NO902921L - Antibiotisk middel. - Google Patents

Antibiotisk middel.

Info

Publication number: NO902921L
Authority: NO; Norway
Prior art keywords: antibiotic agent; cultivation; isolation; production; activity against
Prior art date: 1989-06-30

Application number

NO90902921A

Other languages

English (en)

Other versions

NO178343B (no

NO902921D0 (no

NO178343C (no

Inventor

Robert E Schwartz

Raymond F White

Jerrold M Liesch

Otto D Hensens

Henry Joshua

Dennis M Schmatz

Robert A Giacobbe

Jan S Tkacz

Prakash S Masurekar

Louis Kaplan

Margaret S Sosa

Jimmy M Fountoulakis

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-30

Filing date

1990-06-29

Publication date

1991-01-02

1990-03-12 Priority claimed from US07/492,026 external-priority patent/US5021341A/en

1990-06-29 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1990-06-29 Publication of NO902921D0 publication Critical patent/NO902921D0/no

1991-01-02 Publication of NO902921L publication Critical patent/NO902921L/no

1995-11-27 Publication of NO178343B publication Critical patent/NO178343B/no

1996-03-06 Publication of NO178343C publication Critical patent/NO178343C/no

Links

239000003242 anti bacterial agent Substances 0.000 title abstract 2
229940088710 antibiotic agent Drugs 0.000 title abstract 2
108010028921 Lipopeptides Proteins 0.000 abstract 1
241000144175 Lophium arboricola Species 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
244000052637 human pathogen Species 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1
231100001225 mammalian toxicity Toxicity 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Compounds Of Unknown Constitution (AREA)

NO902921A 1989-06-30 1990-06-29 Fremgansmåte for fremstilling av terapeutisk aktiv 1-[4,5-dihydroksy-N2-(10,12-dimethyl-1-oxotetradecyl)-ornithinÅ-5-(3-hydroxyglutamin)-6-[3-hydroxyprolinÅechinocandin B NO178343C (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US37441689A	1989-06-30	1989-06-30
US49202590A	1990-03-12	1990-03-12
US49202490A	1990-03-12	1990-03-12
US07/492,026 US5021341A (en)	1990-03-12	1990-03-12	Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol

Publications (4)

Publication Number	Publication Date
NO902921D0 NO902921D0 (no)	1990-06-29
NO902921L true NO902921L (no)	1991-01-02
NO178343B NO178343B (no)	1995-11-27
NO178343C NO178343C (no)	1996-03-06

Family

ID=27503114

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO902921A NO178343C (no)	1989-06-30	1990-06-29	Fremgansmåte for fremstilling av terapeutisk aktiv 1-[4,5-dihydroksy-N2-(10,12-dimethyl-1-oxotetradecyl)-ornithinÅ-5-(3-hydroxyglutamin)-6-[3-hydroxyprolinÅechinocandin B

Country Status (16)

