PH27437A - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number: PH27437A
Authority: PH; Philippines
Prior art keywords: phenyl; lower alkyl; alkyl; alkoxy; formula
Prior art date: 1987-12-24

Application number

PH37977A

Other languages

English (en)

Inventor

Terence James Ward

Janet Christine White

Original Assignee

Wyeth John & Brother Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-24

Filing date

1988-12-23

Publication date

1993-07-02

1987-12-24 Priority claimed from GB878730193A external-priority patent/GB8730193D0/en

1988-08-19 Priority claimed from GB888819728A external-priority patent/GB8819728D0/en

1988-12-23 Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd

1993-07-02 Publication of PH27437A publication Critical patent/PH27437A/en

Links

150000002391 heterocyclic compounds Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 7
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 4
229910052736 halogen Inorganic materials 0.000 abstract 3
150000002367 halogens Chemical class 0.000 abstract 3
229910052760 oxygen Inorganic materials 0.000 abstract 3
229910052717 sulfur Inorganic materials 0.000 abstract 2
KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 1
150000001204 N-oxides Chemical class 0.000 abstract 1
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000004442 acylamino group Chemical group 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
239000004202 carbamide Substances 0.000 abstract 1
125000005518 carboxamido group Chemical group 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052727 yttrium Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Otolaryngology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PH37977A 1987-12-24 1988-12-23 Heterocyclic compounds PH27437A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878730193A GB8730193D0 (en)	1987-12-24	1987-12-24	Heterocyclic compounds
GB888819728A GB8819728D0 (en)	1988-08-19	1988-08-19	Heterocyclic compounds

Publications (1)

Publication Number	Publication Date
PH27437A true PH27437A (en)	1993-07-02

Family

ID=26293248

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH37977A PH27437A (en)	1987-12-24	1988-12-23	Heterocyclic compounds

Country Status (18)

