NO996178L - 4-aminopyrrol(3,2-d)pyrimidiner som neuropeptid y- reseptorantagonister - Google Patents

4-aminopyrrol(3,2-d)pyrimidiner som neuropeptid y- reseptorantagonister

Info

Publication number: NO996178L
Authority: NO; Norway
Prior art keywords: neuropeptide; aminopyrrole; pyrimidines; receptor antagonists; excess
Prior art date: 1997-08-05

Application number

NO996178A

Other languages

English (en)

Norwegian (no)

Other versions

NO996178D0 (no

Inventor

Robert Lee Dow

Marlys Hammond

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-05

Filing date

1999-12-14

Publication date

2000-02-14

1999-12-14 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

1999-12-14 Publication of NO996178D0 publication Critical patent/NO996178D0/no

2000-02-14 Publication of NO996178L publication Critical patent/NO996178L/no

Links

PLSDWRYNZIVQKX-BGKYVOMCSA-N (3S)-3-amino-4-[[(2S)-1-[[2-[[(2S)-1-[[2-[[(2S)-5-amino-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S,3R)-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Chemical compound CC[C@H](C)[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC2=CNC=N2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CC4=CNC=N4)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)N PLSDWRYNZIVQKX-BGKYVOMCSA-N 0.000 title 1
WAUGGYPDCQZJKK-UHFFFAOYSA-N 1h-pyrrol-3-amine Chemical compound NC=1C=CNC=1 WAUGGYPDCQZJKK-UHFFFAOYSA-N 0.000 title 1
102100024304 Protachykinin-1 Human genes 0.000 title 1
150000003230 pyrimidines Chemical class 0.000 title 1
239000002464 receptor antagonist Substances 0.000 title 1
229940044551 receptor antagonist Drugs 0.000 title 1
108010073085 tachykinin neuropeptide gamma Proteins 0.000 title 1
101710151321 Melanostatin Proteins 0.000 abstract 1
102400000064 Neuropeptide Y Human genes 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
URPYMXQQVHTUDU-OFGSCBOVSA-N nucleopeptide y Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 URPYMXQQVHTUDU-OFGSCBOVSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO996178A 1997-08-05 1999-12-14 4-aminopyrrol(3,2-d)pyrimidiner som neuropeptid y- reseptorantagonister NO996178L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5473497P	1997-08-05	1997-08-05
PCT/IB1998/001053 WO1999007703A1 (fr)	1997-08-05	1998-07-10	4-AMINOPYRROLE(3,2-d)PYRIMIDINES EN TANT QU'ANTAGONISTES DU RECEPTEUR DU NEUROPEPTIDE Y

Publications (2)

Publication Number	Publication Date
NO996178D0 NO996178D0 (no)	1999-12-14
NO996178L true NO996178L (no)	2000-02-14

Family

ID=21993163

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO996178A NO996178L (no)	1997-08-05	1999-12-14	4-aminopyrrol(3,2-d)pyrimidiner som neuropeptid y- reseptorantagonister

Country Status (32)

Country	Link
US (1)	US6187778B1 (fr)
EP (1)	EP1003744B1 (fr)
JP (1)	JP3711238B2 (fr)
KR (1)	KR20010022583A (fr)
CN (1)	CN1264381A (fr)
AP (1)	AP9801312A0 (fr)
AT (1)	ATE296825T1 (fr)
AU (1)	AU7927498A (fr)
BG (1)	BG104107A (fr)
BR (1)	BR9811844A (fr)
CA (1)	CA2293621C (fr)
CO (1)	CO4960634A1 (fr)
DE (1)	DE69830409T2 (fr)
EA (1)	EA200000098A1 (fr)
ES (1)	ES2241146T3 (fr)
GT (1)	GT199800114A (fr)
HR (1)	HRP980434A2 (fr)
HU (1)	HUP0002956A3 (fr)
ID (1)	ID24300A (fr)
IL (1)	IL133430A0 (fr)
IS (1)	IS5294A (fr)
MA (1)	MA24629A1 (fr)
NO (1)	NO996178L (fr)
OA (1)	OA11277A (fr)
PA (1)	PA8456601A1 (fr)
PE (1)	PE106199A1 (fr)
PL (1)	PL338575A1 (fr)
SA (1)	SA98190435A (fr)
TN (1)	TNSN98148A1 (fr)
TR (1)	TR200000333T2 (fr)
WO (1)	WO1999007703A1 (fr)
ZA (1)	ZA986968B (fr)

