NO980923L - Optisk aktivt fenylpyrimidin-derivat som analgetisk middel - Google Patents

Optisk aktivt fenylpyrimidin-derivat som analgetisk middel

Info

Publication number: NO980923L
Authority: NO; Norway
Prior art keywords: analgesic; optically active; phenylpyrimidine derivative; active phenylpyrimidine; derivative
Prior art date: 1995-09-05

Application number

NO980923A

Other languages

English (en)

Norwegian (no)

Other versions

NO980923D0 (no

Inventor

Malcolm Stuart Nobbs

Sandra Jane Rodgers

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-05

Filing date

1998-03-04

Publication date

1998-05-04

1998-03-04 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1998-03-04 Publication of NO980923D0 publication Critical patent/NO980923D0/no

1998-05-04 Publication of NO980923L publication Critical patent/NO980923L/no

Links

OXPDQFOKSZYEMJ-UHFFFAOYSA-N 2-phenylpyrimidine Chemical class C1=CC=CC=C1C1=NC=CC=N1 OXPDQFOKSZYEMJ-UHFFFAOYSA-N 0.000 title 1
230000000202 analgesic effect Effects 0.000 title 1
208000020925 Bipolar disease Diseases 0.000 abstract 1
CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
229940035676 analgesics Drugs 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
229940125681 anticonvulsant agent Drugs 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
230000002496 gastric effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO980923A 1995-09-05 1998-03-04 Optisk aktivt fenylpyrimidin-derivat som analgetisk middel NO980923L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9518027.9A GB9518027D0 (en)	1995-09-05	1995-09-05	Pharmacologically active compound
PCT/EP1996/003856 WO1997009317A2 (en)	1995-09-05	1996-09-03	Optically active phenyl pyrimidine derivative as analgesic agent

Publications (2)

Publication Number	Publication Date
NO980923D0 NO980923D0 (no)	1998-03-04
NO980923L true NO980923L (no)	1998-05-04

Family

ID=10780172

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO980923A NO980923L (no)	1995-09-05	1998-03-04	Optisk aktivt fenylpyrimidin-derivat som analgetisk middel

Country Status (32)

Country	Link
US (1)	US6124308A (is)
EP (1)	EP0879230B1 (is)
JP (1)	JPH11512108A (is)
KR (1)	KR19990044397A (is)
CN (1)	CN1200729A (is)
AP (1)	AP640A (is)
AR (1)	AR004192A1 (is)
AT (1)	ATE203523T1 (is)
AU (1)	AU710091B2 (is)
BG (1)	BG65102B1 (is)
BR (1)	BR9610388A (is)
CA (1)	CA2230362A1 (is)
CO (1)	CO4750651A1 (is)
CZ (1)	CZ65598A3 (is)
DE (1)	DE69614150T2 (is)
EA (1)	EA000695B1 (is)
ES (1)	ES2160834T3 (is)
GB (1)	GB9518027D0 (is)
HR (1)	HRP960399A2 (is)
HU (1)	HUP9901260A3 (is)
ID (1)	ID17274A (is)
IL (1)	IL123414A0 (is)
IS (1)	IS4673A (is)
NO (1)	NO980923L (is)
NZ (1)	NZ318390A (is)
PL (1)	PL325329A1 (is)
SK (1)	SK28598A3 (is)
TR (1)	TR199800386T1 (is)
TW (1)	TW367326B (is)
WO (1)	WO1997009317A2 (is)
YU (1)	YU49796A (is)
ZA (1)	ZA967466B (is)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR016212A1 (es) *	1998-04-28	2001-06-20	Astra Ab	Uso de compuestos farmaceuticos que tienen una actividad antagonista de nmda para preparar un medicamento para el tratamiento del sindrome de intestino irritable (ibs), y composiciones farmaceuticas
EP1085879A2 (en) *	1998-06-08	2001-03-28	Advanced Medicine, Inc.	Multibinding agents that modulate the 5-ht transporter
US6420354B1 (en)	1998-06-08	2002-07-16	Advanced Medicine, Inc.	Sodium channel drugs and uses
GB9907965D0 (en) *	1999-04-09	1999-06-02	Glaxo Group Ltd	Medical use
US6479498B1 (en)	1999-06-04	2002-11-12	Theravance, Inc.	Sodium channel drugs and uses
AU7349301A (en) *	2000-07-21	2002-02-05	Ortho Mcneil Pharm Inc	Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
IL157608A0 (en) *	2001-02-27	2004-03-28	Teva Pharma	New crystal forms of lamotrigine and processes for their preparations
EP2316468A1 (en)	2002-02-22	2011-05-04	Shire LLC	Delivery system and methods for protecting and administering dextroamphetamine
CA2483103A1 (en) *	2002-04-23	2003-11-06	Teva Pharmaceutical Industries Ltd.	Pharmaceutical composition containing lamotrigine particles of defined morphology
WO2004066987A2 (en) *	2003-01-30	2004-08-12	Dynogen Pharmaceuticals, Inc.	Use of sodium channel modulators for treating gastrointestinal tract disorders
GB0603087D0 (en) *	2006-02-15	2006-03-29	Glaxo Group Ltd	Novel use
EP2117538A1 (en) *	2007-01-24	2009-11-18	Glaxo Group Limited	Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-)
GB201111712D0 (en)	2011-07-08	2011-08-24	Gosforth Ct Holdings Pty Ltd	Pharmaceutical compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK153787C (da) *	1979-06-01	1989-01-16	Wellcome Found	Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved
FI895821A7 (fi) *	1988-12-07	1990-06-08	The Wellcome Foundation Ltd	Farmaseuttisesti aktivisia CNS-yhdisteitä

