NO865323L - Antibiotisk virksomme a40926 n-acylaminoglukuronyl-aglykoner, antibiotikum a40926 aglykon, samt fremgangsmaater for fremstilling av disse stoffene. - Google Patents

Antibiotisk virksomme a40926 n-acylaminoglukuronyl-aglykoner, antibiotikum a40926 aglykon, samt fremgangsmaater for fremstilling av disse stoffene.

Info

Publication number: NO865323L
Authority: NO; Norway
Prior art keywords: antibiotic; aglycon; acylaminoglucuronyl; factor; substances
Prior art date: 1986-04-11

Application number

NO865323A

Other languages

English (en)

Other versions

NO172121B (no

NO172121C (no

Inventor

Enrico Selva

Ernesto Riva

Giovanni Cassani

Francesco Parenti

Original Assignee

Lepetit Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-11

Filing date

1986-12-29

Publication date

1987-10-12

1986-12-29 Application filed by Lepetit Spa filed Critical Lepetit Spa

1987-10-12 Publication of NO865323L publication Critical patent/NO865323L/no

1993-03-01 Publication of NO172121B publication Critical patent/NO172121B/no

1993-06-09 Publication of NO172121C publication Critical patent/NO172121C/no

Links

BEVDFPMXVNOQBI-AXNWEOKVSA-N (19R,22R,34S,37R,40R,52S)-64-[(2S,3R,4R,5S,6S)-3-amino-6-carboxy-4,5-dihydroxyoxan-2-yl]oxy-5,32-dichloro-2,26,31,49-tetrahydroxy-22-(methylamino)-21,35,38,54,56,59-hexaoxo-47-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo[38.14.2.23,6.214,17.219,34.18,12.123,27.129,33.141,45.010,37.046,51]hexahexaconta-3,5,8,10,12(64),14(63),15,17(62),23(61),24,26,29(60),30,32,41,43,45(57),46(51),47,49,65-henicosaene-52-carboxylic acid Chemical compound CN[C@@H]1c2ccc(O)c(Oc3cc(O)c(Cl)c(c3)[C@@H]3NC(=O)[C@@H](Cc4ccc(Oc5cc6cc(Oc7ccc(cc7Cl)C(O)C7NC(=O)[C@H](NC(=O)[C@@H]6NC3=O)c3cccc(c3)-c3c(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)cc(O)cc3[C@H](NC7=O)C(O)=O)c5O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3N)C(O)=O)cc4)NC1=O)c2 BEVDFPMXVNOQBI-AXNWEOKVSA-N 0.000 title abstract 8
DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 title abstract 7
230000003115 biocidal effect Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
239000000126 substance Substances 0.000 title abstract 2
208000035473 Communicable disease Diseases 0.000 abstract 1
102000003712 Complement factor B Human genes 0.000 abstract 1
108090000056 Complement factor B Proteins 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)
Medicinal Preparation (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO865323A 1986-04-11 1986-12-29 Analogifremgangsmaate for fremstilling av antibiotisk virksomme a 40926 n-acylaminoglukuronyl-aglykoner og antibiotikum a 40926 aglykon NO172121C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868608809A GB8608809D0 (en)	1986-04-11	1986-04-11	Antibiotic

Publications (3)

Publication Number	Publication Date
NO865323L true NO865323L (no)	1987-10-12
NO172121B NO172121B (no)	1993-03-01
NO172121C NO172121C (no)	1993-06-09

Family

ID=10596024

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO865323A NO172121C (no)	1986-04-11	1986-12-29	Analogifremgangsmaate for fremstilling av antibiotisk virksomme a 40926 n-acylaminoglukuronyl-aglykoner og antibiotikum a 40926 aglykon

Country Status (22)

