NO952977L - Aminoduhydro-oksopurinyl-metoksypropandiolderivater - Google Patents

Aminoduhydro-oksopurinyl-metoksypropandiolderivater

Info

Publication number: NO952977L
Authority: NO; Norway
Prior art keywords: oksopurinyl; metoksypropandiolderivater; aminoduhydro; purin; propanediol
Prior art date: 1994-07-28

Application number

NO952977A

Other languages

English (en)

Other versions

NO952977D0 (no

NO312899B1 (no

Inventor

John J Nestor

Scott W Womble

Hans Maag

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-28

Filing date

1995-07-27

Publication date

1996-01-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23079211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO952977(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-07-27 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1995-07-27 Publication of NO952977D0 publication Critical patent/NO952977D0/no

1996-01-29 Publication of NO952977L publication Critical patent/NO952977L/no

2002-07-15 Publication of NO312899B1 publication Critical patent/NO312899B1/no

Links

238000010521 absorption reaction Methods 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)

NO19952977A 1994-07-28 1995-07-27 Aminodihydro-oksopurinyl-metoksypropandiolderivater NO312899B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US28189394A	1994-07-28	1994-07-28

Publications (3)

Publication Number	Publication Date
NO952977D0 NO952977D0 (no)	1995-07-27
NO952977L true NO952977L (no)	1996-01-29
NO312899B1 NO312899B1 (no)	2002-07-15

Family

ID=23079211

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO19952977A NO312899B1 (no)	1994-07-28	1995-07-27	Aminodihydro-oksopurinyl-metoksypropandiolderivater
NO2003001C NO2003001I2 (no)	1994-07-28	2003-01-10	Valganciklovir

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO2003001C NO2003001I2 (no)	1994-07-28	2003-01-10	Valganciklovir

Country Status (32)