Country	Link
US (2)	US4983600A (fr)
EP (2)	EP0323077B1 (fr)
JP (1)	JP2588265B2 (fr)
KR (1)	KR970009588B1 (fr)
AT (2)	ATE107304T1 (fr)
AU (1)	AU611976B2 (fr)
CA (1)	CA1334095C (fr)
DE (2)	DE3850255T2 (fr)
DK (2)	DK710488A (fr)
ES (2)	ES2053959T3 (fr)
FI (1)	FI95031C (fr)
GB (1)	GB2213816B (fr)
GR (1)	GR3002701T3 (fr)
HU (1)	HU204267B (fr)
IE (2)	IE63474B1 (fr)
IL (1)	IL88644A (fr)
PH (1)	PH27437A (fr)
PT (1)	PT89286B (fr)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
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DK443489D0 (da) *	1989-09-08	1989-09-08	Ferrosan As	Substituerede urinstofforbindelser, deres fremstilling og anvendelse
GB8922622D0 (en) *	1989-10-07	1989-11-22	Wyeth John & Brother Ltd	Aroylureas
GB2236751B (en)	1989-10-14	1993-04-28	Wyeth John & Brother Ltd	Heterocyclic compounds
DK40890D0 (da) *	1990-02-16	1990-02-16	Ferrosan As	Substituerede urinstofforbindelser, deres fremstilling og anvendelse
DE4009565A1 (de) *	1990-03-24	1991-09-26	Merck Patent Gmbh	Indolderivate
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US5223613A (en) *	1990-04-27	1993-06-29	G. D. Searle & Co.	Azatetracycle compounds and process of preparing same
JP3122671B2 (ja) *	1990-05-23	2001-01-09	協和醗酵工業株式会社	複素環式化合物
CA2097815C (fr) *	1990-12-28	2001-04-17	Fumio Suzuki	Derive de la quinoline
EP0573522B1 (fr) *	1991-03-01	1994-12-14	Pfizer Inc.	Derives de 1-azabicyclo[3.2.2]nonan-3-amine
US5516782A (en) *	1991-03-07	1996-05-14	G. D. Searle & Co.	New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
US5219850A (en) *	1991-03-07	1993-06-15	G. D. Searle & Co.	Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5260303A (en) *	1991-03-07	1993-11-09	G. D. Searle & Co.	Imidazopyridines as serotonergic 5-HT3 antagonists
US5137893A (en) *	1991-03-07	1992-08-11	G. D. Searle & Co.	Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
CA2082415A1 (fr) *	1991-03-07	1992-09-08	Daniel P. Becker	Amides et esters acides aromatiques mesoazacycliques utilises comme nouveaux agents serotoninergiques
US5234921A (en) *	1991-03-07	1993-08-10	G. D. Searle & Co.	Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals
US5196547A (en) *	1991-03-07	1993-03-23	G. D. Searle & Co.	Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof
US5227377A (en) *	1991-03-07	1993-07-13	G. D. Searle & Co.	Meso-azacyclic amides of certain bicyclic carboxylic acids
GB9121835D0 (en) *	1991-10-15	1991-11-27	Smithkline Beecham Plc	Pharmaceuticals
JPH05310732A (ja) *	1992-03-12	1993-11-22	Mitsubishi Kasei Corp	シンノリン−３−カルボン酸誘導体
US5244907A (en) *	1992-03-26	1993-09-14	A. H. Robins Company, Incorporated	Carbocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
US5190953A (en) *	1992-03-26	1993-03-02	A. H. Robins Company, Incorporated	Heterocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
ES2141763T3 (es) *	1992-03-31	2000-04-01	Glaxo Group Ltd	Fenilcarbonatos y fenilureas sustituidos, su preparacion y su uso como antagonistas de 5-ht4.
GB9206989D0 (en) *	1992-03-31	1992-05-13	Glaxo Group Ltd	Chemical compounds
GB9217629D0 (en) *	1992-08-19	1992-09-30	Wyeth John & Brother Ltd	Aroylureas
GB2269747B (en) *	1992-08-19	1996-06-05	Wyeth John & Brother Ltd	Aroyl-ureas as pharmaceuticals, particularly 5-ht3 antagonists
GB9224144D0 (en) *	1992-11-18	1993-01-06	Erba Carlo Spa	Phenyl-imidazolidinone derivatives and process for their preparation
GB9314174D0 (en) *	1993-07-08	1993-08-18	American Home Prod	5-ht3-antagonists
DE69739869D1 (de) *	1996-03-20	2010-06-17	Univ Wake Forest Health Sciences	Sigma-2 rezeptoren als biomarkierer der tumorzellenproliferation
US6676925B1 (en) *	1996-03-20	2004-01-13	Wake Forest University	Sigma-2 receptors as biomarkers of tumor cell proliferation
SE510305C2 (sv) *	1997-05-30	1999-05-10	Astra Ab	Nytt salt
US6022884A (en)	1997-11-07	2000-02-08	Amgen Inc.	Substituted pyridine compounds and methods of use
DE60101570T2 (de)	2000-04-27	2004-09-30	Wake Forest University Health Sciences	Sigma-2 rezeptoren als biomarkierer der tumorzellenproliferation
US6492385B2 (en)	2000-08-18	2002-12-10	Pharmacia & Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
US6479510B2 (en)	2000-08-18	2002-11-12	Pharmacia & Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
AU2001282873A1 (en)	2000-08-18	2002-03-04	Pharmacia And Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
AU2001284646A1 (en)	2000-08-21	2002-03-04	Pharmacia And Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
US6500840B2 (en)	2000-08-21	2002-12-31	Pharmacia & Upjohn Company	Quinuclidine-substituted heteroaryl moieties for treatment of disease
PE20021019A1 (es)	2001-04-19	2002-11-13	Upjohn Co	Grupos azabiciclicos sustituidos
AR036041A1 (es) *	2001-06-12	2004-08-04	Upjohn Co	Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
AR036040A1 (es)	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
US6562816B2 (en)	2001-08-24	2003-05-13	Pharmacia & Upjohn Company	Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease
CA2455773A1 (fr) *	2001-08-24	2003-03-06	Pharmacia & Upjohn Company	Aryl 7-aza¬2.2.1\|bicycloheptanes substitues utiles dans le traitement de maladies
BR0212477A (pt) *	2001-09-12	2004-08-24	Upjohn Co	7-aza[2.2.1] bicicloheptanos substituìdos para o tratamento de doenças
MXPA04003007A (es)	2001-10-02	2004-07-15	Upjohn Co	Compuestos azabiciclico sustituidos condensados con heteroarilo para el tratamiento de enfermedades.
US6849620B2 (en)	2001-10-26	2005-02-01	Pfizer Inc	N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
WO2003037896A1 (fr) *	2001-10-26	2003-05-08	Pharmacia & Upjohn Company	Carboxamides hetero-bicycliques substitues par n-azabicyclo, utilises en tant qu'agonistes du recepteur de l'acetylcholine nicotinique
MXPA04004464A (es) *	2001-11-08	2004-08-11	Upjohn Co	Compuestos de heteroarilo sustituido con azabiciclo para el tratamiento de enfermedades.
WO2003042210A1 (fr)	2001-11-09	2003-05-22	Pharmacia & Upjohn Company	Composes heterocycliques fusionnes avec un groupe phenyl-azabicyclique et leur utilisation en tant que ligands de recepteur nachr alpha 7
US6852716B2 (en)	2002-02-15	2005-02-08	Pfizer Inc	Substituted-aryl compounds for treatment of disease
WO2003070731A2 (fr) *	2002-02-19	2003-08-28	Pharmacia & Upjohn Company	Composes azabicycliques servant a traiter des maladies
WO2003070732A1 (fr) *	2002-02-19	2003-08-28	Pharmacia & Upjohn Company	Carboxamides hetero-aromatiques n-pontes bicycliques condenses destines au traitement de maladies
EP1478646A1 (fr) *	2002-02-20	2004-11-24	PHARMACIA & UPJOHN COMPANY	Composes azabicycliques presentant une activite de recepteurs d'alfa 7 nicotinique acetylcholine
US7176198B2 (en) *	2002-08-01	2007-02-13	Pfizer Inc.	1H-pyrazole and 1H-pyrrole-azabicyclic compounds for the treatment of disease
JP2006506395A (ja) *	2002-11-01	2006-02-23	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	ＣＮＳ疾患の治療のための、α７ニコチンアゴニスト活性及び５ＨＴ３アンタゴニスト活性を有する化合物
US20070155780A1 (en) *	2004-04-15	2007-07-05	Hitoshi Nakata	Stabilized composition containing 4-amino-5-chloro-n-[(1r, 3r, 5s)-8-methyl-8-azabicyclo[3.2.1]oct-3-y1]-2-[1-methylbut-2-ynyloxy]benzamide
MY173998A (en)	2011-03-18	2020-03-03	Genzyme Corp	Glucosylceramide synthase inhibitors
JOP20130273B1 (ar)	2012-09-11	2021-08-17	Genzyme Corp	مثبطات انزيم (سينثاز) غلوكوسيل سيراميد
PT3920912T (pt)	2019-02-04	2025-09-09	Genzyme Corp	Tratamento de ciliopatias usando inibidores da glucosilceramida sintase (gcs)
EP4100009A1 (fr)	2020-02-03	2022-12-14	Genzyme Corporation	Méthodes de traitement de symptômes neurologiques associés à des maladies lysosomales
CA3186766A1 (fr)	2020-07-24	2022-01-27	Danielle Combessis	Compositions pharmaceutiques comprenant du venglustat

