NO863305L - Fremgangsmaate for fremstilling av en stabil modifikasjon av torasemid. - Google Patents

Fremgangsmaate for fremstilling av en stabil modifikasjon av torasemid.

Info

Publication number: NO863305L
Authority: NO; Norway
Prior art keywords: torasemide; procedure; manufacturing; stable modification; modification
Prior art date: 1985-08-17

Application number

NO863305A

Other languages

English (en)

Other versions

NO170079C (no

NO170079B (no

NO863305D0 (no

Inventor

Fritz Topfmeier

Gustav Lettenbauer

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-17

Filing date

1986-08-15

Publication date

1987-02-18

1986-08-15 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1986-08-15 Publication of NO863305D0 publication Critical patent/NO863305D0/no

1987-02-18 Publication of NO863305L publication Critical patent/NO863305L/no

1992-06-01 Publication of NO170079B publication Critical patent/NO170079B/no

1992-09-09 Publication of NO170079C publication Critical patent/NO170079C/no

Links

NGBFQHCMQULJNZ-UHFFFAOYSA-N Torsemide Chemical compound CC(C)NC(=O)NS(=O)(=O)C1=CN=CC=C1NC1=CC=CC(C)=C1 NGBFQHCMQULJNZ-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
238000012986 modification Methods 0.000 title 1
230000004048 modification Effects 0.000 title 1
229960005461 torasemide Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Hematology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Compounds Of Unknown Constitution (AREA)
Saccharide Compounds (AREA)

NO863305A 1985-08-17 1986-08-15 Fremgangsmaate for fremstilling av et krystallinsk torasemid NO170079C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19853529529 DE3529529A1 (de)	1985-08-17	1985-08-17	Verfahren zur herstellung einer stabilen modifikation von torasemid

Publications (4)

Publication Number	Publication Date
NO863305D0 NO863305D0 (no)	1986-08-15
NO863305L true NO863305L (no)	1987-02-18
NO170079B NO170079B (no)	1992-06-01
NO170079C NO170079C (no)	1992-09-09

Family

ID=6278766

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO863305A NO170079C (no)	1985-08-17	1986-08-15	Fremgangsmaate for fremstilling av et krystallinsk torasemid

Country Status (25)

