NO972460D0 - Nye substituerte DTPA-derivater, deres metallkomplekser, farmasöytiske midler inneholdende metallkompleksene samt deres anvendelse ved diagnostikk og terapi - Google Patents
Nye substituerte DTPA-derivater, deres metallkomplekser, farmasöytiske midler inneholdende metallkompleksene samt deres anvendelse ved diagnostikk og terapiInfo
- Publication number
- NO972460D0 NO972460D0 NO972460A NO972460A NO972460D0 NO 972460 D0 NO972460 D0 NO 972460D0 NO 972460 A NO972460 A NO 972460A NO 972460 A NO972460 A NO 972460A NO 972460 D0 NO972460 D0 NO 972460D0
- Authority
- NO
- Norway
- Prior art keywords
- metal complexes
- diagnostics
- therapy
- new substituted
- pharmaceuticals containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Radiology & Medical Imaging (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pathology (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Colloid Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35108694A | 1994-11-30 | 1994-11-30 | |
| US38740895A | 1995-02-13 | 1995-02-13 | |
| PCT/EP1995/004548 WO1996016928A1 (de) | 1994-11-30 | 1995-11-20 | Neuartig substituierte dtpa-derivate, deren metallkomplexe, diese komplexe enthaltende pharmazeutische mittel und deren verwendung in der diagnostik und therapie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO972460D0 true NO972460D0 (no) | 1997-05-29 |
| NO972460L NO972460L (no) | 1997-05-29 |
Family
ID=26996938
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO972459A NO972459L (no) | 1994-11-30 | 1997-05-29 | Nye flersubst DTPA-derivater og deres metallkomplekser, farmasöytiske preparater inneh slike komplekser, deres anv ved diagnostikk og terapi, fremg for fremst av de kompleksdannende midler og komplekser, samt fremg for frems av de farmasöytiske |
| NO972460A NO972460L (no) | 1994-11-30 | 1997-05-29 | Nye substituerte DTPA-derivater, deres metallkomplekser, farmasöytiske midler inneholdende metallkompleksene samt deres anvendelse ved diagnostikk og terapi |
| NO972457A NO972457L (no) | 1994-11-30 | 1997-05-29 | Anvendelse av metallkomplekser som lever- og galleröntgendiagnostika i datatomografien |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO972459A NO972459L (no) | 1994-11-30 | 1997-05-29 | Nye flersubst DTPA-derivater og deres metallkomplekser, farmasöytiske preparater inneh slike komplekser, deres anv ved diagnostikk og terapi, fremg for fremst av de kompleksdannende midler og komplekser, samt fremg for frems av de farmasöytiske |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO972457A NO972457L (no) | 1994-11-30 | 1997-05-29 | Anvendelse av metallkomplekser som lever- og galleröntgendiagnostika i datatomografien |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US5672335A (no) |
| EP (3) | EP0794938A1 (no) |
| JP (3) | JPH10511934A (no) |
| CN (1) | CN1167444A (no) |
| AU (3) | AU4254696A (no) |
| CA (3) | CA2206576A1 (no) |
| CZ (1) | CZ166897A3 (no) |
| FI (3) | FI972286A0 (no) |
| HU (1) | HUT77284A (no) |
| IL (3) | IL116208A0 (no) |
| MX (1) | MX9703880A (no) |
| NO (3) | NO972459L (no) |
| PL (1) | PL320462A1 (no) |
| SK (1) | SK68997A3 (no) |
| WO (3) | WO1996016677A2 (no) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9501560D0 (en) * | 1995-01-26 | 1995-03-15 | Nycomed Imaging As | Contrast agents |
| JPH10512877A (ja) * | 1995-01-26 | 1998-12-08 | ニコムド イメージング エイ/エス | ビスマス化合物 |
| IT1283650B1 (it) * | 1996-08-02 | 1998-04-23 | Bracco Spa | Chelati paramagnetici ad alta relassivita' in siero |
