NO981868L - Preparat og fremgangsmÕte for stabilisering av biologiske materialer ved t°rking uten nedfrysing - Google Patents
Preparat og fremgangsmÕte for stabilisering av biologiske materialer ved t°rking uten nedfrysingInfo
- Publication number
- NO981868L NO981868L NO981868A NO981868A NO981868L NO 981868 L NO981868 L NO 981868L NO 981868 A NO981868 A NO 981868A NO 981868 A NO981868 A NO 981868A NO 981868 L NO981868 L NO 981868L
- Authority
- NO
- Norway
- Prior art keywords
- solution
- freezing
- drying
- preparation
- substance mixtures
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000008014 freezing Effects 0.000 title abstract 2
- 238000007710 freezing Methods 0.000 title abstract 2
- 239000012620 biological material Substances 0.000 title 1
- 238000001035 drying Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000000087 stabilizing effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 3
- 239000011149 active material Substances 0.000 abstract 2
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Drying Of Solid Materials (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Plant Substances (AREA)
- Storage Of Fruits Or Vegetables (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19539574A DE19539574A1 (de) | 1995-10-25 | 1995-10-25 | Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren |
| PCT/EP1996/004627 WO1997015288A2 (de) | 1995-10-25 | 1996-10-24 | Zubereitungen und verfahren zur stabilisierung biologischer materialien mittels trocknungsverfahren ohne einfrieren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO981868D0 NO981868D0 (no) | 1998-04-24 |
| NO981868L true NO981868L (no) | 1998-06-25 |
| NO324728B1 NO324728B1 (no) | 2007-12-03 |
Family
ID=7775640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19981868A NO324728B1 (no) | 1995-10-25 | 1998-04-24 | Fremgangsmate for fremstilling av torre, delvis amorfe produkter, stoffblanding, diagnostisk middel og preparat som omfatter stofflandingen, anvendelse av stoffblandingen til fremstilling av diagnostika og terapeutiske midler og fremgangsmate for stabilisering av biologisk eller terapeutisk aktive materialer |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US7172999B2 (no) |
| EP (1) | EP0857060B1 (no) |
| JP (2) | JPH11513700A (no) |
| KR (1) | KR100466670B1 (no) |
| CN (1) | CN1130196C (no) |
| AT (1) | ATE212541T1 (no) |
| AU (1) | AU712489B2 (no) |
| BR (1) | BR9611265A (no) |
| CA (1) | CA2235243C (no) |
| CZ (1) | CZ293456B6 (no) |
| DE (2) | DE19539574A1 (no) |
| DK (1) | DK0857060T3 (no) |
| ES (1) | ES2170274T3 (no) |
| HU (1) | HU222601B1 (no) |
| IL (1) | IL124204A (no) |
| MX (1) | MX9803264A (no) |
| NO (1) | NO324728B1 (no) |
| NZ (1) | NZ320276A (no) |
| PL (1) | PL190657B1 (no) |
| PT (1) | PT857060E (no) |
| RU (1) | RU2191003C2 (no) |
| SK (1) | SK283664B6 (no) |
| TR (1) | TR199800715T2 (no) |
| WO (1) | WO1997015288A2 (no) |
| ZA (1) | ZA968930B (no) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| DE19539574A1 (de) * | 1995-10-25 | 1997-04-30 | Boehringer Mannheim Gmbh | Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren |
| EP0852951A1 (de) * | 1996-11-19 | 1998-07-15 | Roche Diagnostics GmbH | Stabile lyophilisierte pharmazeutische Zubereitungen von mono- oder polyklonalen Antikörpern |
| EP0913177A1 (de) * | 1997-11-03 | 1999-05-06 | Roche Diagnostics GmbH | Verfahren zur Herstellung trockener, amorpher Produkte enthaltend biologisch aktive Materialien mittels Konvektionstrocknung, insbesondere Sprühtrocknung |
