TR200000333T2 - Y alıcı antagonistleri olarak 4-aminopirol (3,2-d) pirimidinler. - Google Patents

Y alıcı antagonistleri olarak 4-aminopirol (3,2-d) pirimidinler.

Info

Publication number
TR200000333T2
TR200000333T2 TR2000/00333T TR200000333T TR200000333T2 TR 200000333 T2 TR200000333 T2 TR 200000333T2 TR 2000/00333 T TR2000/00333 T TR 2000/00333T TR 200000333 T TR200000333 T TR 200000333T TR 200000333 T2 TR200000333 T2 TR 200000333T2
Authority
TR
Turkey
Prior art keywords
aminopyrol
pyrimidines
receptor antagonists
neuropeptide
excess
Prior art date
Application number
TR2000/00333T
Other languages
English (en)
Inventor
Lee Dow Robert
Hammond Marlys
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200000333T2 publication Critical patent/TR200000333T2/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Nöropeptid Y'nin fazlaligiyla iliskilendirilen kosullarin tedavisi için formül (I) bilesimleri
TR2000/00333T 1997-08-05 1998-07-10 Y alıcı antagonistleri olarak 4-aminopirol (3,2-d) pirimidinler. TR200000333T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5473497P 1997-08-05 1997-08-05

Publications (1)

Publication Number Publication Date
TR200000333T2 true TR200000333T2 (tr) 2000-05-22

Family

ID=21993163

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/00333T TR200000333T2 (tr) 1997-08-05 1998-07-10 Y alıcı antagonistleri olarak 4-aminopirol (3,2-d) pirimidinler.

Country Status (32)

Country Link
US (1) US6187778B1 (tr)
EP (1) EP1003744B1 (tr)
JP (1) JP3711238B2 (tr)
KR (1) KR20010022583A (tr)
CN (1) CN1264381A (tr)
AP (1) AP9801312A0 (tr)
AT (1) ATE296825T1 (tr)
AU (1) AU7927498A (tr)
BG (1) BG104107A (tr)
BR (1) BR9811844A (tr)
CA (1) CA2293621C (tr)
CO (1) CO4960634A1 (tr)
DE (1) DE69830409T2 (tr)
EA (1) EA200000098A1 (tr)
ES (1) ES2241146T3 (tr)
GT (1) GT199800114A (tr)
HR (1) HRP980434A2 (tr)
HU (1) HUP0002956A3 (tr)
ID (1) ID24300A (tr)
IL (1) IL133430A0 (tr)
IS (1) IS5294A (tr)
MA (1) MA24629A1 (tr)
NO (1) NO996178L (tr)
OA (1) OA11277A (tr)
PA (1) PA8456601A1 (tr)
PE (1) PE106199A1 (tr)
PL (1) PL338575A1 (tr)
SA (1) SA98190435A (tr)
TN (1) TNSN98148A1 (tr)
TR (1) TR200000333T2 (tr)
WO (1) WO1999007703A1 (tr)
ZA (1) ZA986968B (tr)