Country	Link
EP (1)	EP0405997B1 (no)
JP (1)	JPH0764873B2 (no)
KR (1)	KR0145693B1 (no)
AT (1)	ATE109160T1 (no)
AU (1)	AU639698B2 (no)
CA (1)	CA2020062C (no)
CY (1)	CY1962A (no)
DE (1)	DE69011006T2 (no)
DK (1)	DK0405997T3 (no)
ES (1)	ES2057413T3 (no)
FI (1)	FI93647C (no)
HK (1)	HK209496A (no)
IL (1)	IL94862A (no)
NO (1)	NO178343C (no)
NZ (1)	NZ234225A (no)
PT (1)	PT94555B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2037957A1 (en) *	1990-03-12	1991-09-13	Merck & Co., Inc.	N-acylated cyclohexapeptide compounds
US5310873A (en) *	1990-03-12	1994-05-10	Merck & Co., Inc.	Cyclohexapeptide compound
US5330973A (en)	1990-03-19	1994-07-19	Merck & Co., Inc.	Lipopeptide derivatives
JPH06502536A (ja) *	1990-10-09	1994-03-24	メルク　エンド　カンパニー　インコーポレーテッド	有機化合物の新規生物学的リン酸化方法
US5219985A (en) *	1990-10-31	1993-06-15	Merck & Co., Inc.	Antifungal agent
US5229363A (en) *	1991-02-19	1993-07-20	Merck & Co., Inc.	Cyclic hexapeptide compounds
US5369093A (en) *	1991-03-15	1994-11-29	Merck & Co., Inc.	Lipopeptide derivatives
US5336756A (en) *	1991-05-01	1994-08-09	Merck & Co., Inc.	Process for crystalline cyclic lipopeptides
US6030944A (en) *	1991-10-01	2000-02-29	Merck & Co., Inc.	Cyclohexapeptidyl bisamine compounds
US5348940A (en) *	1991-10-01	1994-09-20	Merck & Co., Inc.	Cyclohexapeptidyl hydroxypropionitrile compounds
EP0539088B1 (en) *	1991-10-17	1996-07-17	Merck & Co. Inc.	Echinocandin b derivative
US5914313A (en) *	1991-10-17	1999-06-22	Merck & Co., Inc.	1- 4-hydroxy-5-aminoethyloxy-N2 -(10,12-dimethyl-1-oxotetradecyl)ornithine!-5-(3-hydroxyglutamine)-6-(3-hydroxyproline)echinocandin B, other aminoalkyl derivatives and salts thereof
US5378804A (en) *	1993-03-16	1995-01-03	Merck & Co., Inc.	Aza cyclohexapeptide compounds
CA2161149A1 (en) *	1993-05-04	1994-11-10	James M. Balkovec	Cyclohexapeptidyl aminoalkyl ethers
EP1646370A1 (en) *	2003-07-11	2006-04-19	Glaxo Group Limited	Pharmaceutical formulations
CN102618604B (zh) *	2011-01-31	2014-09-03	上海天伟生物制药有限公司	一种环脂肽化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1183127A (en) *	1979-12-13	1985-02-26	Manuel Debono	Process for the preparation of derivatives of cyclic peptide nuclei
CA1182812A (en) *	1979-12-13	1985-02-19	Bernard J. Abbott	Process for the preparation of derivatives of cyclic peptide nuclei
JPS57501266A (no) *	1980-08-15	1982-07-22
DE3886001T2 (de) *	1987-10-07	1994-05-26	Merck & Co Inc	Fungizides Fermentationsprodukt.

1990
- 1990-06-25 IL IL9486290A patent/IL94862A/en unknown
- 1990-06-25 NZ NZ234225A patent/NZ234225A/xx unknown
- 1990-06-28 AU AU57973/90A patent/AU639698B2/en not_active Expired
- 1990-06-28 CA CA002020062A patent/CA2020062C/en not_active Expired - Lifetime
- 1990-06-28 FI FI903280A patent/FI93647C/fi active IP Right Grant
- 1990-06-29 PT PT94555A patent/PT94555B/pt not_active IP Right Cessation
- 1990-06-29 DK DK90307124.9T patent/DK0405997T3/da active
- 1990-06-29 AT AT90307124T patent/ATE109160T1/de not_active IP Right Cessation
- 1990-06-29 JP JP2172568A patent/JPH0764873B2/ja not_active Expired - Lifetime
- 1990-06-29 EP EP90307124A patent/EP0405997B1/en not_active Expired - Lifetime
- 1990-06-29 ES ES90307124T patent/ES2057413T3/es not_active Expired - Lifetime
- 1990-06-29 KR KR1019900009708A patent/KR0145693B1/ko not_active Expired - Lifetime
- 1990-06-29 DE DE69011006T patent/DE69011006T2/de not_active Expired - Lifetime
- 1990-06-29 NO NO902921A patent/NO178343C/no not_active IP Right Cessation
1996
- 1996-11-21 HK HK209496A patent/HK209496A/en not_active IP Right Cessation
1997
- 1997-07-04 CY CY196297A patent/CY1962A/xx unknown