| EP0913178A1 (en) * | 1997-11-03 | 1999-05-06 | Boehringer Mannheim Gmbh | Process for the manufacture of dry, amorphous products comprising biologically active material by means of convection drying and products obtainable by the process |
| BR9905867A (pt) * | 1998-11-06 | 2001-01-23 | Bio Sidus S A | Linhagem celular produtora de eritropoietina humana recombinante e a eritropoietina humana recombinante produzida por esta célula |
| KR100740794B1 (ko) * | 1999-04-09 | 2007-07-20 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 에리트로포이에틴의 약제학적 제형 |
| DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
| EP1290390A1 (en) * | 2000-06-07 | 2003-03-12 | Universal Preservation Technologies, Inc. | Industrial scale barrier technology for preservation of sensitive biological materials |
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| IL162754A0 (en) * | 2002-01-16 | 2005-11-20 | Boehringer Ingelheim Pharma | Bilayer pharmaceutical tablet comprising telmisartane and a diuretic and preparation thereof |
| KR100556503B1 (ko) * | 2002-11-26 | 2006-03-03 | 엘지전자 주식회사 | 건조기의 건조 시간제어 방법 |
| US8377952B2 (en) * | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| US8025899B2 (en) * | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US20080176209A1 (en) * | 2004-04-08 | 2008-07-24 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| US20060099567A1 (en) * | 2004-04-08 | 2006-05-11 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| WO2005113147A2 (en) | 2004-04-08 | 2005-12-01 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| GB0517688D0 (en) * | 2005-08-31 | 2005-10-05 | Cambridge Biostability Ltd | Improvements in the stabilisation of biological materials |
| GB2430880A (en) * | 2005-10-04 | 2007-04-11 | Cambridge Biostability Ltd | Pharmaceutical compositions stabilized in glassy particles |
| GB0523638D0 (en) * | 2005-11-21 | 2005-12-28 | Cambridge Biostability Ltd | Pharmaceutical device for the administration of substances to patients |
| WO2007079147A2 (en) | 2005-12-28 | 2007-07-12 | Advanced Bionutrition Corporation | A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| JP5285617B2 (ja) | 2006-12-18 | 2013-09-11 | アドバンスド バイオニュートリション コーポレーション | 生きたプロバイオティクスを含む乾燥食物製品 |
| US8466187B2 (en) | 2007-09-18 | 2013-06-18 | Thermolife International, Llc | Amino acid compositions |
| EP3266448B1 (en) | 2009-03-27 | 2022-02-16 | Intervet International B.V. | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
| EP2236520A1 (en) * | 2009-03-31 | 2010-10-06 | Leukocare Ag | Stabilizing composition for immobilized biomolecules |
| SG176253A1 (en) | 2009-05-26 | 2011-12-29 | Advanced Bionutrition Corp | Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making |
| AR080428A1 (es) * | 2010-01-20 | 2012-04-11 | Chugai Pharmaceutical Co Ltd | Formulaciones liquidas estabilizadas contentivas de anticuerpos |
| NZ601017A (en) | 2010-01-28 | 2014-07-25 | Advanced Bionutrition Corp | Dry glassy composition comprising a bioactive material |
| US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
| US9376709B2 (en) | 2010-07-26 | 2016-06-28 | Biomatrica, Inc. | Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures |
| EP2598661B1 (en) | 2010-07-26 | 2017-09-27 | Biomatrica, INC. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| CL2011001984A1 (es) | 2010-08-13 | 2012-06-29 | Advanced Bionutrition Corp | Composicion seca estabilizadora para material biologico que comprende carbohidrato, proteinas hidrolizadas de animal o de planta y un componente de acido carboxilico; metodo de preparacion; y formulacion de entrega oral que comprende la composicion seca estabilizadora. |
| CN102408467B (zh) * | 2010-09-26 | 2014-03-05 | 海口维瑅瑷生物研究院 | 真空干燥蛋白的方法、制得的蛋白产品和试剂盒 |
| US12612370B2 (en) | 2011-03-02 | 2026-04-28 | Thermolife International, Llc | Amino acid compositions |
| PL2696865T3 (pl) | 2011-04-13 | 2017-07-31 | Thermolife International, Llc | Sposoby zastosowania N-acetylo beta-alaniny |
| US9725703B2 (en) | 2012-12-20 | 2017-08-08 | Biomatrica, Inc. | Formulations and methods for stabilizing PCR reagents |
| ES2939940T3 (es) | 2014-03-28 | 2023-04-28 | Univ Duke | Tratamiento del cáncer de mama utilizando moduladores selectivos de los receptores de estrógenos |
| WO2015191632A1 (en) | 2014-06-10 | 2015-12-17 | Biomatrica, Inc. | Stabilization of thrombocytes at ambient temperatures |
| US9868944B2 (en) * | 2014-12-19 | 2018-01-16 | Roche Molecular Systems, Inc. | Reaction mixtures |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| MX384826B (es) * | 2015-02-11 | 2025-03-14 | Evah Nutrition Inc | Matriz seca mejorada para incrustar escherichia coli viable, metodo para hacer la misma y uso de la misma. |
| MX384605B (es) | 2015-04-29 | 2025-03-14 | Radius Pharmaceuticals Inc | Combinación de palbociclib y rad1901 para usarse en el tratamiento de cáncer de mama en un sujeto con cáncer positivo a receptor de estrógeno. |
| EP3328215B1 (en) | 2015-07-29 | 2021-07-07 | Advanced BioNutrition Corp. | Stable dry probiotic compositions for special dietary uses |
| US12558395B2 (en) | 2015-07-29 | 2026-02-24 | Advanced Bionutrition Corp. | Stable dry probiotic compositions for special dietary uses |
| ES2946184T3 (es) | 2015-12-08 | 2023-07-13 | Biomatrica Inc | Reducción de la velocidad de eritrosedimentación |
| CN106831466B (zh) * | 2016-12-28 | 2018-05-22 | 安徽省虹升生物股份有限公司 | 一种β-丙氨酸的常规储存方法 |
| EP3565542B1 (en) | 2017-01-05 | 2024-04-10 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad1901-2hcl |
| CA3097058A1 (en) * | 2018-04-16 | 2019-10-24 | Merck Patent Gmbh | Additives for protein formulations to improve thermal stability |
| SG11202013177WA (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals Inc | Polymorphic forms of rad 1901-2hcl |
| US12441745B2 (en) | 2019-02-12 | 2025-10-14 | Radius Pharmaceuticals, Inc. | Processes and compounds |
| US12558423B2 (en) | 2020-05-29 | 2026-02-24 | Chugai Seiyaku Kabushiki Kaisha | Antibody-containing formulation |
| CA3187322A1 (en) * | 2020-07-13 | 2022-01-20 | Merck Patent Gmbh | Viscosity reducing excipients and combinations thereof for highly concentrated protein formulations |
| US11865139B2 (en) | 2020-11-12 | 2024-01-09 | Thermolife International, Llc | Method of treating migraines and headaches |
| JP2024541338A (ja) | 2020-11-12 | 2024-11-08 | サーモライフ インターナショナル, エルエルシー | 血中酸素飽和度を増大させる方法 |
| EP4291206A4 (en) | 2021-02-11 | 2025-01-08 | Thermolife International, LLC | A method of administering nitric oxide gas |
| CN114480129A (zh) * | 2022-01-13 | 2022-05-13 | 力因精准医疗产品(上海)有限公司 | 一种人粪便保存液及使用方法 |
