NO875239L - Fremgangsmaate ved spalting av 1,4-dihydropyridinderivateri optisk aktive isomerer. - Google Patents

Fremgangsmaate ved spalting av 1,4-dihydropyridinderivateri optisk aktive isomerer.

Info

Publication number
NO875239L
NO875239L NO875239A NO875239A NO875239L NO 875239 L NO875239 L NO 875239L NO 875239 A NO875239 A NO 875239A NO 875239 A NO875239 A NO 875239A NO 875239 L NO875239 L NO 875239L
Authority
NO
Norway
Prior art keywords
dihydropyridine
lower alkyl
dimethyl
aryl
carboxy
Prior art date
Application number
NO875239A
Other languages
English (en)
Norwegian (no)
Other versions
NO875239D0 (no
Inventor
Gilles Genain
Original Assignee
Syntex Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Lab filed Critical Syntex Lab
Publication of NO875239D0 publication Critical patent/NO875239D0/no
Publication of NO875239L publication Critical patent/NO875239L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO875239A 1986-12-22 1987-12-15 Fremgangsmaate ved spalting av 1,4-dihydropyridinderivateri optisk aktive isomerer. NO875239L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/945,760 US4920225A (en) 1986-12-22 1986-12-22 Resolution of 1,4-dihydropyridine derivatives

Publications (2)

Publication Number Publication Date
NO875239D0 NO875239D0 (no) 1987-12-15
NO875239L true NO875239L (no) 1988-06-23

Family

ID=25483522

Family Applications (1)

Application Number Title Priority Date Filing Date
NO875239A NO875239L (no) 1986-12-22 1987-12-15 Fremgangsmaate ved spalting av 1,4-dihydropyridinderivateri optisk aktive isomerer.

Country Status (13)

Country Link
US (1) US4920225A (fr)
EP (1) EP0273349A3 (fr)
JP (1) JPS63185960A (fr)
KR (1) KR880007469A (fr)
AU (1) AU8284887A (fr)
DK (1) DK674287A (fr)
FI (1) FI875623A7 (fr)
GB (1) GB2200631A (fr)
HU (1) HUT45499A (fr)
IE (1) IE873469L (fr)
IL (1) IL84894A0 (fr)
NO (1) NO875239L (fr)
ZA (1) ZA879579B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737340A1 (de) * 1987-11-04 1989-05-24 Bayer Ag Neue fluormethoxyphenyl-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
GB8804630D0 (en) * 1988-02-27 1988-03-30 Pfizer Ltd Preparation of r-& s-amlodipine
IT1230752B (it) * 1989-02-17 1991-10-29 Boehringer Biochemia Srl Processo per la preparazione di 1,4 diidropiridine polisostituite in forma enantiomericamente pura.
CA2016707A1 (fr) * 1989-05-15 1990-11-15 Graham A. Showell Procede de separation des 1-azabicyclo[2.2.1]heptane-3-carboxylates
JPH03141257A (ja) * 1989-10-26 1991-06-17 Green Cross Corp:The ジヒドロピリジン誘導体
US5100892A (en) * 1990-11-13 1992-03-31 Glaxo Inc. Dihydropyridine vasodilator agents
US5135936A (en) * 1991-03-05 1992-08-04 Marion Merrell Dow Inc. Isomers of 1-azabicyclo[2.2.2]oct-3-yl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinediacarboxylic and their use as calcium antagonists
US5210398A (en) * 1991-06-14 1993-05-11 Symbol Technologies, Inc. Optical scanner with extended depth of focus
FR2719585B1 (fr) * 1994-05-05 1996-08-02 Lafon Labor Procédé d'obtention de 1,4-dihydropyridines optiquement pures.
AU5568300A (en) 1999-06-23 2001-01-09 Ajinomoto Co., Inc. Novel dihydropyridine derivative
US20040106665A1 (en) * 2000-10-13 2004-06-03 Kress Thomas Joseph Resolution process for preparation of substantially pure (r) and (s) enantiomers of 2-(4-nitroimidazolyl)-4-methodxyphenylpropionic acid and salts thereof
ATE407925T1 (de) 2003-11-03 2008-09-15 Myogen Inc 1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungen
JP2007510728A (ja) * 2003-11-03 2007-04-26 ミオゲン インコーポレイティッド 心血管疾患を治療するための１，４−ジヒドロピリジン化合物、薬学的組成物、および方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4370334A (en) * 1975-07-02 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydro-pyridine derivatives and methods of using same
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
SE442298B (sv) * 1978-06-30 1985-12-16 Haessle Ab 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboxylsyra-3-metylester-5-etylester i optisk aktiv form
DE2935451A1 (de) * 1979-09-01 1981-03-19 Bayer Ag, 5090 Leverkusen Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel
CS228917B2 (en) * 1981-03-14 1984-05-14 Pfizer Method of preparing substituted derivatives of 1,4-dihydropyridine
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
JPS58208271A (ja) * 1982-04-30 1983-12-03 Kyowa Hakko Kogyo Co Ltd １，４−ジヒドロピリジン誘導体
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
DE3247118A1 (de) * 1982-12-20 1984-06-20 Cassella Ag, 6000 Frankfurt Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPS59161392A (ja) * 1983-03-04 1984-09-12 Nippon Shinyaku Co Ltd ジヒドロピリジン誘導体及びその製法
CA1339372C (fr) * 1983-09-26 1997-08-26 Nissan Chemical Industries Ltd. Ester cyclique d'acide dihydropyridine-5-phosphonique
GB8412208D0 (en) * 1984-05-12 1984-06-20 Pfizer Ltd Quinolone inotropic agents
DE3423105A1 (de) * 1984-06-22 1986-01-02 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung optisch aktiver 1,4-dihydropyridine
US4595690A (en) * 1985-02-11 1986-06-17 Syntex (U.S.A.) Inc. Antihypertensive dihydropyridine derivatives
IL77843A (en) * 1985-02-11 1989-07-31 Syntex Inc Dihydropyridine derivatives,process and novel intermediates for their preparation and pharmaceutical compositions containing them
US4761420A (en) * 1986-06-13 1988-08-02 Laboratoires Syntex S.A. Antihypertensive dihydropyridine derivatives

Also Published As

Publication number Publication date
IL84894A0 (en) 1988-06-30
FI875623A0 (fi) 1987-12-21
JPS63185960A (ja) 1988-08-01
KR880007469A (ko) 1988-08-27
EP0273349A3 (fr) 1990-02-14
IE873469L (en) 1988-06-22
DK674287D0 (da) 1987-12-21
AU8284887A (en) 1988-06-23
NO875239D0 (no) 1987-12-15
GB2200631A (en) 1988-08-10
US4920225A (en) 1990-04-24
EP0273349A2 (fr) 1988-07-06
HUT45499A (en) 1988-07-28
GB8729735D0 (en) 1988-02-03
DK674287A (da) 1988-06-23
ZA879579B (en) 1989-08-30
FI875623A7 (fi) 1988-06-23

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