OA01178A - Procédé de préparation de 1,1-dioxydes de la sulfamyl-3,4 dihydro-1,2,4, benzothiadiazine. - Google Patents
Procédé de préparation de 1,1-dioxydes de la sulfamyl-3,4 dihydro-1,2,4, benzothiadiazine.Info
- Publication number
- OA01178A OA01178A OA51359A OA51359A OA01178A OA 01178 A OA01178 A OA 01178A OA 51359 A OA51359 A OA 51359A OA 51359 A OA51359 A OA 51359A OA 01178 A OA01178 A OA 01178A
- Authority
- OA
- OAPI
- Prior art keywords
- benzothiadiazine
- sulfamyl
- dioxides
- dihydro
- preparing
- Prior art date
Links
- HAVZTGSQJIEKPI-UHFFFAOYSA-N benzothiadiazine Chemical compound C1=CC=C2C=NNSC2=C1 HAVZTGSQJIEKPI-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
- C07D285/26—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals
- C07D285/28—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
- C07D285/26—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals
- C07D285/30—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals with hydrocarbon radicals, substituted by hetero atoms, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71845258A | 1958-03-03 | 1958-03-03 | |
| US72724258A | 1958-04-09 | 1958-04-09 | |
| US74058258A | 1958-06-09 | 1958-06-09 | |
| US75162058A | 1958-07-29 | 1958-07-29 | |
| US76448258A | 1958-09-29 | 1958-09-29 | |
| DEC0028409 | 1959-02-27 | ||
| DEC0028408 | 1959-02-27 | ||
| DEC0024178 | 1959-02-27 | ||
| DEC0024176 | 1959-02-27 | ||
| DEC0024177 | 1959-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA01178A true OA01178A (fr) | 1969-01-25 |
Family
ID=27579177
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA51359A OA01178A (fr) | 1958-03-03 | 1964-12-31 | Procédé de préparation de 1,1-dioxydes de la sulfamyl-3,4 dihydro-1,2,4, benzothiadiazine. |
| OA52080A OA03826A (fr) | 1958-03-03 | 1965-06-29 | Procédé de préparation d'un composé hétérocyclique nouveau. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA52080A OA03826A (fr) | 1958-03-03 | 1965-06-29 | Procédé de préparation d'un composé hétérocyclique nouveau. |
Country Status (6)
| Country | Link |
|---|---|
| CH (4) | CH387642A (fr) |
| DE (4) | DE1445574A1 (fr) |
| FR (2) | FR1217929A (fr) |
| GB (1) | GB861367A (fr) |
| MY (1) | MY6200051A (fr) |
| OA (2) | OA01178A (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3200117A (en) * | 1962-10-03 | 1965-08-10 | Hoffmann La Roche | Derivatives of 1, 2, 4-benzothiadiazine-7-sulfonamide-1, 1-dioxide |
| DE2642140C2 (de) * | 1976-09-20 | 1982-10-28 | Degussa Ag, 6000 Frankfurt | Verfahren zur Herstellung von Benzoylcyanid |
| DE8700284U1 (de) * | 1987-01-07 | 1987-04-30 | Ernst Reiner GmbH & Co KG, 7743 Furtwangen | Post-Datumstempel |
| RU2214405C2 (ru) * | 1998-02-18 | 2003-10-20 | НьюроСёрч А/С | Новые соединения и их применение в качестве положительных модуляторов амра-рецепторов |
| US6943159B1 (en) | 1998-02-18 | 2005-09-13 | Neurosearch A/S | Compounds and their use as positive AMPA receptor modulators |
| US6982251B2 (en) | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| KR20070120617A (ko) | 2001-01-26 | 2007-12-24 | 쉐링 코포레이션 | 치환된 아제티딘온 화합물을 포함하는 약제학적 조성물 |
| US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| IL156445A0 (en) | 2001-01-26 | 2004-01-04 | Schering Corp | Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications |
| US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| EP1429756B1 (fr) | 2001-09-21 | 2006-11-22 | Schering Corporation | Methodes et combinaisons therapeutiques utiles pour le traitement du xanthome effectue avec des inhibiteurs d'absorption du sterol |