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EP1218381B1 (fr) *	1999-09-30	2006-12-06	Neurogen Corporation	PYRAZOLO¬1,5-a\|-1,5-PYRIMIDINES ET PYRAZOLO¬1,5-a\|-1,3,5-TRIAZINES AMINO SUBSTITUEES
WO2001047922A2 (fr) *	1999-12-24	2001-07-05	Aventis Pharma Limited	Azaindoles
GB0117396D0 (en)	2001-07-17	2001-09-05	Glaxo Group Ltd	Chemical compounds
GB0308208D0 (en)	2003-04-09	2003-05-14	Glaxo Group Ltd	Chemical compounds
MEP8409A (en)	2004-06-02	2011-12-20		Fused heterocyclic compound
CA2570693A1 (fr)	2004-06-17	2006-01-26	Wyeth	Procedes pour la preparation d'antagonistes du recepteur de la gonadoliberine
EP1758895A1 (fr)	2004-06-17	2007-03-07	Wyeth a Corporation of the State of Delaware	Antagonistes de récepteurs de l'hormone de libération de gonadotrophines
EP1797054A2 (fr) *	2004-08-02	2007-06-20	OSI Pharmaceuticals, Inc.	Composes a base de pyrrolopyrimidine a substitution arylamine inhibiteurs de kinases multiples
MY179032A (en)	2004-10-25	2020-10-26	Cancer Research Tech Ltd	Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors
KR20060087386A (ko) *	2005-01-28	2006-08-02	주식회사 대웅제약	신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물
WO2006080821A1 (fr) *	2005-01-28	2006-08-03	Daewoong Pharmaceutical Co., Ltd.	Nouveaux derives benzoimidazole et composition pharmaceutique les contenant
US7534796B2 (en)	2005-02-18	2009-05-19	Wyeth	Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
US7538113B2 (en)	2005-02-18	2009-05-26	Wyeth	4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7582634B2 (en)	2005-02-18	2009-09-01	Wyeth	7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
AU2006235200A1 (en) *	2005-04-15	2006-10-19	Regenertech Pty Limited	Use of Neuropeptide Y (NPY) and agonists and antagonists thereof for tissue regeneration
US7531542B2 (en)	2005-05-18	2009-05-12	Wyeth	Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor
US7582636B2 (en)	2005-05-26	2009-09-01	Wyeth	Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
US7994331B2 (en) *	2005-07-13	2011-08-09	Msd K.K.	Heterocycle-substituted benzimidazole derivative
UY29825A1 (es) *	2005-10-03	2007-05-31	Astrazeneca Ab	Derivados sustituidos de 3h-imidazol-(4,5 b (beta))piridina-2-il benzoatos y benzamidas, composiciones farmacéuticas que los contienen y aplicaciones
UY29823A1 (es) *	2005-10-03	2007-05-31	Astrazeneca Ab	Derivados sustituidos de 7-cloro-3h-imidazol-(4,5-b) piridina, composiciones farmacéuticas que los contienen, procesos para la preparación de los mismos y aplicaciones
WO2007067537A1 (fr) *	2005-12-07	2007-06-14	Osi Pharmaceuticals, Inc.	Composés inhibant les pyrrolopyridine kinases
WO2007072017A2 (fr) *	2005-12-22	2007-06-28	The Institute Of Cancer Research	Inhibiteurs d'enzymes
JP2009528989A (ja)	2006-02-17	2009-08-13	ファイザー・リミテッド	Ｔｌｒ７変調剤としての３−デアザプリン誘導体
WO2007125321A2 (fr)	2006-04-25	2007-11-08	Astex Therapeutics Limited	Composés pharmaceutiques
PL2054405T3 (pl) *	2006-07-11	2014-03-31	Dae Woong Pharma	Nowe pochodne biarylobenzimidazolu i zawierająca je kompozycja farmaceutyczna
KR101134239B1 (ko)	2006-07-11	2012-04-10	주식회사 대웅제약	신규한 바이아릴 벤조이미다졸 유도체 및 이를 함유하는 약학 조성물
CL2007002617A1 (es)	2006-09-11	2008-05-16	Sanofi Aventis	Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto.
WO2008121064A1 (fr) *	2007-03-30	2008-10-09	Astrazeneca Ab	Nouveaux composés d'imidazo[4,5-b]pyridine-6-halo-7-aryl/heteroaryle 705
DE102007027800A1 (de)	2007-06-16	2008-12-18	Bayer Healthcare Ag	Substituierte bicyclische Heteroaryl-Verbindungen und ihre Verwendung
AU2008309383B2 (en)	2007-10-11	2012-04-19	Astrazeneca Ab	Pyrrolo [2, 3 -D] pyrimidin derivatives as protein kinase B inhibitors
WO2009098715A2 (fr)	2008-01-11	2009-08-13	Natco Pharma Limited	Nouveaux dérivés de pyrazolo [3, 4 -d] pyrimidine en tant qu’agents anticancéreux
BR112013025410A2 (pt)	2011-04-01	2016-12-20	Astrazeneca Ab	tratamento terapêutico
CA2856646C (fr)	2011-11-30	2020-01-14	Astrazeneca Ab	Traitement combine du cancer
AU2013204533B2 (en)	2012-04-17	2017-02-02	Astrazeneca Ab	Crystalline forms
CA3120866A1 (fr) *	2018-11-30	2020-06-04	Nimbus Lakshmi, Inc.	Inhibiteurs de tyk2 et leurs utilisations

