NO995590L - 20-Aryl-5<alfa>-pregnan-derivater - Google Patents

20-Aryl-5<alfa>-pregnan-derivater

Info

Publication number: NO995590L
Authority: NO; Norway
Prior art keywords: alkyl; alkoxy; hydroxy; halogen; independently hydrogen
Prior art date: 1997-05-16

Application number

NO995590A

Other languages

English (en)

Norwegian (no)

Other versions

NO995590D0 (no

Inventor

Johannes Antonius Jos Leemhuis

Jaap Van Der Louw

Marinus Bernard Groen

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-16

Filing date

1999-11-15

Publication date

2000-01-11

1999-11-15 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

1999-11-15 Publication of NO995590D0 publication Critical patent/NO995590D0/no

2000-01-11 Publication of NO995590L publication Critical patent/NO995590L/no

Links

125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 3
150000002367 halogens Chemical class 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
YYQGUWHFXVXQOO-GFCCVEGCSA-N 2-chloro-4-[[3-[(2R)-2-hydroxybutyl]-1-methyl-2-oxobenzimidazol-5-yl]amino]pyridine-3-carbonitrile Chemical compound ClC1=C(C#N)C(=CC=N1)NC1=CC2=C(N(C(N2C[C@@H](CC)O)=O)C)C=C1 YYQGUWHFXVXQOO-GFCCVEGCSA-N 0.000 abstract 1
239000004215 Carbon black (E152) Substances 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
230000003213 activating effect Effects 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000035558 fertility Effects 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
230000021121 meiosis Effects 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO995590A 1997-05-16 1999-11-15 20-Aryl-5<alfa>-pregnan-derivater NO995590L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97201474		1997-05-16
PCT/EP1998/002989 WO1998052965A1 (en)	1997-05-16	1998-05-11	20-ARALKYL-5α-PREGNANE DERIVATIVES

Publications (2)

Publication Number	Publication Date
NO995590D0 NO995590D0 (no)	1999-11-15
NO995590L true NO995590L (no)	2000-01-11

Family

ID=8228325

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO995590A NO995590L (no)	1997-05-16	1999-11-15	20-Aryl-5<alfa>-pregnan-derivater

Country Status (17)

Country	Link
US (1)	US6177420B1 (de)
EP (1)	EP0984980B1 (de)
JP (1)	JP2001526673A (de)
KR (1)	KR20010012643A (de)
CN (1)	CN1260802A (de)
AT (1)	ATE229032T1 (de)
AU (1)	AU726016B2 (de)
BR (1)	BR9808803A (de)
CA (1)	CA2289675A1 (de)
DE (1)	DE69809905T2 (de)
DK (1)	DK0984980T3 (de)
ES (1)	ES2189173T3 (de)
HU (1)	HUP0002331A3 (de)
NO (1)	NO995590L (de)
PL (1)	PL337008A1 (de)
TR (1)	TR199902793T2 (de)
WO (1)	WO1998052965A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2001526293A (ja) *	1997-12-18	2001-12-18	アクゾ・ノベル・エヌ・ベー	１７β−アリール（アリールメチル）オキシ（チオ）アルキル−アンドロスタン誘導体
WO1999058549A1 (en) *	1998-05-13	1999-11-18	Novo Nordisk A/S	Meiosis regulating compounds
IL140216A0 (en) *	1998-06-19	2002-02-10	Novo Nordisk As	Meiosis regulating compounds
US6552011B1 (en)	1999-03-02	2003-04-22	Akzo Nobel Nv	(Androst-5-en-17beta -yl)alkyl sulfoxides and sulfones and their use for control of fertility
EP1212345B1 (de) *	1999-04-06	2003-08-06	Akzo Nobel N.V.	Oral wirksame 7-alpha-alkyl androgene
EP1127890A1 (de)	2000-02-22	2001-08-29	Schering Aktiengesellschaft	Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose
US6988613B2 (en) *	2001-02-06	2006-01-24	Novo Nordisk A/S	Composition for IVF
WO2005020928A2 (en)	2003-08-29	2005-03-10	The Regents Of The University Of California	Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
JP2007517877A (ja)	2004-01-15	2007-07-05	ワーナー・チルコット・カンパニー・インコーポレーテッド	エストラジオールのジ−ステロイド型プロドラッグ
WO2005070950A1 (en)	2004-01-15	2005-08-04	Warner Chilcott Company, Inc.	Di-steroidal prodrugs of ethinyl estradiol
CN101218245B (zh)	2005-07-12	2011-08-17	沃纳奇尔科特有限责任公司	炔雌醇的3-酯前药
CA2643732C (en)	2006-02-27	2012-08-21	The Regents Of The University Of California	Oxysterol compounds and the hedgehog pathway
CN101951915A (zh)	2007-12-03	2011-01-19	加利福尼亚大学董事会	用于刺猬蛋白信号、骨诱导、抗脂肪形成和wnt信号的激活的氧固醇
CA2872751A1 (en)	2012-05-07	2013-11-14	The Regents Of The University Of California	Oxysterol analogue oxy133 induces osteogenesis and hedgehog signaling and inhibits adipogenesis
JP2016517888A (ja)	2013-05-02	2016-06-20	ザリージェンツオブザユニバーシティオブカリフォルニア	骨選択的骨形成のオキシステロール骨標的薬剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5716777A (en) *	1994-06-23	1998-02-10	Novo Nordisk A/S	Regulation of meiosis using sterols
HUP9800731A3 (en)	1995-03-06	2000-03-28	Novo Nordisk As	Stimulation of meiosis
CA2224866A1 (en)	1995-06-23	1997-01-09	Novo Nordisk A/S	Meiosis regulating compounds

1998
- 1998-05-11 WO PCT/EP1998/002989 patent/WO1998052965A1/en not_active Ceased
- 1998-05-11 HU HU0002331A patent/HUP0002331A3/hu unknown
- 1998-05-11 CN CN98806290A patent/CN1260802A/zh active Pending
- 1998-05-11 DE DE69809905T patent/DE69809905T2/de not_active Expired - Fee Related
- 1998-05-11 EP EP98924316A patent/EP0984980B1/de not_active Expired - Lifetime
- 1998-05-11 ES ES98924316T patent/ES2189173T3/es not_active Expired - Lifetime
- 1998-05-11 PL PL98337008A patent/PL337008A1/xx unknown
- 1998-05-11 BR BR9808803-3A patent/BR9808803A/pt not_active Application Discontinuation
- 1998-05-11 DK DK98924316T patent/DK0984980T3/da active
- 1998-05-11 TR TR1999/02793T patent/TR199902793T2/xx unknown
- 1998-05-11 JP JP54995898A patent/JP2001526673A/ja not_active Ceased
- 1998-05-11 AT AT98924316T patent/ATE229032T1/de not_active IP Right Cessation
- 1998-05-11 KR KR1019997010604A patent/KR20010012643A/ko not_active Withdrawn
- 1998-05-11 AU AU76549/98A patent/AU726016B2/en not_active Ceased
- 1998-05-11 US US09/423,743 patent/US6177420B1/en not_active Expired - Fee Related
- 1998-05-11 CA CA002289675A patent/CA2289675A1/en not_active Abandoned
1999
- 1999-11-15 NO NO995590A patent/NO995590L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
TR199902793T2 (xx)	2000-06-21
BR9808803A (pt)	2000-07-18
CN1260802A (zh)	2000-07-19
JP2001526673A (ja)	2001-12-18
KR20010012643A (ko)	2001-02-26
HUP0002331A3 (en)	2001-05-28
DK0984980T3 (da)	2003-03-17
EP0984980A1 (de)	2000-03-15
EP0984980B1 (de)	2002-12-04
PL337008A1 (en)	2000-07-31
ATE229032T1 (de)	2002-12-15
WO1998052965A1 (en)	1998-11-26
ES2189173T3 (es)	2003-07-01
NO995590D0 (no)	1999-11-15
HUP0002331A2 (hu)	2000-12-28
DE69809905T2 (de)	2003-08-28
AU7654998A (en)	1998-12-11
US6177420B1 (en)	2001-01-23
CA2289675A1 (en)	1998-11-26
AU726016B2 (en)	2000-10-26
DE69809905D1 (de)	2003-01-16

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Legal Events

Date	Code	Title	Description
2002-03-18	FC2A	Withdrawal, rejection or dismissal of laid open patent application