Country	Link
US (1)	US4868171A (no)
EP (1)	EP0240609B1 (no)
JP (1)	JPH0759593B2 (no)
KR (2)	KR950010461B1 (no)
CN (1)	CN1033043C (no)
AT (1)	ATE70069T1 (no)
AU (1)	AU601706B2 (no)
DE (1)	DE3682767D1 (no)
DK (1)	DK167770B1 (no)
ES (1)	ES2040207T3 (no)
FI (1)	FI86307C (no)
GB (1)	GB8608809D0 (no)
GR (1)	GR3003443T3 (no)
HU (1)	HU196229B (no)
IE (1)	IE59523B1 (no)
IL (1)	IL81106A (no)
MY (1)	MY101178A (no)
NO (1)	NO172121C (no)
NZ (1)	NZ218789A (no)
PH (1)	PH23620A (no)
PT (1)	PT84029B (no)
ZA (1)	ZA869713B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK363587A (da) *	1986-07-30	1988-01-31	Smithkline Beckman Corp	Antibiotika og fremstilling heraf under anvendelseaf actinomadura parvosata
GB8621912D0 (en) *	1986-09-11	1986-10-15	Lepetit Spa	Increasing ratio of components of anti-biotic complex
ES2084595T3 (es) *	1988-12-27	1996-05-16	Lepetit Spa	Procedimiento quimico mejorado para preparar el antibiotico l/17392 (desglucoteicoplanina) y sus sales.
ATE134379T1 (de) *	1990-12-05	1996-03-15	Lepetit Spa	38-decarboxy-38-hydroxymethylderivate von teicoplaninantibiotika, und verfahren zu deren herstellung
US5606036A (en) *	1991-03-27	1997-02-25	Gruppo Lepetit Spa	Antibiotic A 40926 ester derivatives
JP3314930B2 (ja)	1991-03-27	2002-08-19	バイオサーチ・イタリア・ソチエタ・ペル・アチオニ	抗生物質ａ４０９２６エステル誘導体
US5750509A (en) *	1991-07-29	1998-05-12	Gruppo Lepetit S.P.A.	Amide derivatives of antibiotic A 40926
DK0596929T3 (da) *	1991-07-29	1995-09-11	Lepetit Spa	Amidderivater af antibiotikum A 40926
AU701463B2 (en) *	1995-07-05	1999-01-28	Sanofi Aventis S.P.A.	Purification of dalbaheptide antibiotics by isoelectric focusing
DK0912604T3 (da)	1996-04-23	2002-03-25	Biosearch Italia Spa	Forbedret kemisk fremgangsmåde til fremstilling af amidderivater af A 40926 antibiotikum
US7119061B2 (en)	2002-11-18	2006-10-10	Vicuron Pharmaceuticals, Inc.	Dalbavancin compositions for treatment of bacterial infections
EP1565201B1 (en) *	2002-11-18	2018-10-31	Vicuron Pharmaceuticals, Inc.	Methods of administering dalbavancin for treatment of bacterial infections
US20060074014A1 (en) *	2002-11-18	2006-04-06	Vicuron Pharmaceuticals Inc.	Dalbavancin compositions for treatment of bacterial infections
CN101851277B (zh) *	2009-03-12	2012-10-03	成都雅途生物技术有限公司	一种道古霉素关键中间体a40926 bo组分的纯化制备方法
CN102417919B (zh) *	2011-09-02	2017-05-24	山东鲁抗医药股份有限公司	一种发酵法生产高纯度替考拉宁的方法
CN110105435B (zh) *	2019-05-08	2023-12-08	宜昌东阳光生化制药有限公司	一种生产a40926的发酵培养基和发酵方法
CN112625925B (zh) *	2021-01-08	2022-04-19	浙江大学	一种达巴万星前体a40926b0高产菌株及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI75190C (fi) *	1982-03-24	1988-05-09	Lilly Co Eli	Foerfarande foer framstaellning av ett antibiotikum a41030-komplex eller dess faktorer a, b, c, d, e, f och g.
GB8307847D0 (en) *	1983-03-22	1983-04-27	Lepetit Spa	Antibiotics l 17054 and l 17046
US4521335A (en) *	1983-07-13	1985-06-04	Smithkline Beckman Corporation	Aglycone and pseudo-aglycones of the AAD 216 antibiotics
AU579120B2 (en) *	1983-12-16	1988-11-17	Gruppo Lepetit S.P.A.	Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
GB8425685D0 (en) *	1984-10-11	1984-11-14	Lepetit Spa	Antibiotic a 40926 complex

