NO972460L - Nye substituerte DTPA-derivater, deres metallkomplekser, farmasöytiske midler inneholdende metallkompleksene samt deres anvendelse ved diagnostikk og terapi - Google Patents
Nye substituerte DTPA-derivater, deres metallkomplekser, farmasöytiske midler inneholdende metallkompleksene samt deres anvendelse ved diagnostikk og terapiInfo
- Publication number
- NO972460L NO972460L NO972460A NO972460A NO972460L NO 972460 L NO972460 L NO 972460L NO 972460 A NO972460 A NO 972460A NO 972460 A NO972460 A NO 972460A NO 972460 L NO972460 L NO 972460L
- Authority
- NO
- Norway
- Prior art keywords
- metal complexes
- diagnostics
- therapy
- new substituted
- pharmaceuticals containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Radiology & Medical Imaging (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pathology (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Colloid Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Abstract
Nye dietylentriaminpentaeddik- syrederivater, deres komplekser og komplekssaltEr, inneholdende et grunn- stoff med ordenstall 20-32, 39-51 eller 57¿83, farmasøytiske midler innehold- ende disse forbindelser, deres fremstilling og anvendelse som kontrast- midler og motgift.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35108694A | 1994-11-30 | 1994-11-30 | |
| US38740895A | 1995-02-13 | 1995-02-13 | |
| PCT/EP1995/004548 WO1996016928A1 (de) | 1994-11-30 | 1995-11-20 | Neuartig substituierte dtpa-derivate, deren metallkomplexe, diese komplexe enthaltende pharmazeutische mittel und deren verwendung in der diagnostik und therapie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO972460D0 NO972460D0 (no) | 1997-05-29 |
| NO972460L true NO972460L (no) | 1997-05-29 |
Family
ID=26996938
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO972457A NO972457L (no) | 1994-11-30 | 1997-05-29 | Anvendelse av metallkomplekser som lever- og galleröntgendiagnostika i datatomografien |
| NO972459A NO972459L (no) | 1994-11-30 | 1997-05-29 | Nye flersubst DTPA-derivater og deres metallkomplekser, farmasöytiske preparater inneh slike komplekser, deres anv ved diagnostikk og terapi, fremg for fremst av de kompleksdannende midler og komplekser, samt fremg for frems av de farmasöytiske |
| NO972460A NO972460L (no) | 1994-11-30 | 1997-05-29 | Nye substituerte DTPA-derivater, deres metallkomplekser, farmasöytiske midler inneholdende metallkompleksene samt deres anvendelse ved diagnostikk og terapi |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO972457A NO972457L (no) | 1994-11-30 | 1997-05-29 | Anvendelse av metallkomplekser som lever- og galleröntgendiagnostika i datatomografien |
| NO972459A NO972459L (no) | 1994-11-30 | 1997-05-29 | Nye flersubst DTPA-derivater og deres metallkomplekser, farmasöytiske preparater inneh slike komplekser, deres anv ved diagnostikk og terapi, fremg for fremst av de kompleksdannende midler og komplekser, samt fremg for frems av de farmasöytiske |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US5672335A (no) |
| EP (3) | EP0794799A2 (no) |
| JP (3) | JPH10511934A (no) |
| CN (1) | CN1167444A (no) |
| AU (3) | AU3922795A (no) |
| CA (3) | CA2206576A1 (no) |
| CZ (1) | CZ166897A3 (no) |
| FI (3) | FI972286A0 (no) |
| HU (1) | HUT77284A (no) |
| IL (3) | IL116209A0 (no) |
| MX (1) | MX9703880A (no) |
| NO (3) | NO972457L (no) |
| PL (1) | PL320462A1 (no) |