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EP0099194A3 (fr) *	1982-07-03	1984-04-11	Beecham Group Plc	Benzamides
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CA1260474A (fr) *	1984-12-03	1989-09-26	Raymond A. Stokbroekx	Derives de benzoxazol- et de benzothiazolamine
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1988
- 1988-12-08 IE IE102988A patent/IE63474B1/en not_active IP Right Cessation
- 1988-12-08 AU AU26702/88A patent/AU611976B2/en not_active Ceased
- 1988-12-08 IE IE366188A patent/IE62231B1/en not_active IP Right Cessation
- 1988-12-09 CA CA000585519A patent/CA1334095C/fr not_active Expired - Fee Related
- 1988-12-09 IL IL88644A patent/IL88644A/xx not_active IP Right Cessation
- 1988-12-12 HU HU886399A patent/HU204267B/hu not_active IP Right Cessation
- 1988-12-14 AT AT89202801T patent/ATE107304T1/de not_active IP Right Cessation
- 1988-12-14 ES ES89202801T patent/ES2053959T3/es not_active Expired - Lifetime
- 1988-12-14 DE DE3850255T patent/DE3850255T2/de not_active Expired - Fee Related
- 1988-12-14 EP EP88311802A patent/EP0323077B1/fr not_active Expired - Lifetime
- 1988-12-14 EP EP89202801A patent/EP0361629B1/fr not_active Expired - Lifetime
- 1988-12-14 AT AT88311802T patent/ATE67200T1/de not_active IP Right Cessation
- 1988-12-14 ES ES88311802T patent/ES2051867T3/es not_active Expired - Lifetime
- 1988-12-14 DE DE8888311802T patent/DE3864807D1/de not_active Expired - Fee Related
- 1988-12-14 GB GB8829164A patent/GB2213816B/en not_active Expired - Fee Related
- 1988-12-20 DK DK710488A patent/DK710488A/da not_active Application Discontinuation
- 1988-12-21 FI FI885917A patent/FI95031C/fi not_active IP Right Cessation
- 1988-12-21 PT PT89286A patent/PT89286B/pt not_active IP Right Cessation
- 1988-12-22 JP JP63324701A patent/JP2588265B2/ja not_active Expired - Fee Related
- 1988-12-22 KR KR1019880017218A patent/KR970009588B1/ko not_active Expired - Fee Related
- 1988-12-23 PH PH37977A patent/PH27437A/en unknown
1989
- 1989-10-16 US US07/421,920 patent/US4983600A/en not_active Expired - Lifetime
- 1989-12-19 US US07/453,000 patent/US5106843A/en not_active Expired - Lifetime
1991
- 1991-09-12 GR GR91401252T patent/GR3002701T3/el unknown
1993
- 1993-07-08 DK DK93827A patent/DK82793D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK710488A (da)	1989-06-25
EP0323077A1 (fr)	1989-07-05
GB2213816A (en)	1989-08-23
DE3864807D1 (de)	1991-10-17
IE63474B1 (en)	1995-04-19
JPH01203365A (ja)	1989-08-16
IL88644A (en)	1993-05-13
EP0361629A3 (en)	1990-06-13
DE3850255D1 (de)	1994-07-21
GB2213816B (en)	1991-05-08
DE3850255T2 (de)	1994-09-22
JP2588265B2 (ja)	1997-03-05
GB8829164D0 (en)	1989-01-25
US4983600A (en)	1991-01-08
HU204267B (en)	1991-12-30
ATE67200T1 (de)	1991-09-15
ES2051867T3 (es)	1994-07-01
AU2670288A (en)	1989-06-29
FI95031C (fi)	1995-12-11
IL88644A0 (en)	1989-07-31
HUT53101A (en)	1990-09-28
US5106843A (en)	1992-04-21
EP0361629B1 (fr)	1994-06-15
DK82793A (da)	1993-07-08
GR3002701T3 (en)	1993-01-25
PT89286A (pt)	1989-12-29
KR890009923A (ko)	1989-08-04
DK710488D0 (da)	1988-12-20
PT89286B (pt)	1994-11-30
CA1334095C (fr)	1995-01-24
IE883661L (en)	1989-05-24
AU611976B2 (en)	1991-06-27
EP0361629A2 (fr)	1990-04-04
DK82793D0 (da)	1993-07-08
FI95031B (fi)	1995-08-31
EP0323077B1 (fr)	1991-09-11
IE62231B1 (en)	1995-01-11
FI885917A7 (fi)	1989-06-25
ES2053959T3 (es)	1994-08-01
IE881029L (en)	1989-06-24
KR970009588B1 (ko)	1997-06-14
ATE107304T1 (de)	1994-07-15