| US7056906B2 (en) | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
| EA200500234A1 (ru) | 2002-08-19 | 2005-08-25 | Пфайзер Продактс Инк. | Комбинированная терапия гиперпролиферативных болезней |
| CA2504916A1 (fr) | 2002-11-06 | 2004-05-27 | Schering Corporation | Inhibiteurs d'absorption de cholesterol pour le traitement de troubles auto-immuns |
| WO2004081004A1 (fr) | 2003-03-07 | 2004-09-23 | Schering Corporation | Composes d'azetidinone substitues, formulations et utilisations de ceux-ci pour traiter l'hypercholesterolemie |
| WO2004081002A1 (fr) | 2003-03-07 | 2004-09-23 | Schering Corporation | Composes d'azetidinone substitues, leurs formulations et utilisations en vue du traitement de l'hypercholesterolemie |
| DE602004018617D1 (de) | 2003-03-07 | 2009-02-05 | Schering Corp | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| ATE547394T1 (de) | 2006-12-01 | 2012-03-15 | Bristol Myers Squibb Co | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| WO2008151257A2 (fr) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonistes de guanylase cyclase utiles pour le traitement de troubles gastro-intestinaux, d'inflammation, de cancer et d'autres troubles |
| ES2627848T3 (es) | 2008-06-04 | 2017-07-31 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| EP2968439A2 (fr) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Compositions utiles pour le traitement de troubles gastro-intestinaux |
| CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
| PL3004138T3 (pl) | 2013-06-05 | 2024-07-29 | Bausch Health Ireland Limited | Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie |
| WO2016055901A1 (fr) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Composés d'amide substitué |
| WO2020150473A2 (fr) | 2019-01-18 | 2020-07-23 | Dogma Therapeutics, Inc. | Inhibiteurs de pcsk9 et leurs procédés d'utilisation |
-
1958
- 1958-12-16 FR FR781736A patent/FR1217929A/fr not_active Expired
-
1959
- 1959-02-19 CH CH18463A patent/CH387642A/de unknown
- 1959-02-19 CH CH18163A patent/CH377365A/de unknown
- 1959-02-19 CH CH6978359A patent/CH371454A/de unknown
- 1959-02-19 CH CH18063A patent/CH376514A/de unknown
- 1959-02-27 DE DE19591445574 patent/DE1445574A1/de active Pending
- 1959-02-27 DE DEC18496A patent/DE1112079B/de active Pending
- 1959-02-27 DE DE19591445007 patent/DE1445007A1/de active Pending
- 1959-02-27 DE DE19591445005 patent/DE1445005A1/de active Pending
- 1959-03-02 GB GB7209/59A patent/GB861367A/en not_active Expired
- 1959-03-03 FR FR788246A patent/FR1264468A/fr not_active Expired
-
1962
- 1962-12-30 MY MY51/62A patent/MY6200051A/xx unknown
-
1964
- 1964-12-31 OA OA51359A patent/OA01178A/fr unknown
-
1965
- 1965-06-29 OA OA52080A patent/OA03826A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1445007A1 (de) | 1968-10-24 |
| CH387642A (de) | 1965-02-15 |
| CH376514A (de) | 1964-04-15 |
| MY6200051A (en) | 1962-12-31 |
| DE1112079B (de) | 1961-08-03 |
| FR1264468A (fr) | 1961-06-23 |
| DE1445005A1 (de) | 1968-10-24 |
| DE1445006A1 (de) | 1968-10-24 |
| CH377365A (de) | 1964-05-15 |
| DE1445008A1 (de) | 1968-10-24 |
| CH371454A (de) | 1963-08-31 |
| DE1445006B2 (fr) | 1975-05-07 |
| DE1445574A1 (de) | 1969-01-16 |
| GB861367A (en) | 1961-02-22 |
| OA03826A (fr) | 1971-12-24 |
| FR1217929A (fr) | 1960-05-06 |
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