| KR102913374B1 (ko) * | 2022-12-28 | 2026-01-15 | 씨제이제일제당 주식회사 | 발효 제품 제조 방법 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3714353A (en) * | 1959-08-11 | 1973-01-30 | Upjohn Co | THERAPEUTIC COMPOSITIONS COMPRISING A 6 alpha ; 9 alpha -DIFLUORO-11 beta ,17 alpha ,21-TRIHYDROXY-16 alpha -METHYL-1,4-PREGNADIENE-3,20-DIONE AND 21-ACYLATES |
| US3852461A (en) * | 1971-08-04 | 1974-12-03 | Upjohn Co | Benzodiapines used as minor tranquilizers |
| JPS5836954B2 (ja) * | 1980-03-31 | 1983-08-12 | 栄研化学株式会社 | 酵素の安定化剤 |
| JPS5967228A (ja) | 1982-10-07 | 1984-04-16 | Green Cross Corp:The | 寒冷不溶性グロブリンの凍結乾燥方法 |
| JPS6197229A (ja) * | 1984-10-18 | 1986-05-15 | Chugai Pharmaceut Co Ltd | 安定なエリトロポエチン製剤 |
| US4732889A (en) * | 1985-02-06 | 1988-03-22 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for the treatment of the anemia of rheumatoid arthritis |
| US4788072A (en) * | 1985-08-15 | 1988-11-29 | Toshimitsu Kawamura | Method of dehydrating foods |
| US4808617A (en) | 1985-12-18 | 1989-02-28 | Bristol-Myers Company | Lyophilized or precipitated cephalosporin zwitterion and salt combination |
| EP0326618A1 (en) * | 1987-03-04 | 1989-08-09 | Nippon Hypox Laboratories Incorporated | Medicinal composition containing albumin as carrier and process for its preparation |
| DE3729863A1 (de) | 1987-09-05 | 1989-03-16 | Boehringer Mannheim Gmbh | Stabilisierte erythropoietin-lyophilisate |
| US4886742A (en) * | 1987-06-15 | 1989-12-12 | Coulter Corporation | Enzyme immunoassay for detecting HIV antigens in human sera |
| DE3801179A1 (de) * | 1988-01-18 | 1989-07-27 | Hoechst Ag | Stabilisierung von cephalosporinderivaten durch trocknung mit einem stabilisator sowie stabile zubereitungsformen mit cephalosporinderivaten |
| JPH0761955B2 (ja) | 1988-04-28 | 1995-07-05 | 国立予防衛生研究所長 | 凍結乾燥a型肝炎ワクチン |
| CA1339071C (en) | 1988-08-24 | 1997-07-29 | Koichiro Tsuji | Thrombus control agent |
| JPH0296536A (ja) | 1988-09-29 | 1990-04-09 | Green Cross Corp:The | プラスミノゲン乾燥製剤 |
| JP2739584B2 (ja) | 1989-01-06 | 1998-04-15 | 株式会社ミドリ十字 | ウロキナーゼ型プラスミノーゲンアクチベーター乾燥製剤 |
| US5186944A (en) * | 1989-02-15 | 1993-02-16 | Eimei Company Ltd. | Therapeutic medicament for thrombosis |
| CA2028848A1 (en) * | 1989-04-11 | 1990-10-12 | Tapan Audhya | Lyophilized peptide formulations |
| JPH0775519B2 (ja) | 1989-10-06 | 1995-08-16 | 東洋製罐株式会社 | ドライパック包装食品の製造方法 |
| GB9001987D0 (en) * | 1990-01-29 | 1990-03-28 | Janssen Pharmaceutica Nv | Improved cyclodextrin based erythropietin formulation |
| JPH0813750B2 (ja) * | 1990-03-01 | 1996-02-14 | 持田製薬株式会社 | 経口用トロンビン製剤 |
| US5200399A (en) * | 1990-09-14 | 1993-04-06 | Boyce Thompson Institute For Plant Research, Inc. | Method of protecting biological materials from destructive reactions in the dry state |
| US5217741A (en) | 1991-01-25 | 1993-06-08 | Snow Brand Milk Products Co., Ltd. | Solution containing whey protein, whey protein gel, whey protein powder and processed food product produced by using the same |
| AU659645B2 (en) * | 1991-06-26 | 1995-05-25 | Inhale Therapeutic Systems | Storage of materials |
| JP2818834B2 (ja) * | 1991-08-12 | 1998-10-30 | 大塚製薬株式会社 | IL−1α安定化医薬製剤 |
| DE4141351A1 (de) | 1991-12-14 | 1993-06-17 | Basf Ag | Stabile pulverfoermige vitamin- und/oder carotinoid-praeparate und verfahren zu deren herstellung |
| SE9201073D0 (sv) | 1992-04-03 | 1992-04-03 | Kabi Pharmacia Ab | Protein formulation |
| IL105553A (en) | 1992-05-06 | 1998-01-04 | Janssen Pharmaceutica Inc | Solid dosage form comprising a porous network of matrix forming material which disperses rapidly in water |
