NO327937B1 - R-(-)-1-[2-(7-klorbenzo[b]tiofen-3-yl-metoksy)-2-(2,4-diklorfenyl)-etyl]-1H-imidazol, fremgangsmate for fremstilling derav, preparat derav, samt anvendelse derav for behandling av soppinfeksjoner hos mennesker eller dyr, og bekjempelse av avlingssykdommer - Google Patents

R-(-)-1-[2-(7-klorbenzo[b]tiofen-3-yl-metoksy)-2-(2,4-diklorfenyl)-etyl]-1H-imidazol, fremgangsmate for fremstilling derav, preparat derav, samt anvendelse derav for behandling av soppinfeksjoner hos mennesker eller dyr, og bekjempelse av avlingssykdommer Download PDF

Info

Publication number
NO327937B1
NO327937B1 NO20043377A NO20043377A NO327937B1 NO 327937 B1 NO327937 B1 NO 327937B1 NO 20043377 A NO20043377 A NO 20043377A NO 20043377 A NO20043377 A NO 20043377A NO 327937 B1 NO327937 B1 NO 327937B1
Authority
NO
Norway
Prior art keywords
dichlorophenyl
chlorobenzo
thiophen
methoxy
ethyl
Prior art date
Application number
NO20043377A
Other languages
English (en)
Norwegian (no)
Other versions
NO20043377L (no
Inventor
Rafael Foguet
Jorge Ramentol
Antonio Guglietta
Celia Palacin
Luis Anglada
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of NO20043377L publication Critical patent/NO20043377L/no
Publication of NO327937B1 publication Critical patent/NO327937B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO20043377A 2002-02-11 2004-08-13 R-(-)-1-[2-(7-klorbenzo[b]tiofen-3-yl-metoksy)-2-(2,4-diklorfenyl)-etyl]-1H-imidazol, fremgangsmate for fremstilling derav, preparat derav, samt anvendelse derav for behandling av soppinfeksjoner hos mennesker eller dyr, og bekjempelse av avlingssykdommer NO327937B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200200328A ES2203316B1 (es) 2002-02-11 2002-02-11 R-(-)-1-(2-(7-cloro-benzo(b)tiofen-3-il-metoxi)-2-(2,4-dicloro-fenil)-etil)1h-imidazol.
PCT/EP2003/001089 WO2003068770A1 (en) 2002-02-11 2003-02-04 R- (-) -1- [2- (7-CHLOROBENZO [b] THIOPHEN-3 -YL- METHOXY) -2- (2,4-DICHLOROPHENYL) -ETHYL] -1H-IMIDAZOLE

Publications (2)

Publication Number Publication Date
NO20043377L NO20043377L (no) 2004-08-13
NO327937B1 true NO327937B1 (no) 2009-10-26

Family

ID=27675919

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043377A NO327937B1 (no) 2002-02-11 2004-08-13 R-(-)-1-[2-(7-klorbenzo[b]tiofen-3-yl-metoksy)-2-(2,4-diklorfenyl)-etyl]-1H-imidazol, fremgangsmate for fremstilling derav, preparat derav, samt anvendelse derav for behandling av soppinfeksjoner hos mennesker eller dyr, og bekjempelse av avlingssykdommer

Country Status (24)

Country Link
US (1) US7323433B2 (pt)
EP (1) EP1474422B1 (pt)
JP (1) JP5095070B2 (pt)
KR (1) KR100701457B1 (pt)
CN (1) CN1315824C (pt)
AT (1) ATE382618T1 (pt)
AU (1) AU2003205733B8 (pt)
BR (1) BR0307754A (pt)
CA (1) CA2474627C (pt)
CO (1) CO5601026A2 (pt)
DE (1) DE60318395T2 (pt)
DK (1) DK1474422T3 (pt)
ES (1) ES2203316B1 (pt)
IL (1) IL163452A (pt)
MX (1) MXPA04007581A (pt)
NO (1) NO327937B1 (pt)
NZ (1) NZ534464A (pt)
PL (1) PL211168B1 (pt)
PT (1) PT1474422E (pt)
RU (1) RU2276152C1 (pt)
TN (1) TNSN04140A1 (pt)
UA (1) UA78010C2 (pt)
WO (1) WO2003068770A1 (pt)
ZA (1) ZA200405941B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2249991B1 (es) * 2004-09-13 2007-03-01 Ferrer Internacional, S.A. Procedimiento de fabricacion de compuestos imidazolicos, sus sales y sus pseudopolimorfos.
ES2249992B1 (es) * 2004-09-13 2007-03-01 Ferrer Internacional, S.A. Un procedimiento para fabricar compuestos enantiomericos del imidazol.
EP1698336A1 (en) * 2005-03-01 2006-09-06 Ferrer Internacional, S.A. Antifungal compositions comprising Sertaconazole and either Hydrocortisone or an antibacterial agent
MX2011006002A (es) * 2008-12-09 2011-06-20 Ferrer Int Polimorfo ii de un compuesto antifungico.
EP2436374A1 (en) * 2010-09-30 2012-04-04 Ferrer Internacional, S.A. Ovule for vaginal administration of arasertaconazole
EP2551351A1 (en) 2011-07-29 2013-01-30 Interquim, S.A. Process for production of optically active (R)-(-)-1-(2,4-dichloro-phenyl)-2-imidazole-1-yl-ethanol
CN102440947B (zh) * 2011-11-15 2012-12-26 海南海神同洲制药有限公司 硝酸舍他康唑乳膏剂
KR101717968B1 (ko) 2016-07-18 2017-03-20 씨앤아이 주식회사 스마트폰 결합 모듈
CN113480517B (zh) * 2021-07-30 2022-09-09 海南海神同洲制药有限公司 3-溴甲基-7-氯苯并[b]噻吩的合成方法
CN113735843B (zh) * 2021-09-07 2023-05-26 海南海神同洲制药有限公司 一种低熔点硝酸舍他康唑的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1475271A (en) * 1975-04-30 1977-06-01 Pfizer Ltd 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents
US5135943A (en) * 1984-02-02 1992-08-04 Ferrer Internacional S.A. 1H-imidazole derivative compounds and pharmaceutical compositions containing the same
CA1250586A (en) * 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
US5087620A (en) * 1990-05-17 1992-02-11 Bristol-Myers Squibb Co. Controlled dermal penetration enhancement using imidazoles
KR100336642B1 (ko) * 1995-01-04 2002-11-23 페레르 인터내쇼날 에스.에이. 1-[2,4-디클로로-β-[7-클로로벤조[B]티엔-3-일)메톡시]페네틸]이미다졸모노나이트레이트의폴리모르프B및C의제조방법

