse av Ruscus aculeatus steroidglykosider med Aspergillus niger Download PDF

Info

Publication number: NO326848B1
Authority: NO; Norway
Prior art keywords: hydrolysis; aspergillus niger; fermentation; glycosides; nutrient broth
Prior art date: 1999-06-01

Application number

NO20015824A

Other languages

English (en)

Norwegian (no)

Other versions

NO20015824L (no

NO20015824D0 (no

Inventor

Walter Acquati

Cesare Ponzone

Original Assignee

Indena Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-01

Filing date

2001-11-29

Publication date

2009-02-02

2001-11-29 Application filed by Indena Spa filed Critical Indena Spa

2001-11-29 Publication of NO20015824L publication Critical patent/NO20015824L/no

2001-11-29 Publication of NO20015824D0 publication Critical patent/NO20015824D0/no

2009-02-02 Publication of NO326848B1 publication Critical patent/NO326848B1/no

Links

238000000034 method Methods 0.000 title claims abstract description 19
241000228245 Aspergillus niger Species 0.000 title claims abstract description 8
230000007062 hydrolysis Effects 0.000 title claims abstract description 7
238000006460 hydrolysis reaction Methods 0.000 title claims abstract description 7
229930002534 steroid glycoside Natural products 0.000 title claims abstract description 7
240000000353 Ruscus aculeatus Species 0.000 title claims abstract description 6
235000003500 Ruscus aculeatus Nutrition 0.000 title claims abstract description 6
238000002360 preparation method Methods 0.000 title abstract description 3
238000000855 fermentation Methods 0.000 claims abstract description 17
230000004151 fermentation Effects 0.000 claims abstract description 17
239000000758 substrate Substances 0.000 claims abstract description 8
241000233866 Fungi Species 0.000 claims abstract description 4
229930182470 glycoside Natural products 0.000 claims abstract description 4
150000002338 glycosides Chemical class 0.000 claims abstract description 4
235000015097 nutrients Nutrition 0.000 claims description 15
PKQGPNNFRIIDFC-MTRMYNQZSA-N Ruscoside Chemical compound O([C@@H]1[C@@H](O)[C@H](C)O[C@H]([C@@H]1O)O[C@@H]1[C@@H](O)[C@@H](O)CO[C@H]1O[C@@H]1CC2=CC[C@H]3[C@@H]4C[C@H]5[C@@H]([C@]4(CC[C@@H]3[C@@]2(C)[C@H](O)C1)C)[C@@H]([C@@](O5)(O)CCC(=C)CO[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O PKQGPNNFRIIDFC-MTRMYNQZSA-N 0.000 claims description 11
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238000004519 manufacturing process Methods 0.000 claims description 7
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 5
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SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 claims description 2
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AIUDWMLXCFRVDR-UHFFFAOYSA-N dimethyl 2-(3-ethyl-3-methylpentyl)propanedioate Chemical class CCC(C)(CC)CCC(C(=O)OC)C(=O)OC AIUDWMLXCFRVDR-UHFFFAOYSA-N 0.000 description 1
230000000694 effects Effects 0.000 description 1
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239000011777 magnesium Chemical class 0.000 description 1
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239000011591 potassium Substances 0.000 description 1
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GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides

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Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Steroid Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

NO20015824A 1999-06-01 2001-11-29 Fremgangsmate for fremstilling av desglukodesrhamno-ruscin ved hydrolyse av Ruscus aculeatus steroidglykosider med Aspergillus niger NO326848B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1999MI001223A ITMI991223A1 (it)	1999-06-01	1999-06-01	Processo per la preparazione di derivati di glicosidi steroidei di ruscus aculeatus
PCT/EP2000/004794 WO2000073489A1 (en)	1999-06-01	2000-05-26	A process for the preparation of derivatives of ruscus aculeatus steroid glycosides

Publications (3)

Publication Number	Publication Date
NO20015824L NO20015824L (no)	2001-11-29
NO20015824D0 NO20015824D0 (no)	2001-11-29
NO326848B1 true NO326848B1 (no)	2009-02-02

Family

ID=11383097

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20015824A NO326848B1 (no)	1999-06-01	2001-11-29	Fremgangsmate for fremstilling av desglukodesrhamno-ruscin ved hydrolyse av Ruscus aculeatus steroidglykosider med Aspergillus niger

Country Status (21)

Country	Link
US (1)	US6528280B1 (de)
EP (1)	EP1181384B1 (de)
JP (1)	JP4699661B2 (de)
KR (1)	KR100670413B1 (de)
CN (1)	CN1261587C (de)
AT (1)	ATE290603T1 (de)
AU (1)	AU773234B2 (de)
CA (1)	CA2375087C (de)
CZ (1)	CZ301224B6 (de)
DE (1)	DE60018560T2 (de)
ES (1)	ES2237436T3 (de)
HK (1)	HK1046432B (de)
HU (1)	HUP0201380A3 (de)
IL (1)	IL146827A0 (de)
IT (1)	ITMI991223A1 (de)
NO (1)	NO326848B1 (de)
PL (1)	PL200908B1 (de)
PT (1)	PT1181384E (de)
RU (1)	RU2249043C2 (de)
SK (1)	SK286195B6 (de)
WO (1)	WO2000073489A1 (de)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009138994A1 (en) *	2008-05-14	2009-11-19	Biocon Limited	A fermentation process for the production of secondary metabolites
CN102504007B (zh) *	2011-12-15	2013-09-25	成都普思生物科技有限公司	一种鲁斯考皂苷元单体的分离纯化方法
CN103588852B (zh) *	2013-11-26	2016-03-30	陕西嘉禾生物科技股份有限公司	从假叶树中提取分离鲁斯可皂苷元的方法

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1999
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2000
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Also Published As

Publication number	Publication date
PT1181384E (pt)	2005-06-30
KR100670413B1 (ko)	2007-01-17
EP1181384A1 (de)	2002-02-27
ATE290603T1 (de)	2005-03-15
CA2375087C (en)	2011-05-03
HK1046432A1 (en)	2003-01-10
KR20020011428A (ko)	2002-02-08
CN1353767A (zh)	2002-06-12
IL146827A0 (en)	2002-07-25
SK286195B6 (sk)	2008-05-06
PL352016A1 (en)	2003-07-14
PL200908B1 (pl)	2009-02-27
DE60018560D1 (de)	2005-04-14
RU2249043C2 (ru)	2005-03-27
HUP0201380A2 (en)	2002-08-28
CA2375087A1 (en)	2000-12-07
DE60018560T2 (de)	2005-08-18
CN1261587C (zh)	2006-06-28
NO20015824L (no)	2001-11-29
US6528280B1 (en)	2003-03-04
CZ301224B6 (cs)	2009-12-16
EP1181384B1 (de)	2005-03-09
HK1046432B (zh)	2007-01-12
NO20015824D0 (no)	2001-11-29
AU5809900A (en)	2000-12-18
ITMI991223A1 (it)	2000-12-01
WO2000073489A1 (en)	2000-12-07
JP4699661B2 (ja)	2011-06-15
HUP0201380A3 (en)	2007-10-29
ITMI991223A0 (it)	1999-06-01
JP2003501045A (ja)	2003-01-14
CZ20014283A3 (cs)	2002-04-17
ES2237436T3 (es)	2005-08-01
AU773234B2 (en)	2004-05-20
SK17452001A3 (sk)	2002-04-04

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