| IT1254359B (it) | 1992-05-11 | 1995-09-14 | Serono Cesare Ist Ricerca | Composizioni farmaceutiche contenenti il-6 |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| JP3168550B2 (ja) * | 1992-12-02 | 2001-05-21 | 株式会社林原生物化学研究所 | 脱水剤およびそれを用いる含水物の脱水方法並びにその方法で得られる脱水物品 |
| DE4242863A1 (de) * | 1992-12-18 | 1994-06-23 | Boehringer Mannheim Gmbh | Stabile lyophilisierte pharmazeutische Zubereitungen von G-CSF |
| US5354934A (en) * | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
| DE69535897D1 (de) | 1994-03-07 | 2009-01-22 | Nektar Therapeutics | Verfahren und Zusammensetzung für die pulmonale Darreichung von Insulin |
| US5955448A (en) * | 1994-08-19 | 1999-09-21 | Quadrant Holdings Cambridge Limited | Method for stabilization of biological substances during drying and subsequent storage and compositions thereof |
| FR2719479B1 (fr) * | 1994-05-04 | 1996-07-26 | Sanofi Elf | Formulation stable lyophilisée comprenant une protéine: kit de dosage. |
| AU696387B2 (en) | 1994-05-18 | 1998-09-10 | Inhale Therapeutic Systems, Inc. | Methods and compositions for the dry powder formulation of interferons |
| IL116085A (en) | 1994-12-16 | 1999-12-31 | Ortho Pharma Corp | Spray dried erythropoietin |
| AU706195B2 (en) | 1995-04-14 | 1999-06-10 | Inhale Therapeutic Systems | Powdered pharmaceutical formulations having improved dispersibility |
| US5728678A (en) | 1995-06-06 | 1998-03-17 | Nestec Ltd. | Method and composition for providing nutrition to a renal failure patient |
| DE19538687A1 (de) | 1995-10-17 | 1997-04-24 | Boehringer Mannheim Gmbh | Stabile pharmazeutische Darreichungsformen enthaltend Parathormon |
| DE19539574A1 (de) * | 1995-10-25 | 1997-04-30 | Boehringer Mannheim Gmbh | Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren |
-
1995
- 1995-10-25 DE DE19539574A patent/DE19539574A1/de not_active Withdrawn
-
1996
- 1996-10-24 CN CN96199329A patent/CN1130196C/zh not_active Expired - Fee Related
- 1996-10-24 NZ NZ320276A patent/NZ320276A/xx not_active IP Right Cessation
- 1996-10-24 ZA ZA9608930A patent/ZA968930B/xx unknown
- 1996-10-24 AU AU72984/96A patent/AU712489B2/en not_active Ceased
- 1996-10-24 JP JP9516286A patent/JPH11513700A/ja active Pending
- 1996-10-24 IL IL12420496A patent/IL124204A/en not_active IP Right Cessation
- 1996-10-24 US US09/051,918 patent/US7172999B2/en not_active Expired - Fee Related
- 1996-10-24 CZ CZ19981179A patent/CZ293456B6/cs not_active IP Right Cessation
- 1996-10-24 WO PCT/EP1996/004627 patent/WO1997015288A2/de not_active Ceased
- 1996-10-24 HU HU9901314A patent/HU222601B1/hu not_active IP Right Cessation
- 1996-10-24 DK DK96934811T patent/DK0857060T3/da active
- 1996-10-24 KR KR10-1998-0703022A patent/KR100466670B1/ko not_active Expired - Fee Related
- 1996-10-24 SK SK509-98A patent/SK283664B6/sk not_active IP Right Cessation
- 1996-10-24 ES ES96934811T patent/ES2170274T3/es not_active Expired - Lifetime
- 1996-10-24 PL PL96326358A patent/PL190657B1/pl not_active IP Right Cessation
- 1996-10-24 BR BR9611265A patent/BR9611265A/pt not_active IP Right Cessation
- 1996-10-24 DE DE59608684T patent/DE59608684D1/de not_active Revoked
- 1996-10-24 PT PT96934811T patent/PT857060E/pt unknown
- 1996-10-24 RU RU98109886/14A patent/RU2191003C2/ru not_active IP Right Cessation
- 1996-10-24 EP EP96934811A patent/EP0857060B1/de not_active Revoked
- 1996-10-24 AT AT96934811T patent/ATE212541T1/de active