1995
- 1995-09-05 GB GBGB9518027.9A patent/GB9518027D0/en active Pending
1996
- 1996-09-03 EP EP96931006A patent/EP0879230B1/en not_active Expired - Lifetime
- 1996-09-03 AT AT96931006T patent/ATE203523T1/de not_active IP Right Cessation
- 1996-09-03 JP JP9510854A patent/JPH11512108A/ja not_active Ceased
- 1996-09-03 EA EA199800189A patent/EA000695B1/ru not_active IP Right Cessation
- 1996-09-03 NZ NZ318390A patent/NZ318390A/xx unknown
- 1996-09-03 SK SK285-98A patent/SK28598A3/sk unknown
- 1996-09-03 ES ES96931006T patent/ES2160834T3/es not_active Expired - Lifetime
- 1996-09-03 CA CA002230362A patent/CA2230362A1/en not_active Abandoned
- 1996-09-03 CN CN96197823A patent/CN1200729A/zh active Pending
- 1996-09-03 CO CO96046885A patent/CO4750651A1/es unknown
- 1996-09-03 HU HU9901260A patent/HUP9901260A3/hu unknown
- 1996-09-03 TR TR1998/00386T patent/TR199800386T1/xx unknown
- 1996-09-03 DE DE69614150T patent/DE69614150T2/de not_active Expired - Lifetime
- 1996-09-03 CZ CZ98655A patent/CZ65598A3/cs unknown
- 1996-09-03 ID IDP962513A patent/ID17274A/id unknown
- 1996-09-03 HR HR9518027.9A patent/HRP960399A2/hr not_active Application Discontinuation
- 1996-09-03 PL PL96325329A patent/PL325329A1/xx unknown
- 1996-09-03 IL IL12341496A patent/IL123414A0/xx unknown
- 1996-09-03 AU AU69865/96A patent/AU710091B2/en not_active Ceased
- 1996-09-03 KR KR1019980701641A patent/KR19990044397A/ko not_active Withdrawn
- 1996-09-03 BR BR9610388A patent/BR9610388A/pt not_active Application Discontinuation
- 1996-09-03 WO PCT/EP1996/003856 patent/WO1997009317A2/en not_active Ceased
- 1996-09-03 US US09/029,162 patent/US6124308A/en not_active Expired - Fee Related
- 1996-09-04 AR ARP960104220A patent/AR004192A1/es unknown
- 1996-09-04 ZA ZA9607466A patent/ZA967466B/xx unknown
- 1996-09-04 YU YU49796A patent/YU49796A/sh unknown
- 1996-09-05 TW TW085110879A patent/TW367326B/zh active
- 1996-09-06 AP APAP/P/1996/000857A patent/AP640A/en active
1998
- 1998-02-23 IS IS4673A patent/IS4673A/is unknown
- 1998-03-04 NO NO980923A patent/NO980923L/no not_active Application Discontinuation
- 1998-03-23 BG BG102342A patent/BG65102B1/bg unknown