Also Published As

Publication number Publication date
JP5095070B2 (ja) 2012-12-12
NZ534464A (en) 2006-02-24
JP2005524639A (ja) 2005-08-18
EP1474422B1 (en) 2008-01-02
TNSN04140A1 (en) 2007-03-12
ES2203316A1 (es) 2004-04-01
CN1315824C (zh) 2007-05-16
AU2003205733B8 (en) 2008-09-04
MXPA04007581A (es) 2004-11-10
CA2474627C (en) 2009-09-22
US7323433B2 (en) 2008-01-29
UA78010C2 (uk) 2007-02-15
KR20040079996A (ko) 2004-09-16
ATE382618T1 (de) 2008-01-15
BR0307754A (pt) 2004-12-07
DE60318395D1 (de) 2008-02-14
CA2474627A1 (en) 2003-08-21
IL163452A (en) 2011-11-30
AU2003205733A1 (en) 2003-09-04
NO20043377L (no) 2004-08-13
DK1474422T3 (da) 2008-05-13
ES2203316B1 (es) 2005-03-01
CO5601026A2 (es) 2006-01-31
PT1474422E (pt) 2008-02-28
PL211168B1 (pl) 2012-04-30
CN1630654A (zh) 2005-06-22
AU2003205733B2 (en) 2008-08-14
HK1070883A1 (en) 2005-06-30
PL370251A1 (en) 2005-05-16
EP1474422A1 (en) 2004-11-10
KR100701457B1 (ko) 2007-03-29
RU2004127573A (ru) 2006-02-10
US20050065201A1 (en) 2005-03-24
DE60318395T2 (de) 2009-01-02
RU2276152C1 (ru) 2006-05-10
ZA200405941B (en) 2006-07-26
WO2003068770A1 (en) 2003-08-21

Similar Documents

Publication Publication Date Title
CH664152A5 (fr) Derives de tetrahydrocarbazolones.
US5780642A (en) Imidazole derivatives as therapeutic agents
NO320313B1 (no) Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter, samt farmasoytisk sammensetning som innbefatter dem
NO327937B1 (no) R-(-)-1-[2-(7-klorbenzo[b]tiofen-3-yl-metoksy)-2-(2,4-diklorfenyl)-etyl]-1H-imidazol, fremgangsmate for fremstilling derav, preparat derav, samt anvendelse derav for behandling av soppinfeksjoner hos mennesker eller dyr, og bekjempelse av avlingssykdommer
DE69229057T2 (de) 1-(arylalkyl-aminoalkyl) imidazolderivate, herstellungs verfahren und verwendung als therapeutische mittel
DE69524611T2 (de) Pyrimidon-derivate
HU197315B (en) Process for producing azolyl-cyclopropyl-ethanol derivatives
CA2423259A1 (fr) Nouveaux composes derives de la quinazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP0241232B1 (en) Isoxazolylethanol derivatives
US5387599A (en) Triazoles, their production and use
US4925855A (en) Imidazole derivatives and antimycotics containing them
Botta et al. Stereospecific synthesis of 1-alkylimidazole derivatives via Mitsunobu reactions
US4812465A (en) Triazole derivatives for use as antimycotic agents
JPS61271280A (ja) 新規アゾ−ル誘導体、その製造方法と用途
RU2127277C1 (ru) Производные пропан-2-ола
HK1070883B (en) R-(-)-1-2-(7-chlorobenzo-b -thiophen-3-yl-methoxy)-2-(2,4-dichlorophenyl)ethyl -1h-imidazole
US6031109A (en) Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents
GB2175899A (en) Azole derivatives
JPH04211070A (ja) トリアゾール化合物およびその用途
JPWO1994026734A1 (ja) アゾリルアミン誘導体
JPS61109773A (ja) 光学的に活性なアゾリルカルビノール誘導体の製造方法

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees