PH16607A - Tri-and tetracyclic imidazo(1,5-a)(1,4)diazepine derivatives and method of use - Google Patents

Tri-and tetracyclic imidazo(1,5-a)(1,4)diazepine derivatives and method of use

Info

Publication number: PH16607A
Authority: PH; Philippines
Prior art keywords: tri; diazepine derivatives; tetracyclic; imidazo; tetracyclic imidazo
Prior art date: 1979-10-04

Application number

PH24651A

Other languages

English (en)

Inventor

Willy Dr Haefely

Walter Dr Hunkeler

Emilio Dr Kyburz

Hanns Dr Mohler

Pieri Dr Lorenzo

Max Dr Gerecke

Polc Dr Petar

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-10-04

Filing date

1980-09-30

Publication date

1983-11-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27509256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH16607(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1980-09-30 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1983-11-24 Publication of PH16607A publication Critical patent/PH16607A/en

Links

IMXWNWBXKWASOM-UHFFFAOYSA-N 3h-imidazo[1,5-a][1,4]diazepine Chemical class N1=CC=CN2CN=CC2=C1 IMXWNWBXKWASOM-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/42—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms with nitro or nitroso radicals directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Toxicology (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

PH24651A 1979-10-04 1980-09-30 Tri-and tetracyclic imidazo(1,5-a)(1,4)diazepine derivatives and method of use PH16607A (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
CH897279		1979-10-04
CH897179		1979-10-04
CH1066479		1979-11-30
CH1066579		1979-11-30
CH571680		1980-07-25

Publications (1)

Publication Number	Publication Date
PH16607A true PH16607A (en)	1983-11-24

Family

ID=27509256

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH24651A PH16607A (en)	1979-10-04	1980-09-30	Tri-and tetracyclic imidazo(1,5-a)(1,4)diazepine derivatives and method of use

Country Status (23)

