PH31630A - Intermediates in the asymmetric synthesis of 3-substituted furanoside compounds. - Google Patents

Intermediates in the asymmetric synthesis of 3-substituted furanoside compounds.

Info

Publication number
PH31630A
PH31630A PH49766A PH49766A PH31630A PH 31630 A PH31630 A PH 31630A PH 49766 A PH49766 A PH 49766A PH 49766 A PH49766 A PH 49766A PH 31630 A PH31630 A PH 31630A
Authority
PH
Philippines
Prior art keywords
intermediates
compounds
asymmetric synthesis
substituted furanoside
furanoside compounds
Prior art date
Application number
PH49766A
Other languages
English (en)
Inventor
Yuri E Raifeld
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PH31630A publication Critical patent/PH31630A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/02—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/04—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C07C247/02—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/08—Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/42—Halogenated unsaturated alcohols acyclic
    • C07C33/423—Halogenated unsaturated alcohols acyclic containing only double bonds as unsaturation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/003—Compounds containing elements of Groups 4 or 14 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH49766A 1991-05-10 1995-01-10 Intermediates in the asymmetric synthesis of 3-substituted furanoside compounds. PH31630A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/698,042 US5216145A (en) 1991-05-10 1991-05-10 Asymmetric synthesis of 3-substituted furanoside compounds

Publications (1)

Publication Number Publication Date
PH31630A true PH31630A (en) 1999-01-12

Family

ID=24803685

Family Applications (1)

Application Number Title Priority Date Filing Date
PH49766A PH31630A (en) 1991-05-10 1995-01-10 Intermediates in the asymmetric synthesis of 3-substituted furanoside compounds.

Country Status (24)

Country Link
US (2) US5216145A (pl)
EP (1) EP0540807B1 (pl)
JP (1) JPH05170782A (pl)
KR (1) KR920021526A (pl)
CN (1) CN1032062C (pl)
AT (1) ATE132125T1 (pl)
AU (1) AU657129B2 (pl)
CA (1) CA2068226A1 (pl)
CZ (1) CZ283306B6 (pl)
DE (1) DE69207154T2 (pl)
DK (1) DK0540807T3 (pl)
ES (1) ES2083608T3 (pl)
FI (1) FI922097L (pl)
GR (1) GR3018671T3 (pl)
HU (1) HU209838B (pl)
IE (1) IE75888B1 (pl)
IL (3) IL101799A (pl)
NO (1) NO178113C (pl)
NZ (1) NZ242639A (pl)
PH (1) PH31630A (pl)
PL (1) PL168588B1 (pl)
SK (1) SK279311B6 (pl)
TW (1) TW223068B (pl)
ZA (1) ZA923350B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216145A (en) * 1991-05-10 1993-06-01 American Cyanamid Company Asymmetric synthesis of 3-substituted furanoside compounds
US5521294A (en) * 1995-01-18 1996-05-28 Eli Lilly And Company 2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides
CN101076536A (zh) * 2004-07-30 2007-11-21 药华医药股份有限公司 β-核苷的立体选择性合成
WO2006119347A1 (en) * 2005-05-02 2006-11-09 Pharmaessentia Corp. STEREOSELECTIVE SYNTHESIS OF β-NUCLEOSIDES
KR20100102107A (ko) * 2007-11-06 2010-09-20 파마이센시아 코퍼레이션 β-뉴클레오시드의 새로운 합성 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216145A (en) * 1991-05-10 1993-06-01 American Cyanamid Company Asymmetric synthesis of 3-substituted furanoside compounds

Also Published As

Publication number Publication date
FI922097A7 (fi) 1992-11-11
TW223068B (pl) 1994-05-01
NO921837L (no) 1992-11-11
IL101799A0 (en) 1992-12-30
IL101799A (en) 1998-04-05
ES2083608T3 (es) 1996-04-16
SK279311B6 (sk) 1998-09-09
EP0540807A1 (en) 1993-05-12
KR920021526A (ko) 1992-12-18
AU1613292A (en) 1992-11-12
FI922097A0 (fi) 1992-05-08
NZ242639A (en) 1993-10-26
US5216145A (en) 1993-06-01
CA2068226A1 (en) 1992-11-11
CZ283306B6 (cs) 1998-02-18
EP0540807B1 (en) 1995-12-27
CN1032062C (zh) 1996-06-19
JPH05170782A (ja) 1993-07-09
AU657129B2 (en) 1995-03-02
IE75888B1 (en) 1997-09-24
DE69207154D1 (de) 1996-02-08
IL116971A (en) 1999-03-12
HU9201546D0 (en) 1992-07-28
NO921837D0 (no) 1992-05-08
IE921483A1 (en) 1992-11-18
PL168588B1 (pl) 1996-03-29
HU209838B (en) 1994-11-28
FI922097L (fi) 1992-11-11
CS138692A3 (en) 1992-11-18
ZA923350B (en) 1993-01-27
NO178113B (no) 1995-10-16
GR3018671T3 (en) 1996-04-30
US5296620A (en) 1994-03-22
DK0540807T3 (da) 1996-01-29
DE69207154T2 (de) 1996-09-05
IL116971A0 (en) 1996-05-14
NO178113C (no) 1996-01-24
ATE132125T1 (de) 1996-01-15
CN1066658A (zh) 1992-12-02
HUT61562A (en) 1993-01-28

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