| SK (1) | SK68997A3 (no) |
| WO (3) | WO1996016928A1 (no) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10512877A (ja) * | 1995-01-26 | 1998-12-08 | ニコムド イメージング エイ/エス | ビスマス化合物 |
| GB9501560D0 (en) * | 1995-01-26 | 1995-03-15 | Nycomed Imaging As | Contrast agents |
| IT1283650B1 (it) * | 1996-08-02 | 1998-04-23 | Bracco Spa | Chelati paramagnetici ad alta relassivita' in siero |
| IT1290417B1 (it) * | 1996-08-02 | 1998-12-03 | Bracco Spa | Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed |
| US6458337B1 (en) | 1996-08-02 | 2002-10-01 | Dibra S.P.A | Diagnostic imaging contrast agent with improved in serum relaxivity |
| US6403055B1 (en) | 1996-08-02 | 2002-06-11 | Dibra S.P.A. | Diagnostic imaging contrast agent with improved in serum relaxivity |
| US7521531B2 (en) | 1996-08-28 | 2009-04-21 | Immunomedics, Inc. | Methods for the purification of stable radioiodine conjugates |
| US6558669B1 (en) | 1996-08-28 | 2003-05-06 | Immunomedics, Inc. | Stable radioiodine conjugates and methods for their synthesis |
| US6060040A (en) * | 1996-12-23 | 2000-05-09 | Bracco Research S.A. | Cross-linked polymeric compositions for increasing the MRI contrast in visualising the digestive tract of patients |
| DE19719033C1 (de) * | 1997-04-29 | 1999-01-28 | Schering Ag | Ionenpaare, Verfahren zu ihrer Herstellung und ihre Verwendung als Kontrastmittel |
| US6019959A (en) * | 1997-07-31 | 2000-02-01 | Schering Aktiengesellschaft | Oligomeric compounds that contain perfluoroalkyl, process for their production, and their use in NMR diagnosis |
| US7632651B2 (en) | 1997-09-15 | 2009-12-15 | Mds Analytical Technologies (Us) Inc. | Molecular modification assays |
| US6153655A (en) | 1998-04-17 | 2000-11-28 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| US6767741B1 (en) | 1999-08-27 | 2004-07-27 | Invitrogen Corporation | Metal binding compounds and their use in cell culture medium compositions |
| EP1362053B1 (en) * | 2001-02-20 | 2007-11-14 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| DE10127126A1 (de) * | 2001-06-05 | 2002-12-19 | Forschungszentrum Juelich Gmbh | Geschützte Tyrosinderivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von O-(2-[·18·F]-Fluorethyl)-L-tyrosin |
| US6627394B2 (en) | 2001-07-19 | 2003-09-30 | Common Sense Ltd. | Diagnostic pad |
| WO2006039505A2 (en) | 2004-09-30 | 2006-04-13 | Molecular Devices Corporation | Luminescent lanthanide complexes |
| GB0423506D0 (en) * | 2004-10-22 | 2004-11-24 | Univ Belfast | Light emitting complex salts |
| EP2717934A4 (en) * | 2011-06-06 | 2015-01-14 | Oregon State | X-RAY CONTRACTS FROM WISMUT PARTICLES |
| US20150132229A1 (en) * | 2012-05-18 | 2015-05-14 | Bayer Pharma Aktiengesellschaft | Bis azainositol heavy metal complexes for x-ray imaging |
| BR102013023479B1 (pt) * | 2013-09-12 | 2022-07-26 | Uniao Brasileira De Educação E Assistência | Processo de síntese de compostos de coordenação à base de lantanídeo |
| CN105277656B (zh) | 2014-07-01 | 2018-12-25 | 科蒙森斯公司 | 用于鉴定羊水的诊断组合物 |
| EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
| RU2755181C2 (ru) | 2016-11-28 | 2021-09-14 | Байер Фарма Акциенгезельшафт | Новые хелатные соединения гадолиния с высокой релаксивностью для применения в магнитно-резонансной визуализации |
| JP6836471B2 (ja) | 2017-07-20 | 2021-03-03 | 株式会社神戸製鋼所 | 流体流通装置 |
| JP7120802B2 (ja) | 2017-07-20 | 2022-08-17 | 株式会社神戸製鋼所 | 流体流通装置及びその流通異常検知方法 |