Country	Link
US (10)	US4316839A (fr)
EP (1)	EP0027214B1 (fr)
JP (1)	JPH01156968A (fr)
AR (1)	AR227293A1 (fr)
AU (1)	AU533641B2 (fr)
BR (1)	BR8006404A (fr)
CA (1)	CA1143728A (fr)
DE (1)	DE3067868D1 (fr)
DK (1)	DK168094B1 (fr)
FI (1)	FI73683C (fr)
GB (1)	GB2060632B (fr)
GR (1)	GR70772B (fr)
HU (1)	HU182675B (fr)
IE (1)	IE50318B1 (fr)
IL (1)	IL61160A (fr)
LU (1)	LU88298I2 (fr)
MC (1)	MC1355A1 (fr)
NL (1)	NL930056I2 (fr)
NO (1)	NO155774C (fr)
NZ (1)	NZ195071A (fr)
PH (1)	PH16607A (fr)
PT (1)	PT71874B (fr)
ZW (1)	ZW21580A1 (fr)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1143728A (fr) *	1979-10-04	1983-03-29	Max Gerecke	Derives d'imidazodiazepine
CA1185602A (fr) *	1981-02-27	1985-04-16	Emilio Kyburz	Imidazodiazepines
CA1174673A (fr) *	1981-02-27	1984-09-18	Walter Hunkeler	Imidazodiazepines
CA1173441A (fr) *	1981-02-27	1984-08-28	Hoffmann-La Roche Limited	Imidazodiazepines
US4352817A (en) *	1981-02-27	1982-10-05	Hoffmann-La Roche Inc.	Imidazo-diazepines and their use
CA1184175A (fr) *	1981-02-27	1985-03-19	Walter Hunkeler	Imidazodiazepines
MC1528A1 (fr) *	1982-07-21	1984-04-13	Hoffmann La Roche	Imidazobenzodiazepines
DK151808C (da) *	1982-11-16	1988-06-20	Ferrosan As	Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
US4723003A (en) *	1983-05-18	1988-02-02	Hoechst-Roussel Pharmaceuticals Inc.	Benzopyrrolobenzodiazepines and quinobenzodiazepines
DE3587913D1 (de) *	1984-01-19	1994-10-06	Hoffmann La Roche	Imidazodiazepin-Derivate.
AU587802B2 (en) *	1985-03-08	1989-08-31	Ferrosan A/S	Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4745112A (en) *	1985-05-17	1988-05-17	A/S Ferrosan	Oxadiazolylimidazobenzodiazepine, compositions, and method III
US4622320A (en) *	1985-05-17	1986-11-11	As Ferrosan	Oxadiazolylimidazobenzodiazepine, compositions, and method
DK174086D0 (da) *	1986-04-16	1986-04-16	Ferrosan As	Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
FI880814A7 (fi) *	1987-03-10	1988-09-11	Hoffmann La Roche	Imidazodiazepin-derivat.
GB8720414D0 (en) *	1987-08-28	1987-10-07	Roussel Lab Ltd	Chemical compounds
US5096695A (en) *	1988-08-05	1992-03-17	Hoffmann-Laroche Inc.	Radioiodine benzodiazepines as brain imaging agents
ES2052837T3 (es) *	1988-08-05	1994-07-16	Hoffmann La Roche	Derivados marcados radioactivamente de la benzodiazepina.
CA1327572C (fr) *	1988-08-31	1994-03-08	F. Hoffmann-La Roche Ag	Derives imidazodiazepine
GB8909700D0 (en) *	1989-04-27	1989-06-14	Roussel Lab Ltd	Chemical compounds
CA2015336A1 (fr) *	1989-05-19	1990-11-19	F. Hoffmann-La Roche Ag	Imidazodiazepines pour le traitement des symptomes neurologiques
FR2660310B1 (fr) *	1990-03-27	1992-06-05	Adir	Nouveaux derives de la 4h-pyrrolo[1,2a] thieno[2,3-f] diazepine[1,4], leur procede de preparation et les compositions pharmaceutiques les renfermant.
US5371080A (en) *	1990-06-22	1994-12-06	Novo Nordisk A/S	Imidazoquinazoline compounds and their use
US5276028A (en) *	1990-06-22	1994-01-04	Nordisk A/S	Imidazoquinoxaline compounds
TW201311B (fr) *	1991-06-17	1993-03-01	Hoffmann La Roche
US5250679A (en) *	1991-10-18	1993-10-05	Genentech, Inc.	Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
US5663166A (en) *	1991-10-18	1997-09-02	Genentech, Inc.	Nonpeptidyl integrin inhibitors having specificity for the GPIIb IIIa receptor
US5438035A (en) *	1994-06-24	1995-08-01	American Cyanamid Company	Methods for controlling undesirable plant species with benzodiazepine compounds
TW349100B (en) *	1994-11-11	1999-01-01	Hoffmann La Roche	Oxazolyl- and thiazolylimidazo-benzo- and thienodiazepines
US5670640A (en)	1996-02-02	1997-09-23	Hoffmann-La Roche Inc.	Process for the manufacture of imidazodiazepine derivatives
GB2328940B (en) *	1997-09-05	1999-12-08	Dong Kook Pharm Co Ltd	A process for preparing benzodiazepine derivatives
PL1691811T3 (pl)	2003-12-11	2014-12-31	Sunovion Pharmaceuticals Inc	Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
ATE402707T1 (de)	2004-10-12	2008-08-15	Hoffmann La Roche	Imidazoä1,5aütriazoloä1,5dübenzodiazepin- derivative zur behandlung kognitiver störungen
JP4751398B2 (ja)	2004-10-20	2011-08-17	エフ．ホフマン−ラロシュアーゲー	ハロゲン置換ベンゾジアゼピン誘導体
NZ554439A (en)	2004-10-20	2009-09-25	Hoffmann La Roche	Imidazo-benzodiazepine derivatives
MX2007007115A (es)	2004-12-14	2007-07-11	Hoffmann La Roche	Imidazo-benzodiazepinas tetraciclicas como moduladoras del receptor del acido gamma-aminobutirico (gaba).
EP1888594A2 (fr) *	2005-05-16	2008-02-20	Wisys Technology Foundation, Inc.	Agents gabaergiques utilises dans le traitement de troubles de la memoire
JP2009506069A (ja)	2005-08-26	2009-02-12	ブレインセルス，インコーポレイティド	ムスカリン性受容体調節による神経発生
EP2258359A3 (fr)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline
JP2009512711A (ja)	2005-10-21	2009-03-26	ブレインセルス，インコーポレイティド	Ｐｄｅ阻害による神経新生の調節
EP2314289A1 (fr)	2005-10-31	2011-04-27	Braincells, Inc.	Modulation de la neurogenese dont la médiation est assurée par récepteur gaba
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
CA2643199A1 (fr) *	2006-03-08	2007-09-13	Braincells, Inc.	Modulation de neurogenese par des agents nootropes
CA2651862A1 (fr)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenese induite par le recepteur 5ht
AU2007249399A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
US20100009983A1 (en) *	2006-05-09	2010-01-14	Braincells, Inc.	5 ht receptor mediated neurogenesis
WO2008030651A1 (fr) *	2006-09-08	2008-03-13	Braincells, Inc.	Combinaisons contenant un dérivé de 4-acylaminopyridine
AU2007299920A1 (en) *	2006-09-19	2008-03-27	Braincells, Inc.	PPAR Mediated Modulation of Neurogenesis
CA2696703C (fr)	2007-08-20	2016-07-26	Evotec Neurosciences Gmbh	Traitement de troubles du sommeil
US20090054412A1 (en) *	2007-08-20	2009-02-26	John Alan Kemp	Treatment of Sleep Disorders
US20090270373A1 (en) *	2008-04-11	2009-10-29	Cypress Biosciences, Inc.	Treatment of down syndrom with benzodiazepine receptor antagonists
US20100216805A1 (en)	2009-02-25	2010-08-26	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
GB0917612D0 (en) *	2009-10-08	2009-11-25	Ge Healthcare Ltd	In vivo imaging agents
RU2013139247A (ru) *	2011-02-23	2015-03-27	Церулеус Лтд.	Комплексы флумазенила, содержащие их композиции и их применения
CN102267999B (zh) *	2011-07-15	2013-05-29	海南美兰史克制药有限公司	一种氟马西尼化合物及其制法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3933794A (en) *	1971-08-04	1976-01-20	The Upjohn Company	2-(2-Alkynylamino)-3H-1,4-benzodiazepines
US4031079A (en) *	1975-09-22	1977-06-21	Mcneil Laboratories, Incorporated	Intermediates for 2-aminobenzodiazepine-5-ones
US4002610A (en) *	1975-09-22	1977-01-11	Mcneil Laboratories, Incorporated	2-Aminobenzodiazepine-5-ones
US4118386A (en) *	1977-04-04	1978-10-03	Hoffmann-La Roche Inc.	Synthesis of imidazo[1,5-a]diazepine-3-carboxylates
ZA806016B (en) *	1979-10-04	1981-09-30	Hoffmann La Roche	Imidazodiazepine derivatives
CA1143728A (fr) *	1979-10-04	1983-03-29	Max Gerecke	Derives d'imidazodiazepine
JPH089074B2 (ja) *	1987-07-02	1996-01-31	株式会社アマダ	タレツトパンチプレス