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DE2818676A1 (de) *	1978-04-27	1979-11-08	Troponwerke Gmbh & Co Kg	Substituierte 5,6-dimethylpyrrolo 2,3-d pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB9022644D0 (en) *	1990-10-18	1990-11-28	Ici Plc	Heterocyclic compounds
US5877178A (en) *	1991-04-08	1999-03-02	Duquesne University Of The Holy Ghost	Pyrimidine derivatives and methods of making and using these derivatives
US5235053A (en) *	1992-06-22	1993-08-10	Eli Lilly And Company	Process for the synthesis of 4-hydroxy-5-halopyrrold[2,3-d]pyrimidine intermediates
US5284971A (en)	1992-07-16	1994-02-08	Syntex (U.S.A.) Inc.	4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents
ES2108855T3 (es)	1992-07-21	1998-01-01	Ciba Geigy Ag	Derivados de acido oxamico como agentes hipocolesteremicos.
EP0682027B1 (fr) *	1994-05-03	1997-10-15	Novartis AG	Dérivés de la pyrrolopyrimidine avec une activité anti-proliférative
DK0783505T3 (da) *	1994-09-29	2001-07-02	Novartis Ag	Pyrrolo[2,3-d]pyrimidiner og deres anvendelse
US6562862B1 (en)	1994-10-20	2003-05-13	Eli Lilly And Company	Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
BR9509610A (pt)	1994-11-07	1997-10-28	Pfizer	Ligandos específicos de neuropeptideo Y1
US5644057A (en) *	1995-05-12	1997-07-01	Neurogen Corporation	Deazapurine derivatives; a new class of CRF1 specific ligands
EP0759441A3 (fr)	1995-06-30	1999-06-30	Eli Lilly And Company	Procédés de traitement des pathologies associées aux peptides neuropeptide Y
CA2242579A1 (fr)	1996-01-09	1997-07-17	Eli Lilly And Company	Antagonistes benzimidazolyles du recepteur du neuropeptide y