Country	Link
EP (1)	EP0694547B1 (no)
JP (1)	JP3090305B2 (no)
KR (1)	KR100358626B1 (no)
CN (1)	CN1045089C (no)
AT (1)	ATE179173T1 (no)
AU (1)	AU697107B2 (no)
BR (1)	BR9503468A (no)
CA (1)	CA2154721C (no)
CO (1)	CO4410181A1 (no)
CY (2)	CY2180B1 (no)
CZ (1)	CZ290511B6 (no)
DE (3)	DE694547T1 (no)
DK (1)	DK0694547T3 (no)
ES (1)	ES2083348T3 (no)
FI (1)	FI112080B (no)
GR (2)	GR960300021T1 (no)
HU (1)	HU216867B (no)
IL (1)	IL114735A (no)
LU (1)	LU91136I2 (no)
MA (1)	MA23631A1 (no)
MY (1)	MY114393A (no)
NL (1)	NL300071I2 (no)
NO (2)	NO312899B1 (no)
NZ (1)	NZ272652A (no)
PE (1)	PE32296A1 (no)
PL (1)	PL180609B1 (no)
RU (1)	RU2133749C1 (no)
SA (1)	SA95160158B1 (no)
TR (1)	TR199500895A2 (no)
TW (1)	TW434242B (no)
UY (1)	UY24006A1 (no)
ZA (1)	ZA956228B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6458772B1 (en)	1909-10-07	2002-10-01	Medivir Ab	Prodrugs
AU1592897A (en) *	1996-01-26	1997-08-20	F. Hoffmann-La Roche Ag	Process for preparing purine derivatives
US5756736A (en) *	1996-01-26	1998-05-26	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5840890A (en) *	1996-01-26	1998-11-24	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
KR100491941B1 (ko) *	1996-01-26	2005-08-05	에프. 호프만-라 로슈 아게	푸린유도체의제조방법
US5700936A (en) *	1996-01-26	1997-12-23	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5869493A (en)	1996-02-16	1999-02-09	Medivir Ab	Acyclic nucleoside derivatives
US6703394B2 (en)	1996-02-16	2004-03-09	Medivir Ab	Acyclic nucleoside derivatives
US6184376B1 (en)	1997-02-10	2001-02-06	Mediver Ab	Synthesis of acyclic nucleoside derivatives
EP0971923B1 (en) *	1997-02-10	2002-11-06	Medivir Ab	Synthesis of acyclic nucleoside derivatives
AU728892B2 (en) *	1997-08-15	2001-01-18	Medivir Ab	Nucleosides analogues, such as antivirals including inhibitors of retroviral reverse transcriptase and the DNA polymerase of hepatitis B virus (HBV)
WO1999032490A1 (en) *	1997-12-19	1999-07-01	Bristol-Myers Squibb Company	Prodrugs of lobucavir and methods of use
WO1999051613A1 (en) *	1998-04-03	1999-10-14	Medivir Ab	Prodrugs of phosphorous-containing pharmaceuticals
JP2000256359A (ja) *	1999-03-11	2000-09-19	Japan Science & Technology Corp	面性キラリティーを有する分子群の高選択的不斉変換法
KR20030015655A (ko) *	2001-08-17	2003-02-25	한미약품공업 주식회사	항암제의 경구흡수율을 증가시키는 인단계 화합물의결정성 산부가염, 이의 제조방법 및 이를 함유하는 약학적조성물
DE60328675D1 (de) *	2002-04-23	2009-09-17	Aventis Pharma Inc	3-(substitutierte amino)-1h-indole-2-carbonsäureester und 3-(substitutierte amino)-benzoäbüthiophen-2-carbonsäureester verbindungen als inhibitoren der interleukin-4 genexpression
EP1552833B1 (en)	2002-10-16	2016-12-28	Takeda Pharmaceutical Company Limited	Process for producing an amorphous optically active isomer of lansoprazole
EA015145B1 (ru)	2003-01-14	2011-06-30	Джилид Сайэнс, Инк.	Фармацевтическая композиция и пероральная фармацевтическая дозированная форма (варианты), проявляющие активность в отношении вич-инфекций, лечебный набор и таблетка и способ лечения или предотвращения симптомов или эффектов вич-инфекции
CN1860120A (zh) *	2003-08-28	2006-11-08	兰贝克赛实验室有限公司	无定形盐酸缬更昔洛韦
EP1768668A2 (en)	2004-06-16	2007-04-04	Tap Pharmaceutical Products, Inc.	Multiple ppi dosage form
CN103223160B (zh) *	2004-07-19	2015-02-18	比奥孔有限公司	胰岛素-低聚物共轭物,制剂及其用途
TWI375560B (en)	2005-06-13	2012-11-01	Gilead Sciences Inc	Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh)	2005-06-13	2015-02-01	Bristol Myers Squibb & Gilead Sciences Llc	單一式藥學劑量型
ZA200702234B (en) *	2006-03-21	2008-07-30	Cipla Ltd	Preparation of ester of purine derivatives
CN102014638A (zh)	2007-10-12	2011-04-13	武田制药北美公司	与食物摄入无关的治疗胃肠病症的方法
CN103562207B (zh) *	2011-05-31	2016-08-17	法尔玛赞公司	用于制备缬更昔洛韦的2-氨基-9-((2-苯基-1，3-二噁烷-5-基氧基)甲基)-1h-嘌呤-6(9h)-酮化合物的制备方法
KR102312533B1 (ko)	2021-02-24	2021-10-15	주식회사 이웅	자동 스패너

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8202626A (nl) *	1982-06-29	1984-01-16	Stichting Rega V Z W	Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
US4897479A (en) *	1983-09-30	1990-01-30	Merck & Co., Inc.	Arylsulfonyloxy purine intermediates
IE842642L (en) *	1983-10-31	1985-04-30	Harvard College	Purine Derivatives
CA1330797C (en) *	1984-12-12	1994-07-19	David J. Morgans, Jr.	Alkoxy methyl ether and alkoxy methyl ester derivatives
AP55A (en) *	1987-08-15	1989-09-26	The Wellcome Foundation Ltd	Therapeutic Acyclic Nucleosides
CA2005815C (en) *	1988-12-19	1999-08-03	Wellcome Foundation Limited (The)	Antiviral acyclic nucleoside derivatives