1980
- 1980-09-10 CA CA000360028A patent/CA1143728A/fr not_active Expired
- 1980-09-15 DK DK391280A patent/DK168094B1/da not_active IP Right Cessation
- 1980-09-19 ZW ZW215/80A patent/ZW21580A1/xx unknown
- 1980-09-26 NZ NZ195071A patent/NZ195071A/en unknown
- 1980-09-29 AU AU62782/80A patent/AU533641B2/en not_active Expired
- 1980-09-29 IL IL61160A patent/IL61160A/xx not_active IP Right Cessation
- 1980-09-30 PH PH24651A patent/PH16607A/en unknown
- 1980-10-01 HU HU802390A patent/HU182675B/hu unknown
- 1980-10-02 GR GR63031A patent/GR70772B/el unknown
- 1980-10-02 DE DE8080105970T patent/DE3067868D1/de not_active Expired
- 1980-10-02 EP EP80105970A patent/EP0027214B1/fr not_active Expired
- 1980-10-02 MC MC801474A patent/MC1355A1/fr unknown
- 1980-10-02 FI FI803135A patent/FI73683C/fi not_active IP Right Cessation
- 1980-10-03 GB GB8031902A patent/GB2060632B/en not_active Expired
- 1980-10-03 AR AR282769A patent/AR227293A1/es active
- 1980-10-03 US US06/193,775 patent/US4316839A/en not_active Expired - Lifetime
- 1980-10-03 PT PT71874A patent/PT71874B/pt unknown
- 1980-10-03 BR BR8006404A patent/BR8006404A/pt unknown
- 1980-10-03 NO NO802946A patent/NO155774C/no unknown
- 1980-10-03 IE IE2056/80A patent/IE50318B1/en not_active IP Right Cessation
1981
- 1981-11-16 US US06/321,821 patent/US4346033A/en not_active Expired - Lifetime
- 1981-11-16 US US06/321,942 patent/US4359420A/en not_active Expired - Lifetime
- 1981-11-16 US US06/321,492 patent/US4346031A/en not_active Expired - Lifetime
- 1981-11-16 US US06/321,519 patent/US4346032A/en not_active Expired - Lifetime
- 1981-11-16 US US06/322,031 patent/US4346035A/en not_active Expired - Lifetime
- 1981-11-16 US US06/321,491 patent/US4346030A/en not_active Expired - Lifetime
- 1981-11-16 US US06/321,941 patent/US4346034A/en not_active Expired - Lifetime
- 1981-11-16 US US06/322,091 patent/US4363762A/en not_active Expired - Lifetime
- 1981-11-16 US US06/322,113 patent/US4346036A/en not_active Expired - Lifetime
1988
- 1988-10-25 JP JP63267347A patent/JPH01156968A/ja active Granted
1993
- 1993-06-09 LU LU88298C patent/LU88298I2/fr unknown
- 1993-06-11 NL NL930056C patent/NL930056I2/nl unknown