| CN107573291A (zh) * | 2017-10-27 | 2018-01-12 | 上海司太立制药有限公司 | 一种钆塞酸二钠配体杂质的制备方法和用途 |
| IL321215B2 (en) | 2018-11-23 | 2026-05-01 | Bayer Ag | Contrast media formulation and process for its preparation |
| EP4059925A1 (en) | 2021-03-15 | 2022-09-21 | Bayer Aktiengesellschaft | New contrast agent for use in magnetic resonance imaging |
| EP4335840A1 (en) | 2022-09-09 | 2024-03-13 | Bayer Aktiengesellschaft | New contrast agents for use in diagnostic imaging |
| EP4335462A1 (en) | 2022-09-09 | 2024-03-13 | Bayer AG | Contrast agents for use in diagnostic computed tomography imaging |
| CN117820145A (zh) * | 2023-12-29 | 2024-04-05 | 常州天地人和生物科技有限公司 | 一种金属螯合亲和填料配基的合成工艺 |
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| GB1374979A (en) * | 1970-12-21 | 1974-11-20 | Nat Res Dev | 3,5-dioxopiperazine derivatives |
| US3994966A (en) * | 1972-09-28 | 1976-11-30 | The Board Of Trustees Of The Leland Stanford Junior University | Chelating agents |
| US4622420A (en) * | 1980-03-18 | 1986-11-11 | The Regents Of The University Of California | Chelating agents and method |
| US4339426A (en) * | 1980-03-18 | 1982-07-13 | Regents Of The University Of California | Bleomycin analog |
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| US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
| US4652519A (en) * | 1983-02-03 | 1987-03-24 | Yeda Research And Development Company Limited | Bifunctional chelating agents and process for their production |
| DE3324235A1 (de) * | 1983-07-01 | 1985-01-10 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue komplexbildner, komplexe und komplexsalze |
| US4672028A (en) * | 1984-05-23 | 1987-06-09 | Icn Micromedic Systems, Inc. | Compositions and method for simultaneous multiple array of analytes using radioisotope chelate labels |
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| IT1213029B (it) * | 1986-01-30 | 1989-12-07 | Bracco Ind Chimica Spa | Chelati di ioni metallici paramagnetici. |
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| US5057302A (en) * | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
| DE3710730A1 (de) * | 1987-03-31 | 1988-10-20 | Schering Ag | Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
| US5482700A (en) * | 1987-03-31 | 1996-01-09 | Schering Aktiengesellschaft | Substituted polyamino, polycarboxy complexing agent dimers for MRI and X-ray contrast |
| IE61746B1 (en) * | 1987-07-16 | 1994-11-30 | Nycomed Imaging As | Aminopolycarboxylic acids and derivatives thereof |
| DE3728525A1 (de) * | 1987-08-24 | 1989-03-16 | Schering Ag | Mehrkernige substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
| US5399340A (en) * | 1987-09-24 | 1995-03-21 | Schering Aktiengesellschaft | Use of amide complex compounds |
| US5137711A (en) * | 1988-07-19 | 1992-08-11 | Mallickrodt Medical, Inc. | Paramagnetic dtpa and edta alkoxyalkylamide complexes as mri agents |
| US5334371A (en) * | 1988-07-20 | 1994-08-02 | Schering Aktiengesellschaft | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI |
| US5342604A (en) * | 1988-10-31 | 1994-08-30 | The Dow Chemical Company | Complexes possessing ortho ligating functionality |
| NZ231180A (en) * | 1988-10-31 | 1994-11-25 | Dow Chemical Co | Bifunctional chelants;complexes,conjugates and pharmaceutical compositions thereof |
| US5101041A (en) * | 1989-04-26 | 1992-03-31 | The Curators Of The University Of Missouri | Triamines and their derivatives as bifunctional chelating agents |