1986
- 1986-04-11 GB GB868608809A patent/GB8608809D0/en active Pending
- 1986-12-15 EP EP86117452A patent/EP0240609B1/en not_active Expired - Lifetime
- 1986-12-15 AT AT86117452T patent/ATE70069T1/de not_active IP Right Cessation
- 1986-12-15 ES ES198686117452T patent/ES2040207T3/es not_active Expired - Lifetime
- 1986-12-15 DE DE8686117452T patent/DE3682767D1/de not_active Expired - Lifetime
- 1986-12-19 DK DK617286A patent/DK167770B1/da not_active IP Right Cessation
- 1986-12-23 NZ NZ218789A patent/NZ218789A/xx unknown
- 1986-12-23 US US06/945,639 patent/US4868171A/en not_active Expired - Fee Related
- 1986-12-23 AU AU66883/86A patent/AU601706B2/en not_active Ceased
- 1986-12-23 IE IE338286A patent/IE59523B1/en not_active IP Right Cessation
- 1986-12-26 IL IL81106A patent/IL81106A/xx not_active IP Right Cessation
- 1986-12-29 JP JP61315965A patent/JPH0759593B2/ja not_active Expired - Lifetime
- 1986-12-29 ZA ZA869713A patent/ZA869713B/xx unknown
- 1986-12-29 PT PT84029A patent/PT84029B/pt not_active IP Right Cessation
- 1986-12-29 KR KR1019860011488A patent/KR950010461B1/ko not_active Expired - Fee Related
- 1986-12-29 FI FI865320A patent/FI86307C/fi not_active IP Right Cessation
- 1986-12-29 NO NO865323A patent/NO172121C/no unknown
- 1986-12-29 HU HU865504A patent/HU196229B/hu not_active IP Right Cessation
- 1986-12-30 CN CN86108977A patent/CN1033043C/zh not_active Expired - Fee Related
1987
- 1987-01-12 PH PH34710A patent/PH23620A/en unknown
- 1987-04-01 MY MYPI87000414A patent/MY101178A/en unknown
- 1987-07-01 KR KR1019870006804A patent/KR960010557B1/ko not_active Expired - Fee Related
1991
- 1991-12-27 GR GR91402185T patent/GR3003443T3/el unknown

Also Published As

Publication number	Publication date
GR3003443T3 (en)	1993-02-17
AU6688386A (en)	1987-10-15
FI86307B (fi)	1992-04-30
IL81106A (en)	1992-07-15
NO172121B (no)	1993-03-01
DK617286A (da)	1987-10-12
IE863382L (en)	1987-10-11
JPS62242699A (ja)	1987-10-23
KR950010461B1 (ko)	1995-09-18
NO172121C (no)	1993-06-09
JPH0759593B2 (ja)	1995-06-28
HUT43869A (en)	1987-12-28
HU196229B (en)	1988-10-28
DK617286D0 (da)	1986-12-19
FI86307C (fi)	1992-08-10
PT84029B (pt)	1989-01-17
EP0240609B1 (en)	1991-12-04
AU601706B2 (en)	1990-09-20
KR890002231A (ko)	1989-04-08
PT84029A (en)	1987-01-01
FI865320L (fi)	1987-10-12
MY101178A (en)	1991-07-31
ZA869713B (en)	1987-12-30
FI865320A0 (fi)	1986-12-29
CN86108977A (zh)	1988-04-27
IL81106A0 (en)	1987-03-31
DK167770B1 (da)	1993-12-13
US4868171A (en)	1989-09-19
EP0240609A2 (en)	1987-10-14
DE3682767D1 (de)	1992-01-16
ATE70069T1 (de)	1991-12-15
KR960010557B1 (ko)	1996-08-02
ES2040207T3 (es)	1993-10-16
CN1033043C (zh)	1996-10-16
GB8608809D0 (en)	1986-05-14
EP0240609A3 (en)	1988-07-27
KR870010194A (ko)	1987-11-30
IE59523B1 (en)	1994-03-09
NZ218789A (en)	1990-09-26
PH23620A (en)	1989-09-11

Publication	Publication Date	Title
DE3683266D1 (de)	1992-02-13	Antibiotikum a 40926 mannosyl aglycon.
DE3682767D1 (de)	1992-01-16	Antibiotika-a40926-n-acylaminoglycuronyl-aglykone und antibiotika-a40926-aglykone.
DK312688A (da)	1988-06-09	Glykkopeptid-antibiotika
DK0406745T3 (da)	1995-02-27	Antibiotiske GE 2270 faktorer A1, A2, A3 og H
ATE121459T1 (de)	1995-05-15	Antibiotika ge 2270 faktoren b1, b2, c1, d1, d2, e und t.
ES2112517T3 (es)	1998-04-01	Antibioticos ge 37468 a, b y c.
AU6725387A (en)	1988-06-16	Drugs for the treatment and cure of all infectious diseases caused by pathogenic virulent micro-organisms