| US6458337B1 (en) | 1996-08-02 | 2002-10-01 | Dibra S.P.A | Diagnostic imaging contrast agent with improved in serum relaxivity |
| IT1290417B1 (it) * | 1996-08-02 | 1998-12-03 | Bracco Spa | Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed |
| US6403055B1 (en) | 1996-08-02 | 2002-06-11 | Dibra S.P.A. | Diagnostic imaging contrast agent with improved in serum relaxivity |
| US6558669B1 (en) | 1996-08-28 | 2003-05-06 | Immunomedics, Inc. | Stable radioiodine conjugates and methods for their synthesis |
| US7521531B2 (en) | 1996-08-28 | 2009-04-21 | Immunomedics, Inc. | Methods for the purification of stable radioiodine conjugates |
| JP4432000B2 (ja) | 1996-12-23 | 2010-03-17 | ブラッコ・リサーチ・ソシエテ・アノニム | 患者の消化管の視覚化におけるmri造影の増加用組成物 |
| DE19719033C1 (de) * | 1997-04-29 | 1999-01-28 | Schering Ag | Ionenpaare, Verfahren zu ihrer Herstellung und ihre Verwendung als Kontrastmittel |
| US6019959A (en) * | 1997-07-31 | 2000-02-01 | Schering Aktiengesellschaft | Oligomeric compounds that contain perfluoroalkyl, process for their production, and their use in NMR diagnosis |
| US7632651B2 (en) | 1997-09-15 | 2009-12-15 | Mds Analytical Technologies (Us) Inc. | Molecular modification assays |
| US6153655A (en) | 1998-04-17 | 2000-11-28 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| US6767741B1 (en) * | 1999-08-27 | 2004-07-27 | Invitrogen Corporation | Metal binding compounds and their use in cell culture medium compositions |
| ATE378342T1 (de) * | 2001-02-20 | 2007-11-15 | Enzon Inc | Terminal verzweigte, polymere linker und diese enthaltende polymere konjugate |
| DE10127126A1 (de) * | 2001-06-05 | 2002-12-19 | Forschungszentrum Juelich Gmbh | Geschützte Tyrosinderivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von O-(2-[·18·F]-Fluorethyl)-L-tyrosin |
| US6627394B2 (en) | 2001-07-19 | 2003-09-30 | Common Sense Ltd. | Diagnostic pad |
| WO2006039505A2 (en) | 2004-09-30 | 2006-04-13 | Molecular Devices Corporation | Luminescent lanthanide complexes |
| GB0423506D0 (en) * | 2004-10-22 | 2004-11-24 | Univ Belfast | Light emitting complex salts |
| EP3492116B1 (en) | 2011-06-06 | 2022-03-23 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University | Bismuth particle x-ray contrast agents |
| WO2013171048A1 (en) * | 2012-05-18 | 2013-11-21 | Bayer Pharma Aktiengesellschaft | Bis azainositol heavy metal complexes for x-ray imaging |
| BR102013023479B1 (pt) * | 2013-09-12 | 2022-07-26 | Uniao Brasileira De Educação E Assistência | Processo de síntese de compostos de coordenação à base de lantanídeo |
| CN109613177B (zh) | 2014-07-01 | 2021-08-20 | 科蒙森斯公司 | 用于鉴定羊水的诊断组合物 |
| EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
| ES2814555T3 (es) | 2016-11-28 | 2021-03-29 | Bayer Pharma AG | Compuestos de quelato de gadolinio con alta relaxividad para usar en la obtención de imágenes por resonancia magnética |
| JP7120802B2 (ja) | 2017-07-20 | 2022-08-17 | 株式会社神戸製鋼所 | 流体流通装置及びその流通異常検知方法 |
| JP6836471B2 (ja) | 2017-07-20 | 2021-03-03 | 株式会社神戸製鋼所 | 流体流通装置 |
| CN107573291A (zh) * | 2017-10-27 | 2018-01-12 | 上海司太立制药有限公司 | 一种钆塞酸二钠配体杂质的制备方法和用途 |
| KR102934987B1 (ko) | 2018-11-23 | 2026-03-09 | 바이엘 악티엔게젤샤프트 | 조영 매체의 제형 및 그의 제조 방법 |
| EP4059925A1 (en) | 2021-03-15 | 2022-09-21 | Bayer Aktiengesellschaft | New contrast agent for use in magnetic resonance imaging |
| EP4335462A1 (en) | 2022-09-09 | 2024-03-13 | Bayer AG | Contrast agents for use in diagnostic computed tomography imaging |