| US5695739A (en) * | 1989-06-30 | 1997-12-09 | Schering Aktiengesellschaft | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production |
| DE3922005A1 (de) * | 1989-06-30 | 1991-01-10 | Schering Ag | Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
| DE4011684A1 (de) * | 1990-04-06 | 1991-10-10 | Schering Ag | Dtpa-monoamide, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
| GB9122984D0 (en) * | 1991-10-30 | 1991-12-18 | Salutar Inc | Contrast media |
| US5385893A (en) * | 1993-05-06 | 1995-01-31 | The Dow Chemical Company | Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents |
| WO1994027644A1 (en) * | 1993-06-02 | 1994-12-08 | Bracco S.P.A. | Iodinated paramagnetic chelates, and their use as contrast agents |
| US5358704A (en) * | 1993-09-30 | 1994-10-25 | Bristol-Myers Squibb | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents |
| WO1995015319A1 (en) * | 1993-12-03 | 1995-06-08 | Bracco S.P.A. | Paramagnetic chelates for nuclear magnetic resonance diagnosis |
-
1995
- 1995-06-06 US US08/487,094 patent/US5672335A/en not_active Expired - Fee Related
- 1995-11-20 FI FI972286A patent/FI972286A0/fi unknown
- 1995-11-20 FI FI972287A patent/FI972287L/fi unknown
- 1995-11-20 CA CA002206576A patent/CA2206576A1/en not_active Abandoned
- 1995-11-20 AU AU39227/95A patent/AU3922795A/en not_active Abandoned
- 1995-11-20 PL PL95320462A patent/PL320462A1/xx unknown
- 1995-11-20 CZ CZ971668A patent/CZ166897A3/cs unknown
- 1995-11-20 MX MX9703880A patent/MX9703880A/es unknown
- 1995-11-20 WO PCT/EP1995/004548 patent/WO1996016928A1/de not_active Ceased
- 1995-11-20 CA CA002206522A patent/CA2206522A1/en not_active Abandoned
- 1995-11-20 CA CA002206397A patent/CA2206397A1/en not_active Abandoned
- 1995-11-20 AU AU42994/96A patent/AU4299496A/en not_active Abandoned
- 1995-11-20 WO PCT/EP1995/004549 patent/WO1996016929A1/de not_active Ceased
- 1995-11-20 CN CN95196529A patent/CN1167444A/zh active Pending
- 1995-11-20 WO PCT/DE1995/001644 patent/WO1996016677A2/de not_active Ceased
- 1995-11-20 SK SK689-97A patent/SK68997A3/sk unknown
- 1995-11-20 AU AU42546/96A patent/AU4254696A/en not_active Abandoned
- 1995-11-20 EP EP95936963A patent/EP0794799A2/de not_active Withdrawn
- 1995-11-20 JP JP8517148A patent/JPH10511934A/ja not_active Withdrawn
- 1995-11-20 EP EP95941616A patent/EP0794939A1/de not_active Withdrawn
- 1995-11-20 JP JP8518026A patent/JPH11503405A/ja active Pending
- 1995-11-20 JP JP8517856A patent/JPH10509961A/ja not_active Withdrawn
- 1995-11-20 FI FI972288A patent/FI972288L/fi unknown
- 1995-11-20 HU HU9702058A patent/HUT77284A/hu unknown
- 1995-11-20 EP EP95940988A patent/EP0794938A1/de not_active Ceased
- 1995-11-30 IL IL11620995A patent/IL116209A0/xx unknown
- 1995-11-30 IL IL11620895A patent/IL116208A0/xx unknown
- 1995-11-30 US US08/565,025 patent/US5746995A/en not_active Expired - Fee Related
- 1995-11-30 US US08/565,397 patent/US5853699A/en not_active Expired - Fee Related
- 1995-11-30 IL IL11620695A patent/IL116206A0/xx unknown
- 1995-11-30 US US08/565,024 patent/US5885548A/en not_active Expired - Fee Related
-
1997
- 1997-05-29 NO NO972457A patent/NO972457L/no unknown
- 1997-05-29 NO NO972459A patent/NO972459L/no unknown
- 1997-05-29 NO NO972460A patent/NO972460L/no unknown
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