OA11241A - Tartrate salt of a substituted dipeptide as growthhormone secretagogue - Google Patents

Tartrate salt of a substituted dipeptide as growthhormone secretagogue Download PDF

Info

Publication number: OA11241A
Authority: OA; OAPI
Prior art keywords: compound; formula; tartaric acid; sait; manufacture
Prior art date: 1997-06-25

Application number

OA9900299A

Other languages

English (en)

Inventor

Philip Albert Carpino

Paul Andrew Dasilva-Jardine

Bruce Allen Lefker

Jerry Anthony Murry

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-25

Filing date

1999-12-21

Publication date

2003-05-26

1999-12-21 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2003-05-26 Publication of OA11241A publication Critical patent/OA11241A/en

Links

102100033367 Appetite-regulating hormone Human genes 0.000 title abstract description 10
239000003324 growth hormone secretagogue Substances 0.000 title abstract description 7
101710111255 Appetite-regulating hormone Proteins 0.000 title abstract description 5
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150000003892 tartrate salts Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 claims abstract description 163
102000018997 Growth Hormone Human genes 0.000 claims abstract description 83
239000000122 growth hormone Substances 0.000 claims abstract description 83
108010051696 Growth Hormone Proteins 0.000 claims abstract description 82
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DNXHEGUUPJUMQT-UHFFFAOYSA-N (+)-estrone Natural products OC1=CC=C2C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 DNXHEGUUPJUMQT-UHFFFAOYSA-N 0.000 claims abstract description 3
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- C07—ORGANIC CHEMISTRY
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Diabetes (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
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Orthopedic Medicine & Surgery (AREA)
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Obesity (AREA)
Immunology (AREA)
Crystallography & Structural Chemistry (AREA)
Neurology (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
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OA9900299A 1997-06-25 1999-12-21 Tartrate salt of a substituted dipeptide as growthhormone secretagogue OA11241A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5072397P	1997-06-25	1997-06-25

Publications (1)

Publication Number	Publication Date
OA11241A true OA11241A (en)	2003-05-26

Family

ID=21966996

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA9900299A OA11241A (en)	1997-06-25	1999-12-21	Tartrate salt of a substituted dipeptide as growthhormone secretagogue

Country Status (40)

Country	Link
US (2)	US6248717B1 (is)
EP (1)	EP0989993B1 (is)
JP (1)	JP3414759B2 (is)
KR (1)	KR100339936B1 (is)
CN (2)	CN1524857A (is)
AP (1)	AP1043A (is)
AR (1)	AR012255A1 (is)
AT (1)	ATE388163T1 (is)
AU (1)	AU744775B2 (is)
BG (1)	BG104024A (is)
BR (1)	BR9810623B1 (is)
CA (1)	CA2294422C (is)
CO (1)	CO4810383A1 (is)
DE (1)	DE69839211T2 (is)
DK (1)	DK0989993T3 (is)
DZ (1)	DZ2538A1 (is)
EA (1)	EA002643B1 (is)
ES (1)	ES2301196T3 (is)
GT (1)	GT199800085A (is)
HR (1)	HRP980362A2 (is)
HU (1)	HUP0002664A3 (is)
ID (1)	ID23188A (is)
IL (1)	IL132810A0 (is)
IS (1)	IS5276A (is)
MA (1)	MA26516A1 (is)
NO (1)	NO996469L (is)
NZ (1)	NZ500658A (is)
OA (1)	OA11241A (is)
PA (1)	PA8453401A1 (is)
PE (1)	PE97599A1 (is)
PL (1)	PL337654A1 (is)
PT (1)	PT989993E (is)
SK (1)	SK177299A3 (is)
TN (1)	TNSN98111A1 (is)
TR (1)	TR199903261T2 (is)
TW (1)	TWI221153B (is)
UA (1)	UA53716C2 (is)
UY (1)	UY25059A1 (is)
WO (1)	WO1998058948A1 (is)
ZA (1)	ZA985541B (is)

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UA53716C2 (uk)	1997-06-25	2003-02-17	Пфайзер Продактс Інк.	Тартратна сіль заміщеного дипептиду, спосіб її одержання, проміжні сполуки та спосіб їх одержання, фармацевтична композиція (варіанти), спосіб підвищення рівнів ендогенного гормону росту та спосіб лікування або профілактики захворювань (варіанти)
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US6518292B1 (en)	1999-03-12	2003-02-11	Bristol-Myers Squibb Co.	Heterocyclic aromatic compounds usefuls as growth hormone secretagogues
US6525203B1 (en)	1999-03-12	2003-02-25	Bristol-Myers Squibb Company	Heterocyclic aromatic compounds useful as growth hormone secretagogues
US20020013327A1 (en) *	2000-04-18	2002-01-31	Lee Andrew G.	Compositions and methods for treating female sexual dysfunction
CA2408486A1 (en)	2000-05-11	2001-11-15	Bristol-Myers Squibb Company	Tetrahydroisoquinoline analogs useful as growth hormone secretagogues
CA2410597A1 (en)	2000-05-30	2001-12-06	Merck & Co., Inc.	Melanocortin receptor agonists
DE60140285D1 (de) *	2000-05-31	2009-12-10	Pfizer Prod Inc	Verwendung von Wachstumshormonsekretagoga zur Förderung der Beweglichkeit des Verdauungstrakts
IL143690A0 (en) *	2000-06-19	2002-04-21	Pfizer Prod Inc	The use of growth hormone secretagogues to treat systemic lupus erythematosus and inflammatory bowel disease
IL143942A0 (en) *	2000-06-29	2002-04-21	Pfizer Prod Inc	Use of growth hormone secretagogues for treatment of physical performance decline
EP1181933A3 (en) *	2000-06-29	2002-04-10	Pfizer Products Inc.	Use of growth hormone secretagogues for stimulating or increasing appetite
MXPA03001771A (es) *	2000-08-30	2003-06-04	Pfizer Prod Inc	Formulaciones de liberacion sostenida para secretagogos de hormona del crecimiento.
IL145106A0 (en) *	2000-08-30	2002-06-30	Pfizer Prod Inc	Intermittent administration of a geowth hormone secretagogue
IL145540A0 (en) *	2000-09-28	2002-06-30	Pfizer Prod Inc	Use of growth hormone secretagogues in conjunction with physical exercise
BR0114630A (pt) *	2000-10-13	2003-07-01	Lilly Co Eli	Secretagogos de hormÈnio do crescimento
CA2372450A1 (en) *	2001-05-10	2001-09-19	Pharmaceutical Partners Of Canada Inc.	Liquid injectable formulation of disodium pamidronate
US7125840B2 (en)	2001-10-09	2006-10-24	Eli Lilly And Company	Substituted dipeptides as growth hormone secretagogues
WO2003041641A2 (en)	2001-11-09	2003-05-22	Bristol-Myers Squibb Company	Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity
EP1497316B1 (en)	2002-04-09	2006-07-05	Eli Lilly And Company	Growth hormone secretagogues
US7476653B2 (en)	2003-06-18	2009-01-13	Tranzyme Pharma, Inc.	Macrocyclic modulators of the ghrelin receptor
WO2005027913A1 (en) *	2003-09-19	2005-03-31	Pfizer Products Inc.	Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a growth hormone secretagogue
EP1789409A4 (en) *	2004-04-02	2010-09-08	Elixir Pharmaceuticals Inc	SULPHONAMIDES AND ITS USES
KR100641571B1 (ko) *	2005-01-05	2006-10-31	주식회사 팬택앤큐리텔	이동통신 단말기에서의 클럭 발생 장치
CU23558A1 (es)	2006-02-28	2010-07-20	Ct Ingenieria Genetica Biotech	Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
EP2644618B1 (en)	2007-02-09	2016-08-17	Ocera Therapeutics, Inc.	tether intermediates for the synthesis of macrocyclic ghrelin receptor modulators
US8377863B2 (en)	2007-05-29	2013-02-19	Unigene Laboratories Inc.	Peptide pharmaceutical for oral delivery
JP2014519520A (ja) *	2011-06-16	2014-08-14	ロンザ・リミテッド	ペプチドの抽出方法および液相ペプチド合成におけるその使用
CA2856030A1 (en) *	2011-11-16	2013-05-23	Duke University	Bisphosphonate compositions and methods for treating and/or reducing cardiac dysfunction
US9119832B2 (en)	2014-02-05	2015-09-01	The Regents Of The University Of California	Methods of treating mild brain injury
US9833411B2 (en)	2015-01-12	2017-12-05	Enteris Biopharma, Inc.	Solid oral dosage forms
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UA64751C2 (uk)	1997-06-25	2004-03-15	Пфайзер Продактс Інк.	Спосіб лікування інсулінової толерантності речовинами, які посилюють секрецію гормону росту (варіанти) та фармацевтична композиція (варіанти)
UA53716C2 (uk)	1997-06-25	2003-02-17	Пфайзер Продактс Інк.	Тартратна сіль заміщеного дипептиду, спосіб її одержання, проміжні сполуки та спосіб їх одержання, фармацевтична композиція (варіанти), спосіб підвищення рівнів ендогенного гормону росту та спосіб лікування або профілактики захворювань (варіанти)
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1998
- 1998-05-06 UA UA99127067A patent/UA53716C2/uk unknown
- 1998-06-05 IL IL13281098A patent/IL132810A0/xx unknown
- 1998-06-05 SK SK1772-99A patent/SK177299A3/sk unknown
- 1998-06-05 ES ES98921681T patent/ES2301196T3/es not_active Expired - Lifetime
- 1998-06-05 CA CA002294422A patent/CA2294422C/en not_active Expired - Lifetime
- 1998-06-05 JP JP50402799A patent/JP3414759B2/ja not_active Expired - Fee Related
- 1998-06-05 CN CNA2004100059410A patent/CN1524857A/zh active Pending
- 1998-06-05 US US09/380,886 patent/US6248717B1/en not_active Expired - Lifetime
- 1998-06-05 EP EP98921681A patent/EP0989993B1/en not_active Expired - Lifetime
- 1998-06-05 WO PCT/IB1998/000874 patent/WO1998058948A1/en not_active Ceased
- 1998-06-05 EA EA199901076A patent/EA002643B1/ru not_active IP Right Cessation
- 1998-06-05 PT PT98921681T patent/PT989993E/pt unknown
- 1998-06-05 AT AT98921681T patent/ATE388163T1/de not_active IP Right Cessation
- 1998-06-05 KR KR1019997012222A patent/KR100339936B1/ko not_active Expired - Fee Related
- 1998-06-05 DE DE69839211T patent/DE69839211T2/de not_active Expired - Lifetime
- 1998-06-05 NZ NZ500658A patent/NZ500658A/en unknown
- 1998-06-05 PL PL98337654A patent/PL337654A1/xx unknown
- 1998-06-05 DK DK98921681T patent/DK0989993T3/da active
- 1998-06-05 HU HU0002664A patent/HUP0002664A3/hu unknown
- 1998-06-05 AU AU74455/98A patent/AU744775B2/en not_active Ceased
- 1998-06-05 BR BRPI9810623-6A patent/BR9810623B1/pt not_active IP Right Cessation
- 1998-06-05 TR TR1999/03261T patent/TR199903261T2/xx unknown
- 1998-06-05 ID IDW991663A patent/ID23188A/id unknown
- 1998-06-05 CN CN98806559A patent/CN1314912A/zh active Pending
- 1998-06-11 PA PA19988453401A patent/PA8453401A1/es unknown
- 1998-06-18 GT GT199800085A patent/GT199800085A/es unknown
- 1998-06-18 AP APAP/P/1998/001266A patent/AP1043A/en active
- 1998-06-19 PE PE1998000540A patent/PE97599A1/es not_active Application Discontinuation
- 1998-06-22 TW TW087110024A patent/TWI221153B/zh not_active IP Right Cessation
- 1998-06-23 AR ARP980103022A patent/AR012255A1/es not_active Application Discontinuation
- 1998-06-23 UY UY25059A patent/UY25059A1/es not_active IP Right Cessation
- 1998-06-24 MA MA25138A patent/MA26516A1/fr unknown
- 1998-06-24 TN TNTNSN98111A patent/TNSN98111A1/fr unknown
- 1998-06-24 DZ DZ980148A patent/DZ2538A1/xx active
- 1998-06-25 HR HR60/050,723A patent/HRP980362A2/hr not_active Application Discontinuation
- 1998-06-25 CO CO98036378A patent/CO4810383A1/es unknown
- 1998-06-25 ZA ZA9805541A patent/ZA985541B/xx unknown
1999
- 1999-11-26 IS IS5276A patent/IS5276A/is unknown
- 1999-12-16 BG BG104024A patent/BG104024A/bg unknown
- 1999-12-21 OA OA9900299A patent/OA11241A/en unknown
- 1999-12-23 NO NO996469A patent/NO996469L/no not_active Application Discontinuation
2000
- 2000-12-11 US US09/734,269 patent/US6596867B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP2000514840A (ja)	2000-11-07
PA8453401A1 (es)	2000-05-24
HRP980362A2 (en)	1999-02-28
NO996469L (no)	2000-02-23
ATE388163T1 (de)	2008-03-15
EA002643B1 (ru)	2002-08-29
TWI221153B (en)	2004-09-21
DE69839211T2 (de)	2009-03-19
IS5276A (is)	1999-11-26
HUP0002664A2 (hu)	2000-12-28
BR9810623B1 (pt)	2010-06-15
EA199901076A1 (ru)	2000-08-28
US6248717B1 (en)	2001-06-19
AP1043A (en)	2002-02-04
AU7445598A (en)	1999-01-04
MA26516A1 (fr)	2004-12-20
IL132810A0 (en)	2001-03-19
JP3414759B2 (ja)	2003-06-09
TNSN98111A1 (fr)	2005-03-15
DZ2538A1 (fr)	2003-02-08
ES2301196T3 (es)	2008-06-16
CN1524857A (zh)	2004-09-01
CO4810383A1 (es)	1999-06-30
KR20010014153A (ko)	2001-02-26
PE97599A1 (es)	1999-10-12
AR012255A1 (es)	2000-09-27
CA2294422A1 (en)	1998-12-30
BG104024A (bg)	2000-07-31
ID23188A (id)	2000-03-23
UY25059A1 (es)	2000-12-29
DE69839211D1 (de)	2008-04-17
AP9801266A0 (en)	1998-06-30
PL337654A1 (en)	2000-08-28
PT989993E (pt)	2008-04-15
AU744775B2 (en)	2002-03-07
SK177299A3 (en)	2001-09-11
WO1998058948A1 (en)	1998-12-30
CA2294422C (en)	2003-07-22
ZA985541B (en)	2000-01-10
EP0989993A1 (en)	2000-04-05
NO996469D0 (no)	1999-12-23
HUP0002664A3 (en)	2001-12-28
NZ500658A (en)	2001-08-31
US6596867B2 (en)	2003-07-22
UA53716C2 (uk)	2003-02-17
US20010016570A1 (en)	2001-08-23
KR100339936B1 (ko)	2002-06-10
GT199800085A (es)	1999-12-10
TR199903261T2 (xx)	2000-08-21
CN1314912A (zh)	2001-09-26
DK0989993T3 (da)	2008-06-02
BR9810623A (pt)	2000-07-25
EP0989993B1 (en)	2008-03-05

Publication	Publication Date	Title
OA11241A (en)	2003-05-26	Tartrate salt of a substituted dipeptide as growthhormone secretagogue
JP3511382B2 (ja)	2004-03-29	成長ホルモン分泌促進物質
JP3676790B2 (ja)	2005-07-27	成長ホルモン分泌促進薬としてのジペプチド誘導体
EP1002802B1 (en)	2004-12-08	Dipeptide derivatives as growth hormone secretagogues
MXPA99012100A (en)	2000-09-04	Tartrate salt of a substituted dipeptide as growth hormone secretagogue
CZ458699A3 (cs)	2000-05-17	Vinanová sůl substituovaného dipeptidu jako sekretagog růstového hormonu
HK1036995A (en)	2002-01-25	Tartrate salt of a substituted dipeptide as growth hormone secretagogue