1998
- 1998-07-10 US US09/380,901 patent/US6187778B1/en not_active Expired - Fee Related
- 1998-07-10 TR TR2000/00333T patent/TR200000333T2/xx unknown
- 1998-07-10 AU AU79274/98A patent/AU7927498A/en not_active Abandoned
- 1998-07-10 BR BR9811844-7A patent/BR9811844A/pt not_active Application Discontinuation
- 1998-07-10 PL PL98338575A patent/PL338575A1/xx unknown
- 1998-07-10 ID IDW20000021A patent/ID24300A/id unknown
- 1998-07-10 CN CN98807398A patent/CN1264381A/zh active Pending
- 1998-07-10 ES ES98929573T patent/ES2241146T3/es not_active Expired - Lifetime
- 1998-07-10 JP JP2000506207A patent/JP3711238B2/ja not_active Expired - Fee Related
- 1998-07-10 CA CA002293621A patent/CA2293621C/fr not_active Expired - Fee Related
- 1998-07-10 WO PCT/IB1998/001053 patent/WO1999007703A1/fr not_active Ceased
- 1998-07-10 IL IL13343098A patent/IL133430A0/xx unknown
- 1998-07-10 EP EP98929573A patent/EP1003744B1/fr not_active Expired - Lifetime
- 1998-07-10 AT AT98929573T patent/ATE296825T1/de not_active IP Right Cessation
- 1998-07-10 EA EA200000098A patent/EA200000098A1/ru unknown
- 1998-07-10 DE DE69830409T patent/DE69830409T2/de not_active Expired - Fee Related
- 1998-07-10 HU HU0002956A patent/HUP0002956A3/hu unknown
- 1998-07-10 KR KR1020007001174A patent/KR20010022583A/ko not_active Ceased
- 1998-07-27 GT GT199800114A patent/GT199800114A/es unknown
- 1998-07-30 PE PE1998000678A patent/PE106199A1/es not_active Application Discontinuation
- 1998-07-30 AP APAP/P/1998/001312A patent/AP9801312A0/en unknown
- 1998-08-03 PA PA19988456601A patent/PA8456601A1/es unknown
- 1998-08-04 TN TNTNSN98148A patent/TNSN98148A1/fr unknown
- 1998-08-04 MA MA25203A patent/MA24629A1/fr unknown
- 1998-08-04 HR HR60/054,734A patent/HRP980434A2/hr not_active Application Discontinuation
- 1998-08-04 ZA ZA9806968A patent/ZA986968B/xx unknown
- 1998-08-05 CO CO98044925A patent/CO4960634A1/es unknown
- 1998-08-19 SA SA98190435A patent/SA98190435A/ar unknown
1999
- 1999-12-10 IS IS5294A patent/IS5294A/is unknown
- 1999-12-14 NO NO996178A patent/NO996178L/no not_active Application Discontinuation
2000
- 2000-01-14 OA OA1200000007A patent/OA11277A/en unknown
- 2000-01-26 BG BG104107A patent/BG104107A/bg unknown

Also Published As

Publication number	Publication date
ES2241146T3 (es)	2005-10-16
HRP980434A2 (en)	1999-04-30
GT199800114A (es)	2000-01-18
CA2293621C (fr)	2003-12-30
MA24629A1 (fr)	1999-04-01
KR20010022583A (ko)	2001-03-26
HUP0002956A3 (en)	2002-01-28
SA98190435A (ar)	2005-12-03
JP3711238B2 (ja)	2005-11-02
IL133430A0 (en)	2001-04-30
CA2293621A1 (fr)	1999-02-18
HUP0002956A2 (hu)	2001-08-28
EP1003744B1 (fr)	2005-06-01
PA8456601A1 (es)	2000-05-24
CO4960634A1 (es)	2000-09-25
DE69830409T2 (de)	2006-01-26
OA11277A (en)	2003-07-29
PL338575A1 (en)	2000-11-06
DE69830409D1 (de)	2005-07-07
TR200000333T2 (tr)	2000-05-22
AU7927498A (en)	1999-03-01
WO1999007703A1 (fr)	1999-02-18
ID24300A (id)	2000-07-13
CN1264381A (zh)	2000-08-23
TNSN98148A1 (fr)	2005-03-15
EA200000098A1 (ru)	2000-08-28
US6187778B1 (en)	2001-02-13
IS5294A (is)	1999-12-10
ZA986968B (en)	2000-02-04
ATE296825T1 (de)	2005-06-15
BR9811844A (pt)	2000-08-08
PE106199A1 (es)	1999-11-02
BG104107A (bg)	2000-08-31
JP2001512729A (ja)	2001-08-28
AP9801312A0 (en)	2000-01-30
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