| EP4335840A1 (en) | 2022-09-09 | 2024-03-13 | Bayer Aktiengesellschaft | New contrast agents for use in diagnostic imaging |
| CN117820145A (zh) * | 2023-12-29 | 2024-04-05 | 常州天地人和生物科技有限公司 | 一种金属螯合亲和填料配基的合成工艺 |
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| GB1374979A (en) * | 1970-12-21 | 1974-11-20 | Nat Res Dev | 3,5-dioxopiperazine derivatives |
| US3994966A (en) * | 1972-09-28 | 1976-11-30 | The Board Of Trustees Of The Leland Stanford Junior University | Chelating agents |
| US4622420A (en) * | 1980-03-18 | 1986-11-11 | The Regents Of The University Of California | Chelating agents and method |
| US4339426A (en) * | 1980-03-18 | 1982-07-13 | Regents Of The University Of California | Bleomycin analog |
| US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
| US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
| DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
| US4652519A (en) * | 1983-02-03 | 1987-03-24 | Yeda Research And Development Company Limited | Bifunctional chelating agents and process for their production |
| DE3324235A1 (de) * | 1983-07-01 | 1985-01-10 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue komplexbildner, komplexe und komplexsalze |
| US4672028A (en) * | 1984-05-23 | 1987-06-09 | Icn Micromedic Systems, Inc. | Compositions and method for simultaneous multiple array of analytes using radioisotope chelate labels |
| US4824986A (en) * | 1985-04-26 | 1989-04-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Metal chelate protein conjugate |
| US4899755A (en) * | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
| US4880008A (en) * | 1985-05-08 | 1989-11-14 | The General Hospital Corporation | Vivo enhancement of NMR relaxivity |
| US5250285A (en) * | 1985-05-08 | 1993-10-05 | The General Hospital Corporation | Hydroxy-aryl metal chelates for diagnostic NMR imaging |
| IT1213029B (it) * | 1986-01-30 | 1989-12-07 | Bracco Ind Chimica Spa | Chelati di ioni metallici paramagnetici. |
| IL83966A (en) * | 1986-09-26 | 1992-03-29 | Schering Ag | Amides of aminopolycarboxylic acids and pharmaceutical compositions containing them |
| IT1224416B (it) * | 1987-12-24 | 1990-10-04 | Bracco Ind Chimica Spa | Chelanti macrociclici e loro chelati |
| US5057302A (en) * | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
| US5482700A (en) * | 1987-03-31 | 1996-01-09 | Schering Aktiengesellschaft | Substituted polyamino, polycarboxy complexing agent dimers for MRI and X-ray contrast |
| DE3710730A1 (de) * | 1987-03-31 | 1988-10-20 | Schering Ag | Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
| JP2833766B2 (ja) * | 1987-07-16 | 1998-12-09 | ニユコメド・アクシエセルカペト | アミノポリカルボン酸およびその誘導体 |
| DE3728525A1 (de) * | 1987-08-24 | 1989-03-16 | Schering Ag | Mehrkernige substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
| US5399340A (en) * | 1987-09-24 | 1995-03-21 | Schering Aktiengesellschaft | Use of amide complex compounds |
| US5137711A (en) * | 1988-07-19 | 1992-08-11 | Mallickrodt Medical, Inc. | Paramagnetic dtpa and edta alkoxyalkylamide complexes as mri agents |
| US5334371A (en) * | 1988-07-20 | 1994-08-02 | Schering Aktiengesellschaft | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI |
| US5342604A (en) * | 1988-10-31 | 1994-08-30 | The Dow Chemical Company | Complexes possessing ortho ligating functionality |
| PH31170A (en) * | 1988-10-31 | 1998-03-20 | Dow Chemical Co | Chelants possesing ortho ligating functionality and complexes thereof. |
