NO904511L - Pyrimidiner. - Google Patents

Pyrimidiner.

Info

Publication number
NO904511L
NO904511L NO90904511A NO904511A NO904511L NO 904511 L NO904511 L NO 904511L NO 90904511 A NO90904511 A NO 90904511A NO 904511 A NO904511 A NO 904511A NO 904511 L NO904511 L NO 904511L
Authority
NO
Norway
Prior art keywords
pyrimidine
Prior art date
Application number
NO90904511A
Other languages
English (en)
Other versions
NO176758C (no
NO904511D0 (no
NO176758B (no
Inventor
Peter Herold
Peter Buehlmayer
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO904511D0 publication Critical patent/NO904511D0/no
Publication of NO904511L publication Critical patent/NO904511L/no
Publication of NO176758B publication Critical patent/NO176758B/no
Publication of NO176758C publication Critical patent/NO176758C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO904511A 1989-10-19 1990-10-18 Analogifremgangsmåte for fremstilling av terapeutiske anvendbare tetrazolyl-bifenylylmetyl-pyrimidiner NO176758C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH379989 1989-10-19

Publications (4)

Publication Number Publication Date
NO904511D0 NO904511D0 (no) 1990-10-18
NO904511L true NO904511L (no) 1991-04-22
NO176758B NO176758B (no) 1995-02-13
NO176758C NO176758C (no) 1995-05-24

Family

ID=4263704

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904511A NO176758C (no) 1989-10-19 1990-10-18 Analogifremgangsmåte for fremstilling av terapeutiske anvendbare tetrazolyl-bifenylylmetyl-pyrimidiner

Country Status (14)

Country Link
EP (1) EP0424317A3 (no)
JP (1) JPH03133964A (no)
KR (1) KR910007889A (no)
AU (1) AU638496B2 (no)
CA (1) CA2027839A1 (no)
FI (1) FI93957C (no)
HU (1) HUT55383A (no)
IE (1) IE903749A1 (no)
IL (1) IL96009A0 (no)
MX (1) MX22877A (no)
NO (1) NO176758C (no)
NZ (1) NZ235726A (no)
PT (1) PT95626A (no)
ZA (1) ZA908344B (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324729A (en) * 1990-03-30 1994-06-28 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
WO1991015209A1 (en) * 1990-03-30 1991-10-17 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
KR100196559B1 (ko) * 1990-06-19 1999-06-15 기따사또 이찌로 안지오텐신ii 길항작용을 함유하는 피리딘 유도체
IL99246A0 (en) * 1990-09-10 1992-07-15 Abbott Lab Angiotensin ii receptor antagonists and pharmaceutical compositions containing them
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
CA2053148A1 (en) * 1990-10-16 1992-04-17 Karnail Atwal Dihydropyrimidine derivatives
FR2672892B1 (fr) * 1991-02-20 1994-01-14 Synthelabo Derives de 4-pyrimidinones, leur preparation et leur application en therapeutique.
US5472967A (en) * 1991-02-20 1995-12-05 Synthelabo 4-pyrimidinone derivatives their preparation and their application in therapy
DE4110019C2 (de) * 1991-03-27 2000-04-13 Merck Patent Gmbh Imidazopyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
AU1625192A (en) * 1991-05-31 1992-12-03 Zeneca Limited Heterocyclic derivatives
IT1250749B (it) * 1991-08-02 1995-04-21 Luso Farmaco Inst Composti eterociclici ad attivita' a ii antagonista
US5234936A (en) * 1991-10-24 1993-08-10 American Home Products Corporation Pyrimidocycloalkanes as a ii antagonists
US5256781A (en) * 1991-10-24 1993-10-26 American Home Products Corporation Substituted quinazolines as angiotensin II antagonists
US5236925A (en) * 1991-10-24 1993-08-17 American Home Products Corporation Fused pyrimidines as angiotensin II antagonists
DE4221583A1 (de) 1991-11-12 1993-05-13 Bayer Ag Substituierte biphenylpyridone
GB9125842D0 (en) * 1991-12-04 1992-02-05 Ici Plc Heterocyclic derivatives
US5225408A (en) * 1991-12-20 1993-07-06 E. R. Squibb & Sons, Inc. Biphenyl oxadiazinone angiotensin II inhibitors
IL104756A0 (en) * 1992-02-17 1993-06-10 Ciba Geigy Ag Composition for the treatment of glaucoma
US5378704A (en) * 1992-04-15 1995-01-03 E. R. Squibb & Sons, Inc. Non-peptidic angiotensin-II-receptor-antagonists
US5236916A (en) * 1992-05-26 1993-08-17 E. R. Squibb & Sons, Inc. Oxadiazinone substituted indole and benzimidazole derivatives
TW348175B (en) * 1993-01-06 1998-12-21 Hoechst Ag Process for the preparation of biphenyl derivatives
US6518424B1 (en) 1998-11-12 2003-02-11 Elan Pharmaceuticals, Inc. Substituted pyrimidine compositions and methods of use
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
WO2006038719A1 (ja) * 2004-10-08 2006-04-13 Kotobuki Pharmaceutical Co., Ltd. ホスホン酸誘導体及び血中の高リン酸が関与する疾患の治療剤
AU2006235698B2 (en) * 2005-04-12 2012-03-29 Vicore Pharma Ab New tricyclic angiotensin II agonists
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
WO2011105099A1 (ja) * 2010-02-25 2011-09-01 興和株式会社 新規な４－アルコキシピリミジン構造を有する化合物及びこれを含有する医薬
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
WO2022057858A1 (zh) * 2020-09-17 2022-03-24 浙江海正药业股份有限公司 酰胺膦氧类衍生物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles

Also Published As

Publication number Publication date
MX22877A (es) 1993-12-01
NO176758C (no) 1995-05-24
FI93957B (fi) 1995-03-15
FI905124A0 (fi) 1990-10-17
FI93957C (fi) 1995-06-26
AU638496B2 (en) 1993-07-01
NZ235726A (en) 1993-09-27
AU6468090A (en) 1991-04-26
CA2027839A1 (en) 1991-04-20
NO904511D0 (no) 1990-10-18
HU906501D0 (en) 1991-04-29
NO176758B (no) 1995-02-13
IE903749A1 (en) 1991-04-24
KR910007889A (ko) 1991-05-30
PT95626A (pt) 1991-09-13
ZA908344B (en) 1991-06-26
HUT55383A (en) 1991-05-28
JPH03133964A (ja) 1991-06-07
EP0424317A2 (de) 1991-04-24
EP0424317A3 (en) 1991-09-25
IL96009A0 (en) 1991-07-18

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