Publication	Publication Date	Title
GB2213816B (en)	1991-05-08	Heterocyclic compounds
ATE542805T1 (de)	2012-02-15	Ppar-delta aktivatoren
DK359289D0 (da)	1989-07-19	4-oxoquinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf samt deres anvendelse
AU4929690A (en)	1990-08-16	Phenyl pyradazine-3(2H)one, thiadizin-2(3H)one, triazin-3(2H) one and oxadiazin-5(4H)one derivatives for the treatment of congestive heart failure
DE19875001I2 (de)	2001-11-22	Antibakterielle Chinolin-Verbindungen
IL98745A (en)	1997-03-18	Thioalkylthio cephalosporins and process for their preparation
DK189988A (da)	1988-10-08	Pyridylalkansyreforbindelser med aktivitet som thromboxan a2-antagonister
EP0341081A3 (en)	1990-12-27	Novel amino acid derivatives
ZA883067B (en)	1988-12-28	Anilide herbicides
IE821191L (en)	1982-11-20	N-(arylthioalkyl)-n'-(aminoalkyl)ureas
FR2257581A1 (en)	1975-08-08	Herbicidal thiadiazolyl imidazolidinones - 1-(2-alkyl-(1,3,4)thiadiazol-5-yl)-3-(halo)alkylimidazolidine-2-o- nes
ES8800930A1 (es)	1987-12-01	Un metodo de preparacion de un compuesto de oxodiazina
HUT39173A (en)	1986-08-28	Process for production of derivatives of 3-hydro-amino-2,3-dihydro-benzoxepin
ES8501729A1 (es)	1984-12-01	Un metodo de preparar fenoxialcanodionas sustituidas.
IT1056077B (it)	1982-01-30	Diazolidine tiadiazol sostituite e composizioni diserbantiche le contengono
NL7317578A (en)	1975-06-24	Herbicidal thiadiazolyl imidazolidinones - 1-(2-alkyl-(1,3,4)thiadiazol-5-yl)-3-(halo)alkylimidazolidine-2-o- nes
IE34651B1 (en)	1975-07-09	Nitrogen-containing heterocyclic compounds and their preparation
HUT50564A (en)	1990-03-28	Animal keeping pig-pen particularly for dropping swine and after-breeding of piglets
ES8707500A1 (es)	1987-08-16	Procedimiento para la obtencion de isocianatos piperidinicos.
SE8703060D0 (sv)	1987-08-05	Para-klor-n-(3-morfolinopropyl)bensamid, hydroklorid av densamma, forfarande for framstellning av desamma och lekemedelspreparat med antidepressiv och psykostimulerande verkan innehallande (para-klor-n-(3-morfolinopropy