Country	Link
US (4)	US4743693A (no)
EP (1)	EP0212537B1 (no)
JP (2)	JPS6245576A (no)
KR (1)	KR930009818B1 (no)
AU (1)	AU573454B2 (no)
CA (1)	CA1307277C (no)
CS (2)	CS259891B2 (no)
DD (1)	DD259858A5 (no)
DE (2)	DE3529529A1 (no)
DK (1)	DK162518C (no)
ES (1)	ES2001522A6 (no)
FI (1)	FI82189C (no)
GR (1)	GR862139B (no)
HK (1)	HK59994A (no)
HU (1)	HU195778B (no)
IE (1)	IE59237B1 (no)
IL (1)	IL79672A (no)
LT (1)	LT3596B (no)
NO (1)	NO170079C (no)
NZ (1)	NZ217172A (no)
PL (1)	PL146086B1 (no)
PT (1)	PT83186B (no)
SU (1)	SU1480766A3 (no)
UA (1)	UA7080A1 (no)
ZA (1)	ZA866151B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3623620A1 (de) *	1986-07-12	1988-01-21	Boehringer Mannheim Gmbh	Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung
US5166162A (en) *	1990-03-02	1992-11-24	Adir Et Compagnie	Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
JP3586471B2 (ja) *	1991-06-25	2004-11-10	三菱ウェルファーマ株式会社	トラセミド含有医薬組成物
TW257757B (no) *	1993-03-03	1995-09-21	Boehringer Mannheim Gmbh
HRP980532B1 (en) *	1998-10-02	2005-06-30	Pliva	Novel crystalline torasemide modification
US6166045A (en)	1998-06-02	2000-12-26	Roche Diagnostics Gmbh	Torasemide of modification III
US5914336A (en)	1998-06-02	1999-06-22	Boehringer Mannheim Gmbh	Method of controlling the serum solubility of orally administered torasemide and composition relating thereto
US20030026835A1 (en) *	1999-02-15	2003-02-06	Sumitomo Pharmaceuticals Company Limited	Tablets disintegrating rapidly in the oral cavity
CN1378448A (zh) *	1999-08-11	2002-11-06	特瓦制药工业有限公司	多晶型托拉塞米
TR200401462T4 (tr)	2000-02-17	2004-08-23	Teva Pharmaceutical Industries Ltd.	Torsemid modifikasyonu II' yi içeren dengeli bir farmasötik formülasyonu
HRP20020819A2 (en)	2000-03-20	2004-12-31	Teva Pharma	Novel processes for preparing torsemide intermediate
HRP20000162B1 (en) *	2000-03-20	2004-06-30	Pliva D D	Amorphous torasemide modification
HRP20000765A2 (en) *	2000-11-10	2002-06-30	Pliva D D	Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release
US20030022921A1 (en) *	2001-02-21	2003-01-30	Minutza Leibovici	Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (no) *	2001-08-03	2004-03-06	Ranbaxy Lab
EP2316468A1 (en)	2002-02-22	2011-05-04	Shire LLC	Delivery system and methods for protecting and administering dextroamphetamine
ITMI20020639A1 (it) *	2002-03-27	2003-09-29	Cosma S P A	Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea
HRP20020603B1 (en) *	2002-07-19	2008-11-30	Pliva D.D.	New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
ES2237354T3 (es) *	2002-11-18	2007-11-01	Teva Pharmaceutical Industries Ltd.	Lansoprazol estable que contiene mas de 500 ppm, hasta aproximadamente 3.000 ppm de agua y mas de 200 ppm, hasta aproximadamente 5.000 ppm de alcohol.
CA2515130A1 (en) *	2003-02-05	2004-08-26	Teva Pharmaceutical Industries Ltd.	Method of stabilizing lansoprazole
ES2244324B1 (es) *	2004-03-25	2006-11-16	Ferrer Internacional, S.A.	Composiciones diureticas de liberacion prolongada.
AT500576B1 (de) *	2004-07-28	2006-11-15	Sanochemia Pharmazeutika Ag	Verfahren zur reindarstellung von kristallformen von torsemid
US10178893B1 (en) *	2013-06-14	2019-01-15	Scott Bradley Baker	Shoe
FR3018688A1 (fr) *	2014-03-19	2015-09-25	Virbac	Utilisation de torasemide a faible dose dans une composition veterinaire
EP3031471A1 (en)	2014-12-12	2016-06-15	Ceva Sante Animale	Veterinary composition for the treatment of pulmonary edema associated with heart failure in domestic animals
US12048677B2 (en)	2014-12-12	2024-07-30	Ceva Sante Animale	Compositions and uses thereof for the treatment of heart failure in domestic animals
DK3173075T3 (en) *	2015-11-27	2019-01-21	Accupharma Spolka Z Ograniczona Odpowiedzialnoscia	PHARMACEUTICAL COMBINATION PREPARATION OF ACE INHIBITOR AND LOOPDIURETIC
CN115417810B (zh) *	2022-09-22	2023-10-10	南京正科医药股份有限公司	一种托拉塞米晶型ⅰ的精制方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US30633A (en) *		1860-11-13		Improvement in fire-escapes
GB1477664A (en) *	1974-04-17	1977-06-22	Christiaens Sa A	Pyridine derivatives
GB1593609A (en) *	1978-01-31	1981-07-22	Christiaens Sa A	Pyridine sulfonamides
LU85193A1 (fr) *	1984-01-31	1985-09-12	Christiaens Sa A	Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation

1985
- 1985-08-17 DE DE19853529529 patent/DE3529529A1/de active Granted
1986
- 1986-08-10 IL IL79672A patent/IL79672A/xx not_active IP Right Cessation
- 1986-08-11 AU AU61055/86A patent/AU573454B2/en not_active Expired
- 1986-08-11 CA CA000515676A patent/CA1307277C/en not_active Expired - Lifetime
- 1986-08-11 CS CS865945A patent/CS259891B2/cs not_active IP Right Cessation
- 1986-08-11 US US06/895,355 patent/US4743693A/en not_active Ceased
- 1986-08-12 PT PT83186A patent/PT83186B/pt unknown
- 1986-08-12 EP EP86111118A patent/EP0212537B1/de not_active Expired - Lifetime
- 1986-08-12 NZ NZ217172A patent/NZ217172A/xx unknown
- 1986-08-12 DE DE8686111118T patent/DE3667970D1/de not_active Expired - Lifetime
- 1986-08-13 DK DK385586A patent/DK162518C/da not_active IP Right Cessation
- 1986-08-13 IE IE217986A patent/IE59237B1/en not_active IP Right Cessation
- 1986-08-14 KR KR1019860006689A patent/KR930009818B1/ko not_active Expired - Lifetime
- 1986-08-14 GR GR862139A patent/GR862139B/el unknown
- 1986-08-14 DD DD86293655A patent/DD259858A5/de not_active IP Right Cessation
- 1986-08-14 ES ES8601131A patent/ES2001522A6/es not_active Expired
- 1986-08-15 SU SU864027953A patent/SU1480766A3/ru active
- 1986-08-15 ZA ZA866151A patent/ZA866151B/xx unknown
- 1986-08-15 NO NO863305A patent/NO170079C/no not_active IP Right Cessation
- 1986-08-15 PL PL1986261052A patent/PL146086B1/pl unknown
- 1986-08-15 FI FI863305A patent/FI82189C/fi not_active IP Right Cessation
- 1986-08-15 HU HU863598A patent/HU195778B/hu unknown
- 1986-08-15 UA UA4027953A patent/UA7080A1/uk unknown
- 1986-08-18 JP JP61191789A patent/JPS6245576A/ja active Granted
1987
- 1987-10-20 US US07/111,439 patent/US4822807A/en not_active Ceased
1989
- 1989-10-27 JP JP1278800A patent/JPH0643400B2/ja not_active Expired - Lifetime
1991
- 1991-12-31 CS CS914199A patent/CS419991A3/cs unknown
1992
- 1992-12-03 US US07/985,053 patent/USRE34580E/en not_active Expired - Lifetime
1993
- 1993-04-08 US US08/043,631 patent/USRE34672E/en not_active Expired - Lifetime
- 1993-08-27 LT LTIP898A patent/LT3596B/lt not_active IP Right Cessation
1994
- 1994-06-23 HK HK59994A patent/HK59994A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI82189B (fi)	1990-10-31
UA7080A1 (uk)	1995-06-30
US4743693A (en)	1988-05-10
IE59237B1 (en)	1994-01-26
IL79672A0 (en)	1986-11-30
DE3529529C2 (no)	1987-05-27
DK385586D0 (da)	1986-08-13
FI863305L (fi)	1987-02-18
AU573454B2 (en)	1988-06-09
JPH0415205B2 (no)	1992-03-17
PT83186A (de)	1986-09-01
JPS6245576A (ja)	1987-02-27
DK162518C (da)	1992-03-30
NO170079C (no)	1992-09-09
AU6105586A (en)	1987-02-19
JPH02191255A (ja)	1990-07-27
PL146086B1 (en)	1988-12-31
DK385586A (da)	1987-02-18
FI863305A0 (fi)	1986-08-15
LT3596B (en)	1995-12-27
US4822807A (en)	1989-04-18
IL79672A (en)	1990-01-18
USRE34672E (en)	1994-07-26
JPH0643400B2 (ja)	1994-06-08
IE862179L (en)	1987-02-17
EP0212537B1 (de)	1990-01-03
USRE34580E (en)	1994-04-05
KR930009818B1 (ko)	1993-10-11
KR870002076A (ko)	1987-03-30
NZ217172A (en)	1989-02-24
ZA866151B (en)	1987-04-29
FI82189C (fi)	1991-02-11
NO170079B (no)	1992-06-01
CS259891B2 (en)	1988-11-15
DE3667970D1 (de)	1990-02-08
DE3529529A1 (de)	1987-02-19
DD259858A5 (de)	1988-09-07
CS419991A3 (en)	1992-06-17
DK162518B (da)	1991-11-11
HU195778B (en)	1988-07-28
EP0212537A1 (de)	1987-03-04
PT83186B (pt)	1988-07-01
PL261052A1 (en)	1987-11-02
GR862139B (en)	1986-12-30
NO863305D0 (no)	1986-08-15
LTIP898A (en)	1995-03-27
CA1307277C (en)	1992-09-08
ES2001522A6 (es)	1988-06-01
HUT42069A (en)	1987-06-29
HK59994A (en)	1994-07-08
CS594586A2 (en)	1988-03-15
SU1480766A3 (ru)	1989-05-15