Also Published As

Publication number	Publication date
DE69011006T2 (de)	1995-01-26
EP0405997A1 (en)	1991-01-02
NO178343B (no)	1995-11-27
JPH03163096A (ja)	1991-07-15
PT94555B (pt)	1997-02-28
CA2020062C (en)	1997-01-14
IL94862A0 (en)	1991-04-15
NO902921D0 (no)	1990-06-29
HK209496A (en)	1996-11-29
ES2057413T3 (es)	1994-10-16
JPH0764873B2 (ja)	1995-07-12
DK0405997T3 (da)	1994-10-31
AU639698B2 (en)	1993-08-05
DE69011006D1 (de)	1994-09-01
FI903280A0 (fi)	1990-06-28
FI93647C (fi)	1995-05-10
EP0405997B1 (en)	1994-07-27
KR910001068A (ko)	1991-01-30
PT94555A (pt)	1991-05-22
FI93647B (fi)	1995-01-31
CA2020062A1 (en)	1990-12-31
ATE109160T1 (de)	1994-08-15
IL94862A (en)	1994-10-07
CY1962A (en)	1997-07-04
NZ234225A (en)	1993-09-27
KR0145693B1 (ko)	1998-08-01
NO178343C (no)	1996-03-06
AU5797390A (en)	1991-01-03

Legal Events

Date	Code	Title	Description
2010-07-19	MK1K	Patent expired

Publication	Publication Date	Title
DK0405997T3 (da)	1994-10-31	Antibiotisk middel
DE69024965D1 (de)	1996-02-29	Dehydrodidemnin b
DE69127353D1 (de)	1997-09-25	Biomaterial auf kollagenbasis und seine anwendungen
ES2151607T3 (es)	2001-01-01	Factor 12 de crecimiento y de diferenciacion.
FR2591485B1 (fr)	1989-07-28	Compositions stabilisees contenant l'activateur du plasminogene du tissu humain.
ATE71113T1 (de)	1992-01-15	Antibiotikum a 40926 mannosyl aglycon.
EP0311194A3 (en)	1990-07-04	Process for antifungal fermentation product and culture
ATE78490T1 (de)	1992-08-15	Glykopeptid-antibiotika.
ES2042868T3 (es)	1993-12-16	Un metodo de producir galidermina.
ES2061770T3 (es)	1994-12-16	Antibioticos tan-1057.
ES2064398T3 (es)	1995-02-01	Un nuevo antibiotico, mersacidina, un procedimiento para su preparacion y su utilizacion como medicamento.
DE69104022D1 (de)	1994-10-20	Antibiotisches zyklisches Hexapeptid.
ES2051712T3 (es)	1994-07-01	Procedimiento para producir las composiciones denominadas ll-e19020 alfa y ll-e19020 beta.
ATE112169T1 (de)	1994-10-15	Menschliche myeloperoxidase und therapeutische verwendung.
DK0487613T3 (da)	1996-11-25	Megakarycytopiesk faktor
SE8402619D0 (sv)	1984-05-15	Bbm-1675, a new antitumor antibiotic complex
SE8902124D0 (sv)	1989-06-13	Medel foer behandling aav herpesinfektioner
ATE4637T1 (de)	1983-09-15	Pentadecapeptid, verfahren zu seiner herstellung und immunisierendes mittel.
ES8502729A1 (es)	1985-01-16	"un procedimiento para producir el complejo antibiotico m 9226"
ES2093054T3 (es)	1996-12-16	Antibioticos ab-023 y procedimiento para su preparacion.
ES2070210T3 (es)	1995-06-01	Derivado del activador de plasminogeno de tejido.
SE8400450D0 (sv)	1984-01-30	Luzopeptin e?712
AR240063A1 (es)	1990-01-31	Procedimiento para la produccion del activador del plasminogeno del tejido humano mediante el cultivo de la cepa de celulas registrada como kym-sf ifo 50135.
ES2060957T3 (es)	1994-12-01	Antibiotico antitumoral bu-3285t.
ES2038588T3 (es)	1993-08-01	Procedimiento para la obtencion de nuevos semihidratos cristalinos del 3-metoxi-4-(4'-aminobencenosulfonamido)-1,2,5-tiadiazol.