1995
- 1995-07-10 PE PE1995273436A patent/PE32296A1/es not_active IP Right Cessation
- 1995-07-19 AT AT95111319T patent/ATE179173T1/de active
- 1995-07-19 DE DE0694547T patent/DE694547T1/de active Pending
- 1995-07-19 DE DE69509173T patent/DE69509173T2/de not_active Expired - Lifetime
- 1995-07-19 DK DK95111319T patent/DK0694547T3/da active
- 1995-07-19 ES ES95111319T patent/ES2083348T3/es not_active Expired - Lifetime
- 1995-07-19 DE DE2002199032 patent/DE10299032I2/de active Active
- 1995-07-19 EP EP95111319A patent/EP0694547B1/en not_active Expired - Lifetime
- 1995-07-21 TR TR95/00895A patent/TR199500895A2/xx unknown
- 1995-07-26 HU HU9502238A patent/HU216867B/hu unknown
- 1995-07-26 IL IL114735A patent/IL114735A/en not_active IP Right Cessation
- 1995-07-26 MA MA23971A patent/MA23631A1/fr unknown
- 1995-07-26 NZ NZ272652A patent/NZ272652A/en not_active IP Right Cessation
- 1995-07-26 ZA ZA956228A patent/ZA956228B/xx unknown
- 1995-07-26 AU AU27195/95A patent/AU697107B2/en not_active Expired
- 1995-07-26 CA CA002154721A patent/CA2154721C/en not_active Expired - Lifetime
- 1995-07-27 JP JP07190953A patent/JP3090305B2/ja not_active Expired - Lifetime
- 1995-07-27 RU RU95113148A patent/RU2133749C1/ru active
- 1995-07-27 BR BR9503468A patent/BR9503468A/pt active Search and Examination
- 1995-07-27 CZ CZ19951939A patent/CZ290511B6/cs not_active IP Right Cessation
- 1995-07-27 TW TW084107779A patent/TW434242B/zh not_active IP Right Cessation
- 1995-07-27 NO NO19952977A patent/NO312899B1/no not_active IP Right Cessation
- 1995-07-27 CO CO95033418A patent/CO4410181A1/es unknown
- 1995-07-27 PL PL95309812A patent/PL180609B1/pl unknown
- 1995-07-27 MY MYPI95002156A patent/MY114393A/en unknown
- 1995-07-27 FI FI953592A patent/FI112080B/fi active Protection Beyond IP Right Term
- 1995-07-27 KR KR1019950022600A patent/KR100358626B1/ko not_active Expired - Lifetime
- 1995-07-27 CN CN95109671A patent/CN1045089C/zh not_active Expired - Lifetime
- 1995-07-27 UY UY24006A patent/UY24006A1/es not_active IP Right Cessation
- 1995-08-14 SA SA95160158A patent/SA95160158B1/ar unknown
1996
- 1996-04-30 GR GR960300021T patent/GR960300021T1/el unknown
1999
- 1999-07-02 GR GR990401760T patent/GR3030678T3/el unknown
2000
- 2000-08-10 CY CY0000039A patent/CY2180B1/xx unknown
2001
- 2001-11-23 NL NL300071C patent/NL300071I2/nl unknown
2003
- 2003-01-10 NO NO2003001C patent/NO2003001I2/no unknown
- 2003-05-21 LU LU91136C patent/LU91136I2/fr unknown
2004
- 2004-10-20 CY CY200400003C patent/CY2004003I1/el unknown