- 1996-10-24 TR TR1998/00715T patent/TR199800715T2/xx unknown
- 1996-10-24 CA CA002235243A patent/CA2235243C/en not_active Expired - Fee Related
-
1998
- 1998-04-24 MX MX9803264A patent/MX9803264A/es not_active IP Right Cessation
- 1998-04-24 NO NO19981868A patent/NO324728B1/no not_active IP Right Cessation
-
2002
- 2002-05-10 US US10/141,960 patent/US20030059468A1/en not_active Abandoned
-
2006
- 2006-06-09 US US11/449,781 patent/US20070020289A1/en not_active Abandoned
-
2007
- 2007-05-28 JP JP2007141138A patent/JP2007236975A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO981868D0 (no) | Preparat og fremgangsmÕte for stabilisering av biologiske materialer ved t÷rking uten nedfrysing | |
| AU584530B2 (en) | Novel azole derivative, process for producing thereof and agriculture and horticultural chemical composition containing the same | |
| FI104177B1 (fi) | Menetelmä terapeuttisesti käyttökelpoisten oligonukleotidien valmistamiseksi | |
| NO972107D0 (no) | Bearbeidet fiskekjött, fiskekjöttmaterial fremstilt ved anvendelse derav, og fremgangsmåte for fremstilling av bearbeidet fiskekjött | |
| CA2253154A1 (en) | Process for the manufacture of amorphous products by means of convection drying | |
| BE880584A (fr) | Nouveaux derives d'imidazole, leur procede de production et composition pharmaceutique les contenant | |
| BE879173A (fr) | Procede de preparation d'un allergene traite par un aldehyde, produit obtenu et son application therapeutique | |
| TR199800334T1 (xx) | Meyve �r�nleri. | |
| IL85428A0 (en) | Novel azole derivative,process for production thereof and agricultural and horticultural chemical composition | |
| FR2306415A1 (fr) | Procede de sechage de produits de fourrage agricoles et de matieres se presentant sous forme de boue | |
| FR2621588B1 (fr) | Nouveaux derives de la 1,1-dioxo 1,2-benzoisothiazol 3-one, leur procede de preparation et leur application comme medicaments | |
| CA2269077A1 (en) | Keratinocyte growth factor-2 products | |
| ATE72942T1 (de) | Verfahren zur herstellung von getrockneten teigwaren. | |
| BE878230A (fr) | Nouveaux derives d'imidazole, leur procede de production et composition pharmaceutique les contenant | |
| BE855275A (fr) | Nouveaux derives aminomethylazoliques, leur procede de preparation et leur application comme substances de croissance des plantes | |
| IE45420L (en) | Functional proteins. | |
| FI884668A7 (fi) | Menetelmä kuivien viljatuotteiden valmistusprosessin parantamiseksi entsyymikäsittelyn avulla | |
| SU563146A1 (ru) | Способ консервировани пантов | |
| DE58908297D1 (de) | Verfahren zur Stabilisierung von biologisch aktiven Substanzen in immobilisierter Form. | |
| BE866718A (fr) | Nouveaux derives d'acides azolylalcane-carboxyliques, leur procede de preparation et leur application comme fongicides | |
| SU825617A1 (ru) | Способ получения 'сухих продуктов микробиологического синтеза | |
| SU1520097A1 (ru) | Способ получени молибдокофактора | |
| FR2331550A1 (fr) | Nouveaux derives d'acides vinylamino-benzoiques chlores, leur procede de preparation et leur application comme substances de croissance des vegetaux | |
| BE888890A (fr) | Derives nicotiniques de glucosamine, leur procede de preparation et compositions pharmaceutiques correspondantes | |
| RU94037133A (ru) | Способ консервирования пищевых продуктов |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |