NO955261L - N-substituerte azaheterosykliske karboksylsyrer og estere derav - Google Patents

N-substituerte azaheterosykliske karboksylsyrer og estere derav

Info

Publication number
NO955261L
NO955261L NO955261A NO955261A NO955261L NO 955261 L NO955261 L NO 955261L NO 955261 A NO955261 A NO 955261A NO 955261 A NO955261 A NO 955261A NO 955261 L NO955261 L NO 955261L
Authority
NO
Norway
Prior art keywords
esters
carboxylic acids
compounds
saturated
formula
Prior art date
Application number
NO955261A
Other languages
English (en)
Other versions
NO955261D0 (no
Inventor
Knud Erik Andersen
Jesper Lau
Per Olaf Soerensen
Hans Petersen
Behrend Friedrich Lundt
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO955261D0 publication Critical patent/NO955261D0/no
Publication of NO955261L publication Critical patent/NO955261L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Terapeutisk aktive, azahetero-sykliske forbindelser med formel (I). fremgangsmåte for fremstilling av disse og farmasøytiske preparater som omfatter forbindelsene. De nye forbindelsene kan anvendes ved behandling av en sentralnervesystemlidelse relatert til GBA-opptaket. I formel (I) er A en mettet eller umettet karbosyklisk 5-eller 6-ring som eventuelt er substituert med fenyl, benzyliden, Cj^-alkyl substituert med fenyl eller C.-alkenyl substituert med fenyl, hvor fenyl eller benzyliden eventuelt er substituert med halogen, C,.-alkyl, C-alkoksy eller. trifluormetyl, og hvor den mettede eller umettede karbosykliske 5- eller 6-ring eventuelt kan være kondensert med en benzoring.
NO955261A 1993-06-23 1995-12-22 N-substituerte azaheterosykliske karboksylsyrer og estere derav NO955261L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93744A DK74493D0 (da) 1993-06-23 1993-06-23 Novel heterocyclic chemistry
PCT/DK1994/000251 WO1995000484A1 (en) 1993-06-23 1994-06-22 N-substituted azaheterocyclic carboxylic acids and esters thereof

Publications (2)

Publication Number Publication Date
NO955261D0 NO955261D0 (no) 1995-12-22
NO955261L true NO955261L (no) 1996-02-22

Family

ID=8097043

Family Applications (1)

Application Number Title Priority Date Filing Date
NO955261A NO955261L (no) 1993-06-23 1995-12-22 N-substituerte azaheterosykliske karboksylsyrer og estere derav

Country Status (16)

Country Link
US (1) US5639766A (no)
EP (1) EP0707568A1 (no)
JP (1) JPH08511781A (no)
CN (1) CN1128991A (no)
AU (1) AU6996094A (no)
BG (1) BG100245A (no)
CA (1) CA2165948A1 (no)
CZ (1) CZ335595A3 (no)
DK (1) DK74493D0 (no)
FI (1) FI956175A7 (no)
HU (1) HUT73242A (no)
IL (1) IL110076A0 (no)
NO (1) NO955261L (no)
SK (1) SK162395A3 (no)
WO (1) WO1995000484A1 (no)
ZA (1) ZA944468B (no)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK270488D0 (da) * 1988-05-18 1988-05-18 Novo Industri As Hidtil ukendte o-substituerede ketoximer
DK93791D0 (da) * 1991-05-17 1991-05-17 Novo Nordisk As Nye heterocykliske carboxylsyrer

Also Published As

Publication number Publication date
ZA944468B (en) 1995-12-22
AU6996094A (en) 1995-01-17
WO1995000484A1 (en) 1995-01-05
JPH08511781A (ja) 1996-12-10
NO955261D0 (no) 1995-12-22
EP0707568A1 (en) 1996-04-24
HUT73242A (en) 1996-07-29
IL110076A0 (en) 1994-10-07
DK74493D0 (da) 1993-06-23
CA2165948A1 (en) 1995-01-05
HU9503754D0 (en) 1996-02-28
US5639766A (en) 1997-06-17
FI956175L (fi) 1996-02-21
CN1128991A (zh) 1996-08-14
FI956175A0 (fi) 1995-12-21
SK162395A3 (en) 1996-09-04
BG100245A (bg) 1996-05-31
FI956175A7 (fi) 1996-02-21
CZ335595A3 (en) 1996-07-17

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