Legal Events

Date	Code	Title	Description
2006-08-21	MK1K	Patent expired

Publication	Publication Date	Title
NO863305D0 (no)	1986-08-15	Fremgangsmaate for fremstilling av en stabil modifikasjon av torasemid.
NO163227C (no)	1990-04-25	Fremgangsm te for fremstilling av 1-substituert-aryihydro-4-oksonaftyridin-derivater.
FI89071B (fi)	1993-04-30	Ny ytaktiv komposition, foerfarande foer framstaellning av densamma och dess anvaendning
NO864368L (no)	1987-05-04	Fremgangsmaate for fremstilling av et vaskepulver.
OA08484A (fr)	1988-07-29	Pesticidal polyhaloalkene derivatives.
NO862797D0 (no)	1986-07-10	Fremstilling av alumoxaner.
NO167034C (no)	1991-09-25	Fremgangsmaate for fremstilling av 1,6-diklor-1,6-dideoksy-beta-d-fruktofuranosyl-4-kloro-4-dioksy-alfa-galactopyranosid
NO861114L (no)	1986-09-26	Fremgangsmaate for fremstilling av polyisocyanat-polyisocyanurater.
FI861755A0 (fi)	1986-04-25	Foerfarande foer framstaellning av hydroklorid av 1-fenyl-1-dietylaminokarbonyl- 2-aminometylcyklopropan (z).
NO163097C (no)	1990-04-04	Fremgangsmaate ved fremstilling av urea.
NO863212L (no)	1987-02-13	Fremgangsmaate ved fremstilling av urea.
NO855356L (no)	1986-07-15	Fremgangsmaate ved fremstilling av cefem-derivater.
FI862638L (fi)	1986-12-29	Belastningsbegraensande anordning foer a/d-omformare av urladdningstyp.
FI864586A7 (fi)	1986-11-11	Cementartad komposition av alkalimetallbundet kvarts.
FI853938A0 (fi)	1985-10-10	Anordning foer profilmaetning av raelshjul.
NO863306D0 (no)	1986-08-15	Fremgangsmaate for fremstilling av en stabil kulltjaereholdig sjampo.
NO167159C (no)	1991-10-09	Fremgangsmaate for fremstilling av cellulosemasse.
FI860247A0 (fi)	1986-01-20	Foerfarande foer framstaellning av 4,4-dialkyl-2-azetidinoner.
FI863883A0 (fi)	1986-09-25	Anordning foer tillslutning av flaskhals.
FI865342A0 (fi)	1986-12-30	Foerbaettringar i spiralblandare avsedda foer maskiner foer framstaellning av betonghaolplattor.
FI864790A0 (fi)	1986-11-25	Foerfarande foer framstaellning av 5-klor- och 5-brom-2-hydroxinikotinsyror.
NO851774L (no)	1985-11-05	Fremgangsmaate for fremstilling av en 2-oksindol-1-karboksamid-forbindelse.
RO91180A2 (ro)	1987-04-30	Procedeu pentru prepararea 10,11/dihidro-n-metil-n-carbotoxi-5h-dibenzo(a,d)-ciclohepten delta 5 gama-propilaminei
FI864736A0 (fi)	1986-11-20	Foerfarande foer framstaellning av 2-substituerade 5-nitroso-4,6-diamino-pyrimidiner.
NO862088L (no)	1986-12-01	Fremgangsmaate for fremstilling av tverrbundne produkter.