Also Published As

Publication number	Publication date
IE50318B1 (en)	1986-04-02
NO802946L (no)	1981-04-06
DK391280A (da)	1981-04-05
NZ195071A (en)	1984-08-24
BR8006404A (pt)	1981-04-14
ZW21580A1 (en)	1981-04-29
DK168094B1 (da)	1994-02-07
PT71874A (en)	1980-11-01
FI73683B (fi)	1987-07-31
US4346035A (en)	1982-08-24
EP0027214A1 (fr)	1981-04-22
IE802056L (en)	1981-04-04
MC1355A1 (fr)	1981-08-10
GB2060632B (en)	1983-11-02
US4316839A (en)	1982-02-23
IL61160A0 (en)	1980-11-30
AU6278280A (en)	1981-04-09
US4346033A (en)	1982-08-24
NO155774C (no)	1987-05-27
AU533641B2 (en)	1983-12-01
US4363762A (en)	1982-12-14
US4346036A (en)	1982-08-24
CA1143728A (fr)	1983-03-29
FI803135L (fi)	1981-04-05
AR227293A1 (es)	1982-10-15
EP0027214B1 (fr)	1984-05-16
JPH01156968A (ja)	1989-06-20
JPH0369913B2 (fr)	1991-11-05
GB2060632A (en)	1981-05-07
US4346032A (en)	1982-08-24
NL930056I2 (nl)	1993-11-16
HU182675B (en)	1984-02-28
LU88298I2 (fr)	1994-05-04
US4346034A (en)	1982-08-24
DE3067868D1 (en)	1984-06-20
IL61160A (en)	1983-07-31
US4346030A (en)	1982-08-24
NO155774B (no)	1987-02-16
GR70772B (fr)	1983-03-22
US4359420A (en)	1982-11-16
NL930056I1 (nl)	1993-09-01
US4346031A (en)	1982-08-24
PT71874B (en)	1982-03-31
FI73683C (fi)	1987-11-09

Legal Events

Date	Code	Title	Description
1996-10-30	AT	Record of annual fee payments	Year of fee payment: 13

Publication	Publication Date	Title
PH16607A (en)	1983-11-24	Tri-and tetracyclic imidazo(1,5-a)(1,4)diazepine derivatives and method of use
PH19881A (en)	1986-08-13	Tetracyclic t-butyl imidazo(1,5-a)(1,4)-diazepine-1-carboxylates,medicament containing same and method of use thereof
IL83139A (en)	1993-01-14	1,2,4-triazolo (1,5-a) pyrimidine-2-sulfonyl chlorides and their preparation
ZA897699B (en)	1990-09-26	Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
DE3065270D1 (en)	1983-11-17	Substituted pyrazolo (1,5-a) pyrimidines, and their preparation
AU516873B2 (en)	1981-06-25	IMIDAZO[1, 5-a][1, 4]BENZODIAZEPINE DERIVATIVES
PH21839A (en)	1988-03-17	Imidazo derivatives and their method of use
HK60884A (en)	1984-08-10	Indolo(2,3-a)quinolizidines,preparation and therapeutic use
ZA806342B (en)	1982-05-26	Benzodiazepine compounds and their use as pharamceuticals
PH23147A (en)	1989-05-11	Imidazo/1,5-a/pyridine derivatives
DE3070304D1 (en)	1985-04-25	Thiazolo(3,2-a)pyrimidine derivatives, process for preparing same, and drug containing same
GB9410441D0 (en)	1994-07-13	Azabicycloakyl derivatives of imidazo (1,5-a) indol-3-one and process for their preparation
AR230748A1 (es)	1984-06-29	Procedimiento para la preparacion de derivados de imidazo(1,2-a)tien(3,2-d)pirimidim-6,9-(5h,7h)-diona y compuestos para su exclusivo uso como intermediarios en dicho procedimiento
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