NO985683D0 - Fragmenter av leptin (ob protein) - Google Patents

Fragmenter av leptin (ob protein)

Info

Publication number
NO985683D0
NO985683D0 NO985683A NO985683A NO985683D0 NO 985683 D0 NO985683 D0 NO 985683D0 NO 985683 A NO985683 A NO 985683A NO 985683 A NO985683 A NO 985683A NO 985683 D0 NO985683 D0 NO 985683D0
Authority
NO
Norway
Prior art keywords
leptin
fragments
protein
Prior art date
Application number
NO985683A
Other languages
English (en)
Norwegian (no)
Other versions
NO985683L (no
Inventor
Kamal A Al-Barazanji
Jonathan Robert Sanders Arch
Patrick Camilleri
William Arthur Neville
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9611775.9A external-priority patent/GB9611775D0/en
Priority claimed from GBGB9618540.0A external-priority patent/GB9618540D0/en
Priority claimed from GBGB9703493.8A external-priority patent/GB9703493D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO985683L publication Critical patent/NO985683L/no
Publication of NO985683D0 publication Critical patent/NO985683D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO985683A 1996-06-06 1998-12-04 Fragmenter av leptin (ob protein) NO985683D0 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9611775.9A GB9611775D0 (en) 1996-06-06 1996-06-06 Novel compounds
GBGB9618540.0A GB9618540D0 (en) 1996-09-05 1996-09-05 Novel compounds
GBGB9703493.8A GB9703493D0 (en) 1997-02-20 1997-02-20 Novel compounds
PCT/EP1997/002968 WO1997046585A2 (en) 1996-06-06 1997-06-04 Fragments of leptin (ob protein)

Publications (2)

Publication Number Publication Date
NO985683L NO985683L (no) 1998-12-04
NO985683D0 true NO985683D0 (no) 1998-12-04

Family

ID=27268305

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985683A NO985683D0 (no) 1996-06-06 1998-12-04 Fragmenter av leptin (ob protein)

Country Status (15)

Country Link
EP (1) EP0912609A2 (de)
JP (1) JP2000512137A (de)
KR (1) KR20000016402A (de)
CN (1) CN1221426A (de)
AR (1) AR008765A1 (de)
AU (1) AU3337297A (de)
BR (1) BR9709529A (de)
CA (1) CA2257240A1 (de)
CZ (1) CZ397898A3 (de)
IL (1) IL127153A0 (de)
NO (1) NO985683D0 (de)
NZ (1) NZ332879A (de)
PL (1) PL330361A1 (de)
TR (1) TR199802534T2 (de)
WO (1) WO1997046585A2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
CA2335107C (en) 1998-07-28 2010-01-19 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Leptin-mediated gene-induction
US7208572B2 (en) * 1998-08-21 2007-04-24 Albany Medical College Leptin-related peptides
US6777388B1 (en) 1998-08-21 2004-08-17 Clf Medical Technology Acceleration Program, Inc. Leptin-related peptides
US6420339B1 (en) 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
AU782230B2 (en) 1999-09-22 2005-07-14 Serono Genetics Institute S.A. Methods of screening for compounds that modulate the LSR-leptin interaction and their use in the prevention and treatment of obesity-related diseases
ATE300611T1 (de) 2000-05-22 2005-08-15 Vlaams Interuniv Inst Biotech Auf rezeptorgrundlage arbeitende screening- verfahren für protein wechselwirkungen
EP1444516B1 (de) 2001-10-22 2010-07-21 Amgen, Inc. Verwendung von leptin zur behandlung von lipoatrophie im menschen und verfahren zur bestimmmung einer prädisposition gegenüber der behandlung
DE602004012759T2 (de) 2003-09-08 2008-07-17 Laboratoires Serono S.A., Coinsins Behandlung von fibrosen
CN1961000B (zh) 2004-02-11 2011-05-04 安米林药品公司 具有可选择特性的杂合多肽
EP1812038A1 (de) 2004-11-18 2007-08-01 VIB vzw Fibronectin iii domäne als leptin-rezeptor-antagonisten
SG159551A1 (en) 2005-02-11 2010-03-30 Amylin Pharmaceuticals Inc Gip analog and hybrid polypeptides with selectable properties
US7629315B2 (en) 2005-03-09 2009-12-08 University Of Pittsburgh Of The Commonwealth System Of Higher Education Compositions for blocking the inhibitory effect of human CRP on human leptin
EP2330125A3 (de) 2005-08-11 2012-12-12 Amylin Pharmaceuticals, Inc. Hybridpolypeptide mit auswählbaren Eigenschaften
CA2617649A1 (en) 2005-08-11 2007-02-22 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
ES2319048B1 (es) * 2007-06-20 2010-02-10 Universitat De Les Illes Balears Uso de leptina en el tratamiento de alteraciones en los habitos alimentarios.
US8889622B2 (en) 2007-07-25 2014-11-18 Washington University Methods of inhibiting seizure in a subject
GB2451858A (en) * 2007-08-15 2009-02-18 Sergiy Konovchuk Methods of reducing body fat and treating obesity
US20110059969A1 (en) 2007-12-05 2011-03-10 Astrazeneca Ab Piperazines as anti-obesity agents
EP2234992B1 (de) 2007-12-05 2012-02-22 AstraZeneca AB Piperazinderivate und ihre verwendung als modulatoren des leptinrezeptors
KR20110015446A (ko) * 2008-06-04 2011-02-15 아스트라제네카 아베 렙틴 수용체 조절제 유사체로서의 신규한 피리딘 유도체
US20110275637A1 (en) * 2008-06-04 2011-11-10 Emma Chapman Piperazine derivatives and their use as leptin receptor modulators
US20120071401A1 (en) 2009-04-10 2012-03-22 Amylin Pharamaceuticals, Inc. Amylin agonist compounds for estrogen-deficient mammals
EP2569326B1 (de) * 2010-05-11 2016-08-10 The U.S.A. as represented by the Secretary, Department of Health and Human Services Peptidbasierter inhibitor des interleukin-10- oder der stat-3 aktivierung
WO2012050930A2 (en) 2010-09-28 2012-04-19 Amylin Pharmaceuticals, Inc Engineered polypeptides having enhanced duration of action
CN104829707B (zh) * 2015-05-06 2017-12-19 广东省生物资源应用研究所 一条cd环和e螺旋区突变的瘦素活性肽及其编码基因和应用
CN110183530A (zh) 2019-06-21 2019-08-30 深圳市亚辉龙生物科技股份有限公司 瘦素免疫原、杂交瘤细胞、单克隆抗体、多克隆抗体及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
CA2211656A1 (en) * 1995-01-31 1996-08-08 Margret B. Basinski Anti-obesity proteins
US5552523A (en) * 1995-01-31 1996-09-03 Eli Lilly And Company Anti-obesity proteins
AU4766596A (en) * 1995-01-31 1996-08-21 Eli Lilly And Company Ob gene product antibodies
AU5539596A (en) * 1995-04-06 1996-10-23 Amylin Pharmaceuticals, Inc. Anti-obesity agents
GB9509164D0 (en) * 1995-05-05 1995-06-28 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
TR199802534T2 (xx) 1999-03-22
CA2257240A1 (en) 1997-12-11
JP2000512137A (ja) 2000-09-19
NO985683L (no) 1998-12-04
NZ332879A (en) 2000-09-29
AR008765A1 (es) 2000-02-23
PL330361A1 (en) 1999-05-10
CN1221426A (zh) 1999-06-30
WO1997046585A3 (en) 1998-04-23
CZ397898A3 (cs) 1999-04-14
IL127153A0 (en) 1999-09-22
WO1997046585A2 (en) 1997-12-11
BR9709529A (pt) 1999-08-10
AU3337297A (en) 1998-01-05
KR20000016402A (ko) 2000-03-25
EP0912609A2 (de) 1999-05-06

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application