NO843237L - Kryssbindende, poroese polymerer for kontrollert legemiddelavgivning - Google Patents

Kryssbindende, poroese polymerer for kontrollert legemiddelavgivning

Info

Publication number
NO843237L
NO843237L NO843237A NO843237A NO843237L NO 843237 L NO843237 L NO 843237L NO 843237 A NO843237 A NO 843237A NO 843237 A NO843237 A NO 843237A NO 843237 L NO843237 L NO 843237L
Authority
NO
Norway
Prior art keywords
weight
water
ethanol
swelling
crosslinking
Prior art date
Application number
NO843237A
Other languages
English (en)
Other versions
NO167360C (no
NO167360B (no
Inventor
Karl-Friedrich Mueller
Sonia Heiber
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of NO843237L publication Critical patent/NO843237L/no
Publication of NO167360B publication Critical patent/NO167360B/no
Publication of NO167360C publication Critical patent/NO167360C/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
  • Organic Insulating Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
NO843237A 1983-08-15 1984-08-14 Tverrbundede, poroese polymerer for regulert legemiddelavgivning. NO167360C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/523,236 US4548990A (en) 1983-08-15 1983-08-15 Crosslinked, porous polymers for controlled drug delivery

Publications (3)

Publication Number Publication Date
NO843237L true NO843237L (no) 1985-02-18
NO167360B NO167360B (no) 1991-07-22
NO167360C NO167360C (no) 1991-10-30

Family

ID=24084203

Family Applications (1)

Application Number Title Priority Date Filing Date
NO843237A NO167360C (no) 1983-08-15 1984-08-14 Tverrbundede, poroese polymerer for regulert legemiddelavgivning.

Country Status (16)

Country Link
US (1) US4548990A (no)
EP (1) EP0140828B1 (no)
JP (1) JPS6067435A (no)
AT (1) ATE60997T1 (no)
AU (1) AU570712B2 (no)
CA (1) CA1225030A (no)
DE (1) DE3484165D1 (no)
DK (1) DK390584A (no)
ES (1) ES8604020A1 (no)
FI (1) FI80283C (no)
GR (1) GR80109B (no)
IL (1) IL72664A (no)
NO (1) NO167360C (no)
NZ (1) NZ209213A (no)
PT (1) PT79054B (no)
ZA (1) ZA846301B (no)

Families Citing this family (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795436A (en) * 1983-11-14 1989-01-03 Bio-Mimetics, Inc. Bioadhesive composition and method of treatment therewith
US4983392A (en) * 1983-11-14 1991-01-08 Bio-Mimetics, Inc. Bioadhesive compositions and methods of treatment therewith
US4675414A (en) * 1985-03-08 1987-06-23 The United States Of America As Represented By The Secretary Of The Navy Maleimidomethyl-carbonate polyethers
ATE78404T1 (de) * 1985-05-02 1992-08-15 Ciba Geigy Ag Hydrogele mit erhoehter beladungskapazitaet bezueglich einer in einem organischen loesungsmittel loeslichen wirksubstanz, deren herstellung sowie deren verwendung.
WO1986007541A1 (fr) * 1985-06-19 1986-12-31 Yasushi Zyo Composition susceptible d'avoir une activite anti-thrombotique et appareil medical devant etre en contact avec le sang
CA1295941C (en) * 1985-08-16 1992-02-18 Rajan Bawa Sustained-release formulation comprising a hydrophobic polymer system
US4668506A (en) * 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
US4713244A (en) * 1985-08-16 1987-12-15 Bausch & Lomb Incorporated Sustained-release formulation containing an amino acid polymer with a lower alkyl (C1 -C4) polar solvent
US4783335A (en) * 1985-11-18 1988-11-08 The Kendall Company Controlled topical application of bioactive reagent
US5145675A (en) * 1986-03-31 1992-09-08 Advanced Polymer Systems, Inc. Two step method for preparation of controlled release formulations
US5879716A (en) * 1985-12-18 1999-03-09 Advanced Polymer Systems, Inc. Methods and compositions for topical delivery of benzoyl peroxide
US5955109A (en) * 1985-12-18 1999-09-21 Advanced Polymer Systems, Inc. Methods and compositions for topical delivery of retinoic acid
US4873086A (en) * 1986-03-03 1989-10-10 Ciba-Geigy Corporation Hydrogels with increased organic solvent soluble active agent loading capacity, their preparation and the use thereof
US4959217A (en) * 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
IL86211A (en) * 1987-05-04 1992-03-29 Ciba Geigy Ag Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation
US4894239A (en) * 1987-06-02 1990-01-16 Takeda Chemical Industries, Ltd. Sustained-release preparation and production thereof
US5104954A (en) * 1987-10-05 1992-04-14 Ciba-Geigy Corporation Thermostropic biphilic hydrogels and hydroplastics
US5147923A (en) * 1987-10-05 1992-09-15 Ciba-Geigy Corporation Thermotropic biphilic hydrogels and hydroplastics
US5057560A (en) * 1987-10-05 1991-10-15 Ciba-Geigy Corporation Thermotropic copolymer hydrogels from N,N-dimethylacrylamide and methoxy-ethyl (meth) acrylate
US4910015A (en) * 1987-10-19 1990-03-20 Massachusetts Institute Of Technology Surface-active polysiloxanes and drug releasing materials thereof
JPH01113322A (ja) * 1987-10-23 1989-05-02 Tomoaki Fukuda アクリル系エマルジョンおよびこれを用いたpH非依存性遅延放出型製剤
US4983668A (en) * 1987-11-25 1991-01-08 Aristech Chemical Corporation Polymer partculates for molding and the like
US5019377A (en) * 1987-12-11 1991-05-28 The Procter & Gamble Company Low glass transistion temperature adhesive copolymers for use in hair styling products
EP0347145A3 (en) * 1988-06-14 1990-10-24 University Of Utah Research Foundation Heterogeneous interpenetrating polymer networks for the controlled release of drugs
US5073381A (en) * 1988-08-15 1991-12-17 University Of Akron Amphiphilic networks
DE68914447T2 (de) * 1988-10-27 1994-10-20 Mitsui Toatsu Chemicals Verfahren zur herstellung von teilchenpolymeren.
US6017521A (en) * 1989-10-31 2000-01-25 Columbia Laboratories, Inc. Use of polycarboxylic acid polymers to treat vaginal infections
MC2204A1 (fr) * 1989-10-31 1992-11-26 Columbia Lab Inc Composition et methode d'humidification de tissus
ATE113841T1 (de) 1989-10-31 1994-11-15 Columbia Lab Inc Mittel zur feuchthaltung vaginalen gewebes.
US5120532A (en) * 1990-04-06 1992-06-09 The Procter & Gamble Company Hair styling shampoos
US5104642A (en) * 1990-04-06 1992-04-14 The Procter & Gamble Company Hair styling compositions containing particular hair styling polymers and non-aqueous solvents
US5120531A (en) * 1990-04-06 1992-06-09 The Procter & Gamble Company Hair styling conditioners
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5262450A (en) * 1990-12-28 1993-11-16 Isp Investments Inc. Abrasion and water-resistant radiation curable coatings
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
US5266331A (en) * 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
JPH0819391B2 (ja) * 1992-11-30 1996-02-28 日東電工株式会社 感圧接着剤とその接着シ―ト類
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5474985A (en) * 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
US5821313A (en) * 1995-06-19 1998-10-13 The Lubrizol Corporation Dispersant-viscosity improvers for lubricating oil compositions
US5969068A (en) 1995-06-19 1999-10-19 The Lubrizol Corporation Dispersant-viscosity improvers for lubricating oil compositions
CA2260992C (en) * 1996-08-20 2004-03-09 The Regents Of The University Of California Eye treatments using synthetic thyroid hormone compositions
CA2270975C (en) 1997-07-02 2003-04-01 Euro-Celtique, S.A. Stabilized sustained release tramadol formulations
US6124249A (en) * 1998-12-22 2000-09-26 The Lubrizol Corporation Viscosity improvers for lubricating oil compositions
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
DE19843903A1 (de) * 1998-09-24 2000-03-30 Basf Ag Feste Dosierungsform mit copolymerem Bindemittel
CN1165296C (zh) 1998-09-30 2004-09-08 Basf公司 水溶性或水可分散性含聚醚聚合物作为在药物给药形式中的包衣剂、粘合剂和/或成膜赋形剂的应用
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US6521431B1 (en) * 1999-06-22 2003-02-18 Access Pharmaceuticals, Inc. Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments
US6558607B1 (en) * 1999-09-30 2003-05-06 University Of Massachusetts Crystallization of constrained polymers
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
AU764453B2 (en) * 1999-10-29 2003-08-21 Euro-Celtique S.A. Controlled release hydrocodone formulations
US7141607B1 (en) 2000-03-10 2006-11-28 Insite Vision Incorporated Methods and compositions for treating and inhibiting retinal neovascularization
EP1315777B1 (en) 2000-09-06 2007-10-31 AP Pharma, Inc. Degradable polyacetal polymers
MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
UA81224C2 (uk) * 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US6590059B2 (en) 2001-05-11 2003-07-08 Ap Pharma, Inc. Bioerodible polyorthoesters from dioxolane-based diketene acetals
DE10128531A1 (de) * 2001-06-13 2002-12-19 Basf Ag Verwendung von wasserlöslichen oder wasserdispergierbaren Polyetherblöcke enthaltenden Pfropfpolymerisaten als Beschichtungsmittel, Matrixbildner und/oder Verpackungsmaterial für Agrochemikalien
US6921390B2 (en) 2001-07-23 2005-07-26 Boston Scientific Scimed, Inc. Long-term indwelling medical devices containing slow-releasing antimicrobial agents and having a surfactant surface
US6524606B1 (en) 2001-11-16 2003-02-25 Ap Pharma, Inc. Bioerodible polyorthoesters containing amine groups
FR2833961B1 (fr) * 2001-12-20 2004-04-02 Virsol Procede de preparation de films a base de poly(oxyde d'ethylene) reticule
GB0205868D0 (en) * 2002-03-13 2002-04-24 Univ Nottingham Polymer composite with internally distributed deposition matter
ES2661168T3 (es) 2003-07-12 2018-03-27 Accelerate Diagnostics, Inc. Biodetección sensible y rápida
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
EP2455382B1 (en) 2005-12-13 2016-10-26 Incyte Holdings Corporation Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
US20080069871A1 (en) * 2006-07-21 2008-03-20 Vaughn Jason M Hydrophobic abuse deterrent delivery system
EP3070090B1 (en) 2007-06-13 2018-12-12 Incyte Holdings Corporation Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
US20090005362A1 (en) * 2007-06-26 2009-01-01 Vo Toan P Compositions Comprising Antihistamines or Mast Cell Stabilizers, and Methods of Making and Using Same
US7795231B2 (en) 2007-10-04 2010-09-14 Insite Vision Incorporated Concentrated aqueous azalide formulations
US8158616B2 (en) 2008-03-11 2012-04-17 Incyte Corporation Azetidine and cyclobutane derivatives as JAK inhibitors
GB0812742D0 (en) * 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
CL2009001884A1 (es) * 2008-10-02 2010-05-14 Incyte Holdings Corp Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco.
US8501800B2 (en) * 2009-03-05 2013-08-06 Insite Vision Incorporated Controlled-release ophthalmic vehicles
US8778999B2 (en) 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
US10201548B2 (en) 2009-03-06 2019-02-12 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
US20170128481A9 (en) 2009-03-06 2017-05-11 Insite Vision Corporation Ocular treatment with reduced intraocular pressure
US10980818B2 (en) 2009-03-06 2021-04-20 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
US8513353B2 (en) 2009-03-19 2013-08-20 Agency For Science, Technology And Research Forming copolymer from bicontinuous microemulsion comprising monomers of different hydrophilicity
JP5775070B2 (ja) 2009-05-22 2015-09-09 インサイト・コーポレイションIncyte Corporation ヤヌスキナーゼ阻害剤としてのピラゾール−4−イル−ピロロ[2,3−d]ピリミジンおよびピロール−3−イル−ピロロ[2,3−d]ピリミジンのN−(ヘテロ)アリール−ピロリジン誘導体
SG176111A1 (en) * 2009-05-22 2011-12-29 Incyte Corp 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
US8563760B2 (en) * 2009-08-31 2013-10-22 Mayo Foundation For Medical Education And Research Process for the synthesis of long-chain fatty acids
AR078012A1 (es) 2009-09-01 2011-10-05 Incyte Corp Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus
PT3354652T (pt) 2010-03-10 2020-07-20 Incyte Holdings Corp Derivados de piperidin-4-ilazetidina como inibidores de jak1
RS54824B1 (sr) 2010-05-21 2016-10-31 Incyte Holdings Corp Topikalna formulacija za inhibiciju jak-a
CA2818542A1 (en) 2010-11-19 2012-05-24 Incyte Corporation Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
WO2012068440A1 (en) 2010-11-19 2012-05-24 Incyte Corporation Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
WO2012122314A2 (en) 2011-03-07 2012-09-13 Accelr8 Technology Corporation Rapid cell purification systems
MY165963A (en) 2011-06-20 2018-05-18 Incyte Holdings Corp Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
TW201313721A (zh) 2011-08-18 2013-04-01 Incyte Corp 作為jak抑制劑之環己基氮雜環丁烷衍生物
UA111854C2 (uk) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak
FR2987561B1 (fr) * 2012-03-02 2014-04-11 Pf Medicament Dispositif transdermique comprenant des micro-particules poreuses
TW201406761A (zh) 2012-05-18 2014-02-16 Incyte Corp 做爲jak抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物
BR112015010360A8 (pt) 2012-11-08 2018-01-16 Eleven Biotherapeutics Inc antagonistas de il-6 e utilização dos mesmos.
CN113384546A (zh) 2012-11-15 2021-09-14 因赛特公司 鲁索利替尼的缓释剂型
WO2014107737A2 (en) 2013-01-07 2014-07-10 Eleven Biotherapeutics, Inc. Local delivery of il-17 inhibitors for treating ocular disease
WO2014138168A1 (en) 2013-03-06 2014-09-12 Incyte Corporation Processes and intermediates for making a jak inhibitor
US9044508B2 (en) 2013-03-15 2015-06-02 Insite Vision Corporation Concentrated aqueous azalide formulations
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
SG10201801069QA (en) 2013-08-07 2018-03-28 Incyte Corp Sustained release dosage forms for a jak1 inhibitor
EP3119392A4 (en) 2014-03-17 2017-10-11 Encompass Development Inc. Ocular formulations
US9498467B2 (en) 2014-05-30 2016-11-22 Incyte Corporation Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
WO2016073894A1 (en) 2014-11-07 2016-05-12 Eleven Biotherapeutics, Inc. Therapeutic agents with increased ocular retention
PT3215530T (pt) 2014-11-07 2019-11-21 Sesen Bio Inc Anticorpos de il-6 melhorados
AU2016243656A1 (en) 2015-03-30 2017-11-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
JP2018522070A (ja) 2015-07-27 2018-08-09 キャタコア・インコーポレイテッドCatacore, Inc. 白内障の処置用組成物
EP3419599A4 (en) 2016-02-23 2019-09-11 Sesen Bio, Inc. IL-6 ANTAGONIST FORMULATIONS AND USE THEREOF
AR113922A1 (es) 2017-12-08 2020-07-01 Incyte Corp Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas
EA202091830A1 (ru) 2018-01-30 2020-12-29 Инсайт Корпорейшн Способы и промежуточные соединения для получения ингибитора jak
MD3773593T2 (ro) 2018-03-30 2024-10-31 Incyte Corp Tratament hidradenitei supurative utilizând inhibitori ai JAK
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
KR102151051B1 (ko) 2019-01-10 2020-09-02 고려대학교 산학협력단 당뇨병성 백내장 치료 또는 예방용 조성물
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms
WO2026063344A1 (ja) * 2024-09-20 2026-03-26 Jsr株式会社 多孔質粒子の製造方法及び精製又は吸着用担体の製造方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297357A (no) * 1962-08-31
CH468192A (de) * 1964-06-19 1969-02-15 Ciba Geigy Verfahren zur Herstellung von Arzneimitteln in Perlenform
US3538214A (en) * 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
US4184020A (en) * 1970-11-24 1980-01-15 Ceskoslovenska Akademie Ved Preparation of hydrophilic material for gel chromatography
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
GB1456365A (en) * 1972-10-06 1976-11-24 Gist Brocades Nv Controlled release composition
US4192827A (en) * 1974-06-27 1980-03-11 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers
US4177056A (en) * 1974-06-27 1979-12-04 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers used as carriers for medicaments and pesticides
HU174057B (hu) * 1976-09-17 1979-10-28 Richter Gedeon Vegyeszet Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva
US4136250A (en) * 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4224427A (en) * 1978-06-01 1980-09-23 Ciba-Geigy Corporation Process for preparing hydrogels as spherical beads of large size
US4379864A (en) * 1979-02-09 1983-04-12 Syntex (U.S.A.) Inc. Polymeric compositions and hydrogels formed therefrom
JPS55149212A (en) * 1979-05-11 1980-11-20 Toray Ind Inc Gradually releasing preparation of methotrexate

Also Published As

Publication number Publication date
FI843190A0 (fi) 1984-08-13
IL72664A (en) 1988-03-31
FI843190A7 (fi) 1985-02-16
FI80283B (fi) 1990-01-31
DK390584D0 (da) 1984-08-14
EP0140828A3 (en) 1987-02-04
DK390584A (da) 1985-02-16
ATE60997T1 (de) 1991-03-15
ZA846301B (en) 1985-05-29
US4548990A (en) 1985-10-22
EP0140828A2 (de) 1985-05-08
AU570712B2 (en) 1988-03-24
NO167360C (no) 1991-10-30
JPS6067435A (ja) 1985-04-17
IL72664A0 (en) 1984-11-30
CA1225030A (en) 1987-08-04
NO167360B (no) 1991-07-22
PT79054B (en) 1987-06-03
FI80283C (fi) 1990-05-10
GR80109B (en) 1984-12-14
DE3484165D1 (de) 1991-04-04
NZ209213A (en) 1986-12-05
ES8604020A1 (es) 1986-01-16
ES535129A0 (es) 1986-01-16
EP0140828B1 (de) 1991-02-27
AU3189684A (en) 1985-02-21
PT79054A (en) 1984-09-01

Similar Documents

Publication Publication Date Title
NO843237L (no) Kryssbindende, poroese polymerer for kontrollert legemiddelavgivning
KR950005301A (ko) 방출 개시 제어 및 방출 속도 제어형 제제
EP0111144B1 (en) Sustained release solid dosage forms having non-uniform distribution of active ingredient
CA2290624A1 (en) Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
AU722741B2 (en) Controlled release tablet
CA2037410A1 (en) Therapeutic compositions with controlled release of medicaments supported on crosslinked polymers and coated with polymer films, and their preparation process
EP0250374B1 (en) Therapeutic system for controlled release of drugs
IE781163L (en) Sustained release of veterinary medicaments
KR870000069A (ko) 안정한 고체 제형의 제조 방법
CA2364845A1 (en) Extending the duration of drug release within the stomach during the fed mode
KR880008800A (ko) 난용성 활성성분을 위한 치료계
DE69636223D1 (de) Formulierung mit gesteuerter freisetzung für wasserlöslische arzneistoffe, in der eine auslauföffnung in situ gebildet wird
BR0113570A (pt) Cápsula rìgida
DK493689A (da) Topisk ophthalmisk laegemiddel
ATE29386T1 (de) Verwendung eines sulfonierten homo- oder copolymeren des styrols zur herstellung eines antikonzeptionsmittels.
Bae et al. Heterogeneous interpenetrating polymer networks for drug delivery
EP0190996A3 (en) Crosslinked, porous polymers for controlled delivery of agricultural ingredients
KR100245546B1 (ko) 점막 점착성 고분자 복합체 및 그의 제조방법
JPS5688405A (en) Preparation of vinyl chloride polymer
JPS55149212A (en) Gradually releasing preparation of methotrexate
JPS57130907A (en) Amlgam coating agent
JPS577415A (en) Fomentation