Also Published As

Publication number	Publication date
IS4673A (is)	1998-02-23
WO1997009317A2 (en)	1997-03-13
GB9518027D0 (en)	1995-11-08
PL325329A1 (en)	1998-07-20
AU6986596A (en)	1997-03-27
EA199800189A1 (ru)	1998-10-29
DE69614150D1 (de)	2001-08-30
TR199800386T1 (xx)	1998-05-21
NO980923D0 (no)	1998-03-04
HUP9901260A2 (hu)	1999-09-28
EP0879230A2 (en)	1998-11-25
AP640A (en)	1998-04-14
BG65102B1 (bg)	2007-02-28
BG102342A (en)	1998-09-30
HRP960399A2 (en)	1998-04-30
HUP9901260A3 (en)	2001-04-28
ES2160834T3 (es)	2001-11-16
NZ318390A (en)	1999-02-25
AR004192A1 (es)	1998-11-04
AP9600857A0 (en)	1996-10-31
ATE203523T1 (de)	2001-08-15
AU710091B2 (en)	1999-09-16
MX9801680A (es)	1998-05-31
EP0879230B1 (en)	2001-07-25
IL123414A0 (en)	1998-09-24
ZA967466B (en)	1998-04-06
EA000695B1 (ru)	2000-02-28
JPH11512108A (ja)	1999-10-19
US6124308A (en)	2000-09-26
YU49796A (sh)	1999-07-28
WO1997009317A3 (en)	1997-04-03
CN1200729A (zh)	1998-12-02
DE69614150T2 (de)	2001-11-22
CO4750651A1 (es)	1999-03-31
ID17274A (id)	1997-12-18
BR9610388A (pt)	1999-07-06
KR19990044397A (ko)	1999-06-25
SK28598A3 (en)	1998-09-09
CZ65598A3 (cs)	1998-07-15
CA2230362A1 (en)	1997-03-13
TW367326B (en)	1999-08-21

Legal Events

Date	Code	Title	Description
2001-08-13	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
BR0010220A (pt)	2002-05-14	Compostos de pirimidinona
BR0011130A (pt)	2002-03-19	Inibidores de metaloproteases
SE9504661D0 (sv)	1995-12-22	New compounds
NO980923L (no)	1998-05-04	Optisk aktivt fenylpyrimidin-derivat som analgetisk middel
NO971889L (no)	1997-06-23	Forbindelser og sammensetninger for levering av aktive midler
TR200200649T2 (tr)	2002-07-22	Farmasötik özelliklere sahip olan yeni aminodikarboksilik asit türevleri
TR199802296T2 (xx)	1999-02-22	Yeni 2,3 dis�bstit�te-4 (3H)-kinazolinonlar
BR0014078A (pt)	2002-12-31	Inibidores de fator xa
BR9609617B1 (pt)	2010-07-27	derivados de 7h-pirrol[2,3-d]pirimidina, e composição farmacêutica.
DK0624595T3 (da)	1999-05-17	Nor-galdesyrederivater, fremgangsmåde til deres fremstilling og anvendelse af disse forbindelser som lægemidler
FI961809A0 (fi)	1996-04-26	Uudet (R)-5-karbamoyyli-8-fluori-3-N,N-disubstituoitu-amino 3,4-dihydro-2H-1-bentsopyraanit
PL330407A1 (en)	1999-05-10	Substituted cyclopentane compounds useful as neuraminidaze inhibitors
ATE290015T1 (de)	2005-03-15	Cyclosporinderivate, deren herstellung und pharmazeutische zubereitungen
ATE205494T1 (de)	2001-09-15	Pyridylfuran- und pyridylthiphenderivate und deren pharmazeutische verwendung
NO952132D0 (no)	1995-05-30	Farmakologiske aktive pyridin-derivater og deres fremstilling
PT1147110E (pt)	2003-09-30	Derivados de pirazino (aza)-indol
AU697679B2 (en)	1998-10-15	Treatment of tinnitis using neuroprotective agents
AP9701041A0 (en)	1999-01-10	Pyridylpyrrole compounds.
NO996108L (no)	2000-02-10	9-oksinerytromycinderivater
TR200200883T2 (tr)	2002-09-23	2-ikameli 1,1-bifenil-2-karbonamidler, imalat yöntemleri, ilaç olarak kullanılmaları
TR199802060T2 (xx)	1999-01-18	Aminoisokinolinler ve aminopiridin t�revlerinin iltihap �nleyiciler olarak kullan�m�.
CA2040982A1 (en)	1991-10-25	N-(3-fluoro-2-phosphonylmethoxypropyl) derivatives of purine and pyrimidine heterocyclic bases, their preparation and use
BR0213994A (pt)	2004-08-31	Derivados heterocìclicos de glicinamida e seus usos médicos
SE9802208D0 (sv)	1998-06-22	Novel compounds
DK0866791T3 (da)	2002-04-22	Diaminopyrimidiner, farmaceutiske præparater indeholdende disse og deres anvendelse som antibakterielle midler