NO955262L - N-substituerte azaheterosykliske karboksylsyrer og estere derav - Google Patents

N-substituerte azaheterosykliske karboksylsyrer og estere derav

Info

Publication number
NO955262L
NO955262L NO955262A NO955262A NO955262L NO 955262 L NO955262 L NO 955262L NO 955262 A NO955262 A NO 955262A NO 955262 A NO955262 A NO 955262A NO 955262 L NO955262 L NO 955262L
Authority
NO
Norway
Prior art keywords
phenyl
substituted
esters
carboxylic acids
compounds
Prior art date
Application number
NO955262A
Other languages
English (en)
Other versions
NO955262D0 (no
Inventor
Per Olaf Soerensen
Jesper Lau
Knud Erik Andersen
Hans Petersen
Behrend Friedrich Lundt
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO955262D0 publication Critical patent/NO955262D0/no
Publication of NO955262L publication Critical patent/NO955262L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Terapeutisk aktive, azahetero- sykliske forbindelser med formel (I) R A-0-(CH2)n- N r\cox O*1 fremgangsmåte for fremstilling av disse og farmasøytiske preparater som omfatter forbindelsene. De nye forbin- delsene kan anvendes ved behandling av en sentralnervesystemlidelse relatert til GABA-opptaket. I formelen er A en mettet eller umettet karbosyklisk 5- eller 6-ring som eventuelt er substi- tuert med fenyl, benzyliden, C^-alkyl substituert med fenyl eller C2_«-alkenyl substituert med fenyl, hvor fenyl eller benzyliden eventuelt er substituert med halogen, C^-alkyl, Cj.4-alkoksy eller trifluormetyl, og hvor den mettede eller umettede karbosykliske 5- eller 6-ring eventuelt kan være kondensert med en benzenring.
NO955262A 1993-06-23 1995-12-22 N-substituerte azaheterosykliske karboksylsyrer og estere derav NO955262L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93745A DK74593D0 (da) 1993-06-23 1993-06-23 Novel heterocyclic chemistry
PCT/DK1994/000252 WO1995000485A1 (en) 1993-06-23 1994-06-22 N-substituted azaheterocyclic carboxylic acids and esters thereof

Publications (2)

Publication Number Publication Date
NO955262D0 NO955262D0 (no) 1995-12-22
NO955262L true NO955262L (no) 1996-02-22

Family

ID=8097055

Family Applications (1)

Application Number Title Priority Date Filing Date
NO955262A NO955262L (no) 1993-06-23 1995-12-22 N-substituerte azaheterosykliske karboksylsyrer og estere derav

Country Status (16)

Country Link
US (1) US5635518A (no)
EP (1) EP0705247A1 (no)
JP (1) JPH08511782A (no)
CN (1) CN1128988A (no)
AU (1) AU6996194A (no)
BG (1) BG100249A (no)
CA (1) CA2165947A1 (no)
CZ (1) CZ335095A3 (no)
DK (1) DK74593D0 (no)
FI (1) FI956176L (no)
HU (1) HUT73243A (no)
IL (1) IL110077A0 (no)
NO (1) NO955262L (no)
SK (1) SK162295A3 (no)
WO (1) WO1995000485A1 (no)
ZA (1) ZA944469B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050044396A (ko) * 2001-11-12 2005-05-12 노파르티스 아게 정동 및 주의력 장애 및 신경병성 통증 치료용 의약제조에 사용하기 위한 모노히드록시카르바마제핀
CN1382441A (zh) * 2002-05-21 2002-12-04 中国科学院上海生命科学研究院 γ－氨基丁酸转运蛋白抑制剂在制备镇痛药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI864246A7 (fi) * 1985-11-08 1987-05-09 Warner Lambert Co N-substituerade 3-piperidin- eller 3-pyridinkarboxylsyror samt deras derivat.
EP0252876A1 (de) * 1986-06-26 1988-01-13 Ciba-Geigy Ag Hydrierte 1-Phenoxyalkylpyridin-3-carbonsäureverbindungen

Also Published As

Publication number Publication date
EP0705247A1 (en) 1996-04-10
CZ335095A3 (en) 1996-08-14
SK162295A3 (en) 1996-09-04
NO955262D0 (no) 1995-12-22
FI956176A7 (fi) 1996-02-21
WO1995000485A1 (en) 1995-01-05
CA2165947A1 (en) 1995-01-05
ZA944469B (en) 1995-12-22
DK74593D0 (da) 1993-06-23
HUT73243A (en) 1996-07-29
FI956176L (fi) 1996-02-21
CN1128988A (zh) 1996-08-14
BG100249A (en) 1996-07-31
US5635518A (en) 1997-06-03
HU9503752D0 (en) 1996-02-28
AU6996194A (en) 1995-01-17
IL110077A0 (en) 1994-10-07
FI956176A0 (fi) 1995-12-21
JPH08511782A (ja) 1996-12-10

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