| US5101041A (en) * | 1989-04-26 | 1992-03-31 | The Curators Of The University Of Missouri | Triamines and their derivatives as bifunctional chelating agents |
| US5695739A (en) * | 1989-06-30 | 1997-12-09 | Schering Aktiengesellschaft | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production |
| DE3922005A1 (de) * | 1989-06-30 | 1991-01-10 | Schering Ag | Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
| DE4011684A1 (de) * | 1990-04-06 | 1991-10-10 | Schering Ag | Dtpa-monoamide, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
| GB9122984D0 (en) * | 1991-10-30 | 1991-12-18 | Salutar Inc | Contrast media |
| US5385893A (en) * | 1993-05-06 | 1995-01-31 | The Dow Chemical Company | Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents |
| JPH08510458A (ja) * | 1993-06-02 | 1996-11-05 | ブラッコ エッセ.ピ.ア. | 沃素化された常磁性キレートおよびそれらの造影剤としての使用法 |
| US5358704A (en) * | 1993-09-30 | 1994-10-25 | Bristol-Myers Squibb | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents |
| EP0731797B1 (en) * | 1993-12-03 | 1999-09-08 | BRACCO S.p.A. | Paramagnetic chelates for nuclear magnetic resonance diagnosis |
-
1995
- 1995-06-06 US US08/487,094 patent/US5672335A/en not_active Expired - Fee Related
- 1995-11-20 JP JP8517148A patent/JPH10511934A/ja not_active Withdrawn
- 1995-11-20 AU AU42546/96A patent/AU4254696A/en not_active Abandoned
- 1995-11-20 WO PCT/DE1995/001644 patent/WO1996016677A2/de not_active Ceased
- 1995-11-20 SK SK689-97A patent/SK68997A3/sk unknown
- 1995-11-20 PL PL95320462A patent/PL320462A1/xx unknown
- 1995-11-20 HU HU9702058A patent/HUT77284A/hu unknown
- 1995-11-20 JP JP8517856A patent/JPH10509961A/ja not_active Withdrawn
- 1995-11-20 EP EP95940988A patent/EP0794938A1/de not_active Ceased
- 1995-11-20 CN CN95196529A patent/CN1167444A/zh active Pending
- 1995-11-20 MX MX9703880A patent/MX9703880A/es unknown
- 1995-11-20 WO PCT/EP1995/004549 patent/WO1996016929A1/de not_active Ceased
- 1995-11-20 WO PCT/EP1995/004548 patent/WO1996016928A1/de not_active Ceased
- 1995-11-20 AU AU42994/96A patent/AU4299496A/en not_active Abandoned
- 1995-11-20 CZ CZ971668A patent/CZ166897A3/cs unknown
- 1995-11-20 AU AU39227/95A patent/AU3922795A/en not_active Abandoned
- 1995-11-20 FI FI972286A patent/FI972286A0/fi unknown
- 1995-11-20 CA CA002206576A patent/CA2206576A1/en not_active Abandoned
- 1995-11-20 CA CA002206522A patent/CA2206522A1/en not_active Abandoned
- 1995-11-20 FI FI972288A patent/FI972288L/fi unknown
- 1995-11-20 JP JP8518026A patent/JPH11503405A/ja active Pending
- 1995-11-20 CA CA002206397A patent/CA2206397A1/en not_active Abandoned
- 1995-11-20 EP EP95941616A patent/EP0794939A1/de not_active Withdrawn
- 1995-11-20 FI FI972287A patent/FI972287L/fi unknown
- 1995-11-20 EP EP95936963A patent/EP0794799A2/de not_active Withdrawn
- 1995-11-30 US US08/565,024 patent/US5885548A/en not_active Expired - Fee Related
- 1995-11-30 US US08/565,397 patent/US5853699A/en not_active Expired - Fee Related
- 1995-11-30 IL IL11620895A patent/IL116208A0/xx unknown
- 1995-11-30 IL IL11620995A patent/IL116209A0/xx unknown
- 1995-11-30 IL IL11620695A patent/IL116206A0/xx unknown
- 1995-11-30 US US08/565,025 patent/US5746995A/en not_active Expired - Fee Related
-
1997
- 1997-05-29 NO NO972459A patent/NO972459L/no unknown
- 1997-05-29 NO NO972460A patent/NO972460L/no unknown
- 1997-05-29 NO NO972457A patent/NO972457L/no unknown
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