Also Published As

Publication number	Publication date
TR199500895A2 (tr)	1996-06-21
PL309812A1 (en)	1996-02-05
ZA956228B (en)	1996-02-22
UY24006A1 (es)	2001-07-31
GR960300021T1 (en)	1996-04-30
KR960004345A (ko)	1996-02-23
DE10299032I2 (de)	2006-06-14
FI953592A0 (fi)	1995-07-27
DE69509173T2 (de)	1999-10-21
MA23631A1 (fr)	1996-04-01
JP3090305B2 (ja)	2000-09-18
KR100358626B1 (ko)	2003-01-14
ATE179173T1 (de)	1999-05-15
TW434242B (en)	2001-05-16
CN1045089C (zh)	1999-09-15
EP0694547A2 (en)	1996-01-31
IL114735A (en)	1998-06-15
IL114735A0 (en)	1995-11-27
FI953592L (fi)	1996-01-29
CY2180B1 (en)	2002-08-23
NL300071I1 (nl)	2002-02-01
CO4410181A1 (es)	1997-01-09
NO2003001I2 (no)	2007-06-11
SA95160158B1 (ar)	2006-05-20
PE32296A1 (es)	1996-08-07
AU2719595A (en)	1996-02-08
CY2004003I2 (el)	2009-11-04
LU91136I2 (fr)	2005-07-06
RU2133749C1 (ru)	1999-07-27
NO952977D0 (no)	1995-07-27
MY114393A (en)	2002-10-31
PL180609B1 (pl)	2001-03-30
DK0694547T3 (da)	2000-01-03
HU216867B (hu)	1999-09-28
RU95113148A (ru)	1997-06-27
CY2004003I1 (el)	2009-11-04
ES2083348T3 (es)	1999-08-01
EP0694547A3 (en)	1996-06-05
DE694547T1 (de)	1996-10-24
DE69509173D1 (de)	1999-05-27
ES2083348T1 (es)	1996-04-16
HK1012339A1 (en)	1999-07-30
NZ272652A (en)	1996-12-20
CA2154721A1 (en)	1996-01-29
CN1122804A (zh)	1996-05-22
HUT73246A (en)	1996-07-29
FI112080B (fi)	2003-10-31
GR3030678T3 (en)	1999-11-30
CZ290511B6 (cs)	2002-08-14
CZ193995A3 (en)	1996-02-14
JPH0841061A (ja)	1996-02-13
AU697107B2 (en)	1998-09-24
DE10299032I1 (de)	2003-01-23
NL300071I2 (nl)	2002-03-01
HU9502238D0 (en)	1995-09-28
EP0694547B1 (en)	1999-04-21
NO312899B1 (no)	2002-07-15
CA2154721C (en)	2001-01-02
BR9503468A (pt)	1996-02-27

Legal Events

Date	Code	Title	Description
2003-01-27	SPCF	Filing of supplementary protection certificate	Free format text: PRODUCT NAME: VALGANCIKLOVIR; NAT. REG. NO/DATE: NO , 01-11894 20020411; FIRST REG. NO/DATE: NL , RVG 25992 20010920 Spc suppl protection certif: 2003001 Filing date: 20030110
2007-06-11	SPCG	Granted supplementary protection certificate	Free format text: PRODUCT NAME: VALGANCIKLOVIR; NAT. REG. NO/DATE: NO , 01-11894 20020411; FIRST REG. NO/DATE: NL , RVG 25992 20010920 Spc suppl protection certif: 2003001 Filing date: 20030110 Extension date: 20160920
2015-08-10	MK1K	Patent expired
2016-10-17	SPCX	Expiry of an spc	Spc suppl protection certif: 2003001

Publication	Publication Date	Title
NO952977D0 (no)	1995-07-27	Aminoduhydro-kosopurinyl-metoksypropandiolderivater
FI914928A0 (fi)	1991-10-18	Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
FI932831A0 (fi)	1993-06-18	Ett foerfarande foer framstaellning av en syntetisk ledarsekvens
MX9204190A (es)	1993-01-01	Derivdos de 2-(4-hidroxipiperidino)-1-alcanol como agentes antiisquemicos.
PT97259A (pt)	1992-01-31	Processo para a estabilizacao de isotiazolonas com fenoxialcanois
DK0566175T3 (da)	1998-01-26	3,4-diaryl-(5H)-furan-2-on-baserede forbindelser med fungicid aktivitet
DK0625520T3 (da)	2000-01-31	Thiazolotriazol- og thiazolodiazolderivater med fungicid aktivitet
FI916018A7 (fi)	1992-06-21	1,3-dioksolaanijohdannaisia kolesterolia alentavina aineina
ES2093051T3 (es)	1996-12-16	Purinil- y pirimidil-tetrahidrofuranos.
NO903796D0 (no)	1990-08-30	Fremgangsmaate for fremstilling av optisk aktive epoksyder.
FI920470A0 (fi)	1992-02-04	Foerfarande foer lokalisering med laser.
ECSP951495A (es)	1996-12-13	Derivado de 2-(2-amino-1,6- dihidro-6-oxo- purin-9-il) metoxi-1,3- propan-diol
IT232873Y1 (it)	2000-01-21	suola ad assorbimento d'impatto.