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WO2006009734A1 (en) 2004-06-17 2006-01-26 Wyeth Gonadotropin releasing hormone receptor antagonists
WO2006009736A1 (en) 2004-06-17 2006-01-26 Wyeth Processes for preparing gonadotropin releasing hormone receptor antagonists
US7465726B2 (en) * 2004-08-02 2008-12-16 Osi Pharmaceuticals, Inc. Substituted pyrrolo[2.3-B]pyridines
MY179032A (en) 2004-10-25 2020-10-26 Cancer Research Tech Ltd Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors
AU2006209117B2 (en) * 2005-01-28 2009-12-10 Daewoong Pharmaceutical Co., Ltd. Novel benzoimidazole derivatives and pharmaceutical composition comprising the same
KR20060087386A (ko) * 2005-01-28 2006-08-02 주식회사 대웅제약 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물
US7534796B2 (en) 2005-02-18 2009-05-19 Wyeth Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
US7538113B2 (en) 2005-02-18 2009-05-26 Wyeth 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7582634B2 (en) 2005-02-18 2009-09-01 Wyeth 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
WO2006108218A1 (en) * 2005-04-15 2006-10-19 Regenertech Pty Limited Use of neuropeptide y (npy) and agonists and antagonists thereof for tissue regeneration
US7531542B2 (en) 2005-05-18 2009-05-12 Wyeth Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor
US7582636B2 (en) 2005-05-26 2009-09-01 Wyeth Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
CA2614544C (en) * 2005-07-13 2013-09-10 Banyu Pharmaceutical Co., Ltd. Heterocycle-substituted benzimidazole derivative
AR057525A1 (es) * 2005-10-03 2007-12-05 Astrazeneca Ab Compuestos inhibidores selectivos de gsk3 y un proceso para su preparacion
UY29825A1 (es) * 2005-10-03 2007-05-31 Astrazeneca Ab Derivados sustituidos de 3h-imidazol-(4,5 b (beta))piridina-2-il benzoatos y benzamidas, composiciones farmacéuticas que los contienen y aplicaciones
WO2007067537A1 (en) * 2005-12-07 2007-06-14 Osi Pharmaceuticals, Inc. Pyrrolopyridine kinase inhibiting compounds
EP1963315B1 (en) * 2005-12-22 2014-10-08 Cancer Research Technology Limited Enzyme inhibitors
JP2009528989A (ja) 2006-02-17 2009-08-13 ファイザー・リミテッド Tlr7変調剤としての3−デアザプリン誘導体
JP5606734B2 (ja) 2006-04-25 2014-10-15 アステックス、セラピューティックス、リミテッド 医薬化合物
KR101134239B1 (ko) 2006-07-11 2012-04-10 주식회사 대웅제약 신규한 바이아릴 벤조이미다졸 유도체 및 이를 함유하는 약학 조성물
CN101490037B (zh) * 2006-07-11 2013-06-12 大熊制药株式会社 联芳基苯并咪唑衍生物以及包含该衍生物的药物组合物
CL2007002617A1 (es) 2006-09-11 2008-05-16 Sanofi Aventis Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto.
WO2008121064A1 (en) * 2007-03-30 2008-10-09 Astrazeneca Ab New imidazo[4,5-b]pyridine-6-halo-7-aryl/heteroaryl compounds 705
DE102007027800A1 (de) 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituierte bicyclische Heteroaryl-Verbindungen und ihre Verwendung
BRPI0818533B8 (pt) 2007-10-11 2021-05-25 Astrazeneca Ab composto, composição farmacêutica, uso de um composto, e, processo para a preparação de um composto
WO2009098715A2 (en) 2008-01-11 2009-08-13 Natco Pharma Limited Novel pyrazolo [3, 4 -d] pyrimidine derivatives as anti -cancer agents
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PT2785349T (pt) 2011-11-30 2019-12-11 Astrazeneca Ab Tratamento combinado de cancro
AU2013204533B2 (en) 2012-04-17 2017-02-02 Astrazeneca Ab Crystalline forms
CN113271938A (zh) * 2018-11-30 2021-08-17 林伯士拉克许米公司 Tyk2抑制剂和其用途

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DE2818676A1 (de) * 1978-04-27 1979-11-08 Troponwerke Gmbh & Co Kg Substituierte 5,6-dimethylpyrrolo 2,3-d pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB9022644D0 (en) * 1990-10-18 1990-11-28 Ici Plc Heterocyclic compounds
US5877178A (en) * 1991-04-08 1999-03-02 Duquesne University Of The Holy Ghost Pyrimidine derivatives and methods of making and using these derivatives
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Also Published As

Publication number Publication date
NO996178L (no) 2000-02-14
CN1264381A (zh) 2000-08-23
US6187778B1 (en) 2001-02-13
PE106199A1 (es) 1999-11-02
HUP0002956A2 (hu) 2001-08-28
JP3711238B2 (ja) 2005-11-02
DE69830409D1 (de) 2005-07-07
ZA986968B (en) 2000-02-04
BR9811844A (pt) 2000-08-08
JP2001512729A (ja) 2001-08-28
SA98190435A (ar) 2005-12-03
HRP980434A2 (en) 1999-04-30
HUP0002956A3 (en) 2002-01-28
WO1999007703A1 (en) 1999-02-18
ATE296825T1 (de) 2005-06-15
CA2293621A1 (en) 1999-02-18
PA8456601A1 (es) 2000-05-24
GT199800114A (es) 2000-01-18
TNSN98148A1 (fr) 2005-03-15
ES2241146T3 (es) 2005-10-16
EP1003744B1 (en) 2005-06-01
CA2293621C (en) 2003-12-30
AU7927498A (en) 1999-03-01
BG104107A (bg) 2000-08-31
IL133430A0 (en) 2001-04-30
PL338575A1 (en) 2000-11-06
EP1003744A1 (en) 2000-05-31
EA200000098A1 (ru) 2000-08-28
MA24629A1 (fr) 1999-04-01
CO4960634A1 (es) 2000-09-25
DE69830409T2 (de) 2006-01-26
IS5294A (is) 1999-12-10
OA11277A (en) 2003-07-29
AP9801312A0 (en) 2000-01-30
KR20010022583A (ko) 2001-03-26
ID24300A (id) 2000-07-13
NO996